Allele Frequencies in World Populations

HLA Database » Allele Report

The list below shows all populations in AFND that contains the allele. If an allele has an entry with a lower resolution this will be shown at the end.



Allele reported 205 time(s) and present in 179 population(s).

Population Phenotype
Frequency (%)
Distribution² Haplotype³
SGPSingapore SGVP Malay MAS0.112089See
INDIndia Mumbai Maratha0.099091See
MYSMalaysia Peninsular Malay16.60.0915951See
SGPSingapore Riau Malay0.0840132See
SGPSingapore Javaneses0.080051See
PHLPhilippines Ivatan14.00.070050See
KENKenya Nandi0.0650240See
THAThailand Northeast pop 20.0640400See
SGPSingapore Thai0.0600100See
TZATanzania Maasai10.30.0578336See
KENKenya Luo0.0510265See
CZECzech Republic0.0470106See
ZWEZimbabwe Harare Shona0.0420230See
USAUSA San Antonio Caucasian0.0364222See
ZAFSouth Africa Natal Tamil0.031051See
INDIndia Delhi pop 26.20.031090See
INDIndia West Coast Parsi0.030050See
ZAFSouth Africa Worcester6.00.0280159See
MYSMalaysia Peninsular Indian5.50.0277271See
CHESwitzerland Lugano0.02681169See
CHESwitzerland Sion0.0261832See
CHNChina Uyghur HIV negative0.026019See
CHNChina Inner Mongolia Region0.0250102See
AUSAustralia New South Wales Caucasian0.0250134See
LKASri Lanka Colombo4.90.0250714See
POLPoland DKMS0.025020653See
TURTurkey pop 50.0250142See
VNMVietnam Hanoi Kinh pop 20.0240170See
INDIndia Tamil Nadu0.02382492See
FRAFrance Southeast4.60.0230130See
CHESwitzerland Aargau-Solothurn0.02221838See
ZMBZambia Lusaka0.022044See
USAUSA Asian0.0220358See
USAUSA NMDP Southeast Asian0.021827978See
USAUSA Caucasian pop 20.0210265See
USAUSA San Francisco Caucasian0.0210220See
SGPSingapore SGVP Chinese CHS0.021096See
INDIndia South UCBB4.20.020911446See
INDIndia North UCBB4.20.02095849See
GRCGreece pop 60.0207242See
DEUGermany DKMS - Austria minority0.02061698See
DEUGermany DKMS - German donors0.02053456066See
GBRUnited Kingdom pop 34.00.0200604See
RUSRussia Tuva pop 20.0200169See
RUSRussia Karelia0.01991075See
DEUGermany pop 60.01998862See
USAUSA Caucasian pop 40.01961070See
DEUGermany DKMS - Netherlands minority0.01931374See
DEUGermany pop 80.019239689See
CZECzech Republic NMDR0.01915099See
CHESwitzerland Geneva0.019080See
USAUSA Hawaii Okinawa0.0190106See
USAUSA NMDP Filipino0.018950614See
CHESwitzerland Zurich0.01874875See
GRCGreece pop 83.60.018183See
CHESwitzerland Luzern0.01801553See
UGAUganda Kampala0.0180161See
CHESwitzerland Basel0.01791888See
PRTPortugal Azores Terceira Island3.50.0175130See
GEOGeorgia Tibilisi Kurd0.017031See
UGAUganda Kampala pop 20.0170175See
INDIndia West UCBB3.40.01695829See
INDIndia Central UCBB3.40.01694204See
INDIndia Northeast UCBB3.40.0169296See
DEUGermany DKMS - Croatia minority0.01682057See
DEUGermany DKMS - France minority0.01671406See
JPNJapan pop 10.0160560See
CHESwitzerland Geneva pop 20.01571267See
USAUSA NMDP South Asian Indian0.0155185391See
USAUSA NMDP European Caucasian0.01541242890See
FRAFrance West3.00.0151100See
CHNChina Beijing0.015067See
SDNSudan Mixed3.00.0150200See
USAUSA Philadelphia Caucasian3.10.0150141See
CHESwitzerland St Gallen0.01492113See
CHNChina Qinghai Province Hui0.0140110See
CHESwitzerland Bern0.01403545See
IRLIreland South2.80.0140250See
USAUSA NMDP Vietnamese0.014043540See
CHESwitzerland Graubunden0.0139759See
DEUGermany DKMS - Bosnia and Herzegovina minority0.01361028See
INDIndia East UCBB2.70.01352403See
DEUGermany DKMS - Italy minority0.01341159See
DEUGermany DKMS - Portugal minority0.01321176See
DEUGermany DKMS - Spain minority0.01311107See
ITAItaly North0.0130277See
NLDNetherlands Leiden0.01301305See
NIRIreland Northern2.60.01301000See
USAUSA San Diego2.60.0130496See
DEUGermany DKMS - Turkey minority0.01294856See
DEUGermany DKMS - Romania minority0.01261234See
DEUGermany DKMS - United Kingdom minority0.01251043See
AREUnited Arab Emirates Pop 10.0120570See
ITAItaly pop 50.0120975See
TWNTaiwan Han Chinese0.0120504See
USAUSA NMDP North American Amerindian0.011635791See
DEUGermany DKMS - Greece minority0.01161894See
USAUSA NMDP Middle Eastern or North Coast of Africa0.011170890See
USAUSA Hispanic0.0110234See
USAUSA NMDP American Indian South or Central America0.01105926See
USAUSA NMDP Caribean Indian0.011014339See
USAUSA Caucasian Bethesda2.30.0110307See
JPNJapan pop 30.01101018See
ITAItaly South0.0110141See
NZLNew Zealand Maori with Full Ancestry2.20.011046See
CHNChina North Han pop 20.0106567See
USAUSA Asian pop 20.01021772See
ZAFSouth Africa Caucasians0.0100102See
USAUSA African American0.0100252See
TWNTaiwan Minnan pop 12.00.0100102See
BFABurkina Faso Fulani0.010049See
NZLNew Zealand Maori with Admixed History1.90.0100105See
PAKPakistan Mixed Pathan0.0100100See
RUSRussia Transbaikal Territory Buryats2.00.0100150See
SAUSaudi Arabia Guraiat and Hail1.40.0100213See
KENKenya, Nyanza Province, Luo tribe2.00.0100100See
RUSRussia Bering Island Aleuts0.0096104See
USAUSA Hispanic pop 20.00951999See
USAUSA NMDP Japanese0.009424582See
JPNJapan pop 160.009318604See
USAUSA NMDP Caribean Hispanic0.0091115374See
JPNJapan pop 50.0090117See
JPNJapan Central0.0090371See
BRABrazil Mixed0.0090108See
CHNChina Canton Han0.0090264See
CHNChina South Han0.0090284See
GEOGeorgia Tibilisi0.0090109See
DEUGermany Essen1.70.0090174See
USAUSA NMDP Korean0.009077584See
USAUSA African American pop 40.00872411See
DEUGermany DKMS - China minority0.00861282See
USAUSA NMDP African0.008328557See
USAUSA North American Native0.0080187See
ESPSpain (Catalunya, Navarra, Extremadura, Aaragón, Cantabria,1.60.00804335See
ENGEngland North West1.70.0080298See
NLDNetherlands UMCU1.60.007864See
CHESwitzerland Lausanne0.0077993See
USAUSA NMDP Hawaiian or other Pacific Islander0.007611499See
ESPSpain Sevilla1.40.0072278See
USAUSA NMDP African American pop 20.0072416581See
CHNChina Hubei Han1.40.00713732See
AUSAustralia Groote Eylandt Aborigine0.007075See
MEXMexico Mexico City Mestizo population0.0070143See
USAUSA NMDP Chinese0.006499672See
USAUSA NMDP Alaska Native or Aleut0.00601376See
AUSAustralia Cape York Peninsula Aborigine0.0060103See
CHNChina Guizhou Province Miao pop 20.006085See
CHNChina Marrow Donor Registry0.0060600See
ESPSpain Andalusia0.006099See
ENGEngland London Ashkenazi Jews0.0060500See
HKGHong Kong Chinese BMDR0.00577595See
USAUSA NMDP Hispanic South or Central American0.0055146714See
NICNicaragua Managua1.10.0055339See
MYSMalaysia Peninsular Chinese1.00.0052194See
USAUSA NMDP Caribean Black0.005133328See
USAUSA African American Bethesda1.10.0050187See
KORSouth Korea pop 30.0050485See
LBNLebanon Mixed0.005097See
PAKPakistan Mixed Sindhi0.0050101See
CHNChina South Han pop 20.00501098See
CHNChina Guangzhou0.0050102See
USAUSA NMDP Mexican or Chicano0.0048261235See
COLColombia Bogotá Cord Blood0.90.00441463See
CHNChina Wuhan0.80.0040121See
RUSRussia North Ossetian0.80.0039127See
JPNJapan Kyoto and Osaka0.0030165See
CMRCameroon Beti0.0030174See
TWNTaiwan pop 20.0030364See
MEXMexico Mexico City Mestizo pop 20.0021234See
USAUSA Alaska Yupik0.0020252See
USAUSA South Texas Hispanic0.0000194See
MLIMali Bandiagara0.0000138See
MARMorocco Settat Chaouya0.00.000098See
MARMorocco Nador Metalsa pop 20.000073See
INDIndia West Bhil0.000050See
INDIndia Khandesh Region Pawra0.000050See
SCOScotland Orkney0.00.000099See
SENSenegal Niokholo Mandenka0.0000165See
SGPSingapore SGVP. Indian INS0.000086See
PAKPakistan Karachi Parsi0.000091See
PAKPakistan Baloch0.000066See
PAKPakistan Brahui0.0000104See
PAKPakistan Burusho0.000092See
PAKPakistan Kalash0.000069See
RUSRussia Nenet Mixed0.000055See
RUSRussia Arkhangelsk Pomor0.000063See
RUSRussia Murmansk Saomi Mixed0.000070See
CMRCameroon Sawa0.000013See
CMRCameroon Baka Pygmy0.000010See
CMRCameroon Bamileke0.000077See
CHNChina North Han0.0000105See
CHNChina Guizhou Province Bouyei0.0000109See
CHNChina Guizhou Province Shui0.0000153See
AUSAustralia Yuendumu Aborigine0.0000191See
BFABurkina Faso Mossi0.000053See
BFABurkina Faso Rimaibe0.000047See
BRABrazil Vale do Ribeira Quilombos0.00.0000144See

Frequency data at lower resolution for this allele can be found in links below

Allele  Number of Populations 


* Allele Frequency: Total number of copies of the allele in the population sample (Alleles / 2n) in decimal format.
   Important: This field has been expanded to four decimals to better represent frequencies of large datasets (e.g. where sample size > 1000 individuals)
* Phenotype Frequency: Percentage of individuals who have the allele or gene (Individuals / n).
* Allele Frequencies shown in green were calculated from Phenotype Frequencies assuming Hardy-Weinberg proportions.

¹ IMGT/HLA Database - For more details of the allele.
² Distribution - Graphical distribution of the allele.
³ Haplotype Association - Find HLA haplotypes with this allele.
ª Notes - See notes for ambiguous combinations of alleles.


Allele frequency net database (AFND) 2020 update: gold-standard data classification, open access genotype data and new query tools
Gonzalez-Galarza FF, McCabe A, Santos EJ, Jones J, Takeshita LY, Ortega-Rivera ND, Del Cid-Pavon GM, Ramsbottom K, Ghattaoraya GS, Alfirevic A, Middleton D and Jones AR Nucleic Acid Research 2020, 48:D783-8.
Liverpool, U.K.

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