Allele Frequencies in World Populations

HLA Database » Allele Report

The list below shows all populations in AFND that contains the allele. If an allele has an entry with a lower resolution this will be shown at the end.



Allele reported 353 time(s) and present in 256 population(s).

Population Phenotype
Frequency (%)
Distribution² Haplotype³
MMRMyanmar Chin21.80.118255See
MMRMyanmar Kachin14.30.079463See
TWNTaiwan Aborigine0.0760111See
CHNChina Yunnan Province Naxi0.0730118See
INDIndia Kerala Kurichiya0.050010See
MMRMyanmar Mon9.40.046964See
MEXMexico Tamaulipas, Ciudad Victoria0.043523See
GEOGeorgia Kurds0.036030See
INDIndia Kerala Hindu Pulaya0.031016See
BRABrazil Parana Oriental6.10.030033See
ECUEcuador Amazonia Mixed Ancestry0.025639See
HRVCroatia pop 35.00.0250120See
INDIndia Kerala Hindu Namboothiri0.025040See
VENVenezuela Zulia Maracaibo Mixed0.025020See
INDIndia Kerala Hindu Nair0.024041See
MMRMyanmar Kayin4.50.022744See
ESPSpain Majorcans Jews0.0220103See
MNGMongolia Khalkha pop 20.0200202See
MYSMalaysia Perak Rawa0.020023See
MMRMyanmar Kayah3.60.018255See
SRBSerbia Vojvodina3.70.0180400See
MYSMalaysia pop 20.018062See
VENVenezuela Colonia Tovar0.017486See
ALBAlbanian Kosovo0.0167120See
JPNJapan Hyogo3.10.016032See
ESPSpain Murcia0.0160173See
POLPoland pop 33.10.01572907See
MEXMexico Nayarit Rural0.015664See
BRABrazil Belem Mixed3.00.0150100See
RUSRussia South Ural Tatar3.00.0150135See
RUSRussia Northwest pop 33.00.0150100See
INDIndia Kerala Malabar Muslim0.015034See
HRVCroatia pop 20.0150100See
JPNJapan Kyoto and Osaka0.0150165See
MEXMexico Jalisco, Tonala0.014335See
AUSAustralia West Caucasian2.80.0140891See
THAThailand pop 40.014016807See
CHNChina Guangdong Province2.70.0135403See
JPNJapan Tohoku Region0.0130322See
CHNChina Wuhan2.50.0130121See
ESPSpain North Cabuerniga0.013095See
RUSRussia Moscow Pop 22.60.01282000See
INDIndia sub-Himalayan West Bengal Kami2.50.0127158See
SVKSlovakia pop 20.01244234See
RUSRussia Moscow0.01202650See
DEUGermany Essen2.30.0120174See
ITAItaly Bergamo1.90.0120101See
SRBSerbia pop 32.30.01131992See
BIHBosnia and Herzegovina0.0111134See
RUSRussia Northwest pop 22.20.0110346See
PAKPakistan Karachi Parsi0.011091See
CHNChina Yunnan Province Han pop 20.0110129See
CZECzech Republic Romani pop 22.20.010946See
MMRMyanmar Bamar2.20.010946See
MEXMexico Campeche Rural0.010647See
ENGEngland North West Mixed pop 22.10.0106379See
MMRMyanmar Rakhine2.10.010448See
ROMRomania pop 32.10.01021469See
MYSMalaysia Sarawak Iban0.010051See
RUSRussia South Ural Russian1.90.0100207See
MEXMexico Puebla Mestizo0.010099See
JPNJapan Hyogo Osaka and Nagano0.0100195See
RUSRussia Murmansk Saomi Mixed0.010070See
ROMRomania pop 20.01006936See
FRAFrance Bordeaux2.00.0099990See
FRAFrance Marseille2.00.00971000See
MEXMexico Mexico City South0.009652See
MKDMacedonia MBMDR - Macedonian1.90.00941283See
MMRMyanmar Shan1.90.009354See
SWESweden pop 41.90.0093966See
MYSMalaysia Sabah Kadazan0.009057See
MYSMalaysia pop 30.00901445See
RUSRussia Samara Region0.00902500See
PRTPortugal Guarda0.0090797See
JPNJapan pop 20.0090916See
TWNTaiwan Chinese immigrants from South China0.0090172See
MEXMexico Veracruz, Coatzacoalcos0.008955See
ITAItaly North Pavia pop 30.0087685See
MEXMexico Veracruz, Veracruz city0.0087171See
FRAFrance Rennes pop 41.70.00831000See
FRAFrance Lyon1.60.00824813See
PRTPortugal North pop 20.00811801See
TWNTaiwan Minnan and Hakka0.0080190See
IRNIran pop 10.008064See
USAUSA OPTN Asian0.0080261See
FRAFrance Grenoble, Nantes and Rennes0.00806094See
TWNTaiwan Hakka pop 20.0080714See
TWNTaiwan Minnan pop 20.00807137See
ARGArgentina Buenos Aires pop 21.60.00801216See
FRAFrance Grenoble1.50.00771000See
MEXMexico Sonora Rural0.0076197See
RUSRussia Northwest1.50.00751011See
ESPSpain Majorca0.0070407See
USAUSA OPTN Caucasian0.00708525See
RUSRussia Tatars0.0070355See
ARMArmenia Shirak0.007076See
MEXMexico Tabasco Rural0.0070142See
MEXMexico Tapachula, Chiapas Mestizo Population1.40.007072See
MEXMexico Guerrero state0.0069144See
MEXMexico Mexico City Center0.0065152See
MEXMexico Guanajuato, Leon0.006478See
BRABrazil Rio Grande do Sul Caucasoid0.00604428See
PRTPortugal Leiria0.00601847See
RUSRussia Chuvash0.006082See
BRABrazil Parana Afro Brazilian1.30.006077See
GRCGreece pop 70.005711250See
MEXMexico Mestizo pop 40.0056269See
BRABrazil REDOME Rio Grande do Sul0.0056241329See
ECUEcuador Mixed Ancestry0.00551173See
COLColombia Barranquilla0.0055188See
ENGEngland Lancaster1.10.0055545See
BRABrazil Paraná Caucasian1.10.0055641See
BRABrazil REDOME Santa Catarina0.0053106673See
NORNorway ethnic Norwegians1.00.00524510See
ITAItaly Lombardy1.00.0050674See
PRTPortugal Viseu0.00502915See
CHNChina Shanghai0.005026266See
ENGEngland Sheffield1.00.00504755See
PRTPortugal Evora0.0050737See
PRTPortugal Aveiro0.00505933See
ITAItaly North Pavia pop 21.00.00502416See
PRTPortugal Castelo Branco0.0050327See
FRAFrance Reims0.0050102See
VENVenezuela Valencia and Maracaibo Caracus Mixed0.005096See
MYSMalaysia Perak and Johor Banjar Bugis Jawa0.005094See
ITAItaly South Campania Region1.00.00501089See
BRABrazil Parana Caucasian1.00.00502775See
BRABrazil Parana Cafuzo0.90.0050319See
BRABrazil Pernambuco Mixed0.0050101See
TWNTaiwan Chinese immigrants from Middle China0.0050211See
USAUSA African American Bethesda1.10.0050187See
ITAItaly Rome1.00.0050100See
ESPSpain Minorca0.005094See
BRABrazil Sao Paulo Mixed0.10.0050239See
SENSenegal Dakar0.90.0050112See
MEXMexico Baja Californa, Mexicali0.0050100See
ECUEcuador Andes Mixed Ancestry0.0049824See
BRABrazil REDOME Parana0.0047341639See
IRNIran pop 40.0047855See
ENGEngland Leeds0.90.00455024See
INDIndia North Gujarat0.90.0044338See
CHLChile Santiago0.0043920See
BRABrazil REDOME Maranhao0.004310180See
ECUEcuador Coast Mixed Ancestry0.0042238See
BRABrazil Curitiba-Parana Mixed0.0041264See
MEXMexico Oaxaca Rural0.0041485See
RUSRussia, South Ural, Chelyabinsk region, Nagaybaks0.90.0040112See
SVNSlovenia pop 30.80.0040130See
BRABrazil REDOME Amapa0.004017864See
PRTPortugal Setubal0.00405268See
PRTPortugal Viana do Castelo0.0040706See
PRTPortugal Vila Real0.00401167See
KORSouth Korea pop 80.00407096See
CHNChina Shaanxi Province Han0.004010000See
WALWales pop 20.80.004039979See
PRTPortugal South pop 20.00401021See
ENGEngland London Ashkenazi Jews0.0040500See
PRTPortugal Beja0.0040699See
PRTPortugal Braga0.00401971See
PRTPortugal Porto0.00407937See
PRTPortugal Lisbon0.004017420See
PRTAzores Terceira Island0.0040130See
GRCGreece North0.0040500See
SWESweden Uppsala0.80.0040300See
MKDMacedonia MBMDR - Albanian0.80.0039128See
GTMGuatemala, Guatemala City Mixed Ancestry0.80.0039127See
BRABrazil REDOME Sao Paulo0.0037800809See
ESPSpain, Castilla y Leon, Northwest,0.90.00371743See
BRABrazil REDOME Piaui0.003646140See
BRABrazil REDOME Alagoas0.003625349See
BRABrazil Para Cord Blood Unit0.00.0036841See
ENGEngland Newcastle0.70.00352739See
ENGEngland Manchester0.70.00351640See
BRABrazil REDOME Para0.003472637See
BRABrazil REDOME Tocantins0.003420692See
MEXMexico Oaxaca, Oaxaca city0.0033151See
BRABrazil REDOME Mato Grosso do Sul0.003395667See
BRABrazil REDOME Espirito Santo0.003388485See
BRABrazil REDOME Rio de Janeiro0.0032139322See
BRABrazil South East Cord Blood0.003211409See
MEXMexico Durango, Durango city0.0032153See
BRABrazil REDOME Rondonia0.003154396See
BRABrazil REDOME Federal District0.003129549See
IRLIreland South pop 20.003117624See
BRABrazil REDOME Bahia0.003047399See
BRABrazil Piaui Mixed0.003021943See
BRABrazil South Ribeirao Preto0.0030184See
RUSRussia South Ural Bashkir0.70.0030146See
USAUSA OPTN Hispanic0.00301580See
AREUnited Arab Emirates pop 20.50.0030373See
ARMArmenia living in Lebanon0.0030368See
GAZGaza Palestinians0.0030165See
BRABrazil Rio Grande do Sul Mixed0.0030324See
BRABrazil Sao Paulo Bauru Mixed0.00303542See
CHNChina Jiangsu Province0.003020248See
PRTPortugal Santarem0.00303865See
PRTPortugal Faro0.00301242See
PRTPortugal Bragança0.0030301See
PRTPortugal Coimbra0.00305057See
CHNChina Shandong Province0.50.00307418See
SAUSaudi Arabia pop 20.0030383See
CHNChina Harbin Manchu0.0030172See
ISRIsrael Jews pop 20.60.003023000See
MKDMacedonia pop 30.0030172See
ARGArgentina Buenos Aires0.60.0030466See
BRABrazil Para State0.30.00305000See
BRABrazil REDOME Pernambuco0.002992332See
BRABrazil REDOME Acre0.0029859See
BRABrazil REDOME Mato Grosso0.002934649See
MEXMexico Veracruz Rural0.0028539See
ITAItaly pop 60.50.0027184See
BRABrazil REDOME Roraima0.00274140See
BRABrazil REDOME Paraiba0.002643868See
BRABrazil REDOME Goias0.002688574See
BRABrazil REDOME Amazonas0.002624129See
BRABrazil REDOME Minas Gerais0.0025211275See
MEXMexico Jalisco, Guadalajara city0.00251189See
MEXMexico Coahuila Rural0.0023216See
BRABrazil REDOME Ceara0.0023101217See
BRABrazil REDOME Sergipe0.00237321See
ALBAlbania pop 20.50.0023432See
MEXMexico Chihuahua Rural0.0021236See
ARMArmenia living in USA0.0020233See
BRABrazil REDOME Rio Grande do Norte0.002046603See
ARMArmenia Yerevan0.0020445See
IRNIran Royan Cord Blood Bank0.40.002015600See
BRABrazil Rio Grande do Norte Mestizo0.002012973See
MKDMacedonia pop 40.0020216See
PRTPortugal Center pop 20.0020562See
TURTurkey pop 20.0020228See
BRABrazil Minas Gerais State Mixed0.40.00201000See
ARGArgentina Cuyo Region0.50.0020420See
ENGEngland Liverpool0.40.00201343See
MEXMexico Zacatecas Rural0.0019266See
MEXMexico Tlaxcala Rural0.0018830See
ESPSpain Sevilla0.40.0018278See
MEXMexico Puebla, Puebla city0.00151994See
MEXMexico Michoacan Rural0.0014348See
INDIndia North pop 30.0010587See
PRTMadeira pop 30.0010538See
USAUSA OPTN African American0.00101510See
PRTPortugal Portalegre0.00101254See
MEXMexico Jalisco Rural0.0009585See
MEXMexico Mexico City North0.0007751See
MEXMexico Mexico City East0.000079See
MEXMexico Hidalgo, Pachuca0.000041See
MEXMexico Veracruz, Xalapa0.0000187See
MEXMexico Tlaxcala, Tlaxcala city0.0000181See
MEXMexico Veracruz, Poza Rica0.000045See
MEXMexico Veracruz, Cordoba0.000056See
MEXMexico Veracruz, Orizaba0.000060See
MEXMexico Queretaro, Queretaro city0.000045See
MEXMexico Aguascalientes state0.000095See
MEXMexico Nuevo Leon, Monterrey city0.0000226See
MEXMexico Colima, Colima city0.000061See
MEXMexico Quintana Roo, Cancun0.000048See
MEXMexico Mexico City West0.000033See
MEXMexico Yucatan, Merida0.0000192See
MEXMexico Campeche, Campeche city0.000034See
MEXMexico Chiapas, Tuxtla Gutierrez0.000052See
MEXMexico Tabasco, Villahermosa0.000082See
MEXMexico Morelos, Cuernavaca0.000082See
TZATanzania Dodoma Kongwa0.0000212See
MEXMexico Mexico City Mestizo0.0000121See
MEXMexico Sinaloa Mestizo0.000056See
MARMorocco pop 20.0000110See
ARGArgentina Corrientes0.00.0000155See
MYSMalaysia Negeri Sembilan Minangkabau0.000034See
VNMVietnam Hanoi0.000050See
MARMorocco Casablanca0.0000100See
INDIndia Kerala Kanikkar0.000022See
INDIndia Kerala Kattunaikka0.000017See
INDIndia Kerala Kuruma0.000015See
INDIndia Kerala Syrian Christian0.000031See
INDIndia Kerala Hindu Ezhava0.000024See
INDIndia Kerala Paniya0.000010See
INDIndia Kerala Malapandaram0.000010See
INDIndia Kerala Adiya0.000021See
USAUSA Caucasian Bethesda0.00.0000307See
TURTurkey pop 50.0000142See
MEXMexico Nahuas0.000072See
MEXMexico Huasteca Region Teenek0.000055See
MEXMexico Mayan Pop 30.000066See
TWNTaiwan Chinese immigrants from North China0.0000152See
CHNChina North Han0.0000105See
BFABurkina Faso Fulani0.000049See
BFABurkina Faso Mossi0.000053See
BFABurkina Faso Rimaibe0.000047See
CHNChina Harbin Korean0.0000201See
BRABrazil Parana Mixed race0.00.0000186See
ARGArgentina Chiriguano0.00.000054See
ARGArgentina Salta Wichi pop 20.00.000019See
ESPSpain Ibiza0.000088See
PRTPortugal North0.000046See
ARGArgentina La Plata0.00.0000100See
ZAFSouth Africa Natal Zulu0.00.0000100See
RUSRussia Nenet Mixed0.000055See
RUSRussia Arkhangelsk Pomor0.000063See
KORSouth Korea pop 10.0000324See
VENVenezuela Caracas Mestizo0.000050See
ITAItaly North pop 30.00.000097See
PAKPakistan Baloch0.000066See
PAKPakistan Brahui0.0000104See
PAKPakistan Burusho0.000092See
PAKPakistan Kalash0.000069See
PAKPakistan Mixed Pathan0.0000100See
PAKPakistan Mixed Sindhi0.0000101See
MEXMexico Hidalgo Rural0.000081See
MEXMexico Mexico City Metropolitan Area Rural0.0000150See
MEXMexico Guanajuato Rural0.0000162See
MEXMexico Colima Rural0.000043See
MEXMexico Nuevo Leon Rural0.0000439See
MEXMexico Queretaro Rural0.000043See
MEXMexico Tamaulipas Rural0.0000125See
MEXMexico San Luis Potosi Rural0.000087See
MEXMexico Durango Rural0.0000326See
MEXMexico Baja California Rural0.000050See
MEXMexico Sinaloa Rural0.0000183See
MEXMexico Nayarit, Tepic0.000097See
MEXMexico Zacatecas, Fresnillo0.0000103See
MEXMexico Zacatecas, Zacatecas city0.000084See
MEXMexico Coahuila, Torreon0.0000396See
MEXMexico Coahuila, Saltillo0.000072See
MEXMexico Chihuahua, Ciudad Juarez0.0000106See
MEXMexico Chihuahua Chihuahua City0.0000119See
MEXMexico Sinaloa, Culiacán0.0000103See
MEXMexico Sonora, Hermosillo0.000099See
MEXMexico Sonora, Ciudad Obregón0.0000143See
MEXMexico Baja California, La Paz0.000075See
MEXMexico Guanajuato, Guanajuato city0.000022See
MEXMexico Michoacan, Morelia0.0000150See
MEXMexico Jalisco, Zapopan0.0000168See
MEXMexico San Luis Potosi, San Luis Potosi city0.000030See
MEXMexico Jalisco, Tlaquepaque0.000039See
MEXMexico Jalisco, Tlajomulco0.000030See
MEXMexico Puebla Rural0.0000833See
MEXMexico Morelos Rural0.000030See
MEXMexico Chiapas Rural0.0000121See
MEXMexico Yucatan Rural0.0000132See
MEXMexico Quintana Roo Rural0.000050See
MEXMexico Baja California, Tijuana0.000025See

Frequency data at lower resolution for this allele can be found in links below

Allele  Number of Populations 


* Allele Frequency: Total number of copies of the allele in the population sample (Alleles / 2n) in decimal format.
   Important: This field has been expanded to four decimals to better represent frequencies of large datasets (e.g. where sample size > 1000 individuals)
* Phenotype Frequency: Percentage of individuals who have the allele or gene (Individuals / n).
* Allele Frequencies shown in green were calculated from Phenotype Frequencies assuming Hardy-Weinberg proportions.

¹ IMGT/HLA Database - For more details of the allele.
² Distribution - Graphical distribution of the allele.
³ Haplotype Association - Find HLA haplotypes with this allele.
ª Notes - See notes for ambiguous combinations of alleles.


Allele frequency net database (AFND) 2020 update: gold-standard data classification, open access genotype data and new query tools
Gonzalez-Galarza FF, McCabe A, Santos EJ, Jones J, Takeshita LY, Ortega-Rivera ND, Del Cid-Pavon GM, Ramsbottom K, Ghattaoraya GS, Alfirevic A, Middleton D and Jones AR Nucleic Acid Research 2020, 48:D783-8.
Liverpool, U.K.

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