Allele Frequencies in World Populations

HLA Database Allele Report

The list below shows all populations in AFND that contains the allele. If an allele has an entry with a lower resolution this will be shown at the end.



Allele reported 64 time(s) and present in 62 population(s).

Population Phenotype
Frequency (%)
Distribution² Haplotype³
MEXMexico Hidalgo Mezquital Valley/ Otomi43.10.291772See
USAUSA San Francisco Caucasian0.2110220See
NIRIreland Northern33.90.18701000See
ENGEngland Blood Donors of Mixed Ethnicity30.90.1618519See
USAUSA Eastern European0.1610558See
MARMorocco Nador Metalsa pop 20.159073See
USAUSA Italy Ancestry0.1560273See
ESPSpain, Canary Islands, Gran canaria island29.30.1558215See
POLPoland BMR25.90.137323595See
MARMorocco Settat Chaouya27.20.136098See
MARMorocco Atlantic Coast Chaouya0.136098See
INDIndia Khandesh Region Pawra0.130050See
RUSRussia Bashkortostan, Tatars24.00.1198192See
INDIndia Karnataka Kannada Speaking21.80.1150174See
RUSRussia Nizhny Novgorod, Russians20.40.10931510See
LBNLebanon Mixed0.108097See
INDIndia Tamil Nadu Nadar0.107061See
BRABrazil Rio de Janeiro Caucasian0.1046521See
RUSRussia Belgorod region20.30.1046153See
RUSRussian Federation Vologda Region17.60.0966119See
SAUSaudi Arabia pop 6 (G)0.096628927See
BRABrazil Barra Mansa Rio State Caucasian0.0962405See
BRABrazil Rio de Janeiro Black0.093868See
CHLChile Huilliche NA-DHS_14 (G)18.80.093820See
MEXMexico Zapotec NA-DHS_7 (G)18.80.093820See
USAUSA Mexican American Mestizo0.0900553See
CRICosta Rica Guanacaste Mestizo (G)15.40.0860110See
RUSRussia Bashkortostan, Bashkirs15.80.0833120See
BRABrazil Barra Mansa Rio State Black0.078673See
CRICosta Rica African -Caribbean (G)15.60.0780102See
IRNIran Baloch0.0780100See
CRICosta Rica Central Valley Mestizo (G)14.10.0750221See
ZAFSouth African Mixed ancestry14.00.070050See
INDIndia West Coast Parsi0.070050See
INDIndia Kerala Malayalam speaking12.40.0660356See
USAUSA Spain Ancestry0.0650279See
NICNicaragua Mestizo (G)13.00.0650155See
BRABrazil Rio de Janeiro Parda0.0602170See
CANCanada Chipewyan NA-DHS_2 (G)12.00.060025See
SAUSaudi Arabia pop 58.20.0570158See
ZAFSouth African Black9.20.0563142See
CANCanada Cree NA-DHS_3 (G)11.10.055618See
CHNChina Jingpo Minority9.60.0530105See
USAUSA NMDP Black South or Central American0.04094889See
INDIndia Mumbai Maratha0.037091See
COLColombia Wayuu NA-DHS_15 (G)7.10.035715See
CANCanada Ojibwa NA-DHS_4 (G)6.70.033316See
RUSRussia Tundra Nentsi NA-DHS_1 (G)6.70.033316See
COLColombia Inga NA-DHS_11 (G)6.70.033316See
INDIndia West Bhil0.030050See
CHNChina North Han0.0290105See
CRICosta Rica Amerindians (G)5.80.0290125See
CRICosta Rica Cabecar NA-DHS_9 (G)5.30.026319See
MEXMexico Mixe NA-DHS_6 (G)5.00.025020See
BOLBolivia/Chile Aymara NA-DHS_13 (G)5.00.025020See
INDIndia Andhra Pradesh Telugu Speaking3.80.0188186See
ZAFSouth African Indian population2.00.010050See
CHNChina Guangdong Province Meizhou Han0.0100100See
VNMVietnam Kinh1.00.0050101See
CHNChina Zhejiang Han0.00171734See
USAUSA Arizona Gila River Pima0.00103000See
HKGHong Kong Chinese HKBMDR HLA 11 loci0.20.00095266See
CZECzech Republic0.0000106See
KORSouth Korea pop 30.0000485See

Frequency data at lower resolution for this allele can be found in links below

Allele  Number of Populations 


* Allele Frequency: Total number of copies of the allele in the population sample (Alleles / 2n) in decimal format.
   Important: This field has been expanded to four decimals to better represent frequencies of large datasets (e.g. where sample size > 1000 individuals)
* Phenotype Frequency: Percentage of individuals who have the allele or gene (Individuals / n).
* Allele Frequencies shown in green were calculated from Phenotype Frequencies assuming Hardy-Weinberg proportions.

¹ IMGT/HLA Database - For more details of the allele.
² Distribution - Graphical distribution of the allele.
³ Haplotype Association - Find HLA haplotypes with this allele.
ª Notes - See notes for ambiguous combinations of alleles.

Allele frequency net database (AFND) 2020 update: gold-standard data classification, open access genotype data and new query tools
Gonzalez-Galarza FF, McCabe A, Santos EJ, Jones J, Takeshita LY, Ortega-Rivera ND, Del Cid-Pavon GM, Ramsbottom K, Ghattaoraya GS, Alfirevic A, Middleton D and Jones AR Nucleic Acid Research 2020, 48:D783-8.
Liverpool, U.K.

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