Allele Frequencies in World Populations

HLA Database » Allele Report

The list below shows all populations in AFND that contains the allele. If an allele has an entry with a lower resolution this will be shown at the end.



Allele reported 262 time(s) and present in 127 population(s).

Population Phenotype
Frequency (%)
Distribution² Haplotype³
PAKPakistan Karachi Parsi0.049091See
AREUnited Arab Emirates pop 24.00.0200373See
MEXMexico Baja California, Tijuana0.020025See
MEXMexico San Luis Potosi, San Luis Potosi city0.016730See
MEXMexico Michoacan Tarasco3.00.0150130See
ITAItaly East Sicily2.00.010050See
VENVenezuela Caracas Mestizo0.010050See
MARMorocco Casablanca0.0090100See
BFABurkina Faso Mossi0.009053See
RUSRussia South Ural Bashkir1.40.0070146See
CZECzech Republic Kurd1.40.006874See
ARMArmenia living in Iran0.006085See
VENVenezuela Colonia Tovar0.005886See
RUSRussia Tatars0.0056355See
IRQIraq Erbil1.10.0054372See
SDNSudan Khartoum0.005198See
MEXMexico Sonora, Hermosillo0.005199See
MEXMexico Baja Californa, Mexicali0.0050100See
PAKPakistan Mixed Pathan0.0050100See
TZATanzania Dodoma Kongwa0.0050212See
VENVenezuela Valencia and Maracaibo Caracus Mixed0.005096See
KURIraq Kurdistan Region0.50.0050209See
DZAAlgeria pop 21.00.0050106See
MEXMexico Chihuahua, Ciudad Juarez0.0046106See
MEXMexico Chiapas Rural0.0041121See
TURTurkey pop 50.0040142See
SAUSaudi Arabia pop 20.0040383See
MEXMexico Oaxaca, Oaxaca city0.0033151See
GRCGreece pop 70.003211250See
IRNIran Royan Cord Blood Bank0.50.003015600See
BRABrazil Minas Gerais State Mixed0.60.00301000See
BGDBangladesh Dhaka Bangalee0.0030141See
MEXMexico Veracruz, Veracruz city0.0029171See
ALBAlbania pop 20.50.0023432See
ECUEcuador Coast Mixed Ancestry0.0021238See
ARMArmenia Ghegharkunik0.0020242See
ISRIsrael Jews pop 20.40.002023000See
GRCGreece North0.0020500See
GRCGreece pop30.40.0020246See
ITAItaly Lombardy0.50.0020674See
ITAItaly South Campania Region0.40.00201089See
MKDMacedonia pop 40.0020216See
PRTPortugal Bragança0.0020301See
PRTPortugal Portalegre0.00201254See
SAUSaudi Arabia pop 40.40.0020499See
RUSRussia Moscow0.00202650See
USAUSA OPTN Asian0.0020261See
IRNIran pop 40.0018855See
BRABrazil REDOME Minas Gerais0.0014211275See
BRABrazil REDOME Sao Paulo0.0014800809See
ENGEngland North West Mixed pop 20.30.0013379See
MEXMexico Coahuila, Torreon0.0013396See
BRABrazil REDOME Espirito Santo0.001288485See
BRABrazil REDOME Parana0.0011341639See
CHLChile Santiago0.0011920See
BRABrazil REDOME Mato Grosso0.001034649See
BRABrazil REDOME Rio de Janeiro0.0010139322See
BRABrazil Para State0.10.00105000See
ARMArmenia living in Karabakh0.0010445See
ARMArmenia living in Lebanon0.0010368See
BRABrazil South East Cord Blood0.001011409See
ARGArgentina Cuyo Region0.20.0010420See
FRAFrance Bordeaux0.20.0010990See
FRAFrance Grenoble0.20.00101000See
ITAItaly North Pavia pop 20.20.00102416See
MEXMexico Oaxaca Rural0.0010485See
MEXMexico Puebla, Puebla city0.00101994See
MYSMalaysia pop 30.00101445See
PRTPortugal Lisbon0.001017420See
RUSRussia Samara Region0.00102500See
PRTPortugal Santarem0.00103865See
PRTPortugal Faro0.00101242See
PRTPortugal Guarda0.0010797See
PRTPortugal Leiria0.00101847See
PRTPortugal Vila Real0.00101167See
PRTPortugal South pop 20.00101021See
USAUSA OPTN Hispanic0.00101580See
WALWales pop 20.00.001039979See
RUSRussia Moscow Pop 20.20.00102000See
SVKSlovakia pop 20.00104234See
MEXMexico Veracruz Rural0.0009539See
MEXMexico Jalisco Rural0.0009585See
BRABrazil REDOME Mato Grosso do Sul0.000995667See
BRABrazil REDOME Para0.000972637See
BRABrazil REDOME Goias0.000988574See
BRABrazil REDOME Amapa0.000817864See
BRABrazil REDOME Rondonia0.000854396See
BRABrazil REDOME Santa Catarina0.0008106673See
BRABrazil REDOME Sergipe0.00087321See
ITAItaly North Pavia pop 30.0008685See
BRABrazil REDOME Bahia0.000747399See
BRABrazil REDOME Federal District0.000729549See
MEXMexico Mexico City North0.0007751See
PRTPortugal North pop 20.00071801See
ROMRomania pop 30.10.00071469See
ESPSpain, Castilla y Leon, Northwest,0.30.00071743See
MEXMexico Tlaxcala Rural0.0006830See
MEXMexico Puebla Rural0.0006833See
BRABrazil REDOME Rio Grande do Sul0.0006241329See
BRABrazil REDOME Acre0.0006859See
BRABrazil REDOME Tocantins0.000620692See
BRABrazil Rio Grande do Sul Caucasoid0.00064428See
BRABrazil Para Cord Blood Unit0.00.0006841See
BRABrazil REDOME Pernambuco0.000592332See
BRABrazil REDOME Alagoas0.000525349See
FRAFrance Marseille0.10.00051000See
FRAFrance Rennes pop 40.10.00051000See
POLPoland pop 30.10.00052907See
ECUEcuador Mixed Ancestry0.00041173See
MKDMacedonia MBMDR - Macedonian0.10.00041283See
NORNorway ethnic Norwegians0.10.00034510See
FRAFrance Lyon0.10.00034813See
BRABrazil REDOME Amazonas0.000324129See
BRABrazil REDOME Paraiba0.000343868See
BRABrazil REDOME Rio Grande do Norte0.000346603See
BRABrazil REDOME Piaui0.000246140See
BRABrazil REDOME Roraima0.00024140See
BRABrazil REDOME Ceara0.0002101217See
BRABrazil REDOME Maranhao0.000110180See
IRLIreland South pop 20.000117624See
PRTPortugal North0.000046See
PRTPortugal Viseu0.00002915See
PRTMadeira pop 30.0000538See
PRTPortugal Aveiro0.00005933See
PRTPortugal Beja0.0000699See
PRTPortugal Braga0.00001971See
MYSMalaysia pop 20.000062See
PAKPakistan Mixed Sindhi0.0000101See
RUSRussia Nenet Mixed0.000055See
RUSRussia Arkhangelsk Pomor0.000063See
RUSRussia Murmansk Saomi Mixed0.000070See
PRTPortugal Porto0.00007937See
PRTPortugal Setubal0.00005268See
PRTPortugal Viana do Castelo0.0000706See
PRTPortugal Castelo Branco0.0000327See
PRTPortugal Coimbra0.00005057See
PRTPortugal Evora0.0000737See
PAKPakistan Baloch0.000066See
PAKPakistan Brahui0.0000104See
PAKPakistan Burusho0.000092See
PAKPakistan Kalash0.000069See
MNGMongolia Oold0.0000104See
MNGMongolia Tsaatan0.0000144See
MEXMexico Mexico City East0.000079See
MEXMexico Yucatan, Merida0.0000192See
MEXMexico Campeche, Campeche city0.000034See
MEXMexico Chiapas, Tuxtla Gutierrez0.000052See
MEXMexico Tabasco, Villahermosa0.000082See
MEXMexico Morelos, Cuernavaca0.000082See
MEXMexico Tlaxcala, Tlaxcala city0.0000181See
MEXMexico Mexico City South0.000052See
MEXMexico Coahuila, Saltillo0.000072See
MEXMexico Durango, Durango city0.0000153See
MEXMexico Hidalgo Rural0.000081See
MEXMexico Mexico City Metropolitan Area Rural0.0000150See
MEXMexico Nayarit Rural0.000064See
MEXMexico Baja California Rural0.000050See
MEXMexico Zacatecas, Zacatecas city0.000084See
MEXMexico Sonora, Ciudad Obregón0.0000143See
MEXMexico Baja California, La Paz0.000075See
MEXMexico Veracruz, Poza Rica0.000045See
MEXMexico Veracruz, Cordoba0.000056See
MEXMexico Guerrero state0.0000144See
MEXMexico Tamaulipas, Ciudad Victoria0.000023See
MEXMexico Queretaro, Queretaro city0.000045See
MEXMexico Aguascalientes state0.000095See
MEXMexico Mexico City Center0.0000152See
MEXMexico Hidalgo, Pachuca0.000041See
MEXMexico Veracruz, Xalapa0.0000187See
THAThailand pop 40.000016807See
USAUSA South Texas Hispanic0.0000194See
USAUSA Caucasian Bethesda0.00.0000307See
USAUSA African American Bethesda0.00.0000187See
RUSRussia South Ural Russian0.00.0000207See
RUSRussia South Ural Tatar0.00.0000135See
RUSRussia Northwest pop 30.00.0000100See
ZAFSouth Africa Natal Zulu0.00.0000100See
USAUSA OPTN Caucasian0.00008525See
USAUSA OPTN African American0.00001510See
BRABrazil Rio Grande do Norte Mestizo0.000012973See
BRABrazil Piaui Mixed0.000021943See
CHNChina North Han0.0000105See
CHNChina Shanghai0.000126266See
CHNChina Jiangsu Province0.000020248See
CHNChina Shandong Province0.00.00007418See
CHNChina Shaanxi Province Han0.000010000See
ESPSpain Majorca0.0000407See
ESPSpain Minorca0.000094See
ESPSpain Ibiza0.000088See
ESPSpain Majorcans Jews0.0000103See
ESPSpain Murcia0.0000173See
ECUEcuador Amazonia Mixed Ancestry0.000039See
ECUEcuador Andes Mixed Ancestry0.0000824See
BRABrazil Sao Paulo Bauru Mixed0.00003542See
AUSAustralia West Caucasian0.00.0000891See
BFABurkina Faso Fulani0.000049See
ARGArgentina Corrientes0.00.0000155See
ARGArgentina La Plata0.00.0000100See
ARGArgentina Chiriguano0.00.000054See
ARGArgentina Salta Wichi pop 20.00.000019See
BIHBosnia and Herzegovina0.0000134See
BRABrazil Sao Paulo Mixed0.00.0000239See
BRABrazil Parana Caucasian0.10.00002775See
BRABrazil Parana Cafuzo0.00.0000319See
BRABrazil Parana Mixed race0.00.0000186See
BRABrazil Parana Afro Brazilian0.00.000077See
BRABrazil Parana Oriental0.00.000033See
HRVCroatia pop 20.0000100See
ITAItaly Rome0.00.0000100See
ITAItaly North pop 30.00.000097See
KORSouth Korea pop 10.0000324See
MARMorocco pop 20.0000110See
MEXMexico Mexico City Mestizo0.0000121See
MEXMexico Puebla Mestizo0.000099See
MEXMexico Sinaloa Mestizo0.000056See
MEXMexico Quintana Roo, Cancun0.000048See
MEXMexico Mexico City West0.000033See
MEXMexico Campeche Rural0.000047See
MEXMexico Yucatan Rural0.0000132See
MEXMexico Quintana Roo Rural0.000050See
MEXMexico Morelos Rural0.000030See
MEXMexico Tabasco Rural0.0000142See
MEXMexico Queretaro Rural0.000043See
MEXMexico Tamaulipas Rural0.0000125See
MEXMexico San Luis Potosi Rural0.000087See
MEXMexico Michoacan Rural0.0000348See
MEXMexico Guanajuato Rural0.0000162See
MEXMexico Colima Rural0.000043See
MEXMexico Nuevo Leon Rural0.0000439See
MEXMexico Sonora Rural0.0000197See
MEXMexico Sinaloa Rural0.0000183See
MEXMexico Chihuahua Rural0.0000236See
MEXMexico Durango Rural0.0000326See
MEXMexico Coahuila Rural0.0000216See
MEXMexico Zacatecas Rural0.0000266See
MEXMexico Sinaloa, Culiacán0.0000103See
MEXMexico Chihuahua Chihuahua City0.0000119See
MEXMexico Jalisco, Tonala0.000035See
MEXMexico Jalisco, Tlaquepaque0.000039See
MEXMexico Jalisco, Tlajomulco0.000030See
MEXMexico Jalisco, Guadalajara city0.00001189See
MEXMexico Nayarit, Tepic0.000097See
MEXMexico Zacatecas, Fresnillo0.0000103See
MEXMexico Nuevo Leon, Monterrey city0.0000226See
MEXMexico Colima, Colima city0.000061See
MEXMexico Guanajuato, Leon0.000078See
MEXMexico Guanajuato, Guanajuato city0.000022See
MEXMexico Michoacan, Morelia0.0000150See
MEXMexico Jalisco, Zapopan0.0000168See
MEXMexico Veracruz, Orizaba0.000060See
MEXMexico Veracruz, Coatzacoalcos0.000055See

Frequency data at lower resolution for this allele can be found in links below

Allele  Number of Populations 


* Allele Frequency: Total number of copies of the allele in the population sample (Alleles / 2n) in decimal format.
   Important: This field has been expanded to four decimals to better represent frequencies of large datasets (e.g. where sample size > 1000 individuals)
* Phenotype Frequency: Percentage of individuals who have the allele or gene (Individuals / n).
* Allele Frequencies shown in green were calculated from Phenotype Frequencies assuming Hardy-Weinberg proportions.

¹ IMGT/HLA Database - For more details of the allele.
² Distribution - Graphical distribution of the allele.
³ Haplotype Association - Find HLA haplotypes with this allele.
ª Notes - See notes for ambiguous combinations of alleles.


Allele frequency net database (AFND) 2020 update: gold-standard data classification, open access genotype data and new query tools
Gonzalez-Galarza FF, McCabe A, Santos EJ, Jones J, Takeshita LY, Ortega-Rivera ND, Del Cid-Pavon GM, Ramsbottom K, Ghattaoraya GS, Alfirevic A, Middleton D and Jones AR Nucleic Acid Research 2020, 48:D783-8.
Liverpool, U.K.

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