Allele Frequencies in World Populations

HLA Database Allele Report

The list below shows all populations in AFND that contains the allele. If an allele has an entry with a lower resolution this will be shown at the end.



Allele reported 147 time(s) and present in 106 population(s).

Population Phenotype
Frequency (%)
Distribution² Haplotype³
CHNChina Yunnan Province Dai0.176074See
CHNChina Guizhou Province Miao0.113085See
SGPSingapore SGVP Chinese CHS0.101096See
CHNChina Shanghai pop 20.100040See
ESPSpain Navarre Basques0.0990116See
CHNChina Canton Han0.0930264See
THAThailand East Chanthaburi Khmer0.090083See
ESPSpain Gipuzkoa Basque0.0860100See
TWNTaiwan Han Chinese0.0850504See
IDNIndonesia Java0.078058See
THAThailand Kamphaeng Phet0.077097See
CHNChina Yunnan Province Yao0.076066See
JPNJapan Hyogo13.30.075032See
CHNChina Zhejiang Han pop 20.0720833See
HKGHong Kong Chinese HKBMDR. DQ and DP13.70.07001064See
CHNChina Yunnan Province Nu pop 20.069072See
THAThailand Bangkok0.0630104See
THAThailand Northeast0.061066See
CHNChina Beijing Han0.0610180See
CHNChina Lijiang Naxi0.0570100See
CHNChina Yunnan Province Naxi pop 20.057096See
CHNChina Yunnan Province Puyi0.053076See
KORSouth Korea pop 210.60.0530207See
KORSouth Korea pop 10.0520324See
CHNChina Yunnan Province Bai0.0510128See
CHNChina Jiangxi Province0.051098See
CHNChina Shandong Province Han0.051098See
CHNChina Inner Mongolia Autonomous Region Northeast9.70.0510496See
SGPSingapore SGVP Malay MAS0.045089See
KORSouth Korea pop 110.0440149See
CHNChina Yunnan Province Blang0.043094See
CHNChina Harbin Manchu pop 20.042050See
CHNChina Urumqi Han0.042059See
JPNJapan pop 20.0420916See
CHNChina Yunnan Province Nu0.0410107See
JPNJapan pop 170.03913078See
ESPSpain Andalusia0.037099See
CHNChina Wanwei, Wutou and Shanxin Islands Jing0.0360138See
JPNJapan Fukuoka0.035086See
JPNJapan Central0.0340371See
JPNJapan pop 76.00.0304317See
TWNTaiwan Ami pop 20.030050See
SGPSingapore Riau Malay0.0290132See
USAUSA Mexican American Mestizo pop 20.0270113See
JPNJapan pop 45.30.0270525See
CHNChina Urumqi Kazak0.024042See
ESPSpain Catalonia Girona0.024088See
CHNChina Yunnan Province Lahu0.021070See
JPNJapan South4.00.0202125See
TWNTaiwan Han0.020050See
CHNChina Yunnan Province Lisu0.0190111See
USAUSA Philippines0.0170105See
JPNJapan pop 90.0150132See
DEUGermany Essen2.90.0140174See
USAUSA San Diego2.40.0121496See
MNGMongolia Ulaanbaatar Khalkha0.012041See
FRAFrance Ceph0.0120124See
FRAFrance Rennes0.0120200See
FRAFrance Lille0.011095See
ITAItaly Turin0.011087See
PNGPapua New Guinea East New Britain Tolai0.011048See
RUSRussia Northwest Slavic0.0100200See
TWNTaiwan Bunun pop 20.010050See
ITAItaly North pop 32.00.010097See
CZECzech Republic0.0100106See
ARGArgentina Buenos Aires1.80.0090466See
CMRCameroon Saa0.0090172See
CHNChina Urumqi Uyghur1.80.009057See
RUSRussia Tuva pop 20.0090169See
SWESweden pop 20.0080200See
FRAFrance Southeast1.50.0080130See
FRAFrance Rennes pop 21.40.0070148See
USAUSA Minnesota Olmsted0.0070339See
USAUSA Caucasian pop 50.0070268See
ENGEngland Northwest Mixed0.00602960See
IRLIreland South1.20.0060250See
FRAFrance West Breton0.0060150See
GBRUnited Kingdom1.00.0050187See
DEUGermany pop 20.0050206See
GRCGreece pop 40.005098See
CZECzech Republic pop 21.00.005099See
NZLNew Zealand Maori0.0050200See
RUSRussian Federation Vologda Region0.80.0042119See
ARGArgentina Gran Chaco Eastern Toba0.0040135See
NICNicaragua Managua0.70.0036339See
DEUGermany DKMS - German donors0.00353456066See
RUSRussia Belgorod region0.70.0033153See
SWESweden pop 30.0030175See
ITAItaly Sardinia pop20.50.00301129See
AUTAustria pop 20.0030490See
ZAFSouth Africa Worcester1.00.0030159See
ZWEZimbabwe Harare Shona0.0020230See
ITAItaly Central0.0020380See
AREUnited Arab Emirates Pop 10.0010570See
LKASri Lanka Colombo0.10.0010714See
RUSRussia Karelia0.00051075See
SDNSudan Central Region0.00.000097See
PNGPapua New Guinea Highland pop20.000028See
NZLNew Zealand Maori pop 20.00.000055See
PNGPapua New Guinea Lowland Roro0.000026See
PNGPapua New Guinea Trobriand Island0.000081See
PNGPapua New Guinea Lowland0.000047See
PNGPapua New Guinea Highland0.000094See
MNGMongolia Tarialan Khoton0.000085See
NIUNiue pop 20.00.000038See
TWNTaiwan Aborigine pop 20.000048See
TWNTaiwan Atayal pop 20.000050See
TWNTaiwan Saisiat pop 20.000050See
SGPSingapore SGVP. Indian INS0.000086See
UGAUganda Baganda0.000047See
WSMSamoa West0.000022See
WSMSamoa pop 30.00.000065See
TWNTaiwan Tsou pop 20.000050See
TWNTaiwan Paiwan pop 20.000050See
TWNTaiwan Rukai pop 20.000050See
TWNTaiwan Orchid Island Yami0.000050See
TWNTaiwan Puyuma pop 20.000050See
TONTonga pop 20.00.000050See
BORBorneo Bandjarmasin0.000021See
BRABrazil Central Plateau Xavante0.000074See
ARGArgentina Gran Chaco Mataco Wichi0.000049See
ARGArgentina Gran Chaco Western Toba Pilaga0.000019See
CZECzech Republic Romani0.00.000034See
CHNChina Yunnan Province Pumi0.000063See
ITAItaly Rome0.00.0000100See
ITAItaly Bergamo0.00.0000101See
IDNIndonesia Nusa Tenggara Islands0.000049See
IDNIndonesia Moluccan Islands0.000024See
INDIndia Bombay0.000059See
INDIndia Delhi0.00.0000112See
ECUEcuador African0.000058See
ENGEngland pop 30.00.000061See
GMBGambia pop 20.0000100See

Frequency data at lower resolution for this allele can be found in links below

Allele  Number of Populations 


* Allele Frequency: Total number of copies of the allele in the population sample (Alleles / 2n) in decimal format.
   Important: This field has been expanded to four decimals to better represent frequencies of large datasets (e.g. where sample size > 1000 individuals)
* Phenotype Frequency: Percentage of individuals who have the allele or gene (Individuals / n).
* Allele Frequencies shown in green were calculated from Phenotype Frequencies assuming Hardy-Weinberg proportions.

¹ IMGT/HLA Database - For more details of the allele.
² Distribution - Graphical distribution of the allele.
³ Haplotype Association - Find HLA haplotypes with this allele.
ª Notes - See notes for ambiguous combinations of alleles.

Allele frequency net database (AFND) 2020 update: gold-standard data classification, open access genotype data and new query tools
Gonzalez-Galarza FF, McCabe A, Santos EJ, Jones J, Takeshita LY, Ortega-Rivera ND, Del Cid-Pavon GM, Ramsbottom K, Ghattaoraya GS, Alfirevic A, Middleton D and Jones AR Nucleic Acid Research 2020, 48:D783-8.
Liverpool, U.K.

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