Allele Frequencies in World Populations

HLA Database Allele Report

The list below shows all populations in AFND that contains the allele. If an allele has an entry with a lower resolution this will be shown at the end.



Allele reported 104 time(s) and present in 78 population(s).

Population Phenotype
Frequency (%)
Distribution² Haplotype³
ESPSpain Navarre Basques0.0520116See
ESPSpain Gipuzkoa Basque0.0360100See
SWESweden pop 30.0320175See
FRAFrance Rennes pop 26.10.0309148See
CHNChina Yunnan Province Bai0.0270128See
ESPSpain Catalonia Girona0.024088See
FRAFrance Ceph0.0240124See
ENGEngland pop 50.024042See
ITAItaly Turin0.023087See
USAUSA Minnesota Olmsted0.0220339See
USAUSA Caucasian pop 50.0210268See
ESPSpain Andalusia0.021099See
CZECzech Republic pop 24.00.020299See
ENGEngland Northwest Mixed0.02002960See
ITAItaly North pop 34.00.020097See
SDNSudan Central Region4.10.020097See
ARGArgentina Buenos Aires3.70.0180466See
RUSRussia Belgorod region3.30.0163153See
AUTAustria pop 20.0160490See
FRAFrance Lille0.016095See
ITAItaly Bergamo5.00.0160101See
FRAFrance West Breton0.0160150See
IRLIreland South3.20.0160250See
ITAItaly Rome3.00.0150100See
DEUGermany pop 20.0150206See
RUSRussia Northwest Slavic0.0150200See
GABGabon Lambarene0.0130120See
GBRUnited Kingdom2.60.0130187See
NIRIreland Northern pop 32.70.0130150See
DEUGermany DKMS - German donors0.01283456066See
RUSRussia Karelia0.01211075See
SWESweden pop 20.0120200See
FRAFrance Southeast2.30.0120130See
FRAFrance Rennes0.0120200See
JPNJapan Fukuoka0.012086See
JPNJapan South2.40.0120125See
NZLNew Zealand Maori pop 22.30.011055See
ITAItaly Sardinia pop 40.010249See
CZECzech Republic0.0100106See
CHNChina Harbin Manchu pop 20.010050See
PNGPapua New Guinea Lowland0.010047See
USAUSA Mexican American Mestizo pop 20.0090113See
CHNChina Urumqi Uyghur1.80.009057See
RUSRussian Federation Vologda Region1.70.0084119See
JPNJapan pop 41.50.0080525See
ITAItaly Central0.0080380See
ENGEngland pop 31.60.008061See
MEXMexico Tixcacaltuyub Maya0.007567See
USAUSA San Francisco Caucasian0.0070220See
GRCGreece pop 81.20.006083See
ESPSpain Andalusia Romani0.006099See
JPNJapan pop 170.00523078See
LBRLiberia Bong County0.0050110See
CHNChina Yunnan Province Lisu0.0050111See
CHNChina Inner Mongolia Region Ewenki0.005094See
USAUSA San Diego1.00.0050496See
GRCGreece pop 60.0041242See
GRCGreece pop30.80.0040246See
JPNJapan pop 90.0040132See
NZLNew Zealand Maori0.0030200See
USAUSA African American pop 70.0030193See
KORSouth Korea pop 10.0030324See
DEUGermany Essen0.60.0030174See
AREUnited Arab Emirates Pop 10.0020570See
JPNJapan pop 20.0020916See
NICNicaragua Managua0.40.0018339See
JPNJapan pop 70.30.0015317See
JPNJapan Central0.0010371See
LKASri Lanka Colombo0.10.0010714See
NIUNiue pop 20.00.000038See
KORSouth Korea pop 20.00.0000207See
GRCGreece pop 40.000098See
IDNIndonesia Nusa Tenggara Islands0.000049See
IDNIndonesia Moluccan Islands0.000024See
INDIndia Bombay0.000059See
INDIndia Delhi0.00.0000112See
CHNChina Urumqi Han0.000059See
CHNChina Urumqi Kazak0.000042See
CAFCentral African Republic Aka Pygmy0.000093See
CZECzech Republic Romani0.00.000034See
CHNChina Shanghai pop 20.000040See
CMRCameroon Saa0.0000172See
CODCongo Kinshasa Bantu0.000090See
ECUEcuador African0.000058See
GMBGambia pop 20.0000100See
PNGPapua New Guinea Highland0.000094See
PNGPapua New Guinea Highland pop20.000028See
RUSRussia Tuva pop 20.0000169See
WSMSamoa pop 30.00.000065See
UGAUganda Baganda0.000047See

Frequency data at lower resolution for this allele can be found in links below

Allele  Number of Populations 


* Allele Frequency: Total number of copies of the allele in the population sample (Alleles / 2n) in decimal format.
   Important: This field has been expanded to four decimals to better represent frequencies of large datasets (e.g. where sample size > 1000 individuals)
* Phenotype Frequency: Percentage of individuals who have the allele or gene (Individuals / n).
* Allele Frequencies shown in green were calculated from Phenotype Frequencies assuming Hardy-Weinberg proportions.

¹ IMGT/HLA Database - For more details of the allele.
² Distribution - Graphical distribution of the allele.
³ Haplotype Association - Find HLA haplotypes with this allele.
ª Notes - See notes for ambiguous combinations of alleles.

Allele frequency net database (AFND) 2020 update: gold-standard data classification, open access genotype data and new query tools
Gonzalez-Galarza FF, McCabe A, Santos EJ, Jones J, Takeshita LY, Ortega-Rivera ND, Del Cid-Pavon GM, Ramsbottom K, Ghattaoraya GS, Alfirevic A, Middleton D and Jones AR Nucleic Acid Research 2020, 48:D783-8.
Liverpool, U.K.

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