Allele Frequencies in World Populations

HLA Database » Allele Report

The list below shows all populations in AFND that contains the allele. If an allele has an entry with a lower resolution this will be shown at the end.



Allele reported 392 time(s) and present in 348 population(s).

Population Phenotype
Frequency (%)
Distribution² Haplotype³
RUSRussia North Ossetian29.90.1575127See
CMRCameroon Bamileke 20.143035See
DZAAlgeria pop 219.00.1000106See
VENVenezuela Zulia San Jose de Heras Mixed0.100020See
MEXMexico Nahuas0.097072See
SDNSudan Khartoum0.086798See
CUBCuba Mixed0.085078See
ESPSpain Minorca0.081094See
PRTPortugal North0.076046See
ARMArmenia Syunik0.0730117See
ARMArmenia living in Karabakh0.0690445See
ARMArmenia living in USA0.0690233See
GAZGaza Palestinians0.0690165See
MEXMexico Guanajuato, Guanajuato city0.068222See
ARMArmenia Yerevan0.0680445See
IRQIraq Arabs11.40.0671149See
ESPSpain Majorca and Minorca0.067090See
TURTurkey pop 20.0660228See
ARMArmenia Shirak0.066076See
ARMArmenia living in Iran0.065085See
ESPSpain Majorca0.0650407See
PRTPortugal Guarda0.0610797See
MYSMalaysia Negeri Sembilan Minangkabau0.060034See
ITAItaly East Sicily10.00.060050See
VENVenezuela Caracas Mestizo0.060050See
ARMArmenia Lori0.0590102See
PRTMadeira pop 30.0590538See
MEXMexico Campeche, Campeche city0.058834See
CMRCameroon Podokwo0.058043See
ARMArmenia Ghegharkunik0.0580242See
MEXMexico Guanajuato, Leon0.057778See
ESPSpain Sevilla10.80.0558278See
ITAItaly Rome11.00.0550100See
ESPSpain Majorcans Jews0.0550103See
ESPSpain Arratia Valley Basque0.053083See
ITAItaly South Campania Region10.00.05131089See
TTOTrinidad African0.050067See
ITAItaly pop 69.80.0489184See
PRTPortugal Bragança0.0480301See
ARMArmenia living in Lebanon0.0480368See
MEXMexico Coahuila, Saltillo0.047972See
CZECzech Republic Kurd9.50.047374See
ITAItaly North Pavia pop 30.0465685See
PRTMadeira pop 20.0460173See
BRABrazil Parana Afro Brazilian9.10.045077See
INDIndia Kerala Kanikkar0.045022See
ISRIsrael Moroccan Jews0.0450113See
ESPSpain Murcia0.0440173See
PRTPortugal South pop 20.04301021See
CMRCameroon Uldeme0.043035See
PRTPortugal Center pop 20.0420562See
ESPSpain, Castilla y Leon, Northwest,7.80.04191743See
MEXMexico Veracruz, Orizaba0.041760See
BRABrazil Curitiba-Parana Mixed0.0412264See
MEXMexico Mexico City Mestizo0.0410121See
PRTPortugal Beja0.0410699See
PRTPortugal Braga0.04101971See
PRTPortugal Leiria0.04101847See
PRTPortugal Portalegre0.04101254See
MARMorocco Casablanca0.0410100See
ESPSpain North8.00.0408156See
MEXMexico San Luis Potosi Rural0.040287See
CUBCuba Mixed pop 20.0400189See
ESPSpain Ibiza0.040088See
PRTPortugal Faro0.04001242See
MYSMalaysia Perak Rawa0.040023See
MKDMacedonia MBMDR - Macedonian Muslims7.90.039576See
BRABrazil Rio Grande do Sul Black0.0380248See
ESPSpain Pas Valley0.038088See
FRAFrance Corsica Island0.0380100See
ITAItaly North Pavia pop 27.30.03702416See
PRTPortugal Porto0.03707937See
PRTPortugal Vila Real0.03701167See
BRABrazil Paraná Caucasian7.20.0367641See
PRTPortugal Setubal0.03605268See
SENSenegal Dakar7.10.0360112See
MEXMexico Durango, Durango city0.0355153See
PRTAzores Terceira Island0.0350130See
BRABrazil Pernambuco Mixed0.0350101See
TURTurkey pop 50.0350142See
PRTPortugal Viseu0.03502915See
PRTPortugal Lisbon0.035017420See
PRTPortugal Evora0.0350737See
GRCGreece pop 70.034811250See
MEXMexico Guanajuato Rural0.0337162See
MEXMexico Jalisco, Tlajomulco0.033330See
MEXMexico Baja California, La Paz0.033375See
MEXMexico San Luis Potosi, San Luis Potosi city0.033330See
BRABrazil REDOME Minas Gerais0.0333211275See
KURIraq Kurdistan Region6.70.0330209See
ITAItaly Lombardy6.70.0330674See
RUSRussia South Ural Tatar6.70.0330135See
PRTPortugal Aveiro0.03305933See
SAUSaudi Arabia pop 20.0330383See
BRABrazil South East Cord Blood0.033011409See
PRTPortugal North pop 20.03241801See
BRABrazil REDOME Goias0.032188574See
MEXMexico Campeche Rural0.031947See
BRABrazil REDOME Rio de Janeiro0.0310139322See
IRNIran pop 10.031064See
BRABrazil Minas Gerais State Mixed6.10.03101000See
GRCGreece North0.0310500See
MEXMexico Hidalgo Rural0.030981See
IRNIran pop 40.0304855See
BRABrazil REDOME Tocantins0.030320692See
BRABrazil REDOME Federal District0.030129549See
MEXMexico Michoacan Rural0.0301348See
PRTPortugal Coimbra0.03005057See
RUSRussia Chuvash0.030082See
FRAFrance Rennes pop 30.0300200See
ITAItaly Sardinia pop30.0300100See
MEXMexico Mexico City West0.029933See
MEXMexico Yucatan Rural0.0299132See
MEXMexico Zacatecas, Zacatecas city0.029884See
RUSRussia Tatars0.0295355See
SRBSerbia pop 35.90.02941992See
MEXMexico Mexico City Center0.0292152See
BRABrazil REDOME Sao Paulo0.0290800809See
PRTPortugal Santarem0.02903865See
TZATanzania Dodoma Kongwa0.0290212See
USAUSA OPTN African American0.02901510See
FRAFrance Grenoble5.80.02881000See
MEXMexico Mexico City South0.028852See
SDNSudan Central Shaigiya Mixed5.60.028436See
BRABrazil REDOME Bahia0.028347399See
FRAFrance Marseille5.60.02821000See
BRABrazil REDOME Rio Grande do Norte0.028146603See
BRABrazil Sao Paulo Bauru Mixed0.02803542See
BRABrazil Rio Grande do Norte Mestizo0.028012973See
BRABrazil REDOME Alagoas0.027825349See
BRABrazil REDOME Espirito Santo0.027488485See
BRABrazil REDOME Sergipe0.02717321See
BRABrazil REDOME Piaui0.027046140See
BRABrazil Rio Grande do Sul Caucasoid0.02704428See
BRABrazil Rio Grande do Sul Mixed0.0270324See
RUSRussia, South Ural, Chelyabinsk region, Nagaybaks5.40.0270112See
MARMorocco pop 20.0270110See
BRABrazil South Ribeirao Preto0.0270184See
ARGArgentina Cuyo Region5.40.0270420See
GRCGreece Crete0.0270135See
FRAFrance Southeast5.40.0270130See
FRAFrance Bordeaux5.30.0265990See
BRABrazil REDOME Pernambuco0.026592332See
BRABrazil REDOME Mato Grosso do Sul0.026595667See
BRABrazil REDOME Maranhao0.026410180See
BIHBosnia and Herzegovina0.0261134See
ARGArgentina Corrientes5.20.0260155See
IRNIran Royan Cord Blood Bank5.10.026015600See
BRABrazil REDOME Parana0.0260341639See
BRABrazil REDOME Rondonia0.026054396See
VENVenezuela Valencia and Maracaibo Caracus Mixed0.026096See
ARGArgentina Buenos Aires pop 25.10.02601216See
ISRIsrael Jews pop 25.20.026023000See
MEXMexico Jalisco, Guadalajara city0.02601189See
BRABrazil REDOME Paraiba0.025843868See
BRABrazil REDOME Ceara0.0257101217See
FRAFrance Lyon5.10.02574813See
BRABrazil REDOME Santa Catarina0.0256106673See
MEXMexico Jalisco, Tlaquepaque0.025639See
BRABrazil REDOME Mato Grosso0.025534649See
CHLChile Santiago0.0250920See
BRABrazil Piaui Mixed0.025021943See
BIHBosnia and Herzegovina pop 24.20.0250120See
FRAFrance Reims0.0250102See
SVKSlovakia pop 20.02494234See
MEXMexico Colima, Colima city0.024661See
MEXMexico Hidalgo, Pachuca0.024441See
MEXMexico Zacatecas Rural0.0242266See
MEXMexico Mestizo pop 40.0242269See
BRABrazil REDOME Rio Grande do Sul0.0242241329See
RUSRussia South Ural Bashkir4.80.0240146See
PRTPortugal Castelo Branco0.0240327See
FRAFrance Grenoble, Nantes and Rennes0.02406094See
ESPSpain North Cantabria0.024083See
COLColombia San Basilio de Palenque0.024042See
BRABrazil Para State4.80.02395000See
MEXMexico Coahuila, Torreon0.0238396See
BRABrazil REDOME Para0.023472637See
BRABrazil REDOME Amapa0.023317864See
ECUEcuador Coast Mixed Ancestry0.0231238See
GBRUnited Kingdom North0.0230330See
SRBSerbia Vojvodina4.50.0230400See
RUSRussia Samara Region0.02302500See
BRABrazil Parana Cafuzo4.70.0230319See
FRAFrance Rennes pop 44.60.02281000See
MEXMexico Sonora Rural0.0228197See
MEXMexico Colima Rural0.022743See
MKDMacedonia MBMDR - Macedonian4.50.02261283See
MEXMexico Jalisco Rural0.0222585See
MEXMexico Sinaloa Rural0.0219183See
BOLBolivia Quechua0.021769See
IRQIraq Erbil4.30.0215372See
BRABrazil REDOME Acre0.0215859See
MEXMexico Tabasco Rural0.0211142See
BRABrazil Parana Caucasian4.20.02102775See
INDIndia Kerala Hindu Ezhava0.021024See
USAUSA OPTN Hispanic0.02101580See
USAUSA African American Bethesda4.20.0210187See
BRABrazil REDOME Amazonas0.020924129See
COLColombia Wayu from Guajira Peninsula0.020848See
MEXMexico Quintana Roo, Cancun0.020848See
MEXMexico Chiapas Rural0.0207121See
GRCGreece pop34.10.0207246See
BRABrazil Para Cord Blood Unit4.00.0202841See
MEXMexico Baja California Rural0.020050See
ROMRomania pop 20.02006936See
HRVCroatia pop 20.0200100See
BRABrazil Sao Paulo Mixed0.40.0200239See
SVNSlovenia pop 33.90.0200130See
PRTPortugal Viana do Castelo0.0200706See
MEXMexico Durango Rural0.0199326See
MEXMexico Michoacan, Morelia0.0199150See
BRABrazil REDOME Roraima0.01964140See
ARGArgentina La Plata4.00.0190100See
MKDMacedonia pop 40.0190216See
ESPSpain North Cabuerniga0.019095See
USAUSA Caucasian Bethesda3.10.0190307See
MEXMexico Zacatecas, Fresnillo0.0190103See
MEXMexico Chiapas, Tuxtla Gutierrez0.018952See
MEXMexico Morelos, Cuernavaca0.018382See
MEXMexico Puebla Rural0.0180833See
ARGArgentina Buenos Aires3.60.0180466See
GEOGeorgia Kurds0.018030See
MEXMexico Veracruz Rural0.0176539See
MEXMexico Sonora, Ciudad Obregón0.0175143See
MEXMexico Oaxaca Rural0.0175485See
ENGEngland North West Mixed pop 23.40.0172379See
ROMRomania pop 33.40.01711469See
RUSRussia Moscow0.01702650See
NORNorway pop 20.0170576See
ENGEngland London Ashkenazi Jews0.0170500See
ALBAlbania pop 23.00.0162432See
ISRIsrael Ashkenazi Jews pop 20.0160132See
MEXMexico Mexico City Mestizo pop 30.0160256See
MEXMexico Tamaulipas Rural0.0159125See
MEXMexico Nuevo Leon Rural0.0159439See
ECUEcuador Mixed Ancestry0.01581173See
RUSRussia Moscow Pop 23.20.01572000See
MKDMacedonia MBMDR - Albanian3.10.0156128See
MEXMexico Nayarit Rural0.015664See
ENGEngland Liverpool3.10.01561343See
MEXMexico Sonora, Hermosillo0.015299See
SAUSaudi Arabia pop 42.80.0151499See
BRABrazil Belem Mixed3.00.0150100See
RUSRussia Northwest pop 33.00.0150100See
BRABrazil Parana Oriental3.00.015033See
USAUSA OPTN Caucasian0.01508525See
MKDMacedonia pop 30.0150172See
PAKPakistan Mixed Sindhi0.0150101See
SCOScotland Orkney2.90.015099See
AUSAustralia West Caucasian3.00.0150891See
MEXMexico Baja Californa, Mexicali0.0150100See
ECUEcuador Andes Mixed Ancestry0.0146824See
ENGEngland Sheffield2.80.01414755See
MEXMexico Tapachula, Chiapas Mestizo Population2.80.014072See
MEXMexico Chihuahua, Ciudad Juarez0.0139106See
POLPoland pop 32.80.01392907See
MEXMexico Coahuila Rural0.0138216See
CMRCameroon Ewondo0.013038See
ENGEngland Lancaster2.60.0130545See
MEXMexico Chihuahua Chihuahua City0.0126119See
MEXMexico Mexico City North0.0126751See
MEXMexico Puebla, Puebla city0.01251994See
ALBAlbanian Kosovo0.0125120See
GBRUnited Kingdom East0.0124163See
NORNorway ethnic Norwegians2.40.01224510See
MEXMexico Tabasco, Villahermosa0.012282See
GBRUnited Kingdom Orkney0.012088See
ENGEngland Leeds2.40.01205024See
INDIndia Kerala Hindu Nair0.012041See
RUSRussia Northwest2.40.01201011See
DEUGermany Essen2.30.0120174See
IRLIreland South pop 20.011617624See
MEXMexico Veracruz, Veracruz city0.0116171See
MEXMexico Queretaro Rural0.011643See
SWESweden pop 42.20.0114966See
MEXMexico Nuevo Leon, Monterrey city0.0111226See
BOLBolivia La Paz Aymaras0.011087See
RUSRussia Northwest pop 22.20.0110346See
WALWales pop 22.10.011039979See
ENGEngland Newcastle2.20.01102739See
ENGEngland Manchester2.10.01051640See
MEXMexico Aguascalientes state0.010595See
MEXMexico Nayarit, Tepic0.010397See
INDIndia North Gujarat2.10.0104338See
MEXMexico Puebla Mestizo0.010099See
PAKPakistan Burusho0.010092See
MNGMongolia Khalkha0.0100200See
PAKPakistan Mixed Pathan0.0100100See
RUSRussia Arkhangelsk Pomor0.010063See
MEXMexico Mexico City Metropolitan Area Rural0.0099150See
MEXMexico Sinaloa, Culiacán0.0097103See
LKASri Lanka Colombo Sinhalese0.0090101See
MEXMexico Sinaloa Mestizo0.009056See
MEXMexico Jalisco, Zapopan0.0089168See
MEXMexico Veracruz, Cordoba0.008956See
MEXMexico Veracruz, Coatzacoalcos0.008955See
SWESweden Uppsala1.70.0085300See
HRVCroatia pop 31.70.0083120See
MEXMexico Tlaxcala, Tlaxcala city0.0083181See
MEXMexico Veracruz, Xalapa0.0080187See
AREUnited Arab Emirates pop 21.60.0080373See
RUSRussia Nenet Mixed0.008055See
PAKPakistan Baloch0.008066See
MEXMexico Yucatan, Merida0.0077192See
CHNChina Shandong Province Linqu County1.50.0075139See
MEXMexico Tlaxcala Rural0.0072830See
RUSRussia Transbaikal Territory Buryats1.00.0070150See
PERPeru Arequipa Mestizo1.40.0070168See
MEXMexico Michoacan Tarasco1.50.0070130See
INDIndia North pop 30.0070587See
MEXMexico Guerrero state0.0069144See
MEXMexico Oaxaca, Oaxaca city0.0066151See
MEXMexico Chihuahua Rural0.0063236See
USAUSA OPTN Asian0.0060261See
VENVenezuela Colonia Tovar0.005886See
COLColombia Barranquilla0.0055188See
PAKPakistan Brahui0.0050104See
GBRUnited Kingdom pop 20.0050101See
MNGMongolia Khalkha pop 20.0050202See
GTMGuatemala, Guatemala City Mixed Ancestry0.80.0039127See
GBRUnited Kingdom Central0.0038135See
GBRUnited Kingdom South West0.0032163See
CHNChina Shaanxi Province Han0.003010000See
CHNChina Harbin Manchu0.0030172See
BRABrazil Parana Mixed race0.50.0030186See
TWNTaiwan Chinese immigrants from South China0.0030172See
CHNChina Shandong Province0.40.00207418See
RUSRussia South Ural Russian0.50.0020207See
MYSMalaysia pop 30.00101445See
CHNChina Jiangsu Province0.001020248See
TWNTaiwan Hakka pop 20.0010714See
CHNChina Shanghai0.000826266See
MYSMalaysia pop 20.000062See
MYSMalaysia Perak and Johor Banjar Bugis Jawa0.000094See
CHNChina Harbin Korean0.0000201See
JPNJapan Hyogo Osaka and Nagano0.0000195See
SAUSaudi Arabia0.00.000018See
CHNChina North Han0.0000105See
PAKPakistan Karachi Parsi0.000091See
INDIndia Kerala Syrian Christian0.000031See
INDIndia Kerala Kattunaikka0.000017See
INDIndia Kerala Kuruma0.000015See
INDIndia Kerala Malabar Muslim0.000034See
INDIndia Kerala Hindu Namboothiri0.000040See
INDIndia Kerala Paniya0.000010See
INDIndia Kerala Malapandaram0.000010See
INDIndia Kerala Adiya0.000021See
INDIndia Kerala Kurichiya0.000010See
INDIndia Kerala Hindu Pulaya0.000016See
TWNTaiwan Minnan pop 20.00007137See
TWNTaiwan Chinese immigrants from Middle China0.0000211See
TWNTaiwan Chinese immigrants from North China0.0000152See
TWNTaiwan Aborigine0.0000111See
TTOTrinidad South Asian0.000087See
MEXMexico Huasteca Region Teenek0.000055See
MEXMexico Mayan Pop 30.000066See
PAKPakistan Kalash0.000069See
MNGMongolia Oold0.0000104See
MNGMongolia Tsaatan0.0000144See
RUSRussia Murmansk Saomi Mixed0.000070See
ARGArgentina Chiriguano0.00.000054See
KORSouth Korea pop 10.0000324See
THAThailand pop 40.000016807See
KORSouth Korea pop 80.00007096See
NORNorway Sami0.0000200See
VNMVietnam Hanoi0.000050See
ECUEcuador Amazonia Mixed Ancestry0.000039See
MEXMexico Baja California, Tijuana0.000025See
MEXMexico Morelos Rural0.000030See
MEXMexico Quintana Roo Rural0.000050See
MEXMexico Mexico City East0.000079See
MEXMexico Veracruz, Poza Rica0.000045See
MEXMexico Tamaulipas, Ciudad Victoria0.000023See
MEXMexico Queretaro, Queretaro city0.000045See
MEXMexico Jalisco, Tonala0.000035See

Frequency data at lower resolution for this allele can be found in links below

Allele  Number of Populations 


* Allele Frequency: Total number of copies of the allele in the population sample (Alleles / 2n) in decimal format.
   Important: This field has been expanded to four decimals to better represent frequencies of large datasets (e.g. where sample size > 1000 individuals)
* Phenotype Frequency: Percentage of individuals who have the allele or gene (Individuals / n).
* Allele Frequencies shown in green were calculated from Phenotype Frequencies assuming Hardy-Weinberg proportions.

¹ IMGT/HLA Database - For more details of the allele.
² Distribution - Graphical distribution of the allele.
³ Haplotype Association - Find HLA haplotypes with this allele.
ª Notes - See notes for ambiguous combinations of alleles.


Allele frequency net database (AFND) 2020 update: gold-standard data classification, open access genotype data and new query tools
Gonzalez-Galarza FF, McCabe A, Santos EJ, Jones J, Takeshita LY, Ortega-Rivera ND, Del Cid-Pavon GM, Ramsbottom K, Ghattaoraya GS, Alfirevic A, Middleton D and Jones AR Nucleic Acid Research 2020, 48:D783-8.
Liverpool, U.K.

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