Allele Frequencies in World Populations

HLA Database » Allele Report

The list below shows all populations in AFND that contains the allele. If an allele has an entry with a lower resolution this will be shown at the end.



Allele reported 221 time(s) and present in 209 population(s).

Population Phenotype
Frequency (%)
Distribution² Haplotype³
SGPSingapore SGVP Malay MAS0.697089See
SGPSingapore SGVP Chinese CHS0.617096See
GABGabon Haut-Ogooue Dienga0.5000167See
PNGPapua New Guinea Eastern Highlands Goroka Asaro0.465057See
CODCongo Kinshasa Bantu63.30.417090See
UGAUganda Baganda0.394047See
PNGPapua New Guinea Madang0.385065See
ECUEcuador African0.379058See
CMRCameroon Saa0.3630172See
PNGPapua New Guinea Highland pop20.359028See
ZWEZimbabwe Harare Shona0.3430230See
ESPSpain Pas Valley0.337088See
KENKenya, Nyanza Province, Luo tribe57.00.3200100See
ESPSpain North Cabuerniga0.316095See
USAUSA African American Bethesda47.70.3070187See
COLColombia Providencia Island African0.300030See
MKDMacedonia pop 50.2960103See
THAThailand North Dai Lue0.292096See
ETHEthiopia Oromo0.289083See
ISRIsrael Ethiopian Jews0.2870122See
AREUnited Arab Emirates Pop 10.2830570See
ETHEthiopia Amhara0.281098See
COLColombia West Cauca0.275020See
ESPSpain North Cantabria0.271083See
HRVCroatia Krk Island Dobrinj0.268028See
GRCGreece pop343.90.2510246See
RUSRussia Tuva Todja0.250022See
ZAFSouth Africa Worcester45.00.2480159See
GRCGreece pop 50.2480500See
NCLNew Caledonia0.246065See
GRCGreece pop242.40.2410120See
SVNSlovenia pop 242.00.2384140See
MARMorocco Atlantic Coast Chaouya0.234098See
MARMorocco Settat Chaouya46.80.234098See
CHNChina Hong Kong and Singapore0.2300135See
USAUSA San Francisco Caucasian0.2300220See
FRAFrance South0.2290350See
DEUGermany Essen42.00.2270174See
SCOScotland Orkney42.30.225099See
RUSRussia Siberia Kushun Buryat0.220025See
FJIFiji Viti Levu Island0.219057See
DEUGermany pop 338.70.2170111See
THAThailand Kamphaeng Phet0.217097See
USAUSA San Diego36.30.2160496See
CHNChina, Xinjiang Uyghur Autonomous Region Han34.30.214370See
FRAFrance Ceph0.2050124See
JPNJapan Nagano36.80.205057See
RUSRussia Arkhangelsk Pomor0.205063See
ISRIsrael Iranian Jews0.2040101See
CZECzech Republic pop 335.60.2030180See
KORSouth Korea pop 10.2020324See
AREUnited Arab Emirates Abu Dhabi0.201952See
CHNChina Canton Han0.2010264See
COLColombia Northwest Choco0.200020See
ECUEcuador African pop20.200045See
CHNChina Urumqi Han0.195059See
POLPoland Lodz0.1940103See
THAThailand pop 20.1940124See
SWESweden Southern Sami0.1940130See
HRVCroatia Krk Island0.1890212See
POLPoland Wielkopolska Region0.188099See
ESPSpain Arratia Valley Basque0.187083See
HKGHong Kong Chinese HKBMDR. DQ and DP33.60.18611064See
RUSRussia Northwest Slavic0.1850200See
ENGEngland pop 635.00.1840177See
HRVCroatia Gorski Kotar Region0.183063See
SGPSingapore SGVP. Indian INS0.182086See
GNQEquatorial Guinea Bioko Island Bubi0.1820100See
JPNJapan Hyogo33.30.181032See
CHNChina pop133.00.1810103See
RUSRussia South Ural Tatar33.30.1810135See
RUSRussia Tuva pop 20.1800169See
KORSouth Korea pop 432.70.1796211See
ENGEngland pop 335.60.178061See
KORSouth Korea pop 230.90.1760207See
RUSRussia South Ural Russian32.40.1760207See
HRVCroatia Krk Island Dubasnica0.174023See
ESPSpain Navarre Basques0.1740116See
CZECzech Republic0.1710106See
JPNJapan Hokkaido Wajin31.00.169371See
FRAFrance Lille0.168095See
PNGPapua New Guinea East New Britain Rabaul0.167060See
JPNJapan pop 1130.60.166962See
CZECzech Republic pop 230.30.165199See
TURTurkey pop 10.1640250See
RUSRussia Siberia Irkutsk Tofalar0.163043See
ARGArgentina Buenos Aires30.70.1610466See
BRABrazil North East Mixed0.1610205See
ITAItaly pop 30.1600179See
CHNChina Zhejiang Han pop 20.1596833See
BRABrazil Paraná Caucasian28.20.1568641See
INDIndia Northeast Vaish0.1560198See
INDIndia Northeast Lachung0.155058See
ITAItaly North pop 328.80.155097See
ESPSpain Valencia28.40.1538577See
INDIndia Uttar Pradesh0.1530202See
CHNChina Harbin Manchu pop 20.149050See
USAUSA Caucasian Bethesda26.30.1490307See
MARMorocco Souss Region0.148098See
CHNChina, Xinjiang Uyghur Autonomous Region Uyghur25.40.147971See
ESPSpain Las Alpujarras0.147185See
AUSAustralia Kimberly Aborigine0.146041See
INDIndia North pop 20.146072See
ITAItaly Rome22.40.1450100See
ESPSpain Catalonia Girona0.145088See
CHNChina, Xinjiang Uyghur Autonomous Region Kazakh23.10.144252See
CHNChina Beijing and Xian0.1430171See
RUSRussia Northwest26.90.14101011See
RUSRussia South Ural Bashkir26.70.1400146See
CHNChina Urumqi Uyghur26.30.140057See
ITAItaly Bergamo27.70.1380101See
ITAItaly Central0.1370380See
BRABrazil Puyanawa26.70.1370150See
INDIndia Northeast Mathur0.1360155See
RUSRussia Tuva pop30.136044See
INDIndia Northeast Mech0.135063See
COLColombia Guajira Peninsula Wayuu0.135088See
JPNJapan pop 170.13413078See
INDIndia Northeast Rajbanshi0.133098See
ESPSpain Gipuzkoa Basque0.1330100See
NICNicaragua Managua24.60.1328339See
LKASri Lanka Colombo24.80.1320714See
GEOGeorgia Svaneti Region Svan0.131080See
IDNIndonesia Java Yogyakarta Region0.130062See
PRTPortugal Center pop 20.1290562See
INDIndia Bombay0.127059See
CZECzech Republic Romani23.50.125334See
CHNChina, Xinjiang Uyghur Autonomous Region Hui20.00.125040See
RUSRussia Siberia Khanty Mansi0.125068See
RUSRussia Murmansk Saomi Mixed0.123070See
CHNChina Yichun0.122076See
JPNJapan pop 20.1210916See
INDIndia Lucknow23.30.1200123See
CHNChina Xinjiang Province Uyghur0.120092See
ESPSpain Murcia0.1200173See
ISRIsrael Arab0.1170109See
JORJordan Amman0.1170146See
JPNJapan Fukuoka0.116086See
USAUSA Hawaii0.115039See
ITAItaly pop 20.113053See
JPNJapan pop 80.1120308See
PRTAzores Terceira Island0.1090130See
PRTPortugal Azores Terceira Island19.30.1053130See
SWESweden Northern Sami0.1040154See
ISRIsrael Moroccan Jews0.1010113See
MEXMexico Nuevo Leon Mestizo20.00.100040See
WSMWestern Samoa and Tokelau0.098051See
INDIndia Northeast Rastogi0.0970196See
ISRIsrael Ashkenazi Jews pop 20.0960132See
AUSAustralia Cape York Peninsula Aborigine0.0960103See
MEXMexico Highlands Mestizos18.10.0940160See
ARGArgentina Gran Chaco Western Toba Pilaga0.093019See
INDIndia Northeast Kayastha0.0920190See
RUSRussia, South Ural, Chelyabinsk region, Nagaybaks17.00.0850112See
RUSRussia Siberia Khabarovsk Evenki0.080025See
INDIndia Northeast Sunni0.0790188See
MEXMexico Guanajuato and Jalisco Mestizo15.80.0790101See
ISRIsrael Non Ashkenazi Jews0.076080See
ISRIsrael Yemenite Jews0.075076See
HRVCroatia Krk Island Vrbnik0.071028See
ISRIsrael Libyan Jews0.0700119See
ISRIsrael Ashkenazi Jews0.069080See
RUSRussia Siberia Ulchi0.068073See
MNGMongolia Tarialan Khoton0.060085See
RUSRussia Siberia Negidal0.057035See
RUSRussia Nenet Mixed0.055055See
COLColombia Sierra Nevada de Santa Marta Ijka pop 20.050030See
COLColombia Sierra Nevada de Santa Marta Arhuaco0.0490107See
CHNChina Urumqi Kazak0.048042See
USAUSA South Dakota Sioux0.0470101See
PERPeru Quechua0.045044See
COKCook Islands Rarotonga0.045078See
MEXMexico Tixcacaltuyub Maya0.044867See
MNGMongolia Ulaanbaatar Khalkha0.041041See
MEXMexico Mayan0.033016See
ECUEcuador Cayapa pop 20.029434See
ARGArgentina Rosario Toba5.80.029086See
MEXMexico Oaxaca Mixtec0.0290103See
INDIndia Northeast Shia0.0290190See
RUSRussia Siberia Lower Yenisey Ket0.029017See
MEXMexico Oaxaca Zapotec0.028090See
MEXMexico Guadalajara Mestizo0.028054See
ARGArgentina Chiriguano5.40.027054See
RUSRussia Siberia Chukchi0.022071See
RUSRussia Siberia Eskimo0.021070See
RUSRussia Siberia Dudinka Nganasan0.021024See
ARGArgentina Gran Chaco Mataco Wichi0.011049See
RUSRussia Siberia North East Kamchatka Koryak0.010092See
MEXMexico Chiapas Lacandon Mayans0.0069218See
ARGArgentina Gran Chaco Eastern Toba0.0040135See
ECUEcuador Cayapa0.0030183See
USAUSA Arizona Gila River Amerindian0.0020492See
RUSRussia Siberia Gvaysugi Udege0.000025See
RUSRussia Siberia Sulamai Ket0.000022See
RUSRussia Siberia Polygus Evenk0.000035See
PRYParaguay Aché0.000087See
RUSRussia Siberia NW of Sakhalin Island Nivkh0.000032See
RUSRussia Siberia Chukotka Peninsula Chukchi0.000059See
RUSRussia Siberia Chukotka Peninsula Eskimo0.000080See
CANCanada British Columbia Athabaskan0.000062See
BRABrazil Guarani Nandeva0.000086See
BRABrazil Kaingang0.0000235See
BRABrazil Guarani M bya0.000093See
BRABrazil Central Plateau Xavante0.000074See

Frequency data at lower resolution for this allele can be found in links below

Allele  Number of Populations 


* Allele Frequency: Total number of copies of the allele in the population sample (Alleles / 2n) in decimal format.
   Important: This field has been expanded to four decimals to better represent frequencies of large datasets (e.g. where sample size > 1000 individuals)
* Phenotype Frequency: Percentage of individuals who have the allele or gene (Individuals / n).
* Allele Frequencies shown in green were calculated from Phenotype Frequencies assuming Hardy-Weinberg proportions.

¹ IMGT/HLA Database - For more details of the allele.
² Distribution - Graphical distribution of the allele.
³ Haplotype Association - Find HLA haplotypes with this allele.
ª Notes - See notes for ambiguous combinations of alleles.


Allele frequency net database (AFND) 2020 update: gold-standard data classification, open access genotype data and new query tools
Gonzalez-Galarza FF, McCabe A, Santos EJ, Jones J, Takeshita LY, Ortega-Rivera ND, Del Cid-Pavon GM, Ramsbottom K, Ghattaoraya GS, Alfirevic A, Middleton D and Jones AR Nucleic Acid Research 2020, 48:D783-8.
Liverpool, U.K.

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