Allele Frequencies in World Populations

HLA Database » Allele Report

The list below shows all populations in AFND that contains the allele. If an allele has an entry with a lower resolution this will be shown at the end.



Allele reported 192 time(s) and present in 165 population(s).

Population Phenotype
Frequency (%)
Distribution² Haplotype³
CMRCameroon Bakola Pygmy32.00.175350See
ZMBZambia Lusaka0.156044See
BFABurkina Faso Mossi0.151053See
MLIMali Bandiagara0.1430138See
GHAGhana Ga-Adangbe25.20.1336131See
KENKenya, Nyanza Province, Luo tribe24.00.1300100See
BFABurkina Faso Rimaibe0.106047See
KENKenya Nandi0.1020240See
KENKenya Luo0.0870265See
ZWEZimbabwe Harare Shona0.0820230See
USAUSA African American pop 30.0820564See
CMRCameroon Sawa0.077013See
USAUSA African American pop 40.07362411See
USAUSA NMDP African0.071528557See
LBNLebanon Mixed0.071097See
UGAUganda Kampala pop 20.0690175See
TZATanzania Maasai13.10.0688336See
USAUSA NMDP African American pop 20.0681416581See
USAUSA NMDP Caribean Black0.067933328See
USAUSA African American0.0600252See
USAUSA African American Bethesda11.70.0580187See
USAUSA Spain Ancestry0.0560279See
ISRIsrael Arab Druze0.0550101See
ZAFSouth Africa Worcester9.00.0530159See
GTMGuatemala Kaqchikel NA-DHS_8 (G)10.50.052619See
CMRCameroon Bamileke0.052077See
CMRCameroon Baka Pygmy0.050010See
AREUnited Arab Emirates Pop 10.0460570See
SDNSudan Mixed9.00.0450200See
CAFCentral African Republic Mbenzele Pygmy8.00.040836See
CMRCameroon Beti0.0400174See
ENGEngland London Ashkenazi Jews0.0380500See
MARMorocco Atlantic Coast Chaouya0.036098See
MARMorocco Settat Chaouya7.20.036098See
USAUSA NMDP Middle Eastern or North Coast of Africa0.033870890See
CANCanada Ojibwa NA-DHS_4 (G)6.70.033316See
BRABrazil Mixed0.0330108See
USAUSA NMDP Caribean Hispanic0.0299115374See
USAUSA NMDP Caribean Indian0.029014339See
UGAUganda Kampala0.0280161See
CRICosta Rica Cabecar NA-DHS_9 (G)5.30.026319See
CHNChina Uyghur HIV negative0.026019See
USAUSA Philadelphia Caucasian4.10.0260141See
BOLBolivia/Chile Aymara NA-DHS_13 (G)5.00.025020See
ESPSpain Andalusia0.024099See
USAUSA Hispanic pop 20.02251999See
PAKPakistan Karachi Parsi0.022091See
COLColombia North Chimila Amerindians0.021247See
ISRIsrael Ashkenazi and Non Ashkenazi Jews0.0210146See
USAUSA NMDP Hispanic South or Central American0.0200146714See
BFABurkina Faso Fulani0.020049See
DEUGermany DKMS - Turkey minority0.01964856See
AREUnited Arab Emirates Abu Dhabi0.019252See
ESPSpain, Canary Islands, Gran canaria island3.70.0186215See
RUSRussia Karelia0.01821075See
INDIndia New Delhi0.018071See
USAUSA Italy Ancestry0.0180273See
POLPoland DKMS0.017120653See
NICNicaragua Managua3.30.0165339See
DEUGermany DKMS - Italy minority0.01641159See
IRNIran Baloch0.0160100See
ITAItaly Bergamo3.00.0160101See
USAUSA San Diego2.90.0160496See
NLDNetherlands UMCU3.10.015664See
DEUGermany DKMS - Romania minority0.01541234See
COLColombia Bogotá Cord Blood3.00.01541463See
INDIndia North pop 20.015072See
PAKPakistan Mixed Pathan0.0150100See
USAUSA Mexican American Mestizo0.0150553See
USAUSA Caucasian pop 20.0150265See
DEUGermany DKMS - Greece minority0.01481894See
RUSRussia Bering Island Aleuts0.0144104See
USAUSA NMDP Mexican or Chicano0.0144261235See
PRTPortugal Azores Terceira Island2.60.0132130See
USAUSA South Texas Hispanic0.0130194See
ESPSpain (Catalunya, Navarra, Extremadura, Aaragón, Cantabria,2.40.01214335See
SGPSingapore SGVP. Indian INS0.012086See
PRTAzores Terceira Island0.0120130See
FRAFrance Southeast2.30.0120130See
USAUSA NMDP American Indian South or Central America0.01205926See
DEUGermany DKMS - Austria minority0.01181698See
DEUGermany DKMS - Bosnia and Herzegovina minority0.01141028See
DEUGermany DKMS - United Kingdom minority0.01101043See
DEUGermany DKMS - Portugal minority0.01111176See
ITAItaly South0.0110141See
ESPSpain Majorca and Minorca0.011090See
USAUSA North American Native0.0110187See
MEXMexico Mexico City Mestizo population0.0105143See
DEUGermany DKMS - France minority0.01031406See
GRCGreece pop 60.0103242See
DEUGermany pop 80.010139689See
FRAFrance Corsica Island0.0100100See
JORJordan Amman0.0100146See
SAUSaudi Arabia Guraiat and Hail8.10.0100213See
USAUSA Eastern European0.0100558See
USAUSA Hispanic0.0090234See
PRTPortugal Center pop 20.0090562See
GEOGeorgia Tibilisi0.0090109See
DEUGermany Essen1.70.0090174See
DEUGermany DKMS - German donors0.00893456066See
USAUSA NMDP European Caucasian0.00881242890See
USAUSA NMDP Hawaiian or other Pacific Islander0.008411499See
USAUSA Caucasian pop 40.00841070See
DEUGermany DKMS - Netherlands minority0.00841374See
USAUSA NMDP North American Amerindian0.008235791See
USAUSA Caucasian Bethesda1.50.0080307See
MARMorocco Nador Metalsa pop 20.008073See
ITAItaly pop 50.0080975See
RUSRussia North Ossetian1.60.0079127See
DEUGermany pop 60.00768862See
MEXMexico Tixcacaltuyub Maya0.007567See
ESPSpain Sevilla1.40.0072278See
BRABrazil Puyanawa1.30.0070150See
USAUSA San Francisco Caucasian0.0070220See
INDIndia North UCBB1.40.00695849See
DEUGermany DKMS - Spain minority0.00681107See
DEUGermany DKMS - Croatia minority0.00612057See
GRCGreece pop 81.20.006083See
IRLIreland South1.20.0060250See
INDIndia Delhi pop 21.20.006090See
ESPSpain Catalonia Girona0.006088See
CHNChina North Han pop 20.0053567See
FRAFrance West1.00.0050100See
CHLChile Santiago Mixed1.00.005070See
ZAFSouth Africa Caucasians0.0050102See
ITAItaly North0.0050277See
ITAItaly Sardinia pop30.0050100See
USAUSA NMDP Southeast Asian0.004327978See
CZECzech Republic NMDR0.00435099See
NIRIreland Northern0.80.00401000See
NLDNetherlands Leiden0.00401305See
GBRUnited Kingdom pop 30.80.0040604See
USAUSA NMDP South Asian Indian0.0039185391See
INDIndia Central UCBB0.60.00324204See
MYSMalaysia Peninsular Malay0.60.0032951See
USAUSA Asian0.0030358See
DEUGermany DKMS - China minority0.00271282See
MEXMexico Chiapas Lacandon Mayans0.0023218See
MEXMexico Mexico City Mestizo pop 20.0021234See
ENGEngland North West0.30.0020298See
USAUSA NMDP Alaska Native or Aleut0.00201376See
INDIndia West UCBB0.40.00205829See
INDIndia Tamil Nadu0.00182492See
INDIndia Northeast UCBB0.30.0017296See
USAUSA Asian pop 20.00141772See
USAUSA NMDP Filipino0.001450614See
TWNTaiwan pop 20.0010364See
LKASri Lanka Colombo0.30.0010714See
INDIndia East UCBB0.20.00082403See
CHNChina Hubei Han0.20.00083732See
USAUSA NMDP Vietnamese0.000743540See
INDIndia South UCBB0.10.000711446See
USAUSA NMDP Japanese0.000724582See
CHNChina South Han pop 20.00051098See
USAUSA NMDP Chinese0.000599672See
HKGHong Kong Chinese BMDR0.00027595See
USAUSA NMDP Korean0.000277584See
JPNJapan pop 160.000118604See
KORSouth Korea pop 30.0000485See
RUSRussia Nenet Mixed0.000055See
PHLPhilippines Ivatan0.00.000050See
ESPSpain Gipuzkoa Basque0.0000100See
SGPSingapore SGVP Chinese CHS0.000096See
SGPSingapore SGVP Malay MAS0.000089See
TWNTaiwan Minnan pop 10.00.0000102See
TWNTaiwan Hakka0.00.000055See
TWNTaiwan Atayal0.00.0000106See
TWNTaiwan Taroko0.00.000055See
TWNTaiwan Saisiat0.00.000051See
TWNTaiwan Bunun0.00.0000101See
TWNTaiwan Tsou0.00.000051See
TWNTaiwan Rukai0.00.000050See
TWNTaiwan Paiwan0.00.000051See
TWNTaiwan Ami0.00.000098See
TWNTaiwan Puyuma0.00.000050See
TWNTaiwan Tao0.00.000050See
TWNTaiwan Pazeh0.00.000055See
TWNTaiwan Siraya0.00.000051See
TWNTaiwan Thao0.00.000030See
CHNChina Tibet Region Tibetan0.0000158See
CHNChina North Han0.0000105See
AUSAustralia Yuendumu Aborigine0.0000191See
AUSAustralia New South Wales Caucasian0.0000134See
BRABrazil Vale do Ribeira Quilombos0.10.0000144See
USAUSA San Antonio Caucasian0.0000222See
USAUSA Alaska Yupik0.0000252See

Frequency data at lower resolution for this allele can be found in links below

Allele  Number of Populations 


* Allele Frequency: Total number of copies of the allele in the population sample (Alleles / 2n) in decimal format.
   Important: This field has been expanded to four decimals to better represent frequencies of large datasets (e.g. where sample size > 1000 individuals)
* Phenotype Frequency: Percentage of individuals who have the allele or gene (Individuals / n).
* Allele Frequencies shown in green were calculated from Phenotype Frequencies assuming Hardy-Weinberg proportions.

¹ IMGT/HLA Database - For more details of the allele.
² Distribution - Graphical distribution of the allele.
³ Haplotype Association - Find HLA haplotypes with this allele.
ª Notes - See notes for ambiguous combinations of alleles.


Allele frequency net database (AFND) 2020 update: gold-standard data classification, open access genotype data and new query tools
Gonzalez-Galarza FF, McCabe A, Santos EJ, Jones J, Takeshita LY, Ortega-Rivera ND, Del Cid-Pavon GM, Ramsbottom K, Ghattaoraya GS, Alfirevic A, Middleton D and Jones AR Nucleic Acid Research 2020, 48:D783-8.
Liverpool, U.K.

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