Allele Frequencies in World Populations

HLA Database Allele Report

The list below shows all populations in AFND that contains the allele. If an allele has an entry with a lower resolution this will be shown at the end.



Allele reported 54 time(s) and present in 52 population(s).

Population Phenotype
Frequency (%)
Distribution² Haplotype³
INDIndia Andhra Pradesh Telugu Speaking17.70.0887186See
CANCanada Cree NA-DHS_3 (G)16.70.083318See
ZAFSouth African Indian population12.00.060050See
INDIndia Karnataka Kannada Speaking11.50.0570174See
INDIndia Kerala Malayalam speaking11.00.0550356See
ENGEngland Blood Donors of Mixed Ethnicity8.90.0462519See
ZAFSouth Africa Caucasians0.0410102See
ZAFSouth African Mixed ancestry8.00.040050See
USAUSA Italy Ancestry0.0380273See
ENGEngland North West7.00.0370298See
POLPoland BMR7.00.035623595See
CHNChina North Han0.0330105See
ESPSpain, Canary Islands, Gran canaria island6.50.0326215See
CPVCape Verde Northwestern Islands0.032062See
RUSRussia Nizhny Novgorod, Russians6.00.03051510See
USAUSA San Francisco Caucasian0.0280220See
IDNIndonesia Java pop 20.028036See
MARMorocco Atlantic Coast Chaouya0.027098See
MARMorocco Settat Chaouya5.40.027098See
BRABrazil Rio de Janeiro Parda0.0265170See
GTMGuatemala Kaqchikel NA-DHS_8 (G)5.30.026319See
RUSRussia Belgorod region5.20.0261153See
MEXMexico Mixe NA-DHS_6 (G)5.00.025020See
CHLChile Huilliche NA-DHS_14 (G)5.00.025020See
CRICosta Rica Central Valley Mestizo (G)4.60.0230221See
BRABrazil Barra Mansa Rio State Caucasian0.0222405See
RUSRussian Federation Vologda Region4.20.0210119See
RUSRussia Bashkortostan, Tatars4.20.0208192See
USAUSA Mexican American Mestizo0.0200553See
CHNChina Inner Mongolia Region0.0200102See
BRABrazil Rio de Janeiro Caucasian0.0173521See
GRCGreece Athens3.20.01591888See
BRABrazil Rio de Janeiro Black0.014968See
MARMorocco Nador Metalsa pop 20.014073See
RUSRussia Bashkortostan, Bashkirs2.50.0125120See
IDNIndonesia Sundanese and Javanese0.0100201See
LBYLibya Cyrenaica0.0090118See
CHNChina Tibet Region Tibetan0.0090158See
CHNChina Qinghai Province Hui0.0090110See
SAUSaudi Arabia pop 6 (G)0.007128927See
CHNChina Zhejiang Han0.00611734See
CRICosta Rica African -Caribbean (G)1.00.0050102See
CRICosta Rica Guanacaste Mestizo (G)1.00.0050110See
MEXMexico Guadalajara Mestizo pop 20.0050103See
VNMVietnam Kinh1.00.0050101See
SAUSaudi Arabia pop 50.60.0032158See
USAUSA African American pop 30.0030564See
HKGHong Kong Chinese HKBMDR HLA 11 loci0.50.00255266See
USAUSA Spain Ancestry0.0020279See
USAUSA Arizona Gila River Pima0.00023000See
GNBGuinea Bissau0.000065See
CPVCape Verde Southeastern Islands0.000062See

Frequency data at lower resolution for this allele can be found in links below

Allele  Number of Populations 


* Allele Frequency: Total number of copies of the allele in the population sample (Alleles / 2n) in decimal format.
   Important: This field has been expanded to four decimals to better represent frequencies of large datasets (e.g. where sample size > 1000 individuals)
* Phenotype Frequency: Percentage of individuals who have the allele or gene (Individuals / n).
* Allele Frequencies shown in green were calculated from Phenotype Frequencies assuming Hardy-Weinberg proportions.

¹ IMGT/HLA Database - For more details of the allele.
² Distribution - Graphical distribution of the allele.
³ Haplotype Association - Find HLA haplotypes with this allele.
ª Notes - See notes for ambiguous combinations of alleles.

Allele frequency net database (AFND) 2020 update: gold-standard data classification, open access genotype data and new query tools
Gonzalez-Galarza FF, McCabe A, Santos EJ, Jones J, Takeshita LY, Ortega-Rivera ND, Del Cid-Pavon GM, Ramsbottom K, Ghattaoraya GS, Alfirevic A, Middleton D and Jones AR Nucleic Acid Research 2020, 48:D783-8.
Liverpool, U.K.

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