Allele Frequencies in World Populations

HLA Database Allele Report

The list below shows all populations in AFND that contains the allele. If an allele has an entry with a lower resolution this will be shown at the end.



Allele reported 45 time(s) and present in 45 population(s).

Population Phenotype
Frequency (%)
Distribution² Haplotype³
CANCanada Chipewyan NA-DHS_2 (G)24.00.120025See
ENGEngland Blood Donors of Mixed Ethnicity21.10.1060519See
GTMGuatemala Kaqchikel NA-DHS_8 (G)21.10.105319See
ESPSpain, Canary Islands, Gran canaria island19.10.0977215See
USAUSA Italy Ancestry0.0810273See
USAUSA San Francisco Caucasian0.0760220See
CRICosta Rica Guanacaste Mestizo (G)13.60.0680110See
CANCanada Ojibwa NA-DHS_4 (G)13.30.066716See
BRABrazil Rio de Janeiro Caucasian0.0630521See
BRABrazil Rio de Janeiro Black0.062568See
CRICosta Rica Central Valley Mestizo (G)12.20.0610221See
BRABrazil Barra Mansa Rio State Caucasian0.0556405See
ZAFSouth Africa Caucasians0.0540102See
USAUSA Mexican American Mestizo0.0520553See
BRABrazil Rio de Janeiro Parda0.0509170See
COLColombia Waunana NA-DHS_20 (G)5.00.050020See
MARMorocco Settat Chaouya8.60.043098See
MARMorocco Atlantic Coast Chaouya0.043098See
POLPoland BMR8.00.040823595See
RUSRussia Belgorod region7.80.0392153See
NICNicaragua Mestizo (G)7.20.0360155See
COLColombia Wayuu NA-DHS_15 (G)7.10.035715See
RUSRussia Tundra Nentsi NA-DHS_1 (G)6.70.033316See
USAUSA African American pop 30.0330564See
CHLChile Huilliche NA-DHS_14 (G)6.30.031220See
CANCanada Cree NA-DHS_3 (G)5.60.027818See
RUSRussian Federation Vologda Region5.00.0252119See
CHNChina Yunnan Province Nu0.0240107See
MEXMexico Hidalgo Mezquital Valley/ Otomi4.20.020872See
ZAFSouth African Mixed ancestry4.00.020050See
USAUSA Spain Ancestry0.0160279See
BRABrazil Barra Mansa Rio State Black0.014373See
SAUSaudi Arabia pop 6 (G)0.013228927See
ZAFSouth African Black2.10.0106142See
CRICosta Rica African -Caribbean (G)2.00.0100102See
RUSRussia Bashkortostan, Tatars1.60.0078192See
INDIndia Kerala Malayalam speaking1.40.0070356See
CHNChina Yunnan Province Lisu0.0070111See
RUSRussia Nizhny Novgorod, Russians1.10.00601510See
INDIndia Andhra Pradesh Telugu Speaking1.10.0054186See
CRICosta Rica Amerindians (G)0.80.0040125See
INDIndia Karnataka Kannada Speaking0.60.0030174See
CHNChina Zhejiang Han0.00291734See
HKGHong Kong Chinese HKBMDR HLA 11 loci0.30.00155266See
USAUSA Arizona Gila River Pima0.00063000See

Frequency data at lower resolution for this allele can be found in links below

Allele  Number of Populations 


* Allele Frequency: Total number of copies of the allele in the population sample (Alleles / 2n) in decimal format.
   Important: This field has been expanded to four decimals to better represent frequencies of large datasets (e.g. where sample size > 1000 individuals)
* Phenotype Frequency: Percentage of individuals who have the allele or gene (Individuals / n).
* Allele Frequencies shown in green were calculated from Phenotype Frequencies assuming Hardy-Weinberg proportions.

¹ IMGT/HLA Database - For more details of the allele.
² Distribution - Graphical distribution of the allele.
³ Haplotype Association - Find HLA haplotypes with this allele.
ª Notes - See notes for ambiguous combinations of alleles.

Allele frequency net database (AFND) 2020 update: gold-standard data classification, open access genotype data and new query tools
Gonzalez-Galarza FF, McCabe A, Santos EJ, Jones J, Takeshita LY, Ortega-Rivera ND, Del Cid-Pavon GM, Ramsbottom K, Ghattaoraya GS, Alfirevic A, Middleton D and Jones AR Nucleic Acid Research 2020, 48:D783-8.
Liverpool, U.K.

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