Allele Frequencies in World Populations

HLA Database » Allele Report

The list below shows all populations in AFND that contains the allele. If an allele has an entry with a lower resolution this will be shown at the end.



Allele reported 361 time(s) and present in 314 population(s).

Population Phenotype
Frequency (%)
Distribution² Haplotype³
CMRCameroon Podokwo0.314043See
CMRCameroon Uldeme0.214035See
TTOTrinidad African0.140067See
USAUSA African American Bethesda25.50.1380187See
IRNIran pop 10.133064See
CMRCameroon Bamileke 20.129035See
VENVenezuela Zulia San Jose de Heras Mixed0.125020See
CMRCameroon Ewondo0.118038See
USAUSA OPTN African American0.11501510See
SENSenegal Dakar21.40.1110112See
TZATanzania Dodoma Kongwa0.0910212See
PAKPakistan Brahui0.0770104See
CUBCuba Mixed pop 20.0750189See
MEXMexico Colima Rural0.068243See
COLColombia San Basilio de Palenque0.060042See
HRVCroatia pop 20.0500100See
VENVenezuela Zulia Maracaibo Mixed0.050020See
MNGMongolia Tarialan Khoton0.049085See
BRABrazil Rio Grande do Sul Black0.0480248See
BRABrazil REDOME Bahia0.046247399See
DZAAlgeria pop 29.00.0460106See
PAKPakistan Baloch0.046066See
SAUSaudi Arabia pop 20.0460383See
MEXMexico Veracruz, Coatzacoalcos0.044655See
SDNSudan South Nuba8.70.044446See
MEXMexico Campeche, Campeche city0.044134See
SDNSudan Central Shaigiya Mixed8.30.042436See
VENVenezuela Valencia and Maracaibo Caracus Mixed0.042096See
BRABrazil Sao Paulo Mixed0.80.0400239See
MEXMexico Nayarit Rural0.039164See
BRABrazil Parana Afro Brazilian7.80.039077See
BRABrazil Minas Gerais State Mixed7.50.03901000See
MEXMexico Guanajuato, Leon0.038578See
MARMorocco Casablanca0.0370100See
IRQIraq Arabs7.40.0369149See
SAUSaudi Arabia pop 46.20.0351499See
BRABrazil Pernambuco Mixed0.0350101See
BRABrazil REDOME Tocantins0.033920692See
BRABrazil REDOME Sergipe0.03377321See
MEXMexico Baja California, La Paz0.033375See
BRABrazil Piaui Mixed0.033021943See
BRABrazil Parana Cafuzo6.60.0330319See
ESPSpain Arratia Valley Basque0.033083See
BRABrazil REDOME Piaui0.032946140See
MEXMexico Chihuahua, Ciudad Juarez0.0324106See
COLColombia Barranquilla0.0320188See
GRCGreece Crete0.0320135See
PRTMadeira pop 20.0320173See
BRABrazil REDOME Maranhao0.031210180See
ISRIsrael Moroccan Jews0.0310113See
BRABrazil REDOME Espirito Santo0.030588485See
BRABrazil REDOME Rio de Janeiro0.0305139322See
BRABrazil REDOME Pernambuco0.030492332See
MEXMexico Baja Californa, Mexicali0.0300100See
MEXMexico Baja California Rural0.030050See
BRABrazil REDOME Paraiba0.029643868See
BRABrazil Para Cord Blood Unit5.70.0291841See
BRABrazil REDOME Rio Grande do Norte0.029146603See
BRABrazil Rio Grande do Sul Mixed0.0290324See
BRABrazil REDOME Minas Gerais0.0284211275See
BRABrazil South East Cord Blood0.028411409See
BRABrazil REDOME Alagoas0.028225349See
BRABrazil Rio Grande do Norte Mestizo0.028012973See
BRABrazil Paraná Caucasian5.50.0273641See
MEXMexico Sinaloa Rural0.0273183See
BRABrazil REDOME Rondonia0.027254396See
MEXMexico Sinaloa Mestizo0.027056See
BRABrazil South Ribeirao Preto0.0270184See
BRABrazil Parana Mixed race5.40.0270186See
BRABrazil REDOME Mato Grosso0.026234649See
BRABrazil REDOME Roraima0.02624140See
MEXMexico Jalisco, Tlaquepaque0.025639See
BRABrazil REDOME Amapa0.025017864See
ITAItaly North Pavia0.025081See
BRABrazil REDOME Goias0.024788574See
MEXMexico Hidalgo Rural0.024781See
MEXMexico Colima, Colima city0.024661See
BRABrazil REDOME Para0.024172637See
BRABrazil REDOME Federal District0.024129549See
GAZGaza Palestinians0.0240165See
BRABrazil REDOME Sao Paulo0.0239800809See
BRABrazil REDOME Ceara0.0236101217See
BRABrazil REDOME Amazonas0.022424129See
MEXMexico Yucatan Rural0.0224132See
BRABrazil REDOME Acre0.0221859See
AREUnited Arab Emirates pop 24.30.0220373See
BRABrazil Para State4.20.02205000See
MEXMexico Tamaulipas, Ciudad Victoria0.021723See
BRABrazil REDOME Mato Grosso do Sul0.021695667See
ECUEcuador Coast Mixed Ancestry0.0210238See
BRABrazil Sao Paulo Bauru Mixed0.02103542See
MEXMexico Chihuahua Chihuahua City0.0210119See
COLColombia Wayu from Guajira Peninsula0.020848See
MEXMexico Jalisco, Zapopan0.0208168See
ESPSpain North4.00.0202156See
ROMRomania pop 20.02006936See
USAUSA OPTN Hispanic0.02001580See
ITAItaly Rome4.00.0200100See
BRABrazil Belem Mixed4.00.0200100See
MEXMexico Baja California, Tijuana0.020025See
ESPSpain Sevilla3.60.0198278See
MEXMexico Mexico City Metropolitan Area Rural0.0197150See
MEXMexico Oaxaca Rural0.0195485See
GBRUnited Kingdom Central0.0188135See
GBRUnited Kingdom East0.0186163See
GEOGeorgia Kurds0.018030See
MARMorocco pop 20.0180110See
PRTPortugal Guarda0.0180797See
MEXMexico Zacatecas, Zacatecas city0.017984See
MEXMexico Veracruz, Veracruz city0.0174171See
PRTPortugal Portalegre0.01701254See
PRTPortugal Beja0.0170699See
BRABrazil REDOME Parana0.0169341639See
MEXMexico Jalisco, Tlajomulco0.016730See
MEXMexico Chihuahua Rural0.0167236See
MEXMexico Tlaxcala, Tlaxcala city0.0166181See
GRCGreece pop33.30.0166246See
ISRIsrael Ashkenazi Jews pop 20.0160132See
FRAFrance Southeast3.10.0160130See
SVNSlovenia pop 33.10.0160130See
PRTMadeira pop 30.0160538See
MEXMexico Mexico City Mestizo pop 30.0160256See
MEXMexico Tamaulipas Rural0.0159125See
MKDMacedonia MBMDR - Albanian3.10.0156128See
MEXMexico Nayarit, Tepic0.015597See
GBRUnited Kingdom North0.0154330See
SDNSudan Khartoum0.015398See
MEXMexico Puebla Mestizo0.015099See
ITAItaly North Pavia pop 30.0150685See
PRTPortugal Castelo Branco0.0150327See
FRAFrance Reims0.0150102See
MEXMexico Mayan Pop 30.015066See
PRTPortugal North pop 20.01471801See
PRTPortugal Lisbon0.014017420See
PRTPortugal Faro0.01401242See
MEXMexico Sonora, Ciudad Obregón0.0140143See
MEXMexico Veracruz, Xalapa0.0134187See
BRABrazil REDOME Santa Catarina0.0131106673See
PRTPortugal Coimbra0.01305057See
PRTPortugal Leiria0.01301847See
PRTPortugal Santarem0.01303865See
PRTPortugal Setubal0.01305268See
PRTPortugal Vila Real0.01301167See
ESPSpain North Cabuerniga0.013095See
ISRIsrael Jews pop 22.60.013023000See
MEXMexico Durango, Durango city0.0129153See
BRABrazil REDOME Rio Grande do Sul0.0127241329See
MEXMexico Jalisco, Guadalajara city0.01261189See
MEXMexico Puebla, Puebla city0.01251994See
MEXMexico Chiapas Rural0.0124121See
MEXMexico Durango Rural0.0122326See
MEXMexico Hidalgo, Pachuca0.012241See
ITAItaly Lombardy2.40.0120674See
BRABrazil Rio Grande do Sul Caucasoid0.01204428See
MEXMexico Mexico City Mestizo0.0120121See
KURIraq Kurdistan Region2.40.0120209See
MNGMongolia Ulaanbaatar Khalkha0.012041See
PRTPortugal Viseu0.01202915See
PRTPortugal Evora0.0120737See
ZAFSouth Africa Tswana2.40.012041See
PERPeru Lamas City Lama0.012083See
BRABrazil Parana Caucasian2.40.01202775See
ESPSpain, Castilla y Leon, Northwest,2.60.01201743See
ECUEcuador Mixed Ancestry0.01191173See
MEXMexico Jalisco Rural0.0119585See
MEXMexico Queretaro Rural0.011643See
VENVenezuela Colonia Tovar0.011686See
MEXMexico Veracruz Rural0.0111539See
MEXMexico Queretaro, Queretaro city0.011145See
ESPSpain Minorca0.011094See
PRTPortugal North0.011046See
PRTPortugal Center pop 20.0110562See
PRTPortugal Viana do Castelo0.0110706See
PRTPortugal Porto0.01107937See
MEXMexico Campeche Rural0.010647See
MEXMexico Aguascalientes state0.010595See
ALBAlbania pop 22.10.0104432See
ITAItaly East Sicily2.00.010050See
ARGArgentina Corrientes1.90.0100155See
PRTPortugal Bragança0.0100301See
MYSMalaysia Negeri Sembilan Minangkabau0.010034See
GBRUnited Kingdom pop 20.0100101See
MNGMongolia Khalkha pop 20.0100202See
PRTPortugal South pop 20.01001021See
ITAItaly South Campania Region2.00.01001089See
ARGArgentina Buenos Aires1.90.0100466See
VENVenezuela Caracas Mestizo0.010050See
PAKPakistan Mixed Sindhi0.0100101See
TTOTrinidad South Asian0.010087See
MEXMexico Quintana Roo Rural0.010050See
MEXMexico Oaxaca, Oaxaca city0.0099151See
MEXMexico Sinaloa, Culiacán0.0097103See
MEXMexico Tlaxcala Rural0.0096830See
GBRUnited Kingdom South West0.0096163See
INDIndia sub-Himalayan West Bengal Kami1.90.0095158See
MEXMexico Chiapas, Tuxtla Gutierrez0.009452See
IRQIraq Erbil1.90.0094372See
MMRMyanmar Shan1.90.009354See
MEXMexico Guanajuato Rural0.0092162See
ECUEcuador Andes Mixed Ancestry0.0091824See
MEXMexico Nuevo Leon Rural0.0091439See
MKDMacedonia pop 40.0090216See
ITAItaly North Pavia pop 21.80.00902416See
PRTPortugal Aveiro0.00905933See
FRAFrance Lyon1.80.00894813See
MEXMexico Veracruz, Cordoba0.008956See
MEXMexico Coahuila, Torreon0.0088396See
MEXMexico Michoacan Rural0.0086348See
MEXMexico Sinaloa Capomos Mayo Yoremes0.008360See
MEXMexico Veracruz, Orizaba0.008360See
IRNIran Royan Cord Blood Bank1.70.008015600See
ARGArgentina Cuyo Region1.60.0080420See
ESPSpain Murcia0.0080173See
PRTAzores Terceira Island0.0080130See
ENGEngland North West Mixed pop 21.60.0079379See
MEXMexico Yucatan, Merida0.0077192See
IRNIran pop 40.0076855See
MEXMexico Sonora Rural0.0076197See
FRAFrance Bordeaux1.50.0073990See
BOLBolivia Quechua0.007269See
MEXMexico Puebla Rural0.0072833See
MEXMexico Tabasco Rural0.0070142See
MEXMexico Tapachula, Chiapas Mestizo Population1.40.007072See
ARMArmenia living in Karabakh0.0070445See
PAKPakistan Kalash0.007069See
PERPeru Arequipa Mestizo1.40.0070168See
MEXMexico Michoacan Tarasco1.50.0070130See
CUBCuba Mixed0.007078See
PRTPortugal Braga0.00701971See
BGDBangladesh Dhaka Bangalee0.0070141See
MEXMexico Guerrero state0.0069144See
MEXMexico Coahuila Rural0.0069216See
CZECzech Republic Kurd1.40.006874See
FRAFrance Grenoble1.30.00671000See
MEXMexico Mexico City North0.0066751See
MEXMexico Nuevo Leon, Monterrey city0.0066226See
MEXMexico Mexico City Center0.0065152See
MEXMexico Mexico City East0.006379See
FRAFrance Marseille1.20.00621000See
GRCGreece pop 70.006111250See
ARGArgentina Buenos Aires pop 21.20.00601216See
FRAFrance Grenoble, Nantes and Rennes0.00606094See
AUSAustralia West Caucasian1.10.0060891See
ESPSpain Ibiza0.006088See
ROMRomania pop 31.20.00581469See
MEXMexico San Luis Potosi Rural0.005787See
MEXMexico Mestizo pop 40.0056269See
ENGEngland Lancaster1.10.0055545See
ITAItaly pop 61.10.0054184See
FRAFrance Rennes pop 41.00.00521000See
RUSRussia Northwest pop 20.90.0050346See
ARMArmenia combined Regions0.0050100See
ESPSpain Majorcans Jews0.0050103See
CHLChile Santiago0.0049920See
MKDMacedonia MBMDR - Macedonian0.90.00431283See
ALBAlbanian Kosovo0.0042120See
BIHBosnia and Herzegovina pop 20.80.0042120See
BRABrazil Curitiba-Parana Mixed0.0041264See
ARGArgentina La Plata1.00.0040100See
GRCGreece North0.0040500See
USAUSA Caucasian Bethesda0.80.0040307See
TURTurkey pop 50.0040142See
USAUSA OPTN Caucasian0.00408525See
MYSMalaysia pop 20.004062See
GTMGuatemala, Guatemala City Mixed Ancestry0.80.0039127See
MEXMexico Zacatecas Rural0.0037266See
RUSRussia Northwest0.70.00351011See
MEXMexico Michoacan, Morelia0.0033150See
ESPSpain Majorca0.0030407See
TWNTaiwan Minnan pop 20.00307137See
TWNTaiwan Chinese immigrants from South China0.0030172See
MKDMacedonia pop 30.0030172See
ENGEngland Manchester0.60.00301640See
ENGEngland London Ashkenazi Jews0.0030500See
ENGEngland Sheffield0.60.00304755See
ENGEngland Liverpool0.60.00301343See
ARMArmenia Yerevan0.0030445See
WALWales pop 20.60.003039979See
INDIndia North pop 30.0030587See
POLPoland pop 30.50.00262907See
ENGEngland Leeds0.50.00255024See
ENGEngland Newcastle0.50.00252739See
SRBSerbia pop 30.50.00231992See
SWESweden pop 40.40.0021966See
SVKSlovakia pop 20.00204234See
RUSRussia Moscow0.00202650See
RUSRussia South Ural Russian0.50.0020207See
ARMArmenia Ghegharkunik0.0020242See
ARMArmenia living in USA0.0020233See
SRBSerbia Vojvodina0.50.0020400See
USAUSA OPTN Asian0.0020261See
IRLIreland South pop 20.001717624See
INDIndia North Gujarat0.30.0015338See
NORNorway ethnic Norwegians0.30.00134510See
RUSRussia Moscow Pop 20.30.00122000See
ARMArmenia living in Lebanon0.0010368See
MYSMalaysia pop 30.00101445See
RUSRussia Samara Region0.00102500See
CHNChina Shandong Province0.10.00107418See
CHNChina Shanghai0.000426266See
SAUSaudi Arabia0.00.000018See
PAKPakistan Karachi Parsi0.000091See
CHNChina Jiangsu Province0.000020248See
CHNChina Guangdong Province0.00.0000403See
MYSMalaysia Perak and Johor Banjar Bugis Jawa0.000094See
MYSMalaysia Perak Rawa0.000023See
FRAFrance Rennes pop 30.0000200See
MEXMexico Nahuas0.000072See
TWNTaiwan Chinese immigrants from Middle China0.0000211See
TWNTaiwan Chinese immigrants from North China0.0000152See
TWNTaiwan Aborigine0.0000111See
TWNTaiwan Hakka pop 20.0000714See
BRABrazil Parana Oriental0.00.000033See
CHNChina North Han0.0000105See
CHNChina Harbin Manchu0.0000172See
CHNChina Harbin Korean0.0000201See
JPNJapan Hyogo Osaka and Nagano0.0000195See
PAKPakistan Mixed Pathan0.0000100See
PAKPakistan Burusho0.000092See
KORSouth Korea pop 10.0000324See
ITAItaly North pop 30.00.000097See
ARGArgentina Chiriguano0.00.000054See
ARGArgentina Salta Wichi pop 20.00.000019See
RUSRussia Nenet Mixed0.000055See
RUSRussia Arkhangelsk Pomor0.000063See
RUSRussia Murmansk Saomi Mixed0.000070See
GBRUnited Kingdom Orkney0.000088See
MEXMexico Quintana Roo, Cancun0.000048See
ECUEcuador Amazonia Mixed Ancestry0.000039See
MEXMexico Mexico City South0.000052See
MEXMexico Mexico City West0.000033See
MEXMexico Tabasco, Villahermosa0.000082See
MEXMexico Morelos, Cuernavaca0.000082See
RUSRussia Northwest pop 30.00.0000100See
RUSRussia South Ural Bashkir0.00.0000146See
RUSRussia South Ural Tatar0.00.0000135See
BIHBosnia and Herzegovina0.0000134See
CHNChina Shaanxi Province Han0.000010000See
THAThailand pop 40.000016807See
MEXMexico Coahuila, Saltillo0.000072See
MEXMexico Zacatecas, Fresnillo0.0000103See
MEXMexico Sonora, Hermosillo0.000099See
MEXMexico Veracruz, Poza Rica0.000045See
MEXMexico San Luis Potosi, San Luis Potosi city0.000030See
MEXMexico Jalisco, Tonala0.000035See
MEXMexico Guanajuato, Guanajuato city0.000022See
MEXMexico Morelos Rural0.000030See

Frequency data at lower resolution for this allele can be found in links below

Allele  Number of Populations 


* Allele Frequency: Total number of copies of the allele in the population sample (Alleles / 2n) in decimal format.
   Important: This field has been expanded to four decimals to better represent frequencies of large datasets (e.g. where sample size > 1000 individuals)
* Phenotype Frequency: Percentage of individuals who have the allele or gene (Individuals / n).
* Allele Frequencies shown in green were calculated from Phenotype Frequencies assuming Hardy-Weinberg proportions.

¹ IMGT/HLA Database - For more details of the allele.
² Distribution - Graphical distribution of the allele.
³ Haplotype Association - Find HLA haplotypes with this allele.
ª Notes - See notes for ambiguous combinations of alleles.


Allele frequency net database (AFND) 2020 update: gold-standard data classification, open access genotype data and new query tools
Gonzalez-Galarza FF, McCabe A, Santos EJ, Jones J, Takeshita LY, Ortega-Rivera ND, Del Cid-Pavon GM, Ramsbottom K, Ghattaoraya GS, Alfirevic A, Middleton D and Jones AR Nucleic Acid Research 2020, 48:D783-8.
Liverpool, U.K.

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