Allele Frequencies in World Populations

HLA Database » Allele Report

The list below shows all populations in AFND that contains the allele. If an allele has an entry with a lower resolution this will be shown at the end.



Allele reported 244 time(s) and present in 237 population(s).

Population Phenotype
Frequency (%)
Distribution² Haplotype³
COLColombia North Wiwa El Encanto0.509652See
NZLNew Zealand Maori with Full Ancestry71.70.446046See
NCLNew Caledonia0.378065See
AUSAustralia Kimberly Aborigine0.375041See
NZLNew Zealand Maori with Admixed History55.20.3140105See
PNGPapua New Guinea Eastern Highlands Goroka Asaro0.302057See
CHNChina Southwest Dai0.2940124See
CHNChina Guizhou Province Shui0.2840153See
NZLNew Zealand Polynesians with Admixed History51.90.278027See
AUSAustralia Groote Eylandt Aborigine0.267075See
AUSAustralia Yuendumu Aborigine0.2470191See
CHNChina Guizhou Province Miao pop 20.241085See
ASMAmerican Samoa0.240051See
CHNChina Sichuan HIV negative0.221034See
TWNTaiwan Ami39.80.219098See
CHNChina Yunnan Province Han0.2180101See
TWNTaiwan pop 20.2150364See
CHLChile Easter Island0.214021See
NZLNew Zealand Polynesians with Full Ancestry42.90.214021See
TWNTaiwan Han Chinese0.2120504See
VENVenezuela Perja Mountain Bari0.212055See
CHNChina Guizhou Province Bouyei0.2100109See
TWNTaiwan Hakka40.00.209055See
CHNChina Marrow Donor Registry0.2070600See
USAUSA Hawaii Okinawa0.2050106See
CHNChina Hubei Han40.50.20233732See
CHNChina South Han pop 20.20171098See
JPNJapan Aichi36.10.201050See
TWNTaiwan Minnan pop 136.30.2010102See
PNGPapua New Guinea Karimui Plateau Pawaia0.200080See
CHNChina Yunnan Hani0.1930150See
USAUSA NMDP Chinese0.191599672See
HKGHong Kong Chinese BMDR0.18997595See
PNGPapua New Guinea West Schrader Ranges Haruai0.189055See
JPNJapan Kyoto and Osaka0.1850165See
AUSAustralia Cape York Peninsula Aborigine0.1850103See
CHNChina Guangzhou0.1840102See
KORSouth Korea pop 30.1830485See
JPNJapan pop 10.1820560See
JPNJapan pop 30.18201018See
JPNJapan pop 160.176018604See
MYSMalaysia Peninsular Chinese29.40.1753194See
CHNChina Canton Han0.1740264See
USAUSA NMDP Japanese0.173224582See
COLColombia North Chimila Amerindians0.170247See
JPNJapan pop 50.1700117See
CHNChina South Han0.1690284See
SGPSingapore Thai0.1680100See
USAUSA NMDP Korean0.167777584See
USAUSA NMDP Vietnamese0.167343540See
VNMVietnam Hanoi Kinh pop 20.1650170See
DEUGermany DKMS - China minority0.15951282See
CHNChina Shanxi HIV negative0.159022See
CHNChina Henan HIV negative0.156016See
CHNChina Han HIV negative0.156072See
TWNTaiwan Thao30.00.150030See
SGPSingapore SGVP Chinese CHS0.149096See
JPNJapan Central0.1480371See
PNGPapua New Guinea Madang0.147065See
USAUSA Asian0.1380358See
TWNTaiwan Taroko25.50.136055See
MEXMexico Chihuahua Tarahumara0.136044See
USAUSA Asian pop 20.13381772See
PNGPapua New Guinea Wanigela Keapara0.132066See
USAUSA NMDP Hawaiian or other Pacific Islander0.129111499See
TWNTaiwan Pazeh23.60.127055See
CHNChina Qinghai Province Hui0.1270110See
TWNTaiwan Tsou21.60.118051See
TWNTaiwan Bunun18.80.1140101See
COLColombia Bogotá Cord Blood21.10.11381463See
CHNChina North Han0.1100105See
CHNChina Tibet Region Tibetan0.1080158See
PNGPapua New Guinea Wosera Abelam0.1070131See
CHNChina North Han pop 20.1041567See
CHNChina Beijing0.100067See
TWNTaiwan Siraya19.60.098051See
MEXMexico Mexico City Mestizo pop 20.0897234See
CHNChina Inner Mongolia Region0.0880102See
USAUSA North American Native0.0880187See
NICNicaragua Managua16.10.0861339See
INDIndia Tamil Nadu Nadar0.082061See
USAUSA South Dakota Lakota Sioux0.0790302See
RUSRussia Tuva pop 20.0780169See
RUSRussia Transbaikal Territory Buryats15.00.0770150See
PNGPapua New Guinea East New Britain Rabaul0.071060See
TWNTaiwan Rukai14.00.070050See
GEOGeorgia Tibilisi Kurd0.069031See
USAUSA NMDP Southeast Asian0.069027978See
CHNChina Guangdong Province Meizhou Han0.0660100See
MEXMexico Chichen Itza Maya (prehispanic)0.063847See
USAUSA San Diego11.90.0610496See
TWNTaiwan Atayal12.30.0610106See
SGPSingapore Javaneses0.060051See
LKASri Lanka Colombo11.50.0600714See
DEUGermany DKMS - Croatia minority0.05712057See
MEXMexico Mexico City Mestizo population0.0559143See
USAUSA NMDP Hispanic South or Central American0.0544146714See
USAUSA NMDP Alaska Native or Aleut0.05301376See
DEUGermany DKMS - Bosnia and Herzegovina minority0.05161028See
USAUSA Hispanic0.0510234See
SGPSingapore SGVP Malay MAS0.051089See
USAUSA NMDP Mexican or Chicano0.0507261235See
TWNTaiwan Puyuma10.00.050050See
USAUSA Hispanic pop 20.04931999See
USAUSA NMDP North American Amerindian0.049235791See
TWNTaiwan Paiwan9.80.049051See
CHESwitzerland Graubunden0.0478759See
USAUSA NMDP Filipino0.046550614See
MYSMalaysia Peninsular Indian9.20.0461271See
USAUSA NMDP American Indian South or Central America0.04605926See
AUSAustralia New South Wales Caucasian0.0450134See
CHESwitzerland Geneva pop 20.04501267See
MEXMexico Tixcacaltuyub Maya0.044867See
CHESwitzerland Aargau-Solothurn0.04471838See
MYSMalaysia Peninsular Malay8.60.0442951See
POLPoland DKMS0.043220653See
ESPSpain Andalusia0.043099See
CHESwitzerland St Gallen0.04272113See
DEUGermany DKMS - France minority0.04271406See
SGPSingapore Riau Malay0.0420132See
RUSRussia Karelia0.04191075See
INDIndia South UCBB8.20.040811446See
FRAFrance West8.00.0408100See
DEUGermany DKMS - Turkey minority0.04054856See
ENGEngland North West8.10.0400298See
DEUGermany DKMS - Romania minority0.03971234See
CHESwitzerland Sion0.0396832See
CHNChina Yunnan Bulang0.0390116See
CHESwitzerland Lausanne0.0390993See
MKDMacedonia pop 40.0390216See
ESPSpain (Catalunya, Navarra, Extremadura, Aaragón, Cantabria,7.40.03784335See
SGPSingapore SGVP. Indian INS0.037086See
USAUSA Eastern European0.0370558See
USAUSA New Mexico Canoncito Navajo0.037042See
CHESwitzerland Lugano0.03671169See
CHESwitzerland Bern0.03663545See
DEUGermany DKMS - Greece minority0.03631894See
INDIndia New Delhi0.036071See
CHESwitzerland Zurich0.03604875See
INDIndia Tamil Nadu0.03572492See
DEUGermany pop 80.035739689See
INDIndia East UCBB7.10.03542403See
DEUGermany pop 60.03528862See
USAUSA NMDP South Asian Indian0.0351185391See
DEUGermany DKMS - German donors0.03513456066See
GRCGreece pop 60.0351242See
PRTPortugal Center pop 20.0350562See
DEUGermany DKMS - Austria minority0.03481698See
CHESwitzerland Luzern0.03421553See
USAUSA NMDP European Caucasian0.03411242890See
USAUSA San Antonio Caucasian0.0333222See
CZECzech Republic NMDR0.03315099See
GEOGeorgia Tibilisi0.0330109See
ITAItaly pop 50.0330975See
BRABrazil Terena6.00.032060See
DEUGermany DKMS - United Kingdom minority0.03191043See
NLDNetherlands UMCU6.30.031264See
IRNIran Baloch0.0310100See
INDIndia Delhi pop 26.20.031090See
SENSenegal Niokholo Mandenka0.0310165See
DEUGermany DKMS - Italy minority0.03051159See
INDIndia West UCBB6.10.03055829See
INDIndia Northeast UCBB6.10.0304296See
DEUGermany DKMS - Netherlands minority0.03021374See
GRCGreece pop 86.00.030183See
INDIndia West Coast Parsi0.030050See
MEXMexico Oaxaca Mixtec0.0300103See
MEXMexico Oaxaca Zapotec0.030090See
USAUSA South Texas Hispanic0.0300194See
INDIndia North UCBB5.80.02915849See
INDIndia Central UCBB5.60.02824204See
IRLIreland South5.20.0280250See
GBRUnited Kingdom pop 35.50.0280604See
USAUSA Caucasian pop 20.0280265See
FRAFrance Southeast5.40.0270130See
DEUGermany DKMS - Spain minority0.02681107See
USAUSA NMDP Middle Eastern or North Coast of Africa0.026070890See
USAUSA Caucasian Bethesda5.30.0260307See
USAUSA Philadelphia Caucasian4.10.0260141See
CHNChina Uyghur HIV negative0.026019See
CHLChile Santiago Mixed5.00.025370See
ESPSpain Sevilla5.00.0252278See
USAUSA Caucasian pop 40.02521070See
USAUSA NMDP Caribean Indian0.025014339See
UGAUganda Kampala0.0250161See
NLDNetherlands Leiden0.02501305See
NIRIreland Northern4.80.02401000See
BRABrazil Mixed0.0240108See
VENVenezuela Sierra de Perija Yucpa0.024073See
USAUSA NMDP Caribean Hispanic0.0237115374See
IRNIran Gorgan0.023464See
AREUnited Arab Emirates Pop 10.0230570See
ENGEngland London Ashkenazi Jews0.0230500See
USAUSA San Francisco Caucasian0.0230220See
ZAFSouth Africa Natal Tamil0.021051See
ITAItaly South0.0210141See
DEUGermany DKMS - Portugal minority0.02091176See
ITAItaly North0.0200277See
ZAFSouth Africa Caucasians0.0200102See
TWNTaiwan Saisiat3.90.020051See
CHESwitzerland Basel0.01911888See
CZECzech Republic0.0190106See
INDIndia Mumbai Maratha0.019091See
BRABrazil Puyanawa3.30.0170150See
MEXMexico Chiapas Lacandon Mayans0.0161218See
ISRIsrael Ashkenazi and Non Ashkenazi Jews0.0160146See
USAUSA African American Bethesda3.20.0160187See
CHESwitzerland Geneva0.013080See
SAUSaudi Arabia Guraiat and Hail2.40.0120213See
PRTAzores Terceira Island0.0120130See
USAUSA Alaska Yupik0.0110252See
PHLPhilippines Ivatan2.00.010050See
ISRIsrael Arab Druze0.0100101See
RUSRussia Bering Island Aleuts0.0096104See
ZAFSouth Africa Worcester2.00.0090159See
USAUSA NMDP Caribean Black0.008633328See
USAUSA African American pop 40.00852411See
MLIMali Bandiagara0.0080138See
RUSRussia North Ossetian1.60.0079127See
USAUSA NMDP African American pop 20.0078416581See
JORJordan Amman0.0070146See
MARMorocco Settat Chaouya1.40.007098See
MARMorocco Atlantic Coast Chaouya0.007098See
USAUSA Arizona Gila River Amerindian0.0060492See
LBNLebanon Mixed0.005097See
USAUSA NMDP African0.004828557See
PRTPortugal Azores Terceira Island0.90.0044130See
KENKenya Nandi0.0020240See
SDNSudan Mixed3.00.0020200See
TZATanzania Maasai0.30.0016336See
TWNTaiwan Tao0.00.000050See
USAUSA African American0.0000252See
ZMBZambia Lusaka0.000044See
KENKenya Luo0.0000265See
MARMorocco Nador Metalsa pop 20.000073See
INDIndia West Bhil0.000050See
INDIndia Khandesh Region Pawra0.000050See
BRABrazil Vale do Ribeira Quilombos0.00.0000144See

Frequency data at lower resolution for this allele can be found in links below

Allele  Number of Populations 


* Allele Frequency: Total number of copies of the allele in the population sample (Alleles / 2n) in decimal format.
   Important: This field has been expanded to four decimals to better represent frequencies of large datasets (e.g. where sample size > 1000 individuals)
* Phenotype Frequency: Percentage of individuals who have the allele or gene (Individuals / n).
* Allele Frequencies shown in green were calculated from Phenotype Frequencies assuming Hardy-Weinberg proportions.

¹ IMGT/HLA Database - For more details of the allele.
² Distribution - Graphical distribution of the allele.
³ Haplotype Association - Find HLA haplotypes with this allele.
ª Notes - See notes for ambiguous combinations of alleles.


Allele frequency net database (AFND) 2020 update: gold-standard data classification, open access genotype data and new query tools
Gonzalez-Galarza FF, McCabe A, Santos EJ, Jones J, Takeshita LY, Ortega-Rivera ND, Del Cid-Pavon GM, Ramsbottom K, Ghattaoraya GS, Alfirevic A, Middleton D and Jones AR Nucleic Acid Research 2020, 48:D783-8.
Liverpool, U.K.

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