Allele Frequencies in World Populations

HLA Database » Allele Report

The list below shows all populations in AFND that contains the allele. If an allele has an entry with a lower resolution this will be shown at the end.



Allele reported 379 time(s) and present in 322 population(s).

Population Phenotype
Frequency (%)
Distribution² Haplotype³
SAUSaudi Arabia pop 20.1880383See
ARMArmenia living in Iran0.182085See
SAUSaudi Arabia pop 428.90.1627499See
TUNTunisia Ghannouch0.134082See
MARMorocco Casablanca0.0990100See
AREUnited Arab Emirates pop 218.00.0940373See
MEXMexico Campeche Rural0.074547See
ARMArmenia Lori0.0640102See
INDIndia Kerala Hindu Pulaya0.063016See
PRTMadeira pop 20.0630173See
MEXMexico Hidalgo, Pachuca0.061041See
RUSRussia North Ossetian10.20.0591127See
ARMArmenia Shirak0.059076See
GAZGaza Palestinians0.0580165See
ARMArmenia Syunik0.0560117See
PRTPortugal Bragança0.0560301See
IRNIran Royan Cord Blood Bank10.70.055015600See
ARMArmenia living in USA0.0540233See
RUSRussia, South Ural, Chelyabinsk region, Nagaybaks10.70.0540112See
ARMArmenia living in Lebanon0.0520368See
ARMArmenia Ghegharkunik0.0520242See
DZAAlgeria pop 210.00.0513106See
PRTAzores Terceira Island0.0510130See
TURTurkey pop 20.0500228See
MARMorocco pop 20.0500110See
IRQIraq Erbil10.00.0498372See
PRTPortugal Vila Real0.04801167See
ISRIsrael Ashkenazi Jews pop 20.0480132See
CZECzech Republic Kurd9.50.047374See
ARMArmenia living in Karabakh0.0470445See
ITAItaly Rome9.00.0450100See
ESPSpain Majorcans Jews0.0440103See
PRTMadeira pop 30.0440538See
IRQIraq Arabs8.70.0436149See
ARMArmenia Yerevan0.0430445See
ESPSpain Minorca0.043094See
RUSRussia Chuvash0.043082See
IRNIran pop 40.0421855See
VENVenezuela Caracas Mestizo0.040050See
TURTurkey pop 50.0390142See
PRTPortugal Porto0.03807937See
RUSRussia South Ural Bashkir7.50.0380146See
PRTPortugal Santarem0.03703865See
PRTPortugal Coimbra0.03705057See
PRTPortugal Aveiro0.03705933See
PRTPortugal North pop 20.03611801See
ESPSpain Sevilla6.80.0360278See
INDIndia North pop 30.0360587See
COLColombia San Basilio de Palenque0.036042See
GEOGeorgia Kurds0.036030See
VENVenezuela Valencia and Maracaibo Caracus Mixed0.036096See
ISRIsrael Moroccan Jews0.0360113See
MNGMongolia Khalkha pop 20.0350202See
MNGMongolia Tsaatan0.0350144See
PAKPakistan Mixed Pathan0.0350100See
PAKPakistan Mixed Sindhi0.0350101See
PRTPortugal Leiria0.03501847See
PRTPortugal Viana do Castelo0.0350706See
BRABrazil Belem Mixed7.00.0350100See
PRTPortugal Guarda0.0330797See
PRTPortugal Viseu0.03202915See
ISRIsrael Jews pop 26.30.032023000See
PRTPortugal Lisbon0.031017420See
PRTPortugal Portalegre0.03101254See
PRTPortugal Evora0.0310737See
PRTPortugal Center pop 20.0310562See
BRABrazil REDOME Goias0.030888574See
ITAItaly Lombardy6.10.0300674See
PRTPortugal Setubal0.03005268See
PRTPortugal Braga0.03001971See
BRABrazil REDOME Ceara0.0295101217See
RUSRussia Tatars0.0295355See
BRABrazil REDOME Rio Grande do Norte0.029446603See
ITAItaly North Pavia pop 30.0292685See
BRABrazil REDOME Acre0.0291859See
BRABrazil REDOME Minas Gerais0.0291211275See
BRABrazil REDOME Paraiba0.029043868See
RUSRussia South Ural Tatar5.90.0290135See
BRABrazil Rio Grande do Norte Mestizo0.029012973See
PRTPortugal Beja0.0290699See
PRTPortugal South pop 20.02901021See
HRVCroatia pop 20.0290100See
BRABrazil REDOME Piaui0.028546140See
BRABrazil REDOME Pernambuco0.028192332See
ESPSpain Murcia0.0280173See
MEXMexico Mestizo pop 40.0279269See
ESPSpain, Castilla y Leon, Northwest,6.00.02791743See
BRABrazil REDOME Federal District0.027829549See
BRABrazil REDOME Tocantins0.027520692See
BRABrazil Sao Paulo Bauru Mixed0.02703542See
BRABrazil Piaui Mixed0.027021943See
ITAItaly North Pavia pop 25.20.02702416See
MEXMexico Michoacan, Morelia0.0265150See
INDIndia Bikaner Raikas5.00.0260143See
ARGArgentina Cuyo Region5.20.0260420See
TWNTaiwan Chinese immigrants from North China0.0260152See
BRABrazil Rio Grande do Sul Mixed0.0260324See
MEXMexico Jalisco, Tlaquepaque0.025639See
MEXMexico Sonora Rural0.0254197See
MEXMexico Chihuahua Chihuahua City0.0252119See
BRABrazil REDOME Rio de Janeiro0.0252139322See
BRABrazil Pernambuco Mixed0.0250101See
VENVenezuela Zulia Maracaibo Mixed0.025020See
VENVenezuela Zulia San Jose de Heras Mixed0.025020See
BRABrazil Paraná Caucasian4.80.0250641See
MEXMexico Chiapas Rural0.0248121See
BRABrazil REDOME Roraima0.02454140See
BRABrazil South East Cord Blood0.024211409See
BRABrazil REDOME Maranhao0.024110180See
COLColombia Barranquilla0.0240188See
PRTPortugal Castelo Branco0.0240327See
PRTPortugal Faro0.02401242See
ARGArgentina La Plata5.00.0240100See
BRABrazil REDOME Sao Paulo0.0239800809See
MEXMexico Tamaulipas Rural0.0238125See
ARGArgentina Corrientes4.50.0230155See
ARGArgentina Buenos Aires4.70.0230466See
BRABrazil Minas Gerais State Mixed4.50.02301000See
CUBCuba Mixed pop 20.0230189See
ENGEngland London Ashkenazi Jews0.0230500See
BRABrazil REDOME Alagoas0.022925349See
BRABrazil REDOME Amazonas0.022924129See
MEXMexico Colima Rural0.022743See
BRABrazil Para State4.50.02265000See
BRABrazil REDOME Rondonia0.022654396See
BRABrazil REDOME Mato Grosso0.022534649See
BRABrazil REDOME Mato Grosso do Sul0.022395667See
MEXMexico Queretaro, Queretaro city0.022245See
BRABrazil Rio Grande do Sul Caucasoid0.02204428See
PAKPakistan Karachi Parsi0.022091See
BRABrazil Parana Caucasian4.30.02202775See
BRABrazil Parana Cafuzo4.40.0220319See
PRTPortugal North0.022046See
ITAItaly pop 64.40.0217184See
BRABrazil REDOME Para0.021572637See
COLColombia Wayu from Guajira Peninsula0.020848See
BRABrazil REDOME Parana0.0207341639See
INDIndia North Gujarat4.10.0207338See
BRABrazil REDOME Bahia0.020647399See
MEXMexico Nayarit, Tepic0.020697See
BRABrazil REDOME Espirito Santo0.020588485See
SDNSudan Khartoum0.020498See
BRABrazil REDOME Amapa0.020317864See
ESPSpain North4.00.0202156See
ROMRomania pop 20.02006936See
MNGMongolia Khalkha0.0200200See
BRABrazil Sao Paulo Mixed0.40.0200239See
BRABrazil Rio Grande do Sul Black0.0200248See
ITAItaly East Sicily4.00.020050See
MEXMexico Baja California, Tijuana0.020025See
BRABrazil REDOME Sergipe0.01997321See
BRABrazil REDOME Santa Catarina0.0195106673See
BRABrazil REDOME Rio Grande do Sul0.0192241329See
BRABrazil Para Cord Blood Unit3.80.0190841See
KURIraq Kurdistan Region3.80.0190209See
PAKPakistan Brahui0.0190104See
ARGArgentina Buenos Aires pop 23.60.01901216See
GBRUnited Kingdom Central0.0188135See
MEXMexico Chihuahua Rural0.0188236See
MEXMexico Jalisco Rural0.0188585See
ITAItaly South Campania Region3.70.01861089See
MEXMexico Chihuahua, Ciudad Juarez0.0185106See
ROMRomania pop 33.70.01841469See
MEXMexico Morelos, Cuernavaca0.018382See
FRAFrance Marseille3.60.01791000See
ENGEngland Lancaster3.50.0176545See
MEXMexico San Luis Potosi Rural0.017287See
FRAFrance Lyon3.40.01714813See
USAUSA OPTN Hispanic0.01701580See
BIHBosnia and Herzegovina pop 23.30.0167120See
MEXMexico Jalisco, Tlajomulco0.016730See
MEXMexico Veracruz, Xalapa0.0160187See
IRNIran pop 10.016064See
SVNSlovenia pop 33.10.0160130See
BRABrazil Parana Mixed race3.20.0160186See
GRCGreece pop 70.015511250See
MEXMexico Nuevo Leon, Monterrey city0.0155226See
MEXMexico Guanajuato Rural0.0153162See
BRABrazil Parana Oriental3.00.015033See
ESPSpain Majorca0.0150407See
GRCGreece North0.0150500See
MEXMexico Yucatan Rural0.0149132See
RUSRussia Moscow Pop 23.00.01472000See
CHLChile Santiago0.0147920See
BRABrazil Curitiba-Parana Mixed0.0144264See
MEXMexico Zacatecas, Fresnillo0.0143103See
RUSRussia Moscow0.01402650See
BRABrazil South Ribeirao Preto0.0140184See
GBRUnited Kingdom North0.0138330See
SVKSlovakia pop 20.01364234See
MEXMexico Mexico City Metropolitan Area Rural0.0132150See
ESPSpain North Cabuerniga0.013095See
BRABrazil Parana Afro Brazilian2.60.013077See
FRAFrance Grenoble, Nantes and Rennes0.01306094See
GBRUnited Kingdom South West0.0129163See
ALBAlbania pop 22.30.0127432See
FRAFrance Bordeaux2.50.0125990See
ALBAlbanian Kosovo0.0125120See
MEXMexico Nuevo Leon Rural0.0125439See
MEXMexico Coahuila, Torreon0.0125396See
MEXMexico Hidalgo Rural0.012381See
POLPoland pop 32.40.01222907See
CMRCameroon Podokwo0.012043See
RUSRussia South Ural Russian2.40.0120207See
MEXMexico Mexico City Mestizo0.0120121See
SRBSerbia Vojvodina2.50.0120400See
ENGEngland Newcastle2.40.01202739See
ENGEngland Manchester2.40.01201640See
ZAFSouth Africa Tswana2.40.012041See
AUSAustralia West Caucasian2.50.0120891See
FRAFrance Southeast2.30.0120130See
ENGEngland North West Mixed pop 22.40.0119379See
GTMGuatemala, Guatemala City Mixed Ancestry2.40.0118127See
MKDMacedonia MBMDR - Albanian2.30.0117128See
MEXMexico Coahuila Rural0.0115216See
SRBSerbia pop 32.30.01131992See
USAUSA African American Bethesda2.10.0110187See
GTMGuatemala Mayan0.0110132See
CHNChina Shandong Province Linqu County2.20.0110139See
USAUSA OPTN Caucasian0.01108525See
USAUSA OPTN African American0.01101510See
ECUEcuador Andes Mixed Ancestry0.0109824See
FRAFrance Rennes pop 42.20.01091000See
MMRMyanmar Bamar2.20.010946See
MEXMexico Quintana Roo, Cancun0.010448See
FRAFrance Grenoble2.10.01031000See
FRAFrance Rennes pop 30.0100200See
GBRUnited Kingdom pop 20.0100101See
GRCGreece pop32.00.0100246See
TTOTrinidad South Asian0.010087See
MNGMongolia Oold0.0100104See
RUSRussia Transbaikal Territory Buryats2.00.0100150See
SWESweden pop 42.00.0098966See
MEXMexico Puebla Rural0.0096833See
MEXMexico Mexico City South0.009652See
ENGEngland Liverpool1.90.00951343See
ECUEcuador Mixed Ancestry0.00941173See
GBRUnited Kingdom East0.0093163See
MEXMexico Zacatecas Rural0.0093266See
CHNChina Shaanxi Province Han0.009010000See
WALWales pop 21.70.009039979See
ENGEngland Leeds1.80.00905024See
RUSRussia Sakhalin Island Nivkhi0.009053See
ENGEngland Sheffield1.80.00904755See
DEUGermany Essen1.70.0090174See
MEXMexico Veracruz, Cordoba0.008956See
MEXMexico Puebla, Puebla city0.00851994See
RUSRussia Northwest1.70.00851011See
HRVCroatia pop 31.70.0083120See
MEXMexico Oaxaca Rural0.0082485See
CHNChina Wuhan1.70.0080121See
PAKPakistan Baloch0.008066See
CHNChina Shandong Province1.60.00807418See
MEXMexico Durango Rural0.0076326See
MEXMexico Veracruz Rural0.0074539See
BIHBosnia and Herzegovina0.0074134See
IRLIreland South pop 20.007317624See
MEXMexico Michoacan Rural0.0072348See
MEXMexico Sonora, Ciudad Obregón0.0070143See
RUSRussia Samara Region0.00702500See
CUBCuba Mixed0.007078See
PERPeru Arequipa Mestizo1.40.0070168See
TTOTrinidad African0.007067See
MKDMacedonia pop 40.0070216See
MEXMexico Baja California, La Paz0.006775See
MKDMacedonia MBMDR - Macedonian Muslims1.30.006676See
MEXMexico Durango, Durango city0.0065153See
MEXMexico Guanajuato, Leon0.006478See
MKDMacedonia MBMDR - Macedonian1.20.00621283See
MEXMexico Tabasco, Villahermosa0.006182See
RUSRussia Northwest pop 21.10.0060346See
MKDMacedonia pop 30.0060172See
MEXMexico Nahuas0.006072See
CHNChina Harbin Manchu0.0060172See
BOLBolivia La Paz Aymaras0.006087See
MEXMexico Jalisco, Zapopan0.0060168See
MEXMexico Jalisco, Guadalajara city0.00591189See
MEXMexico Veracruz, Veracruz city0.0058171See
VENVenezuela Colonia Tovar0.005886See
MEXMexico Sinaloa Rural0.0055183See
MEXMexico Tlaxcala Rural0.0054830See
INDIndia Bikaner Non-Raikas1.00.0050127See
PAKPakistan Burusho0.005092See
SENSenegal Dakar0.90.0050112See
GRCGreece Crete0.0050135See
CHNChina Guangdong Province1.00.0050403See
CHNChina Jiangsu Province0.005020248See
FRAFrance Reims0.0050102See
RUSRussia Northwest pop 31.00.0050100See
MEXMexico Puebla Mestizo0.005099See
MEXMexico Mexico City North0.0046751See
ECUEcuador Coast Mixed Ancestry0.0042238See
CHNChina Shanghai0.004026266See
USAUSA Caucasian Bethesda0.80.0040307See
NORNorway ethnic Norwegians0.70.00374510See
MEXMexico Guerrero state0.0035144See
MEXMexico Tabasco Rural0.0035142See
MEXMexico Mexico City Center0.0032152See
MEXMexico Tlaxcala, Tlaxcala city0.0028181See
MEXMexico Yucatan, Merida0.0026192See
BRABrazil Parana Japanese1.00.0026192See
USAUSA OPTN Asian0.0020261See
KORSouth Korea pop 10.0020324See
TWNTaiwan Minnan pop 20.00107137See
MYSMalaysia pop 30.00101445See
THAThailand pop 40.001016807See
KORSouth Korea pop 80.00107096See
TZATanzania Dodoma Kongwa0.0000212See
MEXMexico Sinaloa Mestizo0.000056See
CMRCameroon Ewondo0.000038See
CMRCameroon Bamileke 20.000035See
CMRCameroon Uldeme0.000035See
MEXMexico Campeche, Campeche city0.000034See
MEXMexico Chiapas, Tuxtla Gutierrez0.000052See
MEXMexico Mexico City West0.000033See
ECUEcuador Amazonia Mixed Ancestry0.000039See
GBRUnited Kingdom Orkney0.000088See
MYSMalaysia pop 20.000062See
CHNChina North Han0.0000105See
INDIndia Kerala Hindu Nair0.000041See
INDIndia Kerala Syrian Christian0.000031See
INDIndia Kerala Hindu Ezhava0.000024See
INDIndia Kerala Malabar Muslim0.000034See
INDIndia Kerala Hindu Namboothiri0.000040See
SAUSaudi Arabia0.00.000018See
TWNTaiwan Chinese immigrants from South China0.0000172See
TWNTaiwan Chinese immigrants from Middle China0.0000211See
SWESweden Uppsala0.00.0000300See
TWNTaiwan Aborigine0.0000111See
TWNTaiwan Hakka pop 20.0000714See
CHNChina Harbin Korean0.0000201See
JPNJapan Hyogo Osaka and Nagano0.0000195See
MEXMexico Huasteca Region Teenek0.000055See
MEXMexico Mayan Pop 30.000066See
SCOScotland Orkney0.00.000099See
ZAFSouth Africa Natal Zulu0.00.0000100See
RUSRussia Nenet Mixed0.000055See
RUSRussia Arkhangelsk Pomor0.000063See
RUSRussia Murmansk Saomi Mixed0.000070See
ARGArgentina Chiriguano0.00.000054See
ARGArgentina Salta Wichi pop 20.00.000019See
ESPSpain Ibiza0.000088See
PAKPakistan Kalash0.000069See
MEXMexico Oaxaca, Oaxaca city0.0000151See
MEXMexico Mexico City East0.000079See
MEXMexico Veracruz, Poza Rica0.000045See
MEXMexico Veracruz, Orizaba0.000060See
MEXMexico Veracruz, Coatzacoalcos0.000055See
MEXMexico San Luis Potosi, San Luis Potosi city0.000030See
MEXMexico Tamaulipas, Ciudad Victoria0.000023See
MEXMexico Zacatecas, Zacatecas city0.000084See
MEXMexico Coahuila, Saltillo0.000072See
MEXMexico Jalisco, Tonala0.000035See
MEXMexico Guanajuato, Guanajuato city0.000022See
MEXMexico Colima, Colima city0.000061See
MEXMexico Aguascalientes state0.000095See
MEXMexico Morelos Rural0.000030See
MEXMexico Quintana Roo Rural0.000050See
MEXMexico Queretaro Rural0.000043See
MEXMexico Baja California Rural0.000050See
MEXMexico Baja Californa, Mexicali0.0000100See
MEXMexico Sinaloa, Culiacán0.0000103See
MEXMexico Sonora, Hermosillo0.000099See
MEXMexico Nayarit Rural0.000064See

Frequency data at lower resolution for this allele can be found in links below

Allele  Number of Populations 


* Allele Frequency: Total number of copies of the allele in the population sample (Alleles / 2n) in decimal format.
   Important: This field has been expanded to four decimals to better represent frequencies of large datasets (e.g. where sample size > 1000 individuals)
* Phenotype Frequency: Percentage of individuals who have the allele or gene (Individuals / n).
* Allele Frequencies shown in green were calculated from Phenotype Frequencies assuming Hardy-Weinberg proportions.

¹ IMGT/HLA Database - For more details of the allele.
² Distribution - Graphical distribution of the allele.
³ Haplotype Association - Find HLA haplotypes with this allele.
ª Notes - See notes for ambiguous combinations of alleles.


Allele frequency net database (AFND) 2020 update: gold-standard data classification, open access genotype data and new query tools
Gonzalez-Galarza FF, McCabe A, Santos EJ, Jones J, Takeshita LY, Ortega-Rivera ND, Del Cid-Pavon GM, Ramsbottom K, Ghattaoraya GS, Alfirevic A, Middleton D and Jones AR Nucleic Acid Research 2020, 48:D783-8.
Liverpool, U.K.

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