Allele Frequencies in World Populations

HLA Database » Allele Report

The list below shows all populations in AFND that contains the allele. If an allele has an entry with a lower resolution this will be shown at the end.



Allele reported 345 time(s) and present in 289 population(s).

Population Phenotype
Frequency (%)
Distribution² Haplotype³
GBRUnited Kingdom pop 20.1500101See
VENVenezuela Zulia San Jose de Heras Mixed0.125020See
TZATanzania Dodoma Kongwa0.1240212See
ZAFSouth Africa Tswana19.50.110041See
CMRCameroon Uldeme0.100035See
VENVenezuela Caracas Mestizo0.060050See
PAKPakistan Karachi Parsi0.060091See
MEXMexico Queretaro Rural0.058143See
USAUSA OPTN African American0.05701510See
MEXMexico Colima Rural0.056843See
MARMorocco pop 20.0550110See
MEXMexico Queretaro, Queretaro city0.044445See
MEXMexico Veracruz, Orizaba0.041760See
MEXMexico San Luis Potosi Rural0.040287See
TTOTrinidad African0.040067See
MEXMexico Hidalgo, Pachuca0.036641See
ESPSpain North Cantabria0.036083See
VENVenezuela Valencia and Maracaibo Caracus Mixed0.036096See
SDNSudan Khartoum0.035798See
BRABrazil Minas Gerais State Mixed6.50.03401000See
MEXMexico San Luis Potosi, San Luis Potosi city0.033330See
MEXMexico Chiapas Rural0.0331121See
MEXMexico Nayarit Rural0.031364See
BRABrazil Pernambuco Mixed0.0300101See
BRABrazil Parana Mixed race5.90.0300186See
CMRCameroon Bamileke 20.029035See
MEXMexico Jalisco, Tonala0.028635See
MEXMexico Chihuahua, Ciudad Juarez0.0278106See
MEXMexico Guanajuato Rural0.0276162See
BRABrazil REDOME Bahia0.027247399See
ESPSpain Pas Valley0.027088See
BRABrazil Rio Grande do Sul Black0.0260248See
MEXMexico Sonora, Hermosillo0.025399See
ESPSpain Sevilla5.00.0252278See
BRABrazil REDOME Acre0.0250859See
PAKPakistan Mixed Sindhi0.0250101See
PRTPortugal Center pop 20.0250562See
VENVenezuela Zulia Maracaibo Mixed0.025020See
BRABrazil REDOME Sergipe0.02457321See
MEXMexico Michoacan Rural0.0244348See
COLColombia Barranquilla0.0240188See
MEXMexico Zacatecas, Fresnillo0.0238103See
MEXMexico Zacatecas, Zacatecas city0.023884See
CUBCuba Mixed pop 20.0230189See
MEXMexico Jalisco, Guadalajara city0.02261189See
BRABrazil REDOME Minas Gerais0.0222211275See
USAUSA OPTN Hispanic0.02201580See
ISRIsrael Moroccan Jews0.0220113See
MEXMexico Tamaulipas, Ciudad Victoria0.021723See
MEXMexico Tabasco Rural0.0211142See
MEXMexico Chihuahua Chihuahua City0.0210119See
USAUSA African American Bethesda4.20.0210187See
PRTPortugal Viana do Castelo0.0210706See
BRABrazil REDOME Rio de Janeiro0.0209139322See
BRABrazil Para Cord Blood Unit4.20.0208841See
BRABrazil REDOME Goias0.020688574See
BRABrazil REDOME Piaui0.020446140See
BRABrazil REDOME Pernambuco0.020292332See
DZAAlgeria pop 24.00.0202106See
BRABrazil Sao Paulo Mixed0.40.0200239See
PRTPortugal Vila Real0.02001167See
ITAItaly East Sicily4.00.020050See
MEXMexico Baja California, Tijuana0.020025See
MEXMexico Baja California Rural0.020050See
BRABrazil REDOME Tocantins0.019820692See
BRABrazil REDOME Alagoas0.019625349See
MEXMexico Jalisco Rural0.0196585See
BRABrazil REDOME Federal District0.019429549See
BRABrazil REDOME Maranhao0.019210180See
MEXMexico Guanajuato, Leon0.019278See
BRABrazil South East Cord Blood0.019211409See
BRABrazil REDOME Rondonia0.019054396See
BRABrazil Rio Grande do Norte Mestizo0.019012973See
BRABrazil Piaui Mixed0.019021943See
PRTPortugal Viseu0.01902915See
PRTPortugal Beja0.0190699See
PRTPortugal Faro0.01901242See
BRABrazil Parana Afro Brazilian3.90.019077See
BRABrazil REDOME Amapa0.018617864See
BRABrazil REDOME Rio Grande do Norte0.018646603See
GBRUnited Kingdom East0.0186163See
BRABrazil REDOME Mato Grosso do Sul0.018395667See
MEXMexico Durango Rural0.0183326See
PRTPortugal Evora0.0180737See
PRTMadeira pop 30.0180538See
BRABrazil REDOME Mato Grosso0.017934649See
BRABrazil REDOME Espirito Santo0.017988485See
MEXMexico Veracruz, Coatzacoalcos0.017955See
MEXMexico Jalisco, Zapopan0.0179168See
BRABrazil Para State3.90.01785000See
MEXMexico Oaxaca Rural0.0175485See
BRABrazil REDOME Paraiba0.017543868See
BRABrazil REDOME Sao Paulo0.0172800809See
BRABrazil Paraná Caucasian3.40.0172641See
BRABrazil REDOME Ceara0.0171101217See
PRTPortugal Bragança0.0170301See
BRABrazil REDOME Roraima0.01684140See
MEXMexico Sinaloa Capomos Mayo Yoremes0.016760See
MEXMexico Sinaloa Rural0.0164183See
CHLChile Santiago0.0163920See
BRABrazil REDOME Para0.016372637See
IRNIran pop 10.016064See
MEXMexico Veracruz, Xalapa0.0160187See
BRABrazil Parana Cafuzo3.10.0160319See
FRAFrance Southeast3.10.0160130See
GTMGuatemala, Guatemala City Mixed Ancestry3.20.0157127See
MEXMexico Nayarit, Tepic0.015597See
MEXMexico Mayan Pop 30.015066See
CUBCuba Mixed0.015078See
GAZGaza Palestinians0.0150165See
MEXMexico Puebla Mestizo0.015099See
BRABrazil Belem Mixed3.00.0150100See
MEXMexico Mestizo pop 40.0149269See
MEXMexico Campeche, Campeche city0.014734See
ESPSpain, Castilla y Leon, Northwest,3.10.01451743See
BRABrazil REDOME Parana0.0143341639See
BRABrazil REDOME Amazonas0.014124129See
PRTPortugal North pop 20.01401801See
PRTPortugal Setubal0.01405268See
BRABrazil Sao Paulo Bauru Mixed0.01403542See
PRTPortugal Braga0.01401971See
PRTPortugal Lisbon0.014017420See
MEXMexico Veracruz Rural0.0139539See
MEXMexico Coahuila, Saltillo0.013772See
CZECzech Republic Kurd2.70.013574See
MEXMexico Mexico City North0.0133751See
BRABrazil Rio Grande do Sul Mixed0.0130324See
RUSRussia, South Ural, Chelyabinsk region, Nagaybaks2.70.0130112See
ARGArgentina Corrientes2.60.0130155See
CMRCameroon Ewondo0.013038See
PRTPortugal Guarda0.0130797See
MEXMexico Yucatan, Merida0.0128192See
ECUEcuador Coast Mixed Ancestry0.0126238See
BRABrazil REDOME Rio Grande do Sul0.0124241329See
MEXMexico Tabasco, Villahermosa0.012282See
CMRCameroon Podokwo0.012043See
PRTPortugal Portalegre0.01201254See
PRTPortugal Porto0.01207937See
PRTPortugal Santarem0.01203865See
PRTPortugal South pop 20.01201021See
PRTAzores Terceira Island0.0120130See
ESPSpain Murcia0.0120173See
MEXMexico Tamaulipas Rural0.0119125See
VENVenezuela Colonia Tovar0.011686See
MEXMexico Puebla Rural0.0114833See
MEXMexico Coahuila, Torreon0.0113396See
MEXMexico Zacatecas Rural0.0112266See
MEXMexico Veracruz, Poza Rica0.011145See
BRABrazil South Ribeirao Preto0.0110184See
PRTPortugal North0.011046See
ARGArgentina Buenos Aires pop 22.10.01101216See
PRTPortugal Leiria0.01101847See
MEXMexico Guerrero state0.0104144See
BRABrazil REDOME Santa Catarina0.0101106673See
IRQIraq Arabs2.00.0101149See
MEXMexico Quintana Roo Rural0.010050See
BRABrazil Rio Grande do Sul Caucasoid0.01004428See
PRTPortugal Coimbra0.01005057See
BRABrazil Parana Caucasian1.90.01002775See
ITAItaly Rome2.00.0100100See
PERPeru Arequipa Mestizo2.00.0100168See
MEXMexico Mexico City Metropolitan Area Rural0.0099150See
MEXMexico Sinaloa, Culiacán0.0097103See
FRAFrance Marseille2.00.00971000See
MEXMexico Chiapas, Tuxtla Gutierrez0.009452See
ECUEcuador Mixed Ancestry0.00941173See
ENGEngland North West Mixed pop 21.90.0092379See
WALWales pop 21.90.009039979See
MEXMexico Sinaloa Mestizo0.009056See
ARGArgentina Buenos Aires1.70.0090466See
PRTMadeira pop 20.0090173See
ITAItaly North Pavia pop 21.80.00902416See
MEXMexico Nuevo Leon, Monterrey city0.0089226See
MEXMexico Veracruz, Veracruz city0.0087171See
SWESweden Uppsala1.70.0085300See
ECUEcuador Andes Mixed Ancestry0.0085824See
MEXMexico Chihuahua Rural0.0084236See
MEXMexico Tlaxcala, Tlaxcala city0.0083181See
MEXMexico Colima, Colima city0.008261See
MEXMexico Mexico City Mestizo0.0080121See
PRTPortugal Aveiro0.00805933See
USAUSA OPTN Caucasian0.00808525See
MEXMexico Mexico City Mestizo pop 30.0080256See
MEXMexico Yucatan Rural0.0075132See
ENGEngland Leeds1.50.00755024See
ENGEngland Newcastle1.50.00752739See
ITAItaly North Pavia pop 30.0071685See
KURIraq Kurdistan Region1.40.0070209See
FRAFrance Lyon1.40.00704813See
ENGEngland Liverpool1.40.00701343See
TURTurkey pop 50.0070142See
RUSRussia Transbaikal Territory Buryats1.00.0070150See
MEXMexico Tapachula, Chiapas Mestizo Population1.40.007072See
MEXMexico Coahuila Rural0.0069216See
FRAFrance Bordeaux1.40.0068990See
MEXMexico Puebla, Puebla city0.00681994See
FRAFrance Rennes pop 41.40.00671000See
MEXMexico Baja California, La Paz0.006775See
MEXMexico Michoacan, Morelia0.0066150See
MEXMexico Mexico City Center0.0065152See
MEXMexico Durango, Durango city0.0065153See
MEXMexico Hidalgo Rural0.006281See
BRABrazil Curitiba-Parana Mixed0.0062264See
MEXMexico Morelos, Cuernavaca0.006182See
GBRUnited Kingdom Orkney0.006088See
SAUSaudi Arabia pop 41.20.0060499See
ENGEngland Sheffield1.20.00604755See
ESPSpain Majorca and Minorca0.006090See
ITAItaly South Campania Region1.20.00601089See
BRABrazil Parana Japanese1.00.0053192See
MEXMexico Sonora Rural0.0051197See
ITAItaly Lombardy1.00.0050674See
MARMorocco Casablanca0.0050100See
ARGArgentina Cuyo Region0.90.0050420See
ITAItaly Sardinia pop30.0050100See
ENGEngland Manchester1.00.00501640See
MYSMalaysia Perak and Johor Banjar Bugis Jawa0.005094See
FRAFrance Rennes pop 30.0050200See
FRAFrance Reims0.0050102See
ESPSpain North1.00.0050156See
PRTPortugal Castelo Branco0.0050327See
MNGMongolia Khalkha pop 20.0050202See
AUSAustralia West Caucasian1.00.0050891See
ESPSpain Minorca0.005094See
ROMRomania pop 31.00.00481469See
MEXMexico Tlaxcala Rural0.0048830See
SVKSlovakia pop 20.00464234See
GBRUnited Kingdom North0.0046330See
NORNorway ethnic Norwegians0.90.00454510See
ENGEngland Lancaster0.90.0045545See
MEXMexico Nuevo Leon Rural0.0045439See
FRAFrance Grenoble0.80.00411000See
CHNChina Jiangsu Province0.004020248See
USAUSA OPTN Asian0.0040261See
FRAFrance Grenoble, Nantes and Rennes0.00406094See
ARGArgentina La Plata1.00.0040100See
ESPSpain Majorca0.0040407See
TURTurkey pop 20.0040228See
POLPoland pop 30.80.00392907See
IRLIreland South pop 20.003817624See
GBRUnited Kingdom Central0.0038135See
CHNChina Shandong Province Linqu County0.70.0035139See
CHNChina Guangdong Province0.70.0035403See
MEXMexico Sonora, Ciudad Obregón0.0035143See
RUSRussia Moscow Pop 20.60.00312000See
GRCGreece pop 70.003111250See
RUSRussia Northwest pop 20.60.0030346See
IRNIran Royan Cord Blood Bank0.60.003015600See
SRBSerbia Vojvodina0.70.0030400See
ARMArmenia Yerevan0.0030445See
ISRIsrael Jews pop 20.60.003023000See
SAUSaudi Arabia pop 20.0030383See
MKDMacedonia pop 30.0030172See
DEUGermany Essen0.60.0030174See
RUSRussia Northwest0.60.00301011See
INDIndia North Gujarat0.60.0030338See
IRNIran pop 40.0029855See
SWESweden pop 40.50.0026966See
ALBAlbania pop 20.50.0023432See
RUSRussia Moscow0.00202650See
MKDMacedonia pop 40.0020216See
TWNTaiwan Chinese immigrants from Middle China0.0020211See
GRCGreece pop30.40.0020246See
CHNChina Shanghai0.002026266See
RUSRussia Samara Region0.00202500See
MYSMalaysia pop 30.00201445See
RUSRussia Tatars0.0014355See
IRQIraq Erbil0.30.0013372See
CHNChina Shaanxi Province Han0.001010000See
SRBSerbia pop 30.20.00101992See
ENGEngland London Ashkenazi Jews0.0010500See
CHNChina Shandong Province0.30.00107418See
TWNTaiwan Minnan pop 20.00107137See
GRCGreece North0.0010500See
MKDMacedonia MBMDR - Macedonian0.20.00081283See
MEXMexico Campeche Rural0.000047See
MEXMexico Morelos Rural0.000030See
MEXMexico Baja Californa, Mexicali0.0000100See
TTOTrinidad South Asian0.000087See
MEXMexico Nahuas0.000072See
MEXMexico Huasteca Region Teenek0.000055See
PAKPakistan Baloch0.000066See
PAKPakistan Brahui0.0000104See
PAKPakistan Burusho0.000092See
PAKPakistan Kalash0.000069See
PAKPakistan Mixed Pathan0.0000100See
KORSouth Korea pop 10.0000324See
ITAItaly North pop 30.00.000097See
ESPSpain Ibiza0.000088See
ESPSpain Majorcans Jews0.0000103See
ARGArgentina Chiriguano0.00.000054See
ARGArgentina Salta Wichi pop 20.00.000019See
RUSRussia Nenet Mixed0.000055See
RUSRussia Arkhangelsk Pomor0.000063See
RUSRussia Murmansk Saomi Mixed0.000070See
TWNTaiwan Chinese immigrants from South China0.0000172See
USAUSA Caucasian Bethesda0.00.0000307See
JPNJapan Hyogo Osaka and Nagano0.0000195See
CHNChina Harbin Manchu0.0000172See
CHNChina Harbin Korean0.0000201See
BRABrazil Parana Oriental0.00.000033See
CHNChina North Han0.0000105See
TWNTaiwan Chinese immigrants from North China0.0000152See
TWNTaiwan Aborigine0.0000111See
TWNTaiwan Hakka pop 20.0000714See
ISRIsrael Ashkenazi Jews pop 20.0000132See
MYSMalaysia Negeri Sembilan Minangkabau0.000034See
MYSMalaysia Perak Rawa0.000023See
HRVCroatia pop 20.0000100See
FRAFrance Corsica Island0.0000100See
MYSMalaysia pop 20.000062See
THAThailand pop 40.000016807See
BIHBosnia and Herzegovina0.0000134See
RUSRussia South Ural Russian0.00.0000207See
RUSRussia South Ural Bashkir0.00.0000146See
RUSRussia South Ural Tatar0.00.0000135See
RUSRussia Northwest pop 30.00.0000100See
MEXMexico Quintana Roo, Cancun0.000048See
MEXMexico Mexico City West0.000033See
ECUEcuador Amazonia Mixed Ancestry0.000039See
SVNSlovenia pop 30.00.0000130See
GBRUnited Kingdom South West0.0000163See
MEXMexico Oaxaca, Oaxaca city0.0000151See
MEXMexico Mexico City South0.000052See
MEXMexico Mexico City East0.000079See
MEXMexico Jalisco, Tlaquepaque0.000039See
MEXMexico Jalisco, Tlajomulco0.000030See
MEXMexico Guanajuato, Guanajuato city0.000022See
MEXMexico Veracruz, Cordoba0.000056See
MEXMexico Aguascalientes state0.000095See

Frequency data at lower resolution for this allele can be found in links below

Allele  Number of Populations 


* Allele Frequency: Total number of copies of the allele in the population sample (Alleles / 2n) in decimal format.
   Important: This field has been expanded to four decimals to better represent frequencies of large datasets (e.g. where sample size > 1000 individuals)
* Phenotype Frequency: Percentage of individuals who have the allele or gene (Individuals / n).
* Allele Frequencies shown in green were calculated from Phenotype Frequencies assuming Hardy-Weinberg proportions.

¹ IMGT/HLA Database - For more details of the allele.
² Distribution - Graphical distribution of the allele.
³ Haplotype Association - Find HLA haplotypes with this allele.
ª Notes - See notes for ambiguous combinations of alleles.


Allele frequency net database (AFND) 2020 update: gold-standard data classification, open access genotype data and new query tools
Gonzalez-Galarza FF, McCabe A, Santos EJ, Jones J, Takeshita LY, Ortega-Rivera ND, Del Cid-Pavon GM, Ramsbottom K, Ghattaoraya GS, Alfirevic A, Middleton D and Jones AR Nucleic Acid Research 2020, 48:D783-8.
Liverpool, U.K.

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