Allele Frequencies in World Populations

HLA Database » Allele Report

The list below shows all populations in AFND that contains the allele. If an allele has an entry with a lower resolution this will be shown at the end.

Allele: 
   

B*46:01

 
Allele reported 168 time(s) and present in 123 population(s).

Population Phenotype
Frequency (%)
Allele
Frequency
(in_decimals)
Sample
Size
IMGT/HLA¹
Database
Distribution² Haplotype³
Association
Notesª
CHNChina Southwest Dai0.2540124See
CHNChina Guizhou Province Shui0.2360153See
CHNChina Guizhou Province Miao pop 20.229085See
CHNChina Yunnan Province Han0.1980101See
CHNChina Guizhou Province Bouyei0.1910109See
TWNTaiwan pop 20.1820364See
CHNChina Sichuan HIV negative0.176034See
SGPSingapore Thai0.1720100See
TWNTaiwan pop 30.1680212See
CHNChina Yunnan Hani0.1630150See
HKGHong Kong Chinese30.40.1630569See
CHNChina Guangzhou0.1550102See
TWNTaiwan Minnan pop 127.50.1520102See
THAThailand Northeast0.151066See
CHNChina Hubei Han30.00.15023732See
HKGHong Kong Chinese BMDR0.14857595See
CHNChina Yunnan Province Jinuo0.1470109See
SGPSingapore Chinese Han0.145094See
HKGHong Kong Chinese cord blood registry0.14033892See
THAThailand Northeast pop 20.1390400See
CHNChina Marrow Donor Registry0.1380600See
TWNTaiwan Tzu Chi Morrow Donor Registry0.137946682See
TWNTaiwan Han Chinese0.1360504See
TWNTaiwan Hakka27.30.136055See
USAUSA NMDP Chinese0.134399672See
SGPSingapore Chinese23.50.1340149See
CHNChina Guangxi Region Maonan0.1340108See
TWNTaiwan Tzu Chi Cord Blood Bank0.1260710See
MYSMalaysia Peninsular Chinese21.70.1211194See
USAUSA NMDP Vietnamese0.119443540See
CHNChina Canton Han0.1190264See
VNMVietnam Hanoi Kinh pop 20.1150170See
CHNChina South Han0.1150284See
MYSMalaysia Kelantan21.40.107028See
DEUGermany DKMS - China minority0.10341282See
CHNChina Guangdong Province Meizhou Han0.1000100See
SGPSingapore SGVP Chinese CHS0.097096See
CHNChina Beijing Shijiazhuang Tianjian Han0.0960618See
CHNChina Guangzhou Han0.0940106See
THAThailand0.0920142See
CHNChina Yunnan Province Nu0.0900107See
CHNChina Jiangsu Han0.08903238See
THAThailand pop 30.082049See
TWNTaiwan Pazeh14.50.082055See
CHNChina Jiangsu Province Han0.0768334See
CHNChina Yunnan Province Lisu0.0720111See
CHNChina Beijing0.068067See
CHNChina Shanxi HIV negative0.068022See
USAUSA Asian0.0660358See
CHNChina Han HIV negative0.063072See
CHNChina Henan HIV negative0.063016See
USAUSA Asian pop 20.06111772See
JPNJapan pop 50.0610117See
CHNChina Qinghai Province Hui0.0590110See
CHNChina North Han0.0570105See
MYSMalaysia Champa10.30.052029See
USAUSA NMDP Korean0.050777584See
JPNJapan pop 30.05001018See
JPNJapan pop 160.047718604See
KORSouth Korea pop 100.04744128See
KORSouth Korea pop 30.0440485See
TWNTaiwan Tzu Chi Morrow Donor Registry Aborigine0.0429233See
MYSMalaysia Jelebu Temuan0.042025See
USAUSA NMDP Japanese0.041024582See
TWNTaiwan Siraya7.80.039051See
JPNJapan Central0.0360371See
USAUSA NMDP Southeast Asian0.034127978See
CHNChina Uyghur HIV negative0.026019See
MYSMalaysia Peninsular Malay4.90.0252951See
USAUSA NMDP Filipino0.025150614See
MYSMalaysia Sarawak Bau Bidayuh0.020025See
MYSMalaysia Perak Grik Jehai0.020025See
SGPSingapore Javaneses0.020051See
CHNChina Inner Mongolia Region0.0200102See
TWNTaiwan Thao3.30.017030See
SGPSingapore Riau Malay0.0150132See
RUSRussia Tuva pop 20.0140169See
USAUSA San Diego2.90.0140496See
CHNChina Tibet Region Tibetan0.0130158See
SGPSingapore SGVP Malay MAS0.012089See
USAUSA NMDP Hawaiian or other Pacific Islander0.010411499See
USAUSA Hawaii Okinawa0.0100106See
JPNJapan Hokkaido Ainu0.010050See
CHNChina Yunnan Bulang0.0090116See
CUBCuba Caucasian1.40.007070See
INDIndia Northeast UCBB1.40.0068296See
IRNIran Tabriz Azeris0.005297See
TWNTaiwan Atayal0.90.0050106See
RUSRussia Bering Island Aleuts0.0048104See
CHESwitzerland Aargau-Solothurn0.00401838See
CHNChina Yunnan Province Wa0.0040119See
DEUGermany DKMS - Turkey minority0.00244856See
MEXMexico Mexico City Tlalpan0.30.0015330See
PANPanama0.0011462See
USAUSA NMDP South Asian Indian0.0010185391See
CHESwitzerland Graubunden0.0010759See
USAUSA Eastern European0.0010558See
ROMRomania0.30.0010348See
DEUGermany DKMS - Portugal minority0.00091176See
DEUGermany DKMS - Romania minority0.00081234See
USAUSA NMDP Caribean Black0.000633328See
CHESwitzerland Bern0.00063545See
CHESwitzerland Lausanne0.0006993See
ISRIsrael USSR Jews0.000645681See
CZECzech Republic NMDR0.00045099See
DEUGermany pop 80.000439689See
POLPoland DKMS0.000520653See
USAUSA NMDP Middle Eastern or North Coast of Africa0.000370890See
DEUGermany DKMS - Austria minority0.00031698See
USAUSA NMDP Hispanic South or Central American0.0002146714See
USAUSA NMDP Mexican or Chicano0.0002261235See
DEUGermany DKMS - German donors0.00023456066See
BELBelgium0.00.000231412See
USAUSA NMDP Caribean Hispanic0.0002115374See
ISRIsrael Kavkazi Jews0.00022840See
USAUSA NMDP North American Amerindian0.000135791See
DEUGermany pop 60.00028862See
INDIndia West UCBB0.00.00015829See
USAUSA NMDP European Caucasian0.00011242890See
USAUSA NMDP African American pop 20.0001416581See
USAUSA NMDP African0.000128557See
INDIndia South UCBB0.00.000011446See
ISRIsrael USA Jews0.00006058See
NLDNetherlands Leiden0.00001305See
CHESwitzerland Basel0.00001888See
CHESwitzerland Geneva pop 20.00001267See
CHESwitzerland Luzern0.00001553See
CHESwitzerland St Gallen0.00002113See
CHESwitzerland Sion0.0000832See
CHESwitzerland Zurich0.00004875See
CHESwitzerland Lugano0.00001169See
USAUSA Caucasian Bethesda0.00.0000307See
USAUSA African American Bethesda0.00.0000187See
MARMorocco Nador Metalsa pop 20.000073See
MARMorocco Settat Chaouya0.00.000098See
USAUSA Caucasian pop 20.0000265See
USAUSA African American0.0000252See
USAUSA Hispanic0.0000234See
USAUSA North American Native0.0000187See
BGRBulgaria0.000055See
USAUSA San Antonio Caucasian0.0000222See
USAUSA South Texas Hispanic0.0000194See
USAUSA Alaska Yupik0.0000252See
CZECzech Republic0.0000106See
TWNTaiwan Taroko0.00.000055See
TWNTaiwan Saisiat0.00.000051See
TWNTaiwan Bunun0.00.0000101See
TWNTaiwan Tsou0.00.000051See
TWNTaiwan Rukai0.00.000050See
TWNTaiwan Paiwan0.00.000051See
TWNTaiwan Ami0.00.000098See
TWNTaiwan Puyuma0.00.000050See
TWNTaiwan Tao0.00.000050See
MEXMexico Mestizo0.00.000041See
OMNOman0.00.0000118See
ZAFSouth Africa Natal Zulu0.00.0000100See
NIRIreland Northern0.00.00001000See
PHLPhilippines Ivatan0.00.000050See
BRABrazil Belo Horizonte Caucasian0.00.000095See
CUBCuba Mixed Race0.00.000042See
USAUSA African American pop 40.00002411See
USAUSA Hispanic pop 20.00001999See
FRAFrance Grenoble, Nantes and Rennes0.00006094See
BFABurkina Faso Fulani0.000049See
BFABurkina Faso Mossi0.000053See
BFABurkina Faso Rimaibe0.000047See
USAUSA Philadelphia Caucasian0.00.0000141See
SGPSingapore SGVP. Indian INS0.000086See

Frequency data at lower resolution for this allele can be found in links below


Allele  Number of Populations 

Notes:

* Allele Frequency: Total number of copies of the allele in the population sample (Alleles / 2n) in decimal format.
   Important: This field has been expanded to four decimals to better represent frequencies of large datasets (e.g. where sample size > 1000 individuals)
* Phenotype Frequency: Percentage of individuals who have the allele or gene (Individuals / n).
* Allele Frequencies shown in green were calculated from Phenotype Frequencies assuming Hardy-Weinberg proportions.

¹ IMGT/HLA Database - For more details of the allele.
² Distribution - Graphical distribution of the allele.
³ Haplotype Association - Find HLA haplotypes with this allele.
ª Notes - See notes for ambiguous combinations of alleles.


   

Allele frequency net database (AFND) 2020 update: gold-standard data classification, open access genotype data and new query tools
Gonzalez-Galarza FF, McCabe A, Santos EJ, Jones J, Takeshita LY, Ortega-Rivera ND, Del Cid-Pavon GM, Ramsbottom K, Ghattaoraya GS, Alfirevic A, Middleton D and Jones AR Nucleic Acid Research 2020, 48:D783-8.
Liverpool, U.K.

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