Allele Frequencies in World Populations

HLA Database » Allele Report

The list below shows all populations in AFND that contains the allele. If an allele has an entry with a lower resolution this will be shown at the end.



Allele reported 128 time(s) and present in 98 population(s).

Population Phenotype
Frequency (%)
Distribution² Haplotype³
BRABrazil Puyanawa20.00.1000150See
COLColombia/Brazil Ticuna Arara NA-DHS_21 (G)7.10.071417See
CANCanada Ojibwa NA-DHS_4 (G)13.30.066716See
RUSRussia Tundra Nentsi NA-DHS_1 (G)13.30.066716See
USAUSA Arizona Gila River Amerindian0.0620492See
COLColombia/Brazil Ticuna Tarapaca NA-DHS_22 (G)11.80.058819See
CHNChina Guangdong Province Meizhou Han0.0560100See
BOLBolivia/Chile Aymara NA-DHS_13 (G)10.00.050020See
RUSRussia Bering Island Aleuts0.0433104See
COLColombia Inga NA-DHS_11 (G)6.70.033316See
CHNChina Han HIV negative0.031072See
CHNChina Henan HIV negative0.031016See
CHNChina Uyghur HIV negative0.026019See
JPNJapan pop 50.0260117See
BOLBolivia/Peru Quechua NA-DHS_12 (G)4.80.023821See
MEXMexico Chichen Itza Maya (prehispanic)0.021347See
JPNJapan Central0.0200371See
CHNChina North Han0.0190105See
USAUSA Alaska Yupik0.0190252See
RUSRussia Transbaikal Territory Buryats3.00.0170150See
CHNChina Inner Mongolia Region0.0150102See
MEXMexico Oaxaca Zapotec0.015090See
MEXMexico Tixcacaltuyub Maya0.014967See
CHNChina Qinghai Province Hui0.0140110See
JPNJapan pop 160.013618604See
USAUSA South Dakota Lakota Sioux0.0130302See
USAUSA NMDP Japanese0.012924582See
USAUSA NMDP Alaska Native or Aleut0.01201376See
JPNJapan pop 30.01201018See
CHNChina North Han pop 20.0115567See
JPNJapan pop 10.0110560See
CHNChina Jingpo Minority1.90.0100105See
MEXMexico Mexico City Mestizo pop 20.0085234See
DEUGermany DKMS - China minority0.00861282See
USAUSA NMDP Korean0.006677584See
INDIndia Delhi pop 21.20.006090See
KORSouth Korea pop 30.0060485See
JPNJapan Kyoto and Osaka0.0060165See
CHNChina Tibet Region Tibetan0.0060158See
MYSMalaysia Peninsular Malay1.20.0058951See
CHNChina Hubei Han1.10.00553732See
MYSMalaysia Peninsular Chinese1.00.0052194See
SGPSingapore SGVP Chinese CHS0.005096See
TWNTaiwan pop 20.0050364See
USAUSA North American Native0.0050187See
CHNChina Marrow Donor Registry0.0050600See
CHLChile Santiago Mixed1.00.005070See
USAUSA Asian pop 20.00451772See
USAUSA NMDP North American Amerindian0.004435791See
USAUSA Caucasian Bethesda0.80.0040307See
USAUSA NMDP American Indian South or Central America0.00405926See
USAUSA NMDP Chinese0.004099672See
MEXMexico Mexico City Mestizo population0.0035143See
USAUSA NMDP Hispanic South or Central American0.0033146714See
CHNChina South Han pop 20.00321098See
RUSRussia Karelia0.00281075See
USAUSA Hispanic pop 20.00251999See
COLColombia Bogotá Cord Blood0.50.00241463See
USAUSA NMDP Southeast Asian0.002327978See
HKGHong Kong Chinese BMDR0.00227595See
INDIndia South UCBB0.50.002211446See
CHESwitzerland Luzern0.00201553See
USAUSA NMDP Vietnamese0.001943540See
CHESwitzerland Basel0.00191888See
DEUGermany DKMS - Croatia minority0.00192057See
USAUSA NMDP South Asian Indian0.0018185391See
MYSMalaysia Peninsular Indian0.40.0018271See
NICNicaragua Managua0.40.0018339See
ESPSpain Sevilla0.40.0018278See
INDIndia Central UCBB0.40.00184204See
INDIndia North UCBB0.30.00175849See
USAUSA NMDP Mexican or Chicano0.0016261235See
INDIndia West UCBB0.30.00155829See
POLPoland DKMS0.001420653See
DEUGermany DKMS - Romania minority0.00121234See
INDIndia East UCBB0.20.00102403See
AREUnited Arab Emirates Pop 10.0010570See
USAUSA NMDP Caribean Indian0.001014339See
USAUSA Eastern European0.0010558See
USAUSA Mexican American Mestizo0.0010553See
DEUGermany DKMS - Turkey minority0.00094856See
INDIndia Tamil Nadu0.00082492See
CZECzech Republic NMDR0.00065099See
USAUSA NMDP Caribean Hispanic0.0006115374See
USAUSA NMDP European Caucasian0.00041242890See
DEUGermany DKMS - Portugal minority0.00041176See
DEUGermany DKMS - France minority0.00041406See
USAUSA NMDP Middle Eastern or North Coast of Africa0.000370890See
DEUGermany pop 80.000339689See
DEUGermany pop 60.00048862See
USAUSA NMDP Hawaiian or other Pacific Islander0.000211499See
USAUSA African American pop 40.00022411See
ESPSpain (Catalunya, Navarra, Extremadura, Aaragón, Cantabria,0.10.00024335See
DEUGermany DKMS - German donors0.00023456066See
USAUSA NMDP Filipino0.000250614See
USAUSA NMDP Caribean Black0.000133328See
USAUSA NMDP African American pop 20.0001416581See
USAUSA San Antonio Caucasian0.0000222See
USAUSA South Texas Hispanic0.0000194See
NIRIreland Northern0.00.00001000See
NLDNetherlands Leiden0.00001305See
SGPSingapore SGVP. Indian INS0.000086See
SGPSingapore SGVP Malay MAS0.000089See
SENSenegal Niokholo Mandenka0.0000165See
USAUSA Caucasian pop 20.0000265See
USAUSA African American0.0000252See
USAUSA Hispanic0.0000234See
USAUSA African American Bethesda0.00.0000187See
USAUSA Philadelphia Caucasian0.00.0000141See
USAUSA Asian0.0000358See
FRAFrance West0.00.0000100See
GBRUnited Kingdom pop 30.00.0000604See
IRNIran Tehran0.0000120See
LBNLebanon Mixed0.000097See
MARMorocco Settat Chaouya0.00.000098See
MARMorocco Nador Metalsa pop 20.000073See
MEXMexico Oaxaca Mixtec0.0000103See
CHESwitzerland St Gallen0.00002113See
CHESwitzerland Sion0.0000832See
CHESwitzerland Zurich0.00004875See
CHESwitzerland Geneva pop 20.00001267See
CHESwitzerland Graubunden0.0000759See
CHESwitzerland Lugano0.00001169See
CHESwitzerland Lausanne0.0000993See
CHESwitzerland Geneva0.000080See
CHESwitzerland Aargau-Solothurn0.00001838See
CHESwitzerland Bern0.00003545See

Frequency data at lower resolution for this allele can be found in links below

Allele  Number of Populations 


* Allele Frequency: Total number of copies of the allele in the population sample (Alleles / 2n) in decimal format.
   Important: This field has been expanded to four decimals to better represent frequencies of large datasets (e.g. where sample size > 1000 individuals)
* Phenotype Frequency: Percentage of individuals who have the allele or gene (Individuals / n).
* Allele Frequencies shown in green were calculated from Phenotype Frequencies assuming Hardy-Weinberg proportions.

¹ IMGT/HLA Database - For more details of the allele.
² Distribution - Graphical distribution of the allele.
³ Haplotype Association - Find HLA haplotypes with this allele.
ª Notes - See notes for ambiguous combinations of alleles.


Allele frequency net database (AFND) 2020 update: gold-standard data classification, open access genotype data and new query tools
Gonzalez-Galarza FF, McCabe A, Santos EJ, Jones J, Takeshita LY, Ortega-Rivera ND, Del Cid-Pavon GM, Ramsbottom K, Ghattaoraya GS, Alfirevic A, Middleton D and Jones AR Nucleic Acid Research 2020, 48:D783-8.
Liverpool, U.K.

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