Allele Frequencies in World Populations

HLA Database Allele Report

The list below shows all populations in AFND that contains the allele. If an allele has an entry with a lower resolution this will be shown at the end.



Allele reported 35 time(s) and present in 35 population(s).

Population Phenotype
Frequency (%)
Distribution² Haplotype³
CHLChile Easter Island0.095021See
USAUSA African American pop 30.0940564See
CHLChile Huilliche NA-DHS_14 (G)12.50.093820See
ZAFSouth African Black12.70.0704142See
CRICosta Rica African -Caribbean (G)12.80.0690102See
BRABrazil Rio de Janeiro Caucasian0.0688521See
BRABrazil Rio de Janeiro Parda0.0556170See
NICNicaragua Mestizo (G)10.40.0520155See
CRICosta Rica Guanacaste Mestizo (G)9.10.0500110See
BRABrazil Barra Mansa Rio State Black0.050073See
BRABrazil Barra Mansa Rio State Caucasian0.0488405See
ENGEngland North West9.10.0450298See
USAUSA Mexican American Mestizo0.0450553See
USAUSA San Francisco Caucasian0.0420220See
ZAFSouth African Mixed ancestry8.00.040050See
ESPSpain, Canary Islands, Gran canaria island7.90.0395215See
ENGEngland Blood Donors of Mixed Ethnicity7.20.0356519See
CANCanada Ojibwa NA-DHS_4 (G)6.70.033316See
CRICosta Rica Amerindians (G)6.60.0330125See
BRABrazil Rio de Janeiro Black0.031268See
GTMGuatemala Kaqchikel NA-DHS_8 (G)5.30.026319See
CRICosta Rica Central Valley Mestizo (G)4.60.0230221See
USAUSA Italy Ancestry0.0220273See
MEXMexico Hidalgo Mezquital Valley/ Otomi2.80.013972See
POLPoland BMR2.70.013523595See
SAUSaudi Arabia pop 6 (G)0.013328927See
RUSRussia Bashkortostan, Tatars2.10.0104192See
ZAFSouth African Indian population2.00.010050See
USAUSA Spain Ancestry0.0090279See
RUSRussia Nizhny Novgorod, Russians1.40.00701510See
SAUSaudi Arabia pop 51.30.0063158See
RUSRussian Federation Vologda Region0.80.0042119See
RUSRussia Belgorod region0.70.0033153See
USAUSA Arizona Gila River Pima0.00193000See
HKGHong Kong Chinese HKBMDR HLA 11 loci0.10.00035266See

Frequency data at lower resolution for this allele can be found in links below

Allele  Number of Populations 


* Allele Frequency: Total number of copies of the allele in the population sample (Alleles / 2n) in decimal format.
   Important: This field has been expanded to four decimals to better represent frequencies of large datasets (e.g. where sample size > 1000 individuals)
* Phenotype Frequency: Percentage of individuals who have the allele or gene (Individuals / n).
* Allele Frequencies shown in green were calculated from Phenotype Frequencies assuming Hardy-Weinberg proportions.

¹ IMGT/HLA Database - For more details of the allele.
² Distribution - Graphical distribution of the allele.
³ Haplotype Association - Find HLA haplotypes with this allele.
ª Notes - See notes for ambiguous combinations of alleles.

Allele frequency net database (AFND) 2020 update: gold-standard data classification, open access genotype data and new query tools
Gonzalez-Galarza FF, McCabe A, Santos EJ, Jones J, Takeshita LY, Ortega-Rivera ND, Del Cid-Pavon GM, Ramsbottom K, Ghattaoraya GS, Alfirevic A, Middleton D and Jones AR Nucleic Acid Research 2020, 48:D783-8.
Liverpool, U.K.

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