Allele Frequencies in World Populations

HLA Database » Allele Report

The list below shows all populations in AFND that contains the allele. If an allele has an entry with a lower resolution this will be shown at the end.



Allele reported 230 time(s) and present in 220 population(s).

Population Phenotype
Frequency (%)
Distribution² Haplotype³
COLColombia North Chimila Amerindians0.468047See
AUSAustralia Kimberly Aborigine0.286041See
BGRBulgaria Romani0.273013See
PNGPapua New Guinea Wosera Abelam0.2320131See
AUSAustralia Yuendumu Aborigine0.2030191See
GEOGeorgia Tibilisi Kurd0.155031See
ESPSpain Andalusia Romani0.147099See
AUSAustralia Groote Eylandt Aborigine0.137075See
INDIndia West UCBB22.80.11425829See
AREUnited Arab Emirates Pop 10.1140570See
INDIndia Central UCBB22.20.11124204See
NZLNew Zealand Polynesians with Admixed History18.50.111027See
INDIndia North UCBB21.60.10805849See
USAUSA NMDP South Asian Indian0.1077185391See
INDIndia South UCBB21.10.105311446See
SGPSingapore SGVP. Indian INS0.105086See
CHNChina Uyghur HIV negative0.105019See
ZAFSouth Africa Natal Tamil0.104051See
INDIndia Tamil Nadu0.10382492See
PNGPapua New Guinea Karimui Plateau Pawaia0.100080See
MYSMalaysia Peninsular Indian18.10.0996271See
INDIndia East UCBB19.50.09762403See
NZLNew Zealand Polynesians with Full Ancestry14.30.095021See
PHLPhilippines Ivatan16.00.090050See
SAUSaudi Arabia Guraiat and Hail15.20.0880213See
LKASri Lanka Colombo16.00.0850714See
USAUSA NMDP Southeast Asian0.082927978See
PNGPapua New Guinea West Schrader Ranges Haruai0.074055See
ISRIsrael Arab Druze0.0700101See
RUSRussia Tuva pop 20.0690169See
ITAItaly North0.0690277See
USAUSA NMDP Filipino0.068150614See
RUSRussia Transbaikal Territory Buryats13.00.0670150See
AUSAustralia Cape York Peninsula Aborigine0.0670103See
GRCGreece pop 812.10.066383See
IRNIran Gorgan0.062564See
INDIndia Delhi pop 211.10.062090See
USAUSA New Mexico Canoncito Navajo0.061042See
INDIndia Northeast UCBB12.20.0608296See
USAUSA NMDP Hawaiian or other Pacific Islander0.058011499See
PRTPortugal Azores Terceira Island11.40.0570130See
NCLNew Caledonia0.056065See
CHESwitzerland St Gallen0.05492113See
CHNChina Inner Mongolia Region0.0540102See
CHESwitzerland Sion0.0535832See
ITAItaly pop 50.0530975See
NZLNew Zealand Maori with Admixed History9.50.0520105See
PRTAzores Terceira Island0.0510130See
TWNTaiwan Bunun8.90.0500101See
CHNChina Qinghai Province Hui0.0500110See
LBNLebanon Mixed0.050097See
SGPSingapore Javaneses0.050051See
BRABrazil Puyanawa10.00.0500150See
CHESwitzerland Zurich0.04974875See
USAUSA Asian pop 20.04971772See
GRCGreece pop 60.0496242See
DEUGermany DKMS - Turkey minority0.04944856See
CHESwitzerland Bern0.04923545See
DEUGermany DKMS - Greece minority0.04921894See
TWNTaiwan Minnan pop 18.80.0490102See
CHESwitzerland Aargau-Solothurn0.04641838See
CHNChina Beijing0.046067See
VENVenezuela Perja Mountain Bari0.045055See
JORJordan Amman0.0450146See
CHESwitzerland Lugano0.04471169See
MEXMexico Chiapas Lacandon Mayans0.0436218See
USAUSA NMDP North American Amerindian0.043535791See
COLColombia Bogotá Cord Blood8.20.04241463See
IRNIran Tehran0.0420120See
CHESwitzerland Luzern0.04141553See
TWNTaiwan Han Chinese0.0410504See
CHESwitzerland Lausanne0.0406993See
DEUGermany DKMS - Croatia minority0.04012057See
USAUSA NMDP Caribean Indian0.040014339See
DEUGermany DKMS - Romania minority0.03981234See
CHNChina North Han pop 20.0397567See
USAUSA NMDP Hispanic South or Central American0.0393146714See
CHESwitzerland Geneva pop 20.03911267See
USAUSA South Texas Hispanic0.0390194See
MEXMexico Oaxaca Mixe0.038055See
CHNChina Canton Han0.0380264See
USAUSA NMDP Caribean Hispanic0.0375115374See
USAUSA NMDP Middle Eastern or North Coast of Africa0.037270890See
CHESwitzerland Basel0.03701888See
CHNChina South Han0.0370284See
DEUGermany DKMS - Portugal minority0.03701176See
DEUGermany DKMS - China minority0.03671282See
USAUSA Hispanic0.0360234See
USAUSA NMDP American Indian South or Central America0.03605926See
USAUSA NMDP Mexican or Chicano0.0355261235See
PNGPapua New Guinea Eastern Highlands Goroka Asaro0.035057See
SENSenegal Niokholo Mandenka0.0340165See
USAUSA San Diego6.40.0340496See
BRABrazil Mixed0.0330108See
THAThailand Northeast pop 20.0330400See
TWNTaiwan pop 20.0330364See
ITAItaly South0.0320141See
CHNChina Marrow Donor Registry0.0320600See
SGPSingapore SGVP Chinese CHS0.032096See
CHNChina Hubei Han6.20.03123732See
DEUGermany DKMS - Bosnia and Herzegovina minority0.03121028See
CHNChina Han HIV negative0.031072See
CHNChina Henan HIV negative0.031016See
JPNJapan pop 160.030818604See
USAUSA Hispanic pop 20.03051999See
CHLChile Santiago Mixed6.00.030470See
DEUGermany DKMS - Spain minority0.03031107See
ESPSpain Andalusia0.030099See
ESPSpain Gipuzkoa Basque0.0300100See
USAUSA Hawaii Okinawa0.0290106See
CHNChina Sichuan HIV negative0.029034See
VNMVietnam Hanoi Kinh pop 20.0290170See
MEXMexico Oaxaca Mixtec0.0290103See
ZAFSouth Africa Caucasians0.0290102See
AREUnited Arab Emirates Abu Dhabi0.028852See
CHNChina South Han pop 20.02871098See
ESPSpain (Catalunya, Navarra, Extremadura, Aaragón, Cantabria,5.60.02834335See
DEUGermany DKMS - Italy minority0.02831159See
SDNSudan Mixed5.50.0280200See
GEOGeorgia Tibilisi0.0280109See
RUSRussia North Ossetian5.50.0276127See
DEUGermany DKMS - Austria minority0.02751698See
USAUSA San Antonio Caucasian0.0273222See
MYSMalaysia Peninsular Malay5.40.0273951See
USAUSA Asian0.0270358See
TWNTaiwan Pazeh5.50.027055See
JPNJapan Central0.0270371See
FRAFrance Southeast5.40.0270130See
INDIndia New Delhi0.027071See
HKGHong Kong Chinese BMDR0.02697595See
DEUGermany pop 80.026239689See
KORSouth Korea pop 30.0260485See
USAUSA Caucasian Bethesda5.30.0260307See
USAUSA Philadelphia Caucasian4.10.0260141See
JPNJapan pop 30.02601018See
USAUSA NMDP Chinese0.025699672See
DEUGermany DKMS - France minority0.02561406See
ESPSpain Sevilla5.00.0252278See
NLDNetherlands Leiden0.02501305See
CHESwitzerland Geneva0.025080See
USAUSA NMDP Alaska Native or Aleut0.02401376See
DEUGermany pop 60.02348862See
MYSMalaysia Peninsular Chinese4.60.0232194See
ENGEngland North West4.70.0230298See
SGPSingapore Riau Malay0.0230132See
MEXMexico Chihuahua Tarahumara0.023044See
ESPSpain Catalonia Girona0.023088See
DEUGermany DKMS - German donors0.02273456066See
USAUSA NMDP European Caucasian0.02231242890See
JPNJapan pop 10.0220560See
NZLNew Zealand Maori with Full Ancestry4.30.022046See
MEXMexico Oaxaca Zapotec0.022090See
MEXMexico Chichen Itza Maya (prehispanic)0.021347See
USAUSA San Francisco Caucasian0.0210220See
GBRUnited Kingdom pop 34.10.0210604See
RUSRussia Karelia0.02051075See
CHNChina Yunnan Hani0.0200150See
CHNChina Yunnan Province Han0.0200101See
DEUGermany DKMS - Netherlands minority0.02001374See
CHNChina Guangzhou0.0200102See
TWNTaiwan Tsou3.90.020051See
TWNTaiwan Paiwan3.90.020051See
USAUSA NMDP Japanese0.019624582See
USAUSA NMDP Korean0.019377584See
CZECzech Republic NMDR0.01935099See
MEXMexico Mexico City Mestizo pop 20.0192234See
USAUSA Eastern European0.0190558See
USAUSA Caucasian pop 20.0190265See
POLPoland DKMS0.018720653See
USAUSA NMDP Vietnamese0.018643540See
NICNicaragua Managua3.70.0183339See
PNGPapua New Guinea East New Britain Rabaul0.018060See
JPNJapan pop 50.0170117See
USAUSA Alaska Yupik0.0170252See
SGPSingapore SGVP Malay MAS0.017089See
DEUGermany DKMS - United Kingdom minority0.01651043See
CHNChina Guizhou Province Shui0.0160153See
SGPSingapore Thai0.0160100See
NLDNetherlands UMCU3.10.015664See
AUSAustralia New South Wales Caucasian0.0150134See
RUSRussia Bering Island Aleuts0.0144104See
PNGPapua New Guinea Wanigela Keapara0.014066See
USAUSA Caucasian pop 40.01401070See
CHESwitzerland Graubunden0.0122759See
UGAUganda Kampala0.0120161See
BRABrazil Terena1.00.011060See
USAUSA African American Bethesda2.10.0110187See
FRAFrance West2.00.0100100See
TWNTaiwan Saisiat2.00.010051See
TWNTaiwan Rukai2.00.010050See
TWNTaiwan Siraya2.00.010051See
COLColombia North Wiwa El Encanto0.009652See
TWNTaiwan Hakka1.80.009055See
PNGPapua New Guinea Madang0.009065See
JPNJapan Kyoto and Osaka0.0090165See
IRLIreland South1.60.0080250See
CHNChina Southwest Dai0.0080124See
MEXMexico Mexico City Mestizo population0.0070143See
USAUSA NMDP Caribean Black0.006433328See
ZAFSouth Africa Worcester1.00.0060159See
USAUSA Arizona Gila River Amerindian0.0060492See
KENKenya Nandi0.0060240See
USAUSA NMDP African American pop 20.0054416581See
USAUSA African American pop 40.00542411See
CHNChina Guizhou Province Bouyei0.0050109See
TWNTaiwan Ami1.00.005098See
ISRIsrael Ashkenazi and Non Ashkenazi Jews0.0050146See
USAUSA NMDP African0.004428557See
SAUSaudi Arabia pop 50.60.0032158See
KENKenya Luo0.0020265See
USAUSA African American0.0020252See
TZATanzania Maasai0.30.0016336See
BRABrazil Vale do Ribeira Quilombos0.00.0000144See
USAUSA North American Native0.0000187See
MLIMali Bandiagara0.0000138See
TWNTaiwan Puyuma0.00.000050See
TWNTaiwan Tao0.00.000050See
TWNTaiwan Atayal0.00.0000106See
TWNTaiwan Taroko0.00.000055See
TWNTaiwan Thao0.00.000030See
CHNChina North Han0.0000105See
ZMBZambia Lusaka0.000044See
CHNChina Guizhou Province Miao pop 20.000085See

Frequency data at lower resolution for this allele can be found in links below

Allele  Number of Populations 


* Allele Frequency: Total number of copies of the allele in the population sample (Alleles / 2n) in decimal format.
   Important: This field has been expanded to four decimals to better represent frequencies of large datasets (e.g. where sample size > 1000 individuals)
* Phenotype Frequency: Percentage of individuals who have the allele or gene (Individuals / n).
* Allele Frequencies shown in green were calculated from Phenotype Frequencies assuming Hardy-Weinberg proportions.

¹ IMGT/HLA Database - For more details of the allele.
² Distribution - Graphical distribution of the allele.
³ Haplotype Association - Find HLA haplotypes with this allele.
ª Notes - See notes for ambiguous combinations of alleles.


Allele frequency net database (AFND) 2020 update: gold-standard data classification, open access genotype data and new query tools
Gonzalez-Galarza FF, McCabe A, Santos EJ, Jones J, Takeshita LY, Ortega-Rivera ND, Del Cid-Pavon GM, Ramsbottom K, Ghattaoraya GS, Alfirevic A, Middleton D and Jones AR Nucleic Acid Research 2020, 48:D783-8.
Liverpool, U.K.

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