Allele Frequencies in World Populations

HLA Database » Allele Report

The list below shows all populations in AFND that contains the allele. If an allele has an entry with a lower resolution this will be shown at the end.



Allele reported 225 time(s) and present in 214 population(s).

Population Phenotype
Frequency (%)
Distribution² Haplotype³
SGPSingapore SGVP. Indian INS0.432086See
AUSAustralia Cape York Peninsula Aborigine0.3590103See
SGPSingapore SGVP Chinese CHS0.298096See
RUSRussia Siberia Lower Yenisey Ket0.294017See
AUSAustralia Kimberly Aborigine0.280041See
INDIndia Bombay0.271059See
HRVCroatia Krk Island Dubasnica0.239023See
JPNJapan Fukuoka0.233086See
JPNJapan Hokkaido Wajin40.80.230571See
JPNJapan pop 1138.70.217062See
MNGMongolia Ulaanbaatar Khalkha0.207041See
JPNJapan pop 170.19173078See
LKASri Lanka Colombo33.20.1890714See
INDIndia North pop 20.174072See
JPNJapan Nagano31.60.172957See
JPNJapan pop 80.1720308See
JPNJapan pop 20.1690916See
USAUSA Hawaii0.167039See
NLDNetherlands pop 230.30.1651155See
GEOGeorgia Svaneti Region Svan0.163080See
INDIndia Northeast Kayastha0.1600190See
CZECzech Republic Romani29.40.159734See
RUSRussia Siberia Khanty Mansi0.154068See
CHNChina Xinjiang Province Uyghur0.152092See
INDIndia Northeast Mathur0.1520155See
JPNJapan Hyogo30.00.150032See
CHNChina, Xinjiang Uyghur Autonomous Region Hui30.00.150040See
ISRIsrael Moroccan Jews0.1490113See
INDIndia Northeast Rastogi0.1480196See
INDIndia Northeast Shia0.1470190See
IRNIran Yazd Zoroastrian0.146065See
IRNIran Kurd0.1450100See
HRVCroatia Krk Island Dobrinj0.143028See
INDIndia Lucknow27.50.1380123See
INDIndia Uttar Pradesh0.1380202See
IRNIran Azeri0.1350100See
RUSRussia Northwest25.60.13501011See
HRVCroatia Krk Island0.1320212See
RUSRussia Siberia Sulamai Ket0.130022See
ECUEcuador African0.129058See
RUSRussia South Ural Bashkir23.30.1270146See
KORSouth Korea pop 423.70.1265211See
INDIndia Northeast Sunni0.1250188See
CHNChina, Xinjiang Uyghur Autonomous Region Han24.30.121470See
SGPSingapore SGVP Malay MAS0.121089See
CHNChina Beijing and Xian0.1200171See
INDIndia Northeast Mech0.119063See
IRNIran Fars Parsi0.116073See
ISRIsrael Iranian Jews0.1160101See
FJIFiji Viti Levu Island0.114057See
RUSRussia Tuva pop30.114044See
RUSRussia Tuva Todja0.113022See
ITAItaly pop 20.113053See
INDIndia Northeast Vaish0.1110198See
KORSouth Korea pop 10.1110324See
JORJordan Amman0.1100146See
CHNChina Urumqi Han0.110059See
PRTPortugal Azores Terceira Island19.30.1096130See
ESPSpain Murcia0.1070173See
KORSouth Korea pop 50.1060467See
CZECzech Republic0.1050106See
RUSRussia Tuva pop 20.1010169See
RUSRussia South Ural Russian18.80.1010207See
POLPoland Wielkopolska Region0.100099See
PRTPortugal Center pop 20.0990562See
CHNChina Zhejiang Han pop 20.0990833See
CHNChina, Xinjiang Uyghur Autonomous Region Uyghur19.70.098671See
WSMWestern Samoa and Tokelau0.098051See
PRTAzores Terceira Island0.0970130See
PNGPapua New Guinea Eastern Highlands Goroka Asaro0.097057See
CHNChina pop118.40.0970103See
KORSouth Korea pop 218.80.0970207See
ISRIsrael Ashkenazi Jews pop 20.0960132See
RUSRussia South Ural Tatar17.80.0960135See
INDIndia Northeast Lachung0.095058See
ZAFSouth Africa Worcester18.00.0940159See
ISRIsrael Libyan Jews0.0930119See
NCLNew Caledonia0.092065See
RUSRussia Nenet Mixed0.091055See
ISRIsrael Arab0.0910109See
ISRIsrael Yemenite Jews0.090076See
TURTurkey pop 10.0900250See
SWESweden Southern Sami0.0880130See
AREUnited Arab Emirates Abu Dhabi0.086552See
MNGMongolia Tarialan Khoton0.086085See
RUSRussia Northwest Slavic0.0850200See
CHNChina Harbin Manchu pop 20.085050See
CZECzech Republic pop 216.20.084599See
CHNChina Urumqi Kazak0.083042See
ESPSpain Catalonia Girona0.083088See
CZECzech Republic pop 315.60.0810180See
DEUGermany Essen16.10.0810174See
INDIndia Northeast Rajbanshi0.081098See
IRNIran Baloch0.0800100See
GNQEquatorial Guinea Bioko Island Bubi0.0800100See
FRAFrance Lille0.079095See
HRVCroatia Gorski Kotar Region0.079063See
CHNChina Urumqi Uyghur14.00.079057See
ISRIsrael Ashkenazi Jews0.078080See
PNGPapua New Guinea Highland pop20.077028See
CHNChina, Xinjiang Uyghur Autonomous Region Kazakh15.40.076952See
ENGEngland pop 315.30.076061See
RUSRussia, South Ural, Chelyabinsk region, Nagaybaks14.30.0760112See
USAUSA Caucasian Bethesda15.20.0760307See
AREUnited Arab Emirates Pop 10.0750570See
USAUSA San Francisco Caucasian0.0730220See
ARGArgentina Buenos Aires13.90.0720466See
HKGHong Kong Chinese HKBMDR. DQ and DP13.90.07141064See
GRCGreece pop 40.071098See
CHNChina Yichun0.071076See
HRVCroatia Krk Island Vrbnik0.071028See
ESPSpain Gipuzkoa Basque0.0710100See
ESPSpain Navarre Basques0.0710116See
ESPSpain Las Alpujarras0.070485See
RUSRussia Siberia NW of Sakhalin Island Nivkh0.070032See
ITAItaly pop 30.0700179See
ISRIsrael Non Ashkenazi Jews0.069080See
ESPSpain Valencia13.30.0688577See
ITAItaly Central0.0670380See
CHNChina Canton Han0.0660264See
ESPSpain North Cantabria0.066083See
ZWEZimbabwe Harare Shona0.0660230See
GRCGreece pop312.70.0656246See
DEUGermany pop 312.60.0651111See
FRAFrance South0.0640350See
COKCook Islands Rarotonga0.064078See
RUSRussia Arkhangelsk Pomor0.062063See
BRABrazil Paraná Caucasian11.90.0616641See
BRABrazil North East Mixed0.0600205See
RUSRussia Siberia Polygus Evenk0.060035See
ESPSpain Pas Valley0.060088See
USAUSA San Diego11.80.0600496See
CHNChina Hong Kong and Singapore0.0590135See
ITAItaly Bergamo11.90.0590101See
GRCGreece pop 50.0580500See
ENGEngland pop 20.0570114See
BRABrazil Puyanawa11.30.0570150See
ESPSpain North Cabuerniga0.053095See
SWESweden Northern Sami0.0530154See
POLPoland Lodz0.0530103See
UGAUganda Baganda0.053047See
ITAItaly North pop 39.30.053097See
MKDMacedonia pop 50.0530103See
PNGPapua New Guinea East New Britain Rabaul0.050060See
RUSRussia Murmansk Saomi Mixed0.049070See
ESPSpain Arratia Valley Basque0.047083See
GRCGreece pop28.90.0450120See
FRAFrance Ceph0.0440124See
SCOScotland Orkney8.70.043099See
ENGEngland pop 68.50.0420177See
RUSRussia Siberia Dudinka Nganasan0.042024See
CRICosta Rica and Panama Mestizo0.040056See
CODCongo Kinshasa Bantu7.80.039090See
GABGabon Haut-Ogooue Dienga0.0390167See
MEXMexico Guadalajara Mestizo0.037054See
THAThailand pop 20.0360124See
THAThailand Kamphaeng Phet0.036097See
KENKenya, Nyanza Province, Luo tribe7.00.0350100See
NICNicaragua Managua5.90.0332339See
ITAItaly Rome6.60.0330100See
COLColombia Sierra Nevada de Santa Marta Arhuaco0.0330107See
MEXMexico Highlands Mestizos6.30.0310160See
ARGArgentina Gran Chaco Western Toba Pilaga0.030019See
ARGArgentina Mapuche0.029048See
RUSRussia Siberia Negidal0.029035See
IDNIndonesia Java Yogyakarta Region0.026062See
COLColombia West Cauca0.025020See
COLColombia Northwest Choco0.025020See
ETHEthiopia Oromo0.024083See
MARMorocco Settat Chaouya4.80.024098See
MARMorocco Atlantic Coast Chaouya0.024098See
RUSRussia Siberia Irkutsk Tofalar0.023043See
ECUEcuador African pop20.022245See
RUSRussia Siberia Ulchi0.021073See
RUSRussia Siberia Khabarovsk Evenki0.020025See
ETHEthiopia Amhara0.020098See
SVNSlovenia pop 23.60.0181140See
COLColombia Providencia Island African0.017030See
MARMorocco Souss Region0.015098See
PNGPapua New Guinea Madang0.015065See
MEXMexico Nuevo Leon Mestizo2.50.013040See
ARGArgentina Rosario Toba2.30.012086See
CMRCameroon Saa0.0120172See
ARGArgentina Gran Chaco Mataco Wichi0.011049See
BRABrazil Guarani M bya0.011093See
USAUSA African American Bethesda2.20.0110187See
RUSRussia Siberia Chukotka Peninsula Chukchi0.010059See
MEXMexico Guanajuato and Jalisco Mestizo2.00.0100101See
COLColombia Guajira Peninsula Wayuu0.009088See
ARGArgentina Gran Chaco Eastern Toba0.0080135See
ISRIsrael Ethiopian Jews0.0080122See
RUSRussia Siberia Eskimo0.007070See
USAUSA South Dakota Sioux0.0050101See
MEXMexico Chiapas Lacandon Mayans0.0023218See
BRABrazil Kaingang0.0020235See
BRABrazil Guarani Nandeva0.000086See
BRABrazil Central Plateau Xavante0.000074See
CANCanada British Columbia Athabaskan0.000062See
RUSRussia Siberia Chukchi0.000071See
RUSRussia Siberia North East Kamchatka Koryak0.000092See
RUSRussia Siberia Gvaysugi Udege0.000025See
RUSRussia Siberia Chukotka Peninsula Eskimo0.000080See
PRYParaguay Aché0.000087See
PERPeru Quechua0.000044See
RUSRussia Siberia Kushun Buryat0.000025See
THAThailand North Dai Lue0.000096See

Frequency data at lower resolution for this allele can be found in links below

Allele  Number of Populations 


* Allele Frequency: Total number of copies of the allele in the population sample (Alleles / 2n) in decimal format.
   Important: This field has been expanded to four decimals to better represent frequencies of large datasets (e.g. where sample size > 1000 individuals)
* Phenotype Frequency: Percentage of individuals who have the allele or gene (Individuals / n).
* Allele Frequencies shown in green were calculated from Phenotype Frequencies assuming Hardy-Weinberg proportions.

¹ IMGT/HLA Database - For more details of the allele.
² Distribution - Graphical distribution of the allele.
³ Haplotype Association - Find HLA haplotypes with this allele.
ª Notes - See notes for ambiguous combinations of alleles.


Allele frequency net database (AFND) 2020 update: gold-standard data classification, open access genotype data and new query tools
Gonzalez-Galarza FF, McCabe A, Santos EJ, Jones J, Takeshita LY, Ortega-Rivera ND, Del Cid-Pavon GM, Ramsbottom K, Ghattaoraya GS, Alfirevic A, Middleton D and Jones AR Nucleic Acid Research 2020, 48:D783-8.
Liverpool, U.K.

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