Allele Frequencies in World Populations

HLA Database » Allele Report

The list below shows all populations in AFND that contains the allele. If an allele has an entry with a lower resolution this will be shown at the end.



Allele reported 327 time(s) and present in 207 population(s).

Population Phenotype
Frequency (%)
Distribution² Haplotype³
SDNSudan South Nuba17.40.091146See
HRVCroatia pop 20.0500100See
RUSRussia Murmansk Saomi Mixed0.040070See
CMRCameroon Bamileke 20.029035See
SAUSaudi Arabia5.60.028418See
CHNChina Yunnan Province Han pop 20.0260129See
MARMorocco pop 20.0230110See
MEXMexico Tabasco, Villahermosa0.018382See
GEOGeorgia Kurds0.018030See
MEXMexico Jalisco, Tlajomulco0.016730See
GAZGaza Palestinians0.0150165See
BRABrazil Pernambuco Mixed0.0150101See
CHNChina Shandong Province Linqu County2.90.0146139See
CMRCameroon Ewondo0.013038See
ARGArgentina Cuyo Region2.30.0120420See
GRCGreece pop32.40.0120246See
RUSRussia Chuvash0.012082See
MKDMacedonia MBMDR - Albanian2.30.0117128See
VENVenezuela Colonia Tovar0.011686See
TURTurkey pop 50.0110142See
VENVenezuela Caracas Mestizo0.010050See
RUSRussia Arkhangelsk Pomor0.010063See
MEXMexico Baja Californa, Mexicali0.0100100See
MARMorocco Casablanca0.0090100See
MEXMexico Veracruz, Orizaba0.008360See
HRVCroatia pop 31.70.0083120See
ITAItaly pop 61.60.0082184See
ALBAlbania pop 21.60.0081432See
ESPSpain Murcia0.0080173See
PAKPakistan Baloch0.008066See
MEXMexico Nayarit Rural0.007864See
ROMRomania pop 31.40.00721469See
PERPeru Arequipa Mestizo1.40.0070168See
PRTMadeira pop 30.0070538See
MEXMexico Tapachula, Chiapas Mestizo Population1.40.007072See
MEXMexico Nuevo Leon, Monterrey city0.0066226See
MEXMexico Durango, Durango city0.0065153See
SWESweden Uppsala1.30.0065300See
MNGMongolia Tarialan Khoton0.006085See
BRABrazil Parana Afro Brazilian1.30.006077See
ITAItaly North Pavia0.006081See
ESPSpain Majorca0.0060407See
PRTPortugal Guarda0.0060797See
CHNChina Yunnan Province Naxi0.0060118See
RUSRussia Samara Region0.00602500See
ITAItaly Lombardy1.20.0060674See
ARMArmenia living in Iran0.006085See
ENGEngland Liverpool1.10.00551343See
PRTPortugal North pop 20.00521801See
SRBSerbia pop 30.90.00501992See
ARMArmenia Lori0.0050102See
FRAFrance Rennes pop 30.0050200See
ITAItaly North Pavia pop 20.90.00502416See
PRTPortugal Braga0.00501971See
FRAFrance Reims0.0050102See
VENVenezuela Valencia and Maracaibo Caracus Mixed0.005096See
GBRUnited Kingdom pop 20.0050101See
PRTPortugal Leiria0.00501847See
PRTPortugal Evora0.0050737See
PAKPakistan Burusho0.005092See
MNGMongolia Khalkha0.0050200See
PRTPortugal South pop 20.00501021See
BRABrazil Parana Cafuzo0.90.0050319See
CHNChina Harbin Korean0.0050201See
GRCGreece pop 70.004811250See
MEXMexico Zacatecas, Fresnillo0.0048103See
SWESweden pop 40.90.0047966See
ENGEngland Sheffield0.90.00454755See
ENGEngland Lancaster0.90.0045545See
INDIndia North Gujarat0.90.0044338See
MEXMexico Jalisco Rural0.0043585See
FRAFrance Lyon0.80.00424813See
FRAFrance Bordeaux0.80.0042990See
BIHBosnia and Herzegovina pop 20.80.0042120See
FRAFrance Marseille0.80.00411000See
MEXMexico Chiapas Rural0.0041121See
ENGEngland Manchester0.80.00401640See
USAUSA OPTN Hispanic0.00401580See
PRTPortugal Faro0.00401242See
PRTPortugal Lisbon0.004017420See
PRTPortugal Portalegre0.00401254See
PRTPortugal Beja0.0040699See
PRTPortugal Setubal0.00405268See
WALWales pop 20.70.004039979See
RUSRussia Moscow0.00402650See
GRCGreece North0.0040500See
FRAFrance Southeast0.80.0040130See
ITAItaly North Pavia pop 30.0039685See
GTMGuatemala, Guatemala City Mixed Ancestry0.80.0039127See
MKDMacedonia MBMDR - Macedonian0.80.00391283See
GBRUnited Kingdom Central0.0038135See
MEXMexico Mestizo pop 40.0037269See
MEXMexico Tabasco Rural0.0035142See
BRABrazil REDOME Santa Catarina0.0033106673See
CHLChile Santiago0.0033920See
GBRUnited Kingdom South West0.0032163See
BRABrazil REDOME Sergipe0.00317321See
MEXMexico Durango Rural0.0031326See
ARMArmenia living in Lebanon0.0030368See
SAUSaudi Arabia pop 40.60.0030499See
POLPoland pop 30.60.00302907See
SVKSlovakia pop 20.00304234See
COLColombia Barranquilla0.0030188See
MEXMexico Jalisco, Zapopan0.0030168See
ARGArgentina Buenos Aires0.60.0030466See
ITAItaly South Campania Region0.60.00301089See
PRTPortugal Center pop 20.0030562See
BRABrazil Parana Mixed race0.50.0030186See
NORNorway pop 20.0030576See
PRTPortugal Santarem0.00303865See
PRTPortugal Castelo Branco0.0030327See
USAUSA OPTN Caucasian0.00308525See
ENGEngland Leeds0.60.00305024See
ENGEngland Newcastle0.60.00302739See
FRAFrance Grenoble, Nantes and Rennes0.00306094See
MEXMexico Jalisco, Guadalajara city0.00291189See
BRABrazil REDOME Alagoas0.002925349See
ESPSpain, Castilla y Leon, Northwest,0.30.00291743See
MEXMexico Veracruz Rural0.0028539See
BRABrazil REDOME Bahia0.002847399See
BRABrazil REDOME Paraiba0.002743868See
NORNorway ethnic Norwegians0.50.00274510See
IRQIraq Erbil0.50.0027372See
BRABrazil Parana Japanese1.00.0026192See
MEXMexico Yucatan, Merida0.0026192See
BRABrazil REDOME Pernambuco0.002692332See
ENGEngland North West Mixed pop 20.50.0026379See
FRAFrance Rennes pop 40.50.00261000See
RUSRussia Moscow Pop 20.50.00252000See
MEXMexico Sonora Rural0.0025197See
CHNChina Guangdong Province0.50.0025403See
BRABrazil REDOME Parana0.0024341639See
BRABrazil REDOME Espirito Santo0.002488485See
MEXMexico Tlaxcala Rural0.0024830See
BRABrazil Paraná Caucasian0.50.0023641See
MEXMexico Coahuila Rural0.0023216See
BRABrazil REDOME Acre0.0023859See
BRABrazil REDOME Roraima0.00234140See
MEXMexico Nuevo Leon Rural0.0023439See
BRABrazil REDOME Sao Paulo0.0022800809See
BRABrazil REDOME Mato Grosso do Sul0.002295667See
BRABrazil REDOME Tocantins0.002220692See
BRABrazil REDOME Rio Grande do Norte0.002246603See
BRABrazil REDOME Rio Grande do Sul0.0022241329See
ECUEcuador Coast Mixed Ancestry0.0021238See
BRABrazil REDOME Federal District0.002129549See
BRABrazil REDOME Rio de Janeiro0.0021139322See
IRLIreland South pop 20.002117624See
FRAFrance Grenoble0.40.00211000See
BRABrazil South East Cord Blood0.002111409See
BRABrazil Rio Grande do Norte Mestizo0.002012973See
BRABrazil REDOME Ceara0.0020101217See
KURIraq Kurdistan Region0.50.0020209See
BRABrazil Sao Paulo Bauru Mixed0.00203542See
BRABrazil Rio Grande do Sul Black0.0020248See
BRABrazil Rio Grande do Sul Caucasoid0.00204428See
ARMArmenia living in Karabakh0.0020445See
MEXMexico Mexico City North0.0020751See
BRABrazil Minas Gerais State Mixed0.40.00201000See
PRTPortugal Aveiro0.00205933See
PRTPortugal Coimbra0.00205057See
PRTPortugal Porto0.00207937See
PRTPortugal Viana do Castelo0.0020706See
PRTPortugal Vila Real0.00201167See
IRNIran Royan Cord Blood Bank0.40.002015600See
RUSRussia South Ural Russian0.50.0020207See
BRABrazil Parana Caucasian0.40.00202775See
ARGArgentina Buenos Aires pop 20.40.00201216See
AUSAustralia West Caucasian0.30.0020891See
BRABrazil REDOME Mato Grosso0.001934649See
BRABrazil REDOME Amazonas0.001924129See
ESPSpain Sevilla0.40.0018278See
BRABrazil REDOME Goias0.001888574See
BRABrazil REDOME Minas Gerais0.0018211275See
BRABrazil Para State0.20.00185000See
BRABrazil REDOME Rondonia0.001754396See
BRABrazil REDOME Piaui0.001546140See
BRABrazil REDOME Para0.001572637See
BRABrazil REDOME Amapa0.001517864See
RUSRussia Northwest0.30.00151011See
RUSRussia Tatars0.0014355See
BRABrazil REDOME Maranhao0.001310180See
IRNIran pop 40.0012855See
BRABrazil Para Cord Blood Unit0.20.0012841See
BRABrazil Rio Grande do Sul Mixed0.0010324See
BRABrazil Piaui Mixed0.001021943See
SRBSerbia Vojvodina0.20.0010400See
ISRIsrael Jews pop 20.30.001023000See
RUSRussia Northwest pop 20.10.0010346See
PRTPortugal Viseu0.00102915See
KORSouth Korea pop 80.00107096See
USAUSA OPTN African American0.00101510See
SAUSaudi Arabia pop 20.0010383See
MEXMexico Puebla, Puebla city0.00051994See
ECUEcuador Mixed Ancestry0.00041173See
MEXMexico Quintana Roo, Cancun0.000048See
MEXMexico Mexico City West0.000033See
ECUEcuador Amazonia Mixed Ancestry0.000039See
ECUEcuador Andes Mixed Ancestry0.0000824See
MEXMexico Tlaxcala, Tlaxcala city0.0000181See
MEXMexico Mexico City South0.000052See
MEXMexico Campeche, Campeche city0.000034See
MEXMexico Chiapas, Tuxtla Gutierrez0.000052See
MEXMexico Morelos, Cuernavaca0.000082See
MEXMexico Oaxaca, Oaxaca city0.0000151See
MEXMexico Guerrero state0.0000144See
MEXMexico Mexico City East0.000079See
MEXMexico Mexico City Center0.0000152See
MEXMexico Hidalgo, Pachuca0.000041See
MEXMexico Veracruz, Xalapa0.0000187See
MEXMexico Veracruz, Veracruz city0.0000171See
MEXMexico Veracruz, Poza Rica0.000045See
MEXMexico Veracruz, Cordoba0.000056See
MEXMexico Queretaro Rural0.000043See
MEXMexico Tamaulipas Rural0.0000125See
MEXMexico San Luis Potosi Rural0.000087See
MEXMexico Michoacan Rural0.0000348See
MEXMexico Guanajuato Rural0.0000162See
MEXMexico Colima Rural0.000043See
MEXMexico Sinaloa Rural0.0000183See
MEXMexico Chihuahua Rural0.0000236See
MEXMexico Baja California Rural0.000050See
MEXMexico Chihuahua, Ciudad Juarez0.0000106See
MEXMexico Chihuahua Chihuahua City0.0000119See
MEXMexico Sinaloa, Culiacán0.0000103See
MEXMexico Sonora, Hermosillo0.000099See
MEXMexico Sonora, Ciudad Obregón0.0000143See
MEXMexico Baja California, La Paz0.000075See
MEXMexico Nayarit, Tepic0.000097See
MEXMexico Jalisco, Tonala0.000035See
MEXMexico Jalisco, Tlaquepaque0.000039See
MEXMexico Zacatecas, Zacatecas city0.000084See
MEXMexico Coahuila, Torreon0.0000396See
MEXMexico Coahuila, Saltillo0.000072See
MEXMexico Colima, Colima city0.000061See
MEXMexico Guanajuato, Leon0.000078See
MEXMexico Guanajuato, Guanajuato city0.000022See
MEXMexico Michoacan, Morelia0.0000150See
MEXMexico Veracruz, Coatzacoalcos0.000055See
MEXMexico San Luis Potosi, San Luis Potosi city0.000030See
MEXMexico Tamaulipas, Ciudad Victoria0.000023See
MEXMexico Queretaro, Queretaro city0.000045See
MEXMexico Aguascalientes state0.000095See
ARGArgentina Corrientes0.00.0000155See
CMRCameroon Uldeme0.000035See
CMRCameroon Podokwo0.000043See
RUSRussia Northwest pop 30.00.0000100See
SVNSlovenia pop 30.00.0000130See
GBRUnited Kingdom East0.0000163See
GBRUnited Kingdom North0.0000330See
GBRUnited Kingdom Orkney0.000088See
PRTPortugal Bragança0.0000301See
CHNChina Shandong Province0.10.00007418See
MYSMalaysia pop 20.000062See
CHNChina Jiangsu Province0.000020248See
USAUSA OPTN Asian0.0000261See
CHNChina Shanghai0.000126266See
NORNorway Sami0.0000200See
RUSRussia South Ural Bashkir0.00.0000146See
RUSRussia South Ural Tatar0.00.0000135See
MEXMexico Mexico City Mestizo0.0000121See
MEXMexico Puebla Mestizo0.000099See
MEXMexico Sinaloa Mestizo0.000056See
TZATanzania Dodoma Kongwa0.0000212See
BIHBosnia and Herzegovina0.0000134See
CHNChina Shaanxi Province Han0.000010000See
THAThailand pop 40.000016807See
AREUnited Arab Emirates pop 20.00.0000373See
PAKPakistan Karachi Parsi0.000091See
BRABrazil Parana Oriental0.00.000033See
CHNChina North Han0.0000105See
MKDMacedonia pop 40.0000216See
TWNTaiwan Minnan pop 20.00007137See
TWNTaiwan Chinese immigrants from South China0.0000172See
TWNTaiwan Chinese immigrants from Middle China0.0000211See
TWNTaiwan Chinese immigrants from North China0.0000152See
TWNTaiwan Aborigine0.0000111See
TWNTaiwan Hakka pop 20.0000714See
MNGMongolia Ulaanbaatar Khalkha0.000041See
JPNJapan Hyogo Osaka and Nagano0.0000195See
MNGMongolia Khalkha pop 20.0000202See
CHNChina Harbin Manchu0.0000172See
KORSouth Korea pop 10.0000324See
ITAItaly Rome0.00.0000100See
ITAItaly North pop 30.00.000097See
BRABrazil Sao Paulo Mixed0.00.0000239See
ESPSpain Minorca0.000094See
ESPSpain Ibiza0.000088See
ESPSpain Majorcans Jews0.0000103See
ARGArgentina Chiriguano0.00.000054See
ARGArgentina Salta Wichi pop 20.00.000019See
PRTPortugal North0.000046See
ARGArgentina La Plata0.00.0000100See
RUSRussia Nenet Mixed0.000055See
ZAFSouth Africa Natal Zulu0.00.0000100See
MNGMongolia Oold0.0000104See
MNGMongolia Tsaatan0.0000144See
USAUSA Caucasian Bethesda0.00.0000307See
USAUSA African American Bethesda0.00.0000187See
PAKPakistan Kalash0.000069See
PAKPakistan Mixed Pathan0.0000100See
PAKPakistan Mixed Sindhi0.0000101See
PAKPakistan Brahui0.0000104See
MEXMexico Baja California, Tijuana0.000025See
MEXMexico Campeche Rural0.000047See
MEXMexico Yucatan Rural0.0000132See
MEXMexico Quintana Roo Rural0.000050See
MEXMexico Zacatecas Rural0.0000266See
MEXMexico Hidalgo Rural0.000081See
MEXMexico Mexico City Metropolitan Area Rural0.0000150See
MEXMexico Puebla Rural0.0000833See
MEXMexico Oaxaca Rural0.0000485See
MEXMexico Morelos Rural0.000030See

Frequency data at lower resolution for this allele can be found in links below

Allele  Number of Populations 


* Allele Frequency: Total number of copies of the allele in the population sample (Alleles / 2n) in decimal format.
   Important: This field has been expanded to four decimals to better represent frequencies of large datasets (e.g. where sample size > 1000 individuals)
* Phenotype Frequency: Percentage of individuals who have the allele or gene (Individuals / n).
* Allele Frequencies shown in green were calculated from Phenotype Frequencies assuming Hardy-Weinberg proportions.

¹ IMGT/HLA Database - For more details of the allele.
² Distribution - Graphical distribution of the allele.
³ Haplotype Association - Find HLA haplotypes with this allele.
ª Notes - See notes for ambiguous combinations of alleles.


Allele frequency net database (AFND) 2020 update: gold-standard data classification, open access genotype data and new query tools
Gonzalez-Galarza FF, McCabe A, Santos EJ, Jones J, Takeshita LY, Ortega-Rivera ND, Del Cid-Pavon GM, Ramsbottom K, Ghattaoraya GS, Alfirevic A, Middleton D and Jones AR Nucleic Acid Research 2020, 48:D783-8.
Liverpool, U.K.

Valid XHTML 1.0 Transitional