Allele Frequencies in World Populations

HLA Database » Allele Report

The list below shows all populations in AFND that contains the allele. If an allele has an entry with a lower resolution this will be shown at the end.



Allele reported 285 time(s) and present in 122 population(s).

Population Phenotype
Frequency (%)
Distribution² Haplotype³
JPNJapan Hyogo Osaka and Nagano0.0970195See
BRABrazil Parana Japanese18.00.0938192See
JPNJapan pop 20.0890916See
JPNJapan Tohoku Region0.0850322See
JPNJapan pop 1116.10.084062See
JPNJapan Hyogo15.60.078032See
JPNJapan Kyoto and Osaka0.0700165See
KORSouth Korea pop 10.0690324See
JPNJapan Aichi13.00.065050See
KORSouth Korea pop 80.05907096See
MNGMongolia Khalkha pop 20.0550202See
MNGMongolia Khalkha0.0500200See
CHNChina Harbin Manchu0.0440172See
TWNTaiwan Chinese immigrants from South China0.0430172See
RUSRussia Transbaikal Territory Buryats9.00.0430150See
CHNChina Wuhan7.50.0410121See
RUSRussia Nenet Mixed0.040055See
MNGMongolia Oold0.0390104See
TWNTaiwan Minnan and Hakka0.0390190See
CHNChina Shandong Province Linqu County7.30.0371139See
CHNChina Jiangsu Province0.037020248See
TWNTaiwan Chinese immigrants from North China0.0360152See
CHNChina Shanghai0.035026266See
CHNChina Harbin Korean0.0330201See
CHNChina Yunnan Province Han pop 20.0320129See
VNMVietnam Hanoi0.030050See
CHNChina Shandong Province5.80.02907418See
CHNChina Shaanxi Province Han0.029010000See
USAUSA OPTN Asian0.0280261See
TWNTaiwan Minnan pop 20.02507137See
TWNTaiwan Chinese immigrants from Middle China0.0240211See
MNGMongolia Tarialan Khoton0.024085See
MNGMongolia Tsaatan0.0210144See
CHNChina Guangdong Province4.00.0202403See
ESPSpain North Cabuerniga0.019095See
CHNChina Yunnan Province Naxi0.0180118See
TWNTaiwan Hakka pop 20.0160714See
BRABrazil Parana Oriental3.00.015033See
INDIndia Kerala Malabar Muslim0.015034See
GBRUnited Kingdom Central0.0150135See
THAThailand pop 40.014016807See
GBRUnited Kingdom East0.0124163See
MNGMongolia Ulaanbaatar Khalkha0.012041See
RUSRussia Tatars0.0098355See
GBRUnited Kingdom North0.0092330See
RUSRussia, South Ural, Chelyabinsk region, Nagaybaks1.80.0090112See
MEXMexico Sinaloa Mestizo0.009056See
BRABrazil Curitiba-Parana Mixed0.0082264See
GRCGreece pop31.60.0080246See
RUSRussia South Ural Bashkir1.40.0070146See
CZECzech Republic Kurd1.40.006874See
GBRUnited Kingdom South West0.0064163See
GBRUnited Kingdom Orkney0.006088See
RUSRussia Chuvash0.006082See
TWNTaiwan Aborigine0.0050111See
BRABrazil Sao Paulo Mixed0.10.0050239See
ESPSpain Minorca0.005094See
MEXMexico Sinaloa, Culiacán0.0049103See
PRTAzores Terceira Island0.0040130See
TURTurkey pop 50.0040142See
BIHBosnia and Herzegovina0.0037134See
ALBAlbania pop 20.70.0035432See
DEUGermany Essen0.60.0030174See
IRQIraq Erbil0.50.0027372See
ARMArmenia Ghegharkunik0.0020242See
MYSMalaysia pop 30.00201445See
RUSRussia Northwest pop 20.30.0020346See
MEXMexico Mestizo pop 40.0019269See
ESPSpain Sevilla0.40.0018278See
RUSRussia Northwest0.30.00151011See
BRABrazil REDOME Sao Paulo0.0014800809See
BRABrazil South East Cord Blood0.001411409See
BRABrazil REDOME Mato Grosso do Sul0.001295667See
BRABrazil REDOME Parana0.0011341639See
SRBSerbia Vojvodina0.20.0010400See
BRABrazil Sao Paulo Bauru Mixed0.00103542See
GRCGreece North0.0010500See
PRTPortugal Center pop 20.0010562See
ARGArgentina Buenos Aires pop 20.30.00101216See
WALWales pop 20.00.001039979See
SWESweden pop 40.20.0010966See
ROMRomania pop 30.20.00101469See
IRNIran Royan Cord Blood Bank0.20.001015600See
RUSRussia Samara Region0.00102500See
PRTPortugal Guarda0.0010797See
MEXMexico Puebla, Puebla city0.00081994See
BRABrazil REDOME Federal District0.000629549See
IRNIran pop 40.0006855See
MEXMexico Puebla Rural0.0006833See
GRCGreece pop 70.000611250See
BRABrazil Para Cord Blood Unit0.00.0006841See
FRAFrance Rennes pop 40.10.00051000See
ITAItaly South Campania Region0.10.00051089See
BRABrazil REDOME Amazonas0.000424129See
SVKSlovakia pop 20.00034234See
SRBSerbia pop 30.10.00031992See
BRABrazil Para State0.00.00035000See
BRABrazil REDOME Alagoas0.000325349See
BRABrazil REDOME Mato Grosso0.000334649See
BRABrazil REDOME Goias0.000288574See
BRABrazil REDOME Maranhao0.000210180See
BRABrazil REDOME Rio de Janeiro0.0002139322See
BRABrazil REDOME Minas Gerais0.0002211275See
BRABrazil REDOME Para0.000272637See
BRABrazil REDOME Rondonia0.000254396See
BRABrazil REDOME Santa Catarina0.0002106673See
BRABrazil REDOME Sergipe0.00027321See
BRABrazil REDOME Tocantins0.000220692See
NORNorway ethnic Norwegians0.00.00024510See
BRABrazil REDOME Rio Grande do Norte0.000146603See
BRABrazil REDOME Paraiba0.000143868See
BRABrazil REDOME Rio Grande do Sul0.0001241329See
BRABrazil REDOME Roraima0.00014140See
BRABrazil REDOME Espirito Santo0.000188485See
BRABrazil REDOME Amapa0.000117864See
BRABrazil REDOME Bahia0.000147399See
ISRIsrael Jews pop 20.00.000123000See
PRTPortugal South pop 20.00001021See
PAKPakistan Karachi Parsi0.000091See
INDIndia Kerala Hindu Namboothiri0.000040See
HRVCroatia pop 20.0000100See
MYSMalaysia pop 20.000062See
ARGArgentina Cuyo Region0.00.0000420See
MARMorocco Casablanca0.0000100See
SAUSaudi Arabia pop 20.0000383See
USAUSA OPTN African American0.00001510See
USAUSA OPTN Hispanic0.00001580See
USAUSA OPTN Caucasian0.00008525See
PRTPortugal Leiria0.00001847See
PRTPortugal Lisbon0.000017420See
PRTPortugal Portalegre0.00001254See
PRTPortugal Porto0.00007937See
PRTPortugal Santarem0.00003865See
PRTPortugal Setubal0.00005268See
PRTPortugal Viana do Castelo0.0000706See
PRTPortugal Vila Real0.00001167See
PRTPortugal Viseu0.00002915See
PRTMadeira pop 30.0000538See
PRTPortugal Aveiro0.00005933See
PRTPortugal Beja0.0000699See
PRTPortugal Braga0.00001971See
PRTPortugal Bragança0.0000301See
PRTPortugal Castelo Branco0.0000327See
PRTPortugal Coimbra0.00005057See
PRTPortugal Evora0.0000737See
PRTPortugal Faro0.00001242See
BRABrazil REDOME Ceara0.0000101217See
RUSRussia South Ural Tatar0.00.0000135See
MARMorocco pop 20.0000110See
RUSRussia Northwest pop 30.00.0000100See
BRABrazil Rio Grande do Norte Mestizo0.000012973See
ARGArgentina Corrientes0.00.0000155See
BRABrazil Piaui Mixed0.000021943See
MEXMexico Mexico City Mestizo0.0000121See
MEXMexico Puebla Mestizo0.000099See
AREUnited Arab Emirates pop 20.00.0000373See
RUSRussia South Ural Russian0.00.0000207See
RUSRussia Moscow0.00002650See
BRABrazil Parana Caucasian0.00.00002775See
BRABrazil Parana Cafuzo0.00.0000319See
BRABrazil Parana Mixed race0.00.0000186See
BRABrazil Parana Afro Brazilian0.00.000077See
RUSRussia Sakhalin Island Nivkhi0.000053See
INDIndia Kerala Hindu Pulaya0.000016See
INDIndia Kerala Hindu Nair0.000041See
INDIndia Kerala Syrian Christian0.000031See
INDIndia Kerala Hindu Ezhava0.000024See
CHNChina North Han0.0000105See
MKDMacedonia pop 40.0000216See
USAUSA Caucasian Bethesda0.00.0000307See
USAUSA African American Bethesda0.00.0000187See
TTOTrinidad African0.000067See
TTOTrinidad South Asian0.000087See
ITAItaly Bergamo0.00.0000101See
USAUSA South Texas Hispanic0.0000194See
PAKPakistan Baloch0.000066See
PAKPakistan Brahui0.0000104See
PAKPakistan Burusho0.000092See
PAKPakistan Kalash0.000069See
PAKPakistan Mixed Sindhi0.0000101See
ZAFSouth Africa Natal Zulu0.00.0000100See
ITAItaly Rome0.00.0000100See
ESPSpain Ibiza0.000088See
ESPSpain Majorcans Jews0.0000103See
ESPSpain Murcia0.0000173See
AUSAustralia West Caucasian0.00.0000891See
RUSRussia Arkhangelsk Pomor0.000063See
RUSRussia Murmansk Saomi Mixed0.000070See
PRTPortugal North0.000046See
ARGArgentina La Plata0.00.0000100See
ARGArgentina Chiriguano0.00.000054See
ARGArgentina Salta Wichi pop 20.00.000019See
ESPSpain Majorca0.0000407See
BRABrazil REDOME Pernambuco0.000092332See
BRABrazil REDOME Piaui0.000046140See
ECUEcuador Coast Mixed Ancestry0.0000238See
ECUEcuador Amazonia Mixed Ancestry0.000039See
ECUEcuador Andes Mixed Ancestry0.0000824See
ECUEcuador Mixed Ancestry0.00001173See
MEXMexico Tlaxcala, Tlaxcala city0.0000181See
MEXMexico Mexico City South0.000052See
MEXMexico Mexico City North0.0000751See
MEXMexico Mexico City East0.000079See
MEXMexico Mexico City Center0.0000152See
MEXMexico Hidalgo, Pachuca0.000041See
MEXMexico Veracruz, Xalapa0.0000187See
MEXMexico Veracruz, Veracruz city0.0000171See
MEXMexico Veracruz, Poza Rica0.000045See
MEXMexico Veracruz, Cordoba0.000056See
MEXMexico Veracruz, Orizaba0.000060See
MEXMexico Veracruz, Coatzacoalcos0.000055See
MEXMexico San Luis Potosi, San Luis Potosi city0.000030See
MEXMexico Tamaulipas, Ciudad Victoria0.000023See
MEXMexico Queretaro, Queretaro city0.000045See
MEXMexico Aguascalientes state0.000095See
MEXMexico Nuevo Leon, Monterrey city0.0000226See
MEXMexico Colima, Colima city0.000061See
MEXMexico Guanajuato, Leon0.000078See
MEXMexico Guanajuato, Guanajuato city0.000022See
MEXMexico Michoacan, Morelia0.0000150See
MEXMexico Jalisco, Zapopan0.0000168See
MEXMexico Jalisco, Tonala0.000035See
MEXMexico Jalisco, Tlaquepaque0.000039See
MEXMexico Jalisco, Tlajomulco0.000030See
MEXMexico Jalisco, Guadalajara city0.00001189See
MEXMexico Nayarit, Tepic0.000097See
MEXMexico Zacatecas, Fresnillo0.0000103See
MEXMexico Zacatecas, Zacatecas city0.000084See
MEXMexico Coahuila, Torreon0.0000396See
MEXMexico Coahuila, Saltillo0.000072See
MEXMexico Durango, Durango city0.0000153See
MEXMexico Chihuahua, Ciudad Juarez0.0000106See
MEXMexico Chihuahua Chihuahua City0.0000119See
ESPSpain, Castilla y Leon, Northwest,0.00.00001743See
MEXMexico Baja California, Tijuana0.000025See
MEXMexico Oaxaca Rural0.0000485See
MEXMexico Morelos Rural0.000030See
MEXMexico Tabasco Rural0.0000142See
MEXMexico Chiapas Rural0.0000121See
MEXMexico Campeche Rural0.000047See
MEXMexico Yucatan Rural0.0000132See
MEXMexico Quintana Roo Rural0.000050See
MEXMexico Quintana Roo, Cancun0.000048See
MEXMexico Mexico City West0.000033See
MEXMexico Yucatan, Merida0.0000192See
MEXMexico Campeche, Campeche city0.000034See
MEXMexico Chiapas, Tuxtla Gutierrez0.000052See
MEXMexico Tabasco, Villahermosa0.000082See
MEXMexico Morelos, Cuernavaca0.000082See
MEXMexico Oaxaca, Oaxaca city0.0000151See
MEXMexico Guerrero state0.0000144See
MEXMexico Sonora, Hermosillo0.000099See
MEXMexico Sonora, Ciudad Obregón0.0000143See
MEXMexico Baja California, La Paz0.000075See
MEXMexico Baja Californa, Mexicali0.0000100See
MEXMexico Baja California Rural0.000050See
MEXMexico Sonora Rural0.0000197See
MEXMexico Sinaloa Rural0.0000183See
MEXMexico Chihuahua Rural0.0000236See
MEXMexico Durango Rural0.0000326See
MEXMexico Coahuila Rural0.0000216See
MEXMexico Zacatecas Rural0.0000266See
MEXMexico Nayarit Rural0.000064See
MEXMexico Jalisco Rural0.0000585See
MEXMexico Michoacan Rural0.0000348See
MEXMexico Guanajuato Rural0.0000162See
MEXMexico Colima Rural0.000043See
MEXMexico Nuevo Leon Rural0.0000439See
MEXMexico Queretaro Rural0.000043See
MEXMexico Tamaulipas Rural0.0000125See
MEXMexico San Luis Potosi Rural0.000087See
MEXMexico Veracruz Rural0.0000539See
MEXMexico Hidalgo Rural0.000081See
MEXMexico Mexico City Metropolitan Area Rural0.0000150See
MEXMexico Tlaxcala Rural0.0000830See

Frequency data at lower resolution for this allele can be found in links below

Allele  Number of Populations 


* Allele Frequency: Total number of copies of the allele in the population sample (Alleles / 2n) in decimal format.
   Important: This field has been expanded to four decimals to better represent frequencies of large datasets (e.g. where sample size > 1000 individuals)
* Phenotype Frequency: Percentage of individuals who have the allele or gene (Individuals / n).
* Allele Frequencies shown in green were calculated from Phenotype Frequencies assuming Hardy-Weinberg proportions.

¹ IMGT/HLA Database - For more details of the allele.
² Distribution - Graphical distribution of the allele.
³ Haplotype Association - Find HLA haplotypes with this allele.
ª Notes - See notes for ambiguous combinations of alleles.


Allele frequency net database (AFND) 2020 update: gold-standard data classification, open access genotype data and new query tools
Gonzalez-Galarza FF, McCabe A, Santos EJ, Jones J, Takeshita LY, Ortega-Rivera ND, Del Cid-Pavon GM, Ramsbottom K, Ghattaoraya GS, Alfirevic A, Middleton D and Jones AR Nucleic Acid Research 2020, 48:D783-8.
Liverpool, U.K.

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