Allele Frequencies in World Populations

HLA Database Allele Report

The list below shows all populations in AFND that contains the allele. If an allele has an entry with a lower resolution this will be shown at the end.



Allele reported 226 time(s) and present in 208 population(s).

Population Phenotype
Frequency (%)
Distribution² Haplotype³
MEXMexico Oaxaca Mixe0.907055See
COLColombia Amazon Region Vaupes0.891046See
VENVenezuela Peraya Yucpa0.885026See
VENVenezuela Orinoco Delta Warao0.853034See
VENVenezuela Marewa Yucpa0.845029See
MEXMexico Tixcacaltuyub Maya0.820967See
COLColombia North Eastern Plains Sikuani0.815027See
MEXMexico Chichen Itza Maya (prehispanic)0.808547See
COLColombia East Amazon Region Nukak0.800020See
BRABrazil Central Plateau Xavante0.799074See
VENVenezuela Sierra de Perija Yucpa0.786073See
MEXMexico Chiapas Lacandon Mayans0.7775218See
MEXMexico Oaxaca Mixtec0.7570103See
MEXMexico Mayan0.733016See
CRICosta Rica and Panama Mestizo0.720056See
MEXMexico Oaxaca Zapotec0.711090See
ARGArgentina Chaco Region El Sauzalito Mataco0.700060See
CAFCentral African Republic Aka Pygmy0.695093See
VENVenezuela Aroy Yucpa0.676017See
MEXMexico Chihuahua Tarahumara0.636044See
ARGArgentina Gran Chaco Mataco Wichi0.622049See
USAUSA New Mexico Zuni0.620051See
ARGArgentina Salta Wichi pop 288.90.611019See
ARGArgentina Gran Chaco Eastern Toba0.6000135See
COLColombia Sierra Nevada de Santa Marta Ijka0.575040See
COLColombia Pacific Coast Region Embera0.571049See
COLColombia Sierra Nevada de Santa Marta Ijka pop 20.567030See
COLColombia West Waunana0.550030See
ARGArgentina Chiriguano77.60.541054See
COLColombia Northwest Tule0.534029See
USAUSA Arizona Pima pop20.529018See
USAUSA Arizona Pima0.5000100See
VENVenezuela Campo Rosario Bari0.500026See
COLColombia Amazon Region Coreguaje pop 20.478045See
USAUSA New Mexico Canoncito Navajo0.475042See
BRABrazil Terena65.00.450060See
BRABrazil Ticuna0.429050See
ECUEcuador Cayapa0.4230183See
COLColombia Guajira Desert Wayuu0.407054See
USAUSA Mexican American Mestizo pop 20.3980113See
NICNicaragua Managua58.00.3887339See
COLColombia Sierra Nevada de Santa Marta Kogi pop 20.360050See
ARGArgentina Gran Chaco Western Toba Pilaga0.358019See
COLColombia Amazon Region Coreguaje0.317030See
COLColombia West Embera0.300020See
ARGArgentina Mapuche0.292048See
GABGabon Haut-Ogooue Dienga0.2900167See
UGAUganda Baganda0.277047See
COLColombia Northwest Choco0.275020See
COLColombia Sierra Nevada de Santa Marta Kogi pop 30.274031See
LBNLebanon Niha el Shouff0.273061See
GABGabon Lambarene0.2710120See
VENVenezuela Saimadoyi Bari0.271035See
KENKenya, Nyanza Province, Luo tribe48.00.2700100See
COLColombia Sierra Nevada de Santa Marta Arsario pop 20.270050See
ITAItaly Sardinia pop 40.265349See
LBNLebanon Kafar Zubian0.262094See
USAUSA South Dakota Sioux0.2550101See
CMRCameroon Saa0.2330172See
MNGMongolia Tarialan Khoton0.221085See
CZECzech Republic pop 238.40.215199See
CHNChina Inner Mongolia Region Ewenki0.213094See
CHNChina Yunnan Province Lisu0.2070111See
COLColombia Providencia Island African0.203030See
CODCongo Kinshasa Bantu0.199090See
GRCGreece pop 40.199098See
CHNChina Urumqi Kazak0.190042See
GRCGreece pop 60.1818242See
GRCGreece pop332.90.1808246See
CZECzech Republic0.1780106See
ZWEZimbabwe Harare Shona0.1780230See
COLColombia West Cauca0.175020See
MNGMongolia Ulaanbaatar Khalkha0.171041See
JPNJapan pop 90.1700132See
ITAItaly Central0.1680380See
CHNChina Yunnan Province Pumi0.167063See
FRAFrance Lille0.163095See
CHNChina Yunnan Province Nu0.1620107See
ITAItaly Rome28.00.1600100See
RUSRussia Northwest Slavic0.1600200See
FRAFrance Rennes pop 229.10.1579148See
CHNChina Pumi0.157051See
RUSRussia Tuva pop 20.1570169See
ECUEcuador African0.155058See
ITAItaly Bergamo29.70.1540101See
RUSRussia Karelia0.15391075See
ESPSpain Catalonia Girona0.147088See
CHNChina Lijiang Naxi0.1460100See
CHNChina Yunnan Province Naxi pop 20.146096See
SWESweden pop 20.1450200See
USAUSA Hawaii0.145039See
ESPSpain Andalusia Romani0.144099See
SAUSaudi Arabia pop 30.140050See
ZAFSouth Africa Worcester26.00.1390159See
GRCGreece pop 826.50.138683See
DEUGermany pop 20.1380206See
ARGArgentina Buenos Aires22.10.1320466See
FRAFrance West Breton0.1300150See
FRAFrance Ceph0.1300124See
FRAFrance Southeast23.80.1270130See
JPNJapan Central0.1230371See
NGANigeria Southwest Abanla Yoruba0.1230130See
DEUGermany DKMS - German donors0.12273456066See
USAUSA Minnesota Olmsted0.1220339See
RUSRussian Federation Vologda Region24.40.1218119See
USAUSA Caucasian pop 50.1210268See
ITAItaly Turin0.121087See
USAUSA San Diego22.40.1192496See
ENGEngland pop 50.119042See
SDNSudan Mixed22.00.1180200See
AUTAustria pop 20.1170490See
IRLIreland South22.00.1160250See
GMBGambia pop 20.1150100See
LBNLebanon Yuhmur0.115082See
CHNChina Harbin Manchu pop 20.115050See
INDIndia Delhi21.60.1145112See
USAUSA African American pop 70.1110193See
ITAItaly North pop 322.00.110097See
SWESweden pop 30.1090175See
CZECzech Republic Romani20.60.108934See
FRAFrance Rennes0.1080200See
CHNChina Yunnan Province Hani0.106047See
ENGEngland pop 321.00.105061See
USAUSA San Francisco Caucasian0.1050220See
DEUGermany Essen18.40.1010174See
ENGEngland Northwest Mixed0.10002960See
SDNSudan Central Region18.60.100097See
JPNJapan pop 170.09833078See
JPNJapan South18.40.0966125See
NIRIreland Northern pop 318.70.0960150See
LBRLiberia Bong County0.0950110See
KORSouth Korea pop 217.90.0940207See
GEOGeorgia Svaneti Region Svan0.094080See
JPNJapan Hyogo16.70.093032See
RUSRussia Belgorod region18.30.0915153See
JPNJapan pop 717.00.0889317See
CHNChina Urumqi Uyghur17.50.088057See
JPNJapan pop 416.40.0860525See
INDIndia Bombay0.085059See
AREUnited Arab Emirates Pop 10.0770570See
IDNIndonesia Nusa Tenggara Islands0.076049See
JPNJapan Fukuoka0.076086See
KORSouth Korea pop 110.0740149See
JPNJapan pop 20.0730916See
THAThailand Bangkok0.0720104See
CHNChina Shandong Province Han0.071098See
CHNChina Jiangxi Province0.071098See
CHNChina Yunnan Province Nu pop 20.069072See
KORSouth Korea pop 10.0690324See
GBRUnited Kingdom13.30.0690187See
ESPSpain Andalusia0.069099See
NZLNew Zealand Maori pop 211.40.068055See
NIUNiue pop 212.50.063038See
CHNChina Urumqi Han0.059059See
NZLNew Zealand Maori0.0550200See
CHNChina Beijing Han0.0530180See
ESPSpain Gipuzkoa Basque0.0510100See
LKASri Lanka Colombo9.10.0480714See
CHNChina Yunnan Province Dai0.047074See
BORBorneo Bandjarmasin0.047021See
INDIndia Lucknow8.50.0460123See
IDNIndonesia Java0.043058See
CHNChina Yunnan Province Blang0.043094See
THAThailand Kamphaeng Phet0.041097See
CHNChina Zhejiang Han pop 20.0402833See
TZATanzania Maasai7.30.0363336See
CHNChina Yunnan Province Lahu0.036070See
CHNChina Guizhou Province Miao0.036085See
GMBGambia pop 36.70.0350939See
WSMSamoa pop 34.40.034065See
IDNIndonesia Moluccan Islands0.033024See
THAThailand Northeast0.030066See
THAThailand East Chanthaburi Khmer0.030083See
TWNTaiwan Han0.030050See
SGPSingapore Riau Malay0.0290132See
SAUSaudi Arabia5.60.028418See
CHNChina Canton Han0.0270264See
THAThailand North Dai Lue0.026096See
CHNChina Shanghai pop 20.025040See
HKGHong Kong Chinese HKBMDR. DQ and DP4.20.02111064See
PNGPapua New Guinea Lowland Roro0.021026See
WSMSamoa pop20.020050See
COKCook Islands0.020050See
ESPSpain Navarre Basques0.0160116See
TWNTaiwan Han Chinese0.0160504See
CHNChina Yunnan Province Bai0.0120128See
CHNChina Wanwei, Wutou and Shanxin Islands Jing0.0110138See
ITAItaly Sardinia pop22.00.01001129See
TWNTaiwan Puyuma pop 20.010050See
TONTonga pop 20.00.000050See
TWNTaiwan Aborigine pop 20.000048See
TWNTaiwan Atayal pop 20.000050See
TWNTaiwan Saisiat pop 20.000050See
TWNTaiwan Bunun pop 20.000050See
TWNTaiwan Tsou pop 20.000050See
TWNTaiwan Paiwan pop 20.000050See
TWNTaiwan Rukai pop 20.000050See
TWNTaiwan Orchid Island Yami0.000050See
TWNTaiwan Ami pop 20.000050See
WSMSamoa West0.000022See
PNGPapua New Guinea Trobriand Island0.000081See
PNGPapua New Guinea Lowland0.000047See
PNGPapua New Guinea Highland0.000094See
PNGPapua New Guinea Highland pop20.000028See
PNGPapua New Guinea East New Britain Tolai0.000048See
CHNChina Yunnan Province Puyi0.000076See
CHNChina Yunnan Province Yao0.000066See

Frequency data at lower resolution for this allele can be found in links below

Allele  Number of Populations 


* Allele Frequency: Total number of copies of the allele in the population sample (Alleles / 2n) in decimal format.
   Important: This field has been expanded to four decimals to better represent frequencies of large datasets (e.g. where sample size > 1000 individuals)
* Phenotype Frequency: Percentage of individuals who have the allele or gene (Individuals / n).
* Allele Frequencies shown in green were calculated from Phenotype Frequencies assuming Hardy-Weinberg proportions.

¹ IMGT/HLA Database - For more details of the allele.
² Distribution - Graphical distribution of the allele.
³ Haplotype Association - Find HLA haplotypes with this allele.
ª Notes - See notes for ambiguous combinations of alleles.

Allele frequency net database (AFND) 2020 update: gold-standard data classification, open access genotype data and new query tools
Gonzalez-Galarza FF, McCabe A, Santos EJ, Jones J, Takeshita LY, Ortega-Rivera ND, Del Cid-Pavon GM, Ramsbottom K, Ghattaoraya GS, Alfirevic A, Middleton D and Jones AR Nucleic Acid Research 2020, 48:D783-8.
Liverpool, U.K.

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