Allele Frequencies in World Populations

HLA Database » Allele Report

The list below shows all populations in AFND that contains the allele. If an allele has an entry with a lower resolution this will be shown at the end.



Allele reported 261 time(s) and present in 223 population(s).

Population Phenotype
Frequency (%)
Distribution² Haplotype³
AUSAustralia Kimberly Aborigine0.355041See
PNGPapua New Guinea Madang0.346065See
PNGPapua New Guinea East New Britain Rabaul0.316060See
PNGPapua New Guinea Eastern Highlands Goroka Asaro0.229057See
PNGPapua New Guinea West Schrader Ranges Haruai0.209055See
TWNTaiwan Ami37.80.204098See
NCLNew Caledonia0.192065See
AUSAustralia Groote Eylandt Aborigine0.180075See
PNGPapua New Guinea Wanigela Keapara0.167066See
AUSAustralia Cape York Peninsula Aborigine0.1650103See
PNGPapua New Guinea Karimui Plateau Pawaia0.156080See
PNGPapua New Guinea Wosera Abelam0.1160131See
AUSAustralia Yuendumu Aborigine0.1140191See
CHNChina Yunnan Province Lisu0.0940111See
TWNTaiwan Tzu Chi Morrow Donor Registry Aborigine0.0794233See
CHNChina Yunnan Province Jinuo0.0690109See
TWNTaiwan Bunun8.90.0500101See
USAUSA Spain Ancestry0.0500279See
CHNChina Yunnan Bulang0.0430116See
MYSMalaysia Patani8.00.040025See
TWNTaiwan Puyuma8.00.040050See
CHNChina Yunnan Province Wa0.0380119See
CHNChina Yunnan Province Nu0.0380107See
CHNChina Southwest Dai0.0320124See
CHNChina Han HIV negative0.031072See
CHNChina Henan HIV negative0.031016See
SENSenegal Niokholo Mandenka0.0270165See
USAUSA NMDP Hawaiian or other Pacific Islander0.026111499See
SDNSudan Mixed0.50.0250200See
NZLNew Zealand Polynesians with Full Ancestry4.80.024021See
CHNChina Jingpo Minority4.90.0240105See
NLDNetherlands UMCU4.70.023464See
SRBSerbia pop 23.90.0200102See
TWNTaiwan Tsou3.90.020051See
ASMAmerican Samoa0.020051See
MYSMalaysia Perak Grik Jehai0.020025See
CHNChina Guangxi Region Maonan0.0190108See
TWNTaiwan Atayal3.80.0190106See
NZLNew Zealand Polynesians with Admixed History3.70.019027See
NZLNew Zealand Maori with Admixed History3.80.0190105See
TWNTaiwan Hakka3.60.018055See
MYSMalaysia Champa3.50.017029See
GEOGeorgia Tibilisi Kurd0.017031See
INDIndia Northeast UCBB3.40.0169296See
CHESwitzerland Aargau-Solothurn0.01611838See
SGPSingapore SGVP Chinese CHS0.016096See
POLPoland DKMS0.015520653See
INDIndia New Delhi0.015071See
JPNJapan pop 30.01501018See
MYSMalaysia Peninsular Indian3.00.0148271See
INDIndia Andhra Pradesh Golla0.0140111See
JPNJapan pop 50.0130117See
LKASri Lanka Colombo2.50.0130714See
CHNChina Yunnan Hani0.0130150See
SGPSingapore Chinese2.70.0130149See
VNMVietnam Hanoi Kinh pop 20.0120170See
CHNChina Guizhou Province Miao pop 20.012085See
DEUGermany DKMS - Croatia minority0.01192057See
CHNChina Guizhou Province Shui0.0110153See
NZLNew Zealand Maori with Full Ancestry2.20.011046See
DEUGermany DKMS - Bosnia and Herzegovina minority0.01071028See
RUSRussia Karelia0.01061075See
TUNTunisia Gabes0.010595See
SGPSingapore Javaneses0.010051See
TWNTaiwan Rukai2.00.010050See
TWNTaiwan Paiwan2.00.010051See
PRTPortugal South0.010049See
ZAFSouth Africa Natal Tamil0.010051See
CHNChina Guizhou Province Bouyei0.0100109See
CHESwitzerland Lausanne0.0099993See
HRVCroatia pop 40.00994000See
CZECzech Republic NMDR0.00975099See
DEUGermany DKMS - France minority0.00931406See
USAUSA NMDP Japanese0.009324582See
DEUGermany DKMS - German donors0.00913456066See
CHNChina Canton Han0.0090264See
CHESwitzerland Lugano0.00901169See
CHNChina South Han0.0090284See
CHNChina Tibet Region Tibetan0.0090158See
USAUSA NMDP Caribean Indian0.009014339See
PRTAzores Central Islands0.009059See
TWNTaiwan Tzu Chi Cord Blood Bank0.0090710See
DEUGermany pop 80.008839689See
JPNJapan pop 160.008518604See
DEUGermany pop 60.00818862See
USAUSA North American Native0.0080187See
USAUSA South Texas Hispanic0.0080194See
USAUSA Caucasian pop 20.0080265See
RUSRussia Tuva pop 20.0080169See
ENGEngland North West1.70.0080298See
GNBGuinea Bissau0.008065See
INDIndia East UCBB1.60.00792403See
CHESwitzerland St Gallen0.00792113See
DEUGermany DKMS - Greece minority0.00791894See
USAUSA Asian pop 20.00791772See
MYSMalaysia Peninsular Chinese1.60.0077194See
CHESwitzerland Zurich0.00774875See
CHESwitzerland Bern0.00773545See
HKGHong Kong Chinese BMDR0.00767595See
CHESwitzerland Luzern0.00751553See
DEUGermany DKMS - Austria minority0.00741698See
USAUSA NMDP Caribean Hispanic0.0073115374See
DEUGermany DKMS - Romania minority0.00731234See
INDIndia South UCBB1.40.007011446See
MLIMali Bandiagara0.0070138See
KORSouth Korea pop 30.0070485See
CHNChina Marrow Donor Registry0.0070600See
USAUSA Eastern European0.0070558See
USAUSA Italy Ancestry0.0070273See
ISRIsrael USSR Jews0.007045681See
USAUSA NMDP Vietnamese0.006843540See
DEUGermany DKMS - Portugal minority0.00681176See
TWNTaiwan Tzu Chi Morrow Donor Registry0.006646682See
DEUGermany DKMS - Netherlands minority0.00661374See
CHESwitzerland Sion0.0065832See
USAUSA NMDP European Caucasian0.00641242890See
HKGHong Kong Chinese cord blood registry0.00643892See
USAUSA NMDP Southeast Asian0.006327978See
ISRIsrael Argentina Jews0.00634307See
ISRIsrael Ethiopia Jews0.00625928See
INDIndia Tamil Nadu0.00622492See
USAUSA NMDP Chinese0.006199672See
USAUSA NMDP South Asian Indian0.0061185391See
USAUSA San Antonio Caucasian0.0060222See
TUNTunisia pop 30.0060104See
TWNTaiwan Han Chinese0.0060504See
SGPSingapore Chinese Han0.006094See
SGPSingapore SGVP. Indian INS0.006086See
GRCGreece pop 81.20.006083See
HKGHong Kong Chinese1.20.0060569See
INDIndia Central UCBB1.20.00604204See
INDIndia West UCBB1.10.00575829See
CHESwitzerland Basel0.00561888See
CHNChina Jiangsu Province Han0.0052334See
IRNIran Tabriz Azeris0.005297See
INDIndia North UCBB1.00.00515849See
DEUGermany DKMS - Italy minority0.00521159See
ESPSpain Andalusia Romani0.005099See
ESPSpain (Catalunya, Navarra, Extremadura, Aaragón, Cantabria,1.00.00504335See
CZECzech Republic0.0050106See
CHNChina Hubei Han1.00.00503732See
CHLChile Santiago Mixed1.00.005070See
CHNChina Guangzhou0.0050102See
CHNChina North Han0.0050105See
INDIndia Delhi pop 21.10.005090See
IDNIndonesia Sundanese and Javanese0.0050201See
GEOGeorgia Tibilisi0.0050109See
JPNJapan Central0.0050371See
NLDNetherlands Leiden0.00501305See
USAUSA San Diego1.00.0050496See
USAUSA NMDP Alaska Native or Aleut0.00501376See
USAUSA African American Bethesda1.10.0050187See
USAUSA Hawaii Okinawa0.0050106See
ISRIsrael USA Jews0.00506058See
RUSRussia Bering Island Aleuts0.0048104See
PRTPortugal Azores Terceira Island0.90.0044130See
USAUSA NMDP North American Amerindian0.004435791See
USAUSA NMDP Korean0.004277584See
USAUSA NMDP Mexican or Chicano0.0041261235See
USAUSA NMDP American Indian South or Central America0.00405926See
USAUSA Mexican American Mestizo0.0040553See
USAUSA European American pop 20.00401245See
USAUSA Philadelphia Caucasian0.70.0040141See
USAUSA Asian0.0040358See
PRTAzores Terceira Island0.0040130See
ITAItaly pop 50.0040975See
DEUGermany DKMS - Spain minority0.00411107See
ISRIsrael Poland Jews0.003913871See
USAUSA NMDP Middle Eastern or North Coast of Africa0.003670890See
ISRIsrael Georgia Jews0.00364471See
MEXMexico Mexico City Mestizo population0.0035143See
DEUGermany DKMS - China minority0.00351282See
DEUGermany DKMS - Turkey minority0.00354856See
USAUSA Hispanic pop 20.00351999See
USAUSA NMDP Hispanic South or Central American0.0034146714See
USAUSA NMDP Filipino0.003450614See
ISRIsrael Ashkenazi Jews pop 30.00324625See
USAUSA African American pop 30.0030564See
UGAUganda Kampala0.0030161See
TZATanzania Maasai0.60.0030336See
ISRIsrael Morocco Jews0.002936718See
USAUSA Caucasian pop 40.00281070See
MYSMalaysia Peninsular Malay0.50.0026951See
ISRIsrael Tunisia Jews0.00269070See
DEUGermany DKMS - United Kingdom minority0.00241043See
USAUSA NMDP African American pop 20.0023416581See
KORSouth Korea pop 100.00234128See
USAUSA NMDP Caribean Black0.002233328See
USAUSA African American pop 40.00232411See
MEXMexico Mexico City Mestizo pop 20.0021234See
NIRIreland Northern0.30.00201000See
KENKenya Nandi0.0020240See
CHNChina Beijing Shijiazhuang Tianjian Han0.0020618See
CHNChina Jiangsu Han0.00203238See
CHESwitzerland Graubunden0.0020759See
USAUSA African American pop 80.0020605See
USAUSA San Francisco Caucasian0.0020220See
USAUSA Hispanic0.0020234See
TWNTaiwan pop 20.0020364See
USAUSA NMDP African0.001828557See
NICNicaragua Managua0.30.0015339See
MEXMexico Mexico City Tlalpan0.30.0015330See
COLColombia Bogotá Cord Blood0.20.00101463See
AREUnited Arab Emirates Pop 10.0010570See
ISRIsrael Kavkazi Jews0.00092840See
ISRIsrael Arab pop 20.000912301See
ISRIsrael Druze0.00085914See
CHESwitzerland Geneva pop 20.00031267See
ISRIsrael Iraq Jews0.000213270See
ISRIsrael YemenJews0.000215542See
ISRIsrael Libya Jews0.00003739See
ISRIsrael Bukhara Jews0.00002317See
ISRIsrael Iran Jews0.00008153See
JPNJapan Hokkaido Ainu0.000050See
KENKenya Luo0.0000265See
MARMorocco Settat Chaouya0.00.000098See
MARMorocco Nador Metalsa pop 20.000073See
MEXMexico Mestizo0.00.000041See
INDIndia West Coast Parsi0.000050See
INDIndia West Bhil0.000050See
INDIndia Khandesh Region Pawra0.000050See
INDIndia Mumbai Maratha0.000091See
IDNIndonesia Java pop 20.000036See
BRABrazil Belo Horizonte Caucasian0.00.000095See
AUSAustralia New South Wales Caucasian0.0000134See
CHNChina Beijing0.000067See
CPVCape Verde Northwestern Islands0.000062See
CPVCape Verde Southeastern Islands0.000062See
CUBCuba Mixed Race0.00.000042See
CUBCuba Caucasian0.00.000070See
CHNChina Inner Mongolia Region0.0000102See
CHNChina Qinghai Province Hui0.0000110See
PHLPhilippines Ivatan0.00.000050See
PRTPortugal North0.000046See
PRTPortugal Center0.000050See
PRTAzores Oriental Islands0.000043See
SGPSingapore SGVP Malay MAS0.000089See
TWNTaiwan Pazeh0.00.000055See
TWNTaiwan Siraya0.00.000051See
TWNTaiwan Thao0.00.000030See
TWNTaiwan Minnan pop 10.00.0000102See
TWNTaiwan Taroko0.00.000055See
TWNTaiwan Saisiat0.00.000051See
USAUSA African American0.0000252See
USAUSA Alaska Yupik0.0000252See
TWNTaiwan Tao0.00.000050See
USAUSA Caucasian Bethesda0.00.0000307See
ZAFSouth Africa Natal Zulu0.00.0000100See
ZMBZambia Lusaka0.000044See

Frequency data at lower resolution for this allele can be found in links below

Allele  Number of Populations 


* Allele Frequency: Total number of copies of the allele in the population sample (Alleles / 2n) in decimal format.
   Important: This field has been expanded to four decimals to better represent frequencies of large datasets (e.g. where sample size > 1000 individuals)
* Phenotype Frequency: Percentage of individuals who have the allele or gene (Individuals / n).
* Allele Frequencies shown in green were calculated from Phenotype Frequencies assuming Hardy-Weinberg proportions.

¹ IMGT/HLA Database - For more details of the allele.
² Distribution - Graphical distribution of the allele.
³ Haplotype Association - Find HLA haplotypes with this allele.
ª Notes - See notes for ambiguous combinations of alleles.


Allele frequency net database (AFND) 2020 update: gold-standard data classification, open access genotype data and new query tools
Gonzalez-Galarza FF, McCabe A, Santos EJ, Jones J, Takeshita LY, Ortega-Rivera ND, Del Cid-Pavon GM, Ramsbottom K, Ghattaoraya GS, Alfirevic A, Middleton D and Jones AR Nucleic Acid Research 2020, 48:D783-8.
Liverpool, U.K.

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