Allele Frequencies in World Populations

HLA Database Allele Report

The list below shows all populations in AFND that contains the allele. If an allele has an entry with a lower resolution this will be shown at the end.



Allele reported 159 time(s) and present in 113 population(s).

Population Phenotype
Frequency (%)
Distribution² Haplotype³
USAUSA Spain Ancestry0.1200279See
USAUSA Hawaii Okinawa0.1060106See
JPNJapan pop 30.08801018See
JPNJapan Central0.0770371See
JPNJapan pop 160.074918604See
JPNJapan pop 50.0700117See
KORSouth Korea pop 30.0590485See
USAUSA NMDP Korean0.057277584See
KORSouth Korea pop 100.05724128See
SGPSingapore Chinese Han0.052094See
CHNChina Jiangsu Province Han0.0488334See
CHNChina Guangzhou0.0450102See
TWNTaiwan Han Chinese0.0420504See
THAThailand pop 30.041049See
TWNTaiwan Minnan pop 17.80.0390102See
CHNChina Guangzhou Han0.0380106See
CHNChina Beijing0.038067See
TWNTaiwan Tzu Chi Cord Blood Bank0.0370710See
CHNChina Jiangsu Han0.03703238See
CHNChina Marrow Donor Registry0.0360600See
USAUSA Asian0.0360358See
CHNChina Yunnan Province Han0.0350101See
CHNChina Inner Mongolia Region0.0340102See
CHNChina North Han0.0330105See
USAUSA Asian pop 20.03281772See
CHNChina Yunnan Province Nu0.0320107See
SGPSingapore SGVP Chinese CHS0.032096See
TWNTaiwan Tzu Chi Morrow Donor Registry0.031346682See
DEUGermany DKMS - China minority0.03121282See
CHNChina Hubei Han6.20.03113732See
CHNChina Han HIV negative0.031072See
CHNChina Henan HIV negative0.031016See
USAUSA NMDP Chinese0.030499672See
CHNChina Beijing Shijiazhuang Tianjian Han0.0300618See
HKGHong Kong Chinese5.80.0300569See
HKGHong Kong Chinese BMDR0.02967595See
CHNChina Sichuan HIV negative0.029034See
TWNTaiwan Siraya5.90.029051See
TWNTaiwan pop 20.0280364See
TWNTaiwan Hakka5.50.027055See
HKGHong Kong Chinese cord blood registry0.02613892See
TWNTaiwan pop 30.0260212See
CHNChina Canton Han0.0250264See
CHNChina South Han0.0250284See
USAUSA NMDP Vietnamese0.024443540See
VNMVietnam Hanoi Kinh pop 20.0240170See
CHNChina Qinghai Province Hui0.0230110See
CHNChina Shanxi HIV negative0.023022See
RUSRussia Tuva pop 20.0220169See
CHNChina Guangxi Region Maonan0.0190108See
SGPSingapore Chinese3.40.0170149See
TWNTaiwan Thao3.30.017030See
MYSMalaysia Peninsular Chinese3.10.0155194See
CHNChina Guangdong Province Meizhou Han0.0150100See
CHNChina Tibet Region Tibetan0.0130158See
USAUSA San Diego2.60.0130496See
CHNChina Yunnan Bulang0.0130116See
SGPSingapore SGVP Malay MAS0.012089See
CHNChina Guizhou Province Shui0.0110153See
SGPSingapore Javaneses0.010051See
JPNJapan Hokkaido Ainu0.010050See
PHLPhilippines Ivatan2.00.010050See
TWNTaiwan Pazeh1.80.009055See
THAThailand Northeast pop 20.0090400See
IRNIran Saqqez-Baneh Kurds0.008360See
IRNIran Gorgan0.008064See
IRNIran Kurd pop 20.008060See
THAThailand Northeast0.008066See
CHNChina Yunnan Province Lisu0.0070111See
TWNTaiwan Tzu Chi Morrow Donor Registry Aborigine0.0064233See
INDIndia Mumbai Maratha0.006091See
USAUSA NMDP Filipino0.005350614See
IRNIran Tabriz Azeris0.005297See
NZLNew Zealand Maori with Admixed History1.00.0050105See
CHNChina Guizhou Province Bouyei0.0050109See
SGPSingapore Riau Malay0.0050132See
TWNTaiwan Bunun1.00.0050101See
PRTPortugal Azores Terceira Island0.90.0044130See
PRTAzores Terceira Island0.0040130See
USAUSA NMDP Southeast Asian0.003827978See
USAUSA NMDP Hawaiian or other Pacific Islander0.003411499See
MYSMalaysia Peninsular Malay0.50.0026951See
DEUGermany DKMS - Turkey minority0.00204856See
USAUSA San Francisco Caucasian0.0020220See
INDIndia Northeast UCBB0.30.0017296See
MEXMexico Mexico City Tlalpan0.30.0015330See
RUSRussia Karelia0.00081075See
DEUGermany DKMS - Croatia minority0.00052057See
ISRIsrael Kavkazi Jews0.00042840See
ISRIsrael USSR Jews0.000445681See
HRVCroatia pop 40.00034000See
USAUSA NMDP Middle Eastern or North Coast of Africa0.000370890See
USAUSA NMDP South Asian Indian0.0003185391See
INDIndia East UCBB0.00.00022403See
DEUGermany pop 80.000239689See
USAUSA Hispanic pop 20.00031999See
ISRIsrael USA Jews0.00026058See
POLPoland DKMS0.000120653See
USAUSA NMDP Hispanic South or Central American0.0001146714See
ISRIsrael Poland Jews0.000113871See
USAUSA NMDP Mexican or Chicano0.0001261235See
DEUGermany DKMS - German donors0.00013456066See
USAUSA NMDP European Caucasian0.00001242890See
USAUSA NMDP Caribean Hispanic0.0000115374See
USAUSA NMDP African American pop 20.0000416581See
ISRIsrael Morocco Jews0.000036718See
ISRIsrael Georgia Jews0.00004471See
ISRIsrael Druze0.00005914See
ISRIsrael Iraq Jews0.000013270See
NLDNetherlands Leiden0.00001305See
FRAFrance Grenoble, Nantes and Rennes0.00006094See
DEUGermany pop 60.00018862See
USAUSA Caucasian pop 40.00001070See
CHNChina Guizhou Province Miao pop 20.000085See
USAUSA African American pop 40.00002411See
MARMorocco Nador Metalsa pop 20.000073See
USAUSA Caucasian Bethesda0.00.0000307See
USAUSA African American Bethesda0.00.0000187See
USAUSA Philadelphia Caucasian0.00.0000141See
BFABurkina Faso Fulani0.000049See
BFABurkina Faso Mossi0.000053See
BFABurkina Faso Rimaibe0.000047See
ESPSpain Majorca and Minorca0.000090See
FRAFrance Corsica Island0.0000100See
ITAItaly Sardinia pop30.0000100See
TWNTaiwan Tsou0.00.000051See
TWNTaiwan Rukai0.00.000050See
TWNTaiwan Paiwan0.00.000051See
TWNTaiwan Ami0.00.000098See
TWNTaiwan Puyuma0.00.000050See
TWNTaiwan Tao0.00.000050See
TWNTaiwan Atayal0.00.0000106See
TWNTaiwan Taroko0.00.000055See
TWNTaiwan Saisiat0.00.000051See
BRABrazil Belo Horizonte Caucasian0.00.000095See
CUBCuba Mixed Race0.00.000042See
CUBCuba Caucasian0.00.000070See
MEXMexico Mestizo0.00.000041See
SCOScotland Orkney0.00.000099See
INDIndia West Bhil0.000050See
INDIndia Khandesh Region Pawra0.000050See
ZAFSouth Africa Natal Zulu0.00.0000100See
NIRIreland Northern0.00.00001000See
INDIndia West Coast Parsi0.000050See
MARMorocco Settat Chaouya0.00.000098See
USAUSA Caucasian pop 20.0000265See
USAUSA African American0.0000252See
USAUSA Hispanic0.0000234See
USAUSA North American Native0.0000187See
USAUSA San Antonio Caucasian0.0000222See
USAUSA Alaska Yupik0.0000252See
CZECzech Republic0.0000106See
SGPSingapore SGVP. Indian INS0.000086See

Frequency data at lower resolution for this allele can be found in links below

Allele  Number of Populations 


* Allele Frequency: Total number of copies of the allele in the population sample (Alleles / 2n) in decimal format.
   Important: This field has been expanded to four decimals to better represent frequencies of large datasets (e.g. where sample size > 1000 individuals)
* Phenotype Frequency: Percentage of individuals who have the allele or gene (Individuals / n).
* Allele Frequencies shown in green were calculated from Phenotype Frequencies assuming Hardy-Weinberg proportions.

¹ IMGT/HLA Database - For more details of the allele.
² Distribution - Graphical distribution of the allele.
³ Haplotype Association - Find HLA haplotypes with this allele.
ª Notes - See notes for ambiguous combinations of alleles.

Allele frequency net database (AFND) 2020 update: gold-standard data classification, open access genotype data and new query tools
Gonzalez-Galarza FF, McCabe A, Santos EJ, Jones J, Takeshita LY, Ortega-Rivera ND, Del Cid-Pavon GM, Ramsbottom K, Ghattaoraya GS, Alfirevic A, Middleton D and Jones AR Nucleic Acid Research 2020, 48:D783-8.
Liverpool, U.K.

Valid XHTML 1.0 Transitional