Allele Frequencies in World Populations

HLA Database » Allele Report

The list below shows all populations in AFND that contains the allele. If an allele has an entry with a lower resolution this will be shown at the end.



Allele reported 265 time(s) and present in 252 population(s).

Population Phenotype
Frequency (%)
Distribution² Haplotype³
ITAItaly North pop 346.60.232097See
JPNJapan Hokkaido Ainu0.190050See
CHNChina Uyghur HIV negative0.184019See
ARMArmenia combined Regions0.1750100See
GRCGreece pop 830.10.174783See
GRCGreece pop 60.1722242See
CHNChina Tibet Region Tibetan0.1680158See
GEOGeorgia Svaneti Region Svan0.156080See
SAUSaudi Arabia Guraiat and Hail26.30.1490213See
CHESwitzerland Lugano0.13831169See
AREUnited Arab Emirates Abu Dhabi0.134652See
USAUSA South Dakota Lakota Sioux0.1300302See
PRTPortugal North0.130046See
DEUGermany DKMS - Greece minority0.12801894See
SRBSerbia pop 223.50.1230102See
DEUGermany DKMS - Turkey minority0.12174856See
MEXMexico Sonora Seri0.121034See
PRTPortugal Center0.120050See
MEXMexico Chihuahua Chihuahua City Pop 223.90.119388See
DEUGermany DKMS - Bosnia and Herzegovina minority0.11771028See
IRNIran Yazd0.116156See
PRTPortugal South0.112049See
USAUSA North American Native0.1120187See
HRVCroatia pop 40.11134000See
TUNTunisia Gabes0.105295See
DEUGermany DKMS - Croatia minority0.10382057See
USAUSA Alaska Yupik0.1030252See
CHNChina Guizhou Province Miao pop 20.102085See
CHESwitzerland Graubunden0.1009759See
MYSMalaysia Peninsular Indian18.50.0996271See
ARGArgentina Rosario Toba18.60.099086See
PRTAzores Central Islands0.098059See
CHESwitzerland Sion0.0967832See
MYSMalaysia Kedah Kensiu19.10.095021See
KORSouth Korea pop 100.09464128See
IRNIran Kurd pop 20.092060See
AREUnited Arab Emirates Pop 10.0920570See
USAUSA NMDP Korean0.091877584See
IRNIran Saqqez-Baneh Kurds0.091760See
CHESwitzerland Aargau-Solothurn0.09001838See
PRTAzores Oriental Islands0.090043See
JPNJapan pop 160.089318604See
USAUSA NMDP Japanese0.089024582See
PRTAzores Terceira Island0.0890130See
ESPSpain Andalusia0.088099See
IRNIran Tabriz Azeris0.087697See
ISRIsrael Druze0.08645914See
DEUGermany DKMS - Portugal minority0.08591176See
INDIndia Tamil Nadu0.08542492See
INDIndia South UCBB16.90.084711446See
CHLChile Mapuche0.084666See
CHNChina Yunnan Province Han0.0840101See
KORSouth Korea pop 30.0840485See
SGPSingapore Chinese15.40.0840149See
BRABrazil Belo Horizonte Caucasian14.70.084095See
PRTPortugal Azores Terceira Island16.70.0833130See
JPNJapan pop 30.08301018See
ITAItaly pop 50.0800975See
INDIndia North UCBB15.70.07865849See
DEUGermany DKMS - Spain minority0.07831107See
USAUSA NMDP Middle Eastern or North Coast of Africa0.078170890See
CHESwitzerland Bern0.07793545See
JPNJapan Central0.0770371See
ESPSpain Andalusia Romani0.076099See
ISRIsrael Arab pop 20.075912301See
USAUSA NMDP South Asian Indian0.0747185391See
ESPSpain (Catalunya, Navarra, Extremadura, Aaragón, Cantabria,14.50.07464335See
DEUGermany DKMS - Austria minority0.07451698See
FRAFrance French Bone Marrow Donor Registry0.074342623See
DEUGermany DKMS - Romania minority0.07421234See
DEUGermany DKMS - Italy minority0.07421159See
ISRIsrael Iraq Jews0.074213270See
ISRIsrael Georgia Jews0.07154471See
MYSMalaysia Kelantan14.30.071028See
CHESwitzerland Zurich0.07094875See
JPNJapan pop 50.0700117See
CHESwitzerland St Gallen0.06882113See
DEUGermany DKMS - France minority0.06791406See
USAUSA NMDP North American Amerindian0.067835791See
CHESwitzerland Luzern0.06761553See
INDIndia West UCBB13.50.06765829See
USAUSA Asian0.0670358See
USAUSA NMDP Southeast Asian0.067027978See
CHESwitzerland Lausanne0.0661993See
JORJordan Amman0.0660146See
SGPSingapore SGVP Chinese CHS0.065096See
CUBCuba Caucasian12.90.064070See
USAUSA NMDP Caribean Hispanic0.0638115374See
DEUGermany pop 80.063239689See
SDNSudan Mixed11.50.0630200See
STPSao Tome Island Angolar0.063032See
USAUSA Asian pop 20.06281772See
USAUSA Hispanic0.0620234See
USAUSA NMDP Caribean Indian0.062014339See
INDIndia Central UCBB12.40.06174204See
STPSao Tome Island Forro0.061066See
USAUSA NMDP Hispanic South or Central American0.0605146714See
MYSMalaysia Sarawak Bau Bidayuh0.060025See
INDIndia Delhi pop 212.10.060090See
MEXMexico Mexico City Mestizo pop 20.0598234See
MEXMexico Tixcacaltuyub Maya0.059767See
FRAFrance Southeast11.50.0590130See
USAUSA NMDP Mexican or Chicano0.0578261235See
USAUSA Hispanic pop 20.05781999See
USAUSA European American pop 20.05701245See
ZMBZambia Lusaka0.057044See
USAUSA Caucasian pop 20.0570265See
USAUSA NMDP Alaska Native or Aleut0.05701376See
LKASri Lanka Colombo10.80.0570714See
DEUGermany DKMS - German donors0.05683456066See
COLColombia Bogotá Cord Blood11.00.05641463See
USAUSA NMDP American Indian South or Central America0.05605926See
NLDNetherlands Leiden0.05601305See
CHNChina Southwest Dai0.0560124See
MEXMexico Mexico City Mestizo population0.0559143See
DEUGermany pop 60.05538862See
CHNChina Guangzhou0.0550102See
IRNIran Gorgan0.055064See
MEXMexico Mexico City Tlalpan10.90.0545330See
CHNChina Beijing Shijiazhuang Tianjian Han0.0540618See
CHNChina Beijing0.053067See
CHNChina Marrow Donor Registry0.0520600See
CHNChina Hubei Han10.30.05173732See
DEUGermany DKMS - Netherlands minority0.05171374See
CZECzech Republic NMDR0.05125099See
ISRIsrael Ethiopia Jews0.05095928See
USAUSA San Diego9.90.0500496See
BRABrazil Puyanawa9.30.0500150See
UGAUganda Kampala0.0500161See
MEXMexico Mestizo9.80.049041See
CHNChina Canton Han0.0490264See
CUBCuba Mixed Race9.50.048042See
INDIndia East UCBB9.60.04792403See
CHESwitzerland Geneva pop 20.04771267See
MEXMexico Veracruz Xalapa9.50.047684See
USAUSA NMDP European Caucasian0.04731242890See
POLPoland DKMS0.047120653See
ENGEngland North West9.40.0470298See
NLDNetherlands UMCU9.40.046964See
CHNChina Jiangsu Province Han0.0467334See
CHESwitzerland Basel0.04611888See
CHNChina Jiangsu Han0.04603238See
USAUSA NMDP Chinese0.045799672See
DEUGermany DKMS - China minority0.04531282See
USAUSA San Antonio Caucasian0.0452222See
AUSAustralia New South Wales Caucasian0.0450134See
RUSRussia Karelia0.04491075See
SGPSingapore SGVP. Indian INS0.044086See
TWNTaiwan Han Chinese0.0440504See
CHNChina Guizhou Province Shui0.0440153See
ISRIsrael Tunisia Jews0.04349070See
HKGHong Kong Chinese cord blood registry0.04303892See
USAUSA South Texas Hispanic0.0430194See
MARMorocco Nador Metalsa pop 20.043073See
HKGHong Kong Chinese8.60.0430569See
TWNTaiwan Tzu Chi Morrow Donor Registry0.042446682See
NICNicaragua Managua8.40.0422339See
HKGHong Kong Chinese BMDR0.04217595See
KENKenya Nandi0.0420240See
ISRIsrael Iran Jews0.04158153See
DEUGermany DKMS - United Kingdom minority0.04151043See
USAUSA Philadelphia Caucasian7.40.0410141See
TWNTaiwan Tzu Chi Cord Blood Bank0.0400710See
USAUSA Caucasian pop 40.03911070See
TWNTaiwan pop 30.0390212See
MEXMexico Oaxaca Mixtec0.0390103See
CHNChina Yunnan Bulang0.0390116See
USAUSA San Francisco Caucasian0.0390220See
ISRIsrael Kavkazi Jews0.03772840See
USAUSA NMDP Filipino0.037650614See
TZATanzania Maasai7.20.0374336See
MYSMalaysia Peninsular Malay7.50.0373951See
ARGArgentina Gran Chaco Western Toba Pilaga7.10.036019See
CHLChile Santiago Mixed7.00.035670See
VNMVietnam Hanoi Kinh pop 20.0350170See
SWESweden Southern Sami0.0350130See
ARGArgentina Gran Chaco Eastern Toba6.00.0350135See
IDNIndonesia Java Western6.40.0330236See
TWNTaiwan pop 20.0320364See
CMRCameroon Bamileke0.032077See
ISRIsrael Argentina Jews0.03114307See
CHNChina Han HIV negative0.031072See
CHNChina Henan HIV negative0.031016See
INDIndia Northeast UCBB6.10.0304296See
KENKenya, Nyanza Province, Luo tribe6.00.0300100See
ISRIsrael USSR Jews0.029145681See
RUSRussia Bering Island Aleuts0.0288104See
ISRIsrael YemenJews0.028115542See
USAUSA Caucasian Bethesda5.40.0270307See
NIRIreland Northern5.20.02701000See
USAUSA African American Bethesda5.30.0260187See
MEXMexico Mixtec0.026097See
MEXMexico Oaxaca Jamiltepec Mixtec0.026096See
MYSMalaysia Peninsular Chinese5.20.0258194See
MLIMali Bandiagara0.0250138See
USAUSA NMDP African0.024128557See
USAUSA NMDP Hawaiian or other Pacific Islander0.023611499See
ISRIsrael Bukhara Jews0.02302317See
KENKenya Luo0.0230265See
CHNChina Shanxi HIV negative0.023022See
ISRIsrael USA Jews0.02296058See
USAUSA NMDP Vietnamese0.022843540See
USAUSA NMDP Caribean Black0.022633328See
MEXMexico Oaxaca Zapotec0.022090See
USAUSA African American pop 40.02182411See
USAUSA NMDP African American pop 20.0217416581See
USAUSA African American pop 80.0210605See
ISRIsrael Poland Jews0.020113871See
CHNChina Guizhou Province Bouyei0.0200109See
GHAGhana Ga-Adangbe3.80.0191131See
ZAFSouth Africa Worcester4.00.0190159See
MYSMalaysia Mandailing3.70.019027See
CHNChina Guangxi Region Maonan0.0190108See
NCLNew Caledonia0.019065See
IRLIreland South3.60.0180250See
MYSMalaysia Champa3.50.017029See
ISRIsrael Ashkenazi Jews pop 30.01524625See
PERPeru Titikaka Lake Uros0.0140105See
PERPeru Titikaka Lake Uro0.0140105See
CMRCameroon Beti0.0140174See
MYSMalaysia Pahang Semai2.60.013038See
TWNTaiwan Tzu Chi Morrow Donor Registry Aborigine0.0129233See
ITAItaly North Pavia0.012081See
USAUSA African American0.0120252See
USAUSA African American pop 30.0110564See
MEXMexico Chichen Itza Maya (prehispanic)0.010647See
CHNChina Yunnan Hani0.0100150See
SWESweden Northern Sami0.0100154See
TWNTaiwan Siraya2.00.010051See
COLColombia North Wiwa El Encanto0.009652See
MEXMexico Chiapas Lacandon Mayans0.0092218See
MEXMexico Oaxaca Mixe0.009055See
CZECzech Republic0.0090106See
BRABrazil Terena1.70.009060See
UGAUganda Kampala pop 20.0090175See
ISRIsrael Morocco Jews0.007436718See
AUSAustralia Groote Eylandt Aborigine0.007075See
SGPSingapore SGVP Malay MAS0.006089See
ISRIsrael Libya Jews0.00403739See
ZWEZimbabwe Harare Shona0.0040230See
USAUSA Arizona Gila River Amerindian0.0020492See
CMRCameroon Sawa0.000013See
CMRCameroon Baka Pygmy0.000010See
AUSAustralia Yuendumu Aborigine0.0000191See
ARGArgentina Gran Chaco Mataco Wichi0.00.000049See
CHNChina North Han0.0000105See
PNGPapua New Guinea Eastern Highlands Goroka Asaro0.000057See
PNGPapua New Guinea Madang0.000065See
PNGPapua New Guinea East New Britain Rabaul0.000060See
PNGPapua New Guinea West Schrader Ranges Haruai0.000055See
PNGPapua New Guinea Karimui Plateau Pawaia0.000080See
PNGPapua New Guinea Wosera Abelam0.0000131See
PNGPapua New Guinea Wanigela Keapara0.000066See
ZAFSouth Africa Natal Zulu0.00.0000100See
BRABrazil Vale do Ribeira Quilombos0.00.0000144See

Frequency data at lower resolution for this allele can be found in links below

Allele  Number of Populations 


* Allele Frequency: Total number of copies of the allele in the population sample (Alleles / 2n) in decimal format.
   Important: This field has been expanded to four decimals to better represent frequencies of large datasets (e.g. where sample size > 1000 individuals)
* Phenotype Frequency: Percentage of individuals who have the allele or gene (Individuals / n).
* Allele Frequencies shown in green were calculated from Phenotype Frequencies assuming Hardy-Weinberg proportions.

¹ IMGT/HLA Database - For more details of the allele.
² Distribution - Graphical distribution of the allele.
³ Haplotype Association - Find HLA haplotypes with this allele.
ª Notes - See notes for ambiguous combinations of alleles.


Allele frequency net database (AFND) 2020 update: gold-standard data classification, open access genotype data and new query tools
Gonzalez-Galarza FF, McCabe A, Santos EJ, Jones J, Takeshita LY, Ortega-Rivera ND, Del Cid-Pavon GM, Ramsbottom K, Ghattaoraya GS, Alfirevic A, Middleton D and Jones AR Nucleic Acid Research 2020, 48:D783-8.
Liverpool, U.K.

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