Allele Frequencies in World Populations

HLA Database » Allele Report

The list below shows all populations in AFND that contains the allele. If an allele has an entry with a lower resolution this will be shown at the end.



Allele reported 226 time(s) and present in 220 population(s).

Population Phenotype
Frequency (%)
Distribution² Haplotype³
MEXMexico Chihuahua Tarahumara0.398044See
BRABrazil Terena54.00.351060See
RUSRussia Sakhalin Island Nivkhi0.321053See
MEXMexico Chiapas Lacandon Mayans0.2798218See
MEXMexico Chichen Itza Maya (prehispanic)0.276647See
CHNChina Guizhou Province Miao pop 20.235085See
CHNChina Guizhou Province Bouyei0.2230109See
PNGPapua New Guinea Wosera Abelam0.2230131See
MEXMexico Oaxaca Mixe0.217055See
USAUSA NMDP Alaska Native or Aleut0.20601376See
USAUSA Arizona Gila River Amerindian0.1950492See
RUSRussia Transbaikal Territory Buryats33.00.1870150See
PNGPapua New Guinea Karimui Plateau Pawaia0.181080See
MEXMexico Tixcacaltuyub Maya0.171667See
CHNChina Southwest Dai0.1650124See
RUSRussia Bering Island Aleuts0.1635104See
CHNChina Shanxi HIV negative0.159022See
CHNChina Wuhan27.50.1490121See
CHNChina Guizhou Province Shui0.1470153See
RUSRussia Nenet Mixed0.143055See
NLDNetherlands UMCU28.10.140664See
JPNJapan Central0.1370371See
CHNChina North Han0.1330105See
JPNJapan pop 30.13001018See
JPNJapan Kyoto and Osaka0.1300165See
CHNChina South Han0.1280284See
JPNJapan pop 10.1270560See
USAUSA NMDP Japanese0.126924582See
JPNJapan pop 160.123918604See
TWNTaiwan Han Chinese0.1220504See
SGPSingapore SGVP Chinese CHS0.122096See
HKGHong Kong Chinese BMDR0.12187595See
CHNChina South Han pop 20.12071098See
NZLNew Zealand Polynesians with Full Ancestry19.00.119021See
MYSMalaysia Peninsular Chinese22.70.1186194See
CHNChina Sichuan HIV negative0.118034See
CHNChina Hubei Han23.50.11753732See
USAUSA NMDP Hawaiian or other Pacific Islander0.117311499See
USAUSA South Texas Hispanic0.1170194See
CHNChina Guangzhou0.1170102See
COLColombia North Chimila Amerindians0.117047See
USAUSA NMDP Chinese0.116599672See
KORSouth Korea pop 10.1160324See
CHNChina Beijing0.114067See
DEUGermany DKMS - Netherlands minority0.11391374See
JPNJapan pop 50.1130117See
TWNTaiwan pop 20.1130364See
USAUSA North American Native0.1120187See
CHNChina Marrow Donor Registry0.1120600See
CHNChina Canton Han0.1120264See
NZLNew Zealand Polynesians with Admixed History18.50.111027See
NLDNetherlands Leiden0.10901305See
JPNJapan Hyogo18.80.109032See
THAThailand Northeast pop 20.1060400See
CHNChina Uyghur HIV negative0.105019See
DEUGermany Essen20.70.1050174See
MEXMexico Oaxaca Zapotec0.104090See
USAUSA NMDP North American Amerindian0.101635791See
USAUSA NMDP Korean0.101377584See
THAThailand Northeast0.100066See
RUSRussia Arkhangelsk Pomor0.100063See
USAUSA Caucasian pop 40.10001070See
USAUSA Asian0.1000358See
CHNChina Yunnan Province Han0.0990101See
PNGPapua New Guinea Madang0.095065See
CHNChina Tibet Region Tibetan0.0920158See
CHNChina North Han pop 20.0882567See
COLColombia North Wiwa El Encanto0.086552See
USAUSA Asian pop 20.08351772See
PNGPapua New Guinea Wanigela Keapara0.083066See
GBRUnited Kingdom pop 316.20.0830604See
DEUGermany DKMS - United Kingdom minority0.08291043See
USAUSA Caucasian pop 20.0820265See
USAUSA NMDP American Indian South or Central America0.08205926See
DEUGermany DKMS - China minority0.08171282See
COLColombia Bogotá Cord Blood15.70.08171463See
DEUGermany DKMS - German donors0.08163456066See
RUSRussia Karelia0.08151075See
DEUGermany pop 60.08048862See
BRABrazil Puyanawa15.30.0800150See
USAUSA San Antonio Caucasian0.0788222See
ENGEngland North West14.40.0760298See
USAUSA NMDP European Caucasian0.07491242890See
DEUGermany pop 80.074139689See
AUSAustralia New South Wales Caucasian0.0740134See
SENSenegal Niokholo Mandenka0.0740165See
NICNicaragua Managua13.60.0733339See
CHESwitzerland Aargau-Solothurn0.07301838See
USAUSA Hispanic0.0730234See
DEUGermany DKMS - Austria minority0.07291698See
USAUSA NMDP Mexican or Chicano0.0726261235See
USAUSA Caucasian Bethesda13.60.0720307See
USAUSA NMDP Vietnamese0.072043540See
PERPeru Arequipa Mestizo13.50.0710168See
CHESwitzerland St Gallen0.07082113See
GNQEquatorial Guinea Bioko Island Bubi0.0700100See
MEXMexico Mexico City Mestizo population0.0699143See
USAUSA Hispanic pop 20.06981999See
ESPSpain Catalonia Girona0.069088See
CHESwitzerland Zurich0.06814875See
ZMBZambia Lusaka0.067044See
MEXMexico Mexico City Mestizo pop 20.0662234See
USAUSA Philadelphia Caucasian13.30.0660141See
GHAGhana Ga-Adangbe13.00.0649131See
USAUSA NMDP Filipino0.064650614See
DEUGermany DKMS - France minority0.06461406See
NIRIreland Northern12.10.06401000See
USAUSA African American Bethesda12.80.0640187See
ZWEZimbabwe Harare Shona0.0640230See
CHESwitzerland Basel0.06311888See
UGAUganda Kampala pop 20.0630175See
VNMVietnam Hanoi Kinh pop 20.0620170See
USAUSA San Diego11.50.0610496See
USAUSA Eastern European0.0610558See
BFABurkina Faso Fulani0.061049See
CZECzech Republic NMDR0.06025099See
USAUSA NMDP Hispanic South or Central American0.0602146714See
RUSRussia Murmansk Saomi Mixed0.060070See
CHNChina Qinghai Province Hui0.0590110See
USAUSA NMDP African American pop 20.0565416581See
SGPSingapore SGVP. Indian INS0.056086See
NCLNew Caledonia0.056065See
ZAFSouth Africa Caucasians0.0540102See
CHESwitzerland Bern0.05393545See
POLPoland DKMS0.053820653See
USAUSA African American pop 40.05332411See
CZECzech Republic0.0520106See
SCOScotland Orkney9.60.051099See
ZAFSouth Africa Worcester10.00.0500159See
CHNChina Yunnan Hani0.0500150See
KENKenya, Nyanza Province, Luo tribe10.00.0500100See
ESPSpain Gipuzkoa Basque0.0500100See
IRLIreland South10.00.0500250See
CHESwitzerland Geneva pop 20.04981267See
USAUSA NMDP Caribean Black0.049733328See
UGAUganda Kampala0.0490161See
USAUSA NMDP African0.048628557See
CHESwitzerland Luzern0.04721553See
KENKenya Luo0.0470265See
FRAFrance West9.00.0460100See
CHLChile Santiago Mixed9.00.046070See
USAUSA NMDP Caribean Hispanic0.0452115374See
USAUSA NMDP Caribean Indian0.045014339See
USAUSA African American0.0440252See
USAUSA San Francisco Caucasian0.0440220See
USAUSA NMDP Southeast Asian0.044027978See
CHNChina Yunnan Bulang0.0430116See
MYSMalaysia Peninsular Malay8.10.0426951See
KENKenya Nandi0.0420240See
CHESwitzerland Lausanne0.0417993See
DEUGermany DKMS - Romania minority0.04131234See
MEXMexico Oaxaca Mixtec0.0400103See
KORSouth Korea pop 30.0390485See
SGPSingapore SGVP Malay MAS0.039089See
CMRCameroon Sawa0.038013See
BFABurkina Faso Mossi0.038053See
DEUGermany DKMS - Portugal minority0.03601176See
DEUGermany DKMS - Spain minority0.03341107See
DEUGermany DKMS - Greece minority0.03301894See
ESPSpain Majorca and Minorca0.033090See
PNGPapua New Guinea West Schrader Ranges Haruai0.033055See
CMRCameroon Beti0.0320174See
DEUGermany DKMS - Croatia minority0.03152057See
CHESwitzerland Sion0.0314832See
TZATanzania Maasai5.30.0312336See
FRAFrance Southeast6.20.0310130See
ESPSpain (Catalunya, Navarra, Extremadura, Aaragón, Cantabria,5.90.03004335See
CHESwitzerland Lugano0.02971169See
INDIndia Northeast UCBB5.70.0287296See
USAUSA NMDP Middle Eastern or North Coast of Africa0.028470890See
DEUGermany DKMS - Turkey minority0.02684856See
DEUGermany DKMS - Bosnia and Herzegovina minority0.02481028See
ESPSpain Andalusia0.024099See
GEOGeorgia Tibilisi0.0230109See
AUSAustralia Cape York Peninsula Aborigine0.0220103See
PRTPortugal Center pop 20.0220562See
ESPSpain Sevilla4.30.0216278See
BFABurkina Faso Rimaibe0.021047See
AREUnited Arab Emirates Pop 10.0210570See
DEUGermany DKMS - Italy minority0.02071159See
ENGEngland London Ashkenazi Jews0.0200500See
INDIndia Tamil Nadu0.02002492See
INDIndia Delhi pop 23.70.019090See
ESPSpain Andalusia Romani0.019099See
CHESwitzerland Geneva0.019080See
INDIndia South UCBB3.80.018911446See
PNGPapua New Guinea East New Britain Rabaul0.018060See
SDNSudan Mixed3.50.0180200See
PRTPortugal Azores Terceira Island3.50.0175130See
INDIndia West UCBB3.30.01645829See
INDIndia North UCBB3.30.01625849See
USAUSA NMDP South Asian Indian0.0162185391See
PRTAzores Terceira Island0.0160130See
ITAItaly Bergamo3.00.0160101See
MLIMali Bandiagara0.0160138See
INDIndia Central UCBB3.20.01584204See
LKASri Lanka Colombo3.10.0150714See
ITAItaly pop 50.0150975See
INDIndia East UCBB3.00.01482403See
NZLNew Zealand Maori with Admixed History2.90.0140105See
CMRCameroon Bamileke0.013077See
MYSMalaysia Peninsular Indian2.60.0129271See
GRCGreece pop 60.0124242See
ITAItaly North Pavia0.012081See
RUSRussia North Ossetian2.40.0118127See
NZLNew Zealand Maori with Full Ancestry2.20.011046See
ITAItaly North0.0110277See
CHESwitzerland Graubunden0.0077759See
AUSAustralia Groote Eylandt Aborigine0.007075See
TURTurkey pop 50.0070142See
SAUSaudi Arabia Guraiat and Hail1.00.0050213See
AUSAustralia Yuendumu Aborigine0.0050191See
RUSRussia Belgorod region0.70.0033153See
PNGPapua New Guinea Eastern Highlands Goroka Asaro0.000057See
BRABrazil Vale do Ribeira Quilombos0.10.0000144See
CMRCameroon Baka Pygmy0.000010See
ITAItaly South0.0000141See
MARMorocco Nador Metalsa pop 20.000073See
ITAItaly Sardinia pop30.0000100See
FRAFrance Corsica Island0.0000100See

Frequency data at lower resolution for this allele can be found in links below

Allele  Number of Populations 


* Allele Frequency: Total number of copies of the allele in the population sample (Alleles / 2n) in decimal format.
   Important: This field has been expanded to four decimals to better represent frequencies of large datasets (e.g. where sample size > 1000 individuals)
* Phenotype Frequency: Percentage of individuals who have the allele or gene (Individuals / n).
* Allele Frequencies shown in green were calculated from Phenotype Frequencies assuming Hardy-Weinberg proportions.

¹ IMGT/HLA Database - For more details of the allele.
² Distribution - Graphical distribution of the allele.
³ Haplotype Association - Find HLA haplotypes with this allele.
ª Notes - See notes for ambiguous combinations of alleles.


Allele frequency net database (AFND) 2020 update: gold-standard data classification, open access genotype data and new query tools
Gonzalez-Galarza FF, McCabe A, Santos EJ, Jones J, Takeshita LY, Ortega-Rivera ND, Del Cid-Pavon GM, Ramsbottom K, Ghattaoraya GS, Alfirevic A, Middleton D and Jones AR Nucleic Acid Research 2020, 48:D783-8.
Liverpool, U.K.

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