Allele Frequencies in World Populations

HLA Database » Allele Report

The list below shows all populations in AFND that contains the allele. If an allele has an entry with a lower resolution this will be shown at the end.



Allele reported 164 time(s) and present in 125 population(s).

Population Phenotype
Frequency (%)
Distribution² Haplotype³
PNGPapua New Guinea West Schrader Ranges Haruai0.459055See
TWNTaiwan Tao66.00.400050See
PNGPapua New Guinea Eastern Highlands Goroka Asaro0.349057See
CHLChile Easter Island0.262021See
PNGPapua New Guinea Madang0.250065See
NZLNew Zealand Polynesians with Full Ancestry33.30.167021See
PNGPapua New Guinea Wanigela Keapara0.160066See
AUSAustralia Cape York Peninsula Aborigine0.1570103See
AUSAustralia Yuendumu Aborigine0.1510191See
NZLNew Zealand Polynesians with Admixed History29.60.148027See
SGPSingapore SGVP Malay MAS0.129089See
AUSAustralia Groote Eylandt Aborigine0.123075See
TWNTaiwan Puyuma24.00.120050See
PNGPapua New Guinea Karimui Plateau Pawaia0.119080See
TWNTaiwan Pazeh21.80.118055See
TWNTaiwan Thao23.30.117030See
NCLNew Caledonia0.111065See
SGPSingapore Riau Malay0.0980132See
CHNChina Yunnan Bulang0.0910116See
PNGPapua New Guinea East New Britain Rabaul0.089060See
NZLNew Zealand Maori with Full Ancestry17.40.087046See
PNGPapua New Guinea Wosera Abelam0.0800131See
USAUSA NMDP Hawaiian or other Pacific Islander0.071111499See
NZLNew Zealand Maori with Admixed History13.30.0710105See
SGPSingapore Javaneses0.070051See
TWNTaiwan Rukai12.00.070050See
MYSMalaysia Peninsular Malay13.00.0689951See
TWNTaiwan Bunun12.90.0640101See
ASMAmerican Samoa0.060051See
VNMVietnam Hanoi Kinh pop 20.0590170See
SGPSingapore Thai0.0540100See
USAUSA NMDP Filipino0.053150614See
PHLPhilippines Ivatan10.00.050050See
TWNTaiwan Siraya9.80.049051See
TWNTaiwan Tsou9.80.049051See
USAUSA NMDP Vietnamese0.045043540See
CHNChina Sichuan HIV negative0.044034See
CHNChina Southwest Dai0.0400124See
INDIndia Northeast UCBB7.80.0389296See
CHNChina Guizhou Province Shui0.0360153See
AUSAustralia Kimberly Aborigine0.036041See
CHNChina Yunnan Province Han0.0350101See
TWNTaiwan Atayal6.60.0330106See
ZAFSouth Africa Natal Tamil0.031051See
MYSMalaysia Peninsular Indian5.20.0277271See
CHNChina Guizhou Province Bouyei0.0270109See
CHNChina Yunnan Hani0.0270150See
TWNTaiwan Ami5.10.026098See
MYSMalaysia Peninsular Chinese5.20.0258194See
LKASri Lanka Colombo4.20.0210714See
CHNChina South Han0.0210284See
HKGHong Kong Chinese BMDR0.02057595See
INDIndia Tamil Nadu0.02012492See
USAUSA Asian0.0200358See
INDIndia South UCBB4.00.019811446See
CHNChina Canton Han0.0190264See
TWNTaiwan Han Chinese0.0190504See
USAUSA NMDP Southeast Asian0.018927978See
INDIndia East UCBB3.60.01812403See
TWNTaiwan Hakka3.60.018055See
CHNChina Marrow Donor Registry0.0150600See
USAUSA Asian pop 20.01471772See
CHNChina Qinghai Province Hui0.0140110See
CHNChina Jingpo Minority2.90.0140105See
USAUSA NMDP South Asian Indian0.0138185391See
CHNChina South Han pop 20.01321098See
IRNIran Tehran0.0130120See
INDIndia Central UCBB2.60.01284204See
INDIndia West UCBB2.50.01245829See
SGPSingapore SGVP. Indian INS0.012086See
USAUSA NMDP Chinese0.011299672See
INDIndia North UCBB2.10.01075849See
INDIndia West Coast Parsi0.010050See
CHNChina Guangdong Province Meizhou Han0.0100100See
CHNChina Inner Mongolia Region0.0100102See
TWNTaiwan Paiwan2.00.010051See
TWNTaiwan Minnan pop 12.00.0100102See
DEUGermany DKMS - China minority0.00921282See
INDIndia New Delhi0.009071See
RUSRussia Tuva pop 20.0090169See
CHNChina Hubei Han1.70.00863732See
TWNTaiwan pop 20.0080364See
CHNChina Tibet Region Tibetan0.0060158See
AUSAustralia New South Wales Caucasian0.0050134See
ISRIsrael Ashkenazi and Non Ashkenazi Jews0.0050146See
SGPSingapore SGVP Chinese CHS0.005096See
AREUnited Arab Emirates Pop 10.0040570See
CHESwitzerland Luzern0.00401553See
SAUSaudi Arabia pop 50.60.0032158See
USAUSA San Diego0.60.0030496See
USAUSA Eastern European0.0030558See
ZAFSouth Africa Worcester1.00.0030159See
SAUSaudi Arabia pop 6 (G)0.002528927See
CHESwitzerland Basel0.00191888See
CHNChina North Han pop 20.0018567See
TZATanzania Maasai0.30.0016336See
USAUSA NMDP American Indian South or Central America0.00105926See
USAUSA NMDP Caribean Indian0.001014339See
NLDNetherlands Leiden0.00101305See
USAUSA African American pop 30.0010564See
DEUGermany DKMS - Turkey minority0.00064856See
USAUSA NMDP Middle Eastern or North Coast of Africa0.000470890See
USAUSA NMDP Caribean Hispanic0.0004115374See
USAUSA NMDP Caribean Black0.000433328See
CZECzech Republic NMDR0.00045099See
DEUGermany DKMS - Portugal minority0.00041176See
DEUGermany DKMS - Spain minority0.00051107See
DEUGermany DKMS - United Kingdom minority0.00051043See
USAUSA African American pop 40.00042411See
USAUSA NMDP Japanese0.000324582See
DEUGermany DKMS - Austria minority0.00031698See
DEUGermany pop 80.000339689See
USAUSA NMDP Korean0.000377584See
USAUSA NMDP Hispanic South or Central American0.0003146714See
DEUGermany DKMS - German donors0.00033456066See
USAUSA NMDP North American Amerindian0.000335791See
DEUGermany DKMS - Greece minority0.00031894See
USAUSA Hispanic pop 20.00031999See
USAUSA NMDP African0.000128557See
USAUSA NMDP African American pop 20.0001416581See
ESPSpain (Catalunya, Navarra, Extremadura, Aaragón, Cantabria,0.00.00014335See
DEUGermany pop 60.00018862See
USAUSA NMDP Mexican or Chicano0.0001261235See
USAUSA NMDP European Caucasian0.00011242890See
USAUSA San Antonio Caucasian0.0000222See
USAUSA South Texas Hispanic0.0000194See
USAUSA Alaska Yupik0.0000252See
USAUSA Caucasian pop 20.0000265See
USAUSA African American0.0000252See
USAUSA Hispanic0.0000234See
POLPoland DKMS0.000120653See
TWNTaiwan Taroko0.00.000055See
TWNTaiwan Saisiat0.00.000051See
SENSenegal Niokholo Mandenka0.0000165See
NIRIreland Northern0.00.00001000See
FRAFrance West0.00.0000100See
GBRUnited Kingdom pop 30.00.0000604See
CZECzech Republic0.0000106See
ITAItaly North pop 30.00.000097See
ITAItaly Bergamo0.00.0000101See
ITAItaly pop 50.0000975See
KORSouth Korea pop 30.0000485See
MARMorocco Settat Chaouya0.00.000098See
MARMorocco Nador Metalsa pop 20.000073See
INDIndia West Bhil0.000050See
INDIndia Khandesh Region Pawra0.000050See
INDIndia Mumbai Maratha0.000091See
CHNChina Guizhou Province Miao pop 20.000085See
CHNChina North Han0.0000105See
CHESwitzerland Geneva pop 20.00001267See
CHESwitzerland Graubunden0.0000759See
CHESwitzerland Lugano0.00001169See
CHESwitzerland Lausanne0.0000993See
CHESwitzerland St Gallen0.00002113See
CHESwitzerland Sion0.0000832See
CHESwitzerland Zurich0.00004875See
CHESwitzerland Geneva0.000080See
CHESwitzerland Aargau-Solothurn0.00001838See
CHESwitzerland Bern0.00003545See
USAUSA Caucasian Bethesda0.00.0000307See
USAUSA African American Bethesda0.00.0000187See
USAUSA Philadelphia Caucasian0.00.0000141See
USAUSA North American Native0.0000187See

Frequency data at lower resolution for this allele can be found in links below

Allele  Number of Populations 


* Allele Frequency: Total number of copies of the allele in the population sample (Alleles / 2n) in decimal format.
   Important: This field has been expanded to four decimals to better represent frequencies of large datasets (e.g. where sample size > 1000 individuals)
* Phenotype Frequency: Percentage of individuals who have the allele or gene (Individuals / n).
* Allele Frequencies shown in green were calculated from Phenotype Frequencies assuming Hardy-Weinberg proportions.

¹ IMGT/HLA Database - For more details of the allele.
² Distribution - Graphical distribution of the allele.
³ Haplotype Association - Find HLA haplotypes with this allele.
ª Notes - See notes for ambiguous combinations of alleles.


Allele frequency net database (AFND) 2020 update: gold-standard data classification, open access genotype data and new query tools
Gonzalez-Galarza FF, McCabe A, Santos EJ, Jones J, Takeshita LY, Ortega-Rivera ND, Del Cid-Pavon GM, Ramsbottom K, Ghattaoraya GS, Alfirevic A, Middleton D and Jones AR Nucleic Acid Research 2020, 48:D783-8.
Liverpool, U.K.

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