Allele Frequencies in World Populations

HLA Database » Allele Report

The list below shows all populations in AFND that contains the allele. If an allele has an entry with a lower resolution this will be shown at the end.



Allele reported 239 time(s) and present in 222 population(s).

Population Phenotype
Frequency (%)
Distribution² Haplotype³
SGPSingapore SGVP. Indian INS0.386086See
ESPSpain Arratia Valley Basque0.313083See
ESPSpain Las Alpujarras0.288385See
INDIndia Northeast Mech0.285063See
INDIndia Northeast Kayastha0.2760190See
JORJordan Amman0.2690146See
ISRIsrael Libyan Jews0.2670119See
INDIndia Northeast Rajbanshi0.265098See
ESPSpain Gipuzkoa Basque0.2600100See
RUSRussia Siberia Kushun Buryat0.260025See
ESPSpain Navarre Basques0.2590116See
CUBCuba Mixed0.250078See
INDIndia Northeast Mathur0.2480155See
INDIndia Northeast Rastogi0.2370196See
INDIndia Northeast Lachung0.224058See
ETHEthiopia Oromo0.223083See
ISRIsrael Yemenite Jews0.221076See
ESPSpain Catalonia Girona0.221088See
RUSRussia South Ural Bashkir40.40.2160146See
CHNChina, Xinjiang Uyghur Autonomous Region Uyghur39.40.211371See
CHNChina Urumqi Uyghur33.30.211057See
LKASri Lanka Colombo36.80.2110714See
INDIndia Northeast Vaish0.2090198See
ESPSpain North Cantabria0.205083See
ETHEthiopia Amhara0.204098See
INDIndia Lucknow39.20.2030123See
CZECzech Republic pop 236.40.202599See
MARMorocco Souss Region0.202098See
COLColombia Northwest Choco0.200020See
ITAItaly pop 20.198053See
RUSRussia South Ural Tatar36.30.1960135See
CHNChina Xinjiang Province Uyghur0.190092See
ISRIsrael Moroccan Jews0.1880113See
INDIndia Northeast Shia0.1870190See
IRNIran Yazd Zoroastrian0.185065See
CHNChina Yichun0.184076See
INDIndia Uttar Pradesh0.1830202See
SGPSingapore SGVP Malay MAS0.182089See
INDIndia Northeast Sunni0.1810188See
ITAItaly pop 30.1800179See
MARMorocco Atlantic Coast Chaouya0.180098See
MARMorocco Settat Chaouya36.00.180098See
PRTAzores Terceira Island0.1790130See
ESPSpain Pas Valley0.179088See
RUSRussia Siberia Khanty Mansi0.176068See
ESPSpain Murcia0.1750173See
CZECzech Republic0.1710106See
ISRIsrael Non Ashkenazi Jews0.169080See
ESPSpain North Cabuerniga0.168095See
ENGEngland pop 20.1670114See
PRTPortugal Azores Terceira Island29.80.1667130See
INDIndia Bombay0.161059See
CZECzech Republic Romani29.40.159734See
PRTPortugal Center pop 20.1580562See
FRAFrance West Breton0.1560150See
ITAItaly North pop 328.90.156097See
ITAItaly Central0.1540380See
ESPSpain Valencia27.60.1491577See
GBRUnited Kingdom pop 20.1450101See
AREUnited Arab Emirates Abu Dhabi0.144252See
FRAFrance Ceph0.1410124See
POLPoland Lodz0.1410103See
ARGArgentina Buenos Aires25.70.1390466See
ENGEngland pop 325.40.136061See
DEUGermany pop 325.20.1351111See
SCOScotland Orkney26.00.134099See
RUSRussia South Ural Russian26.10.1330207See
ENGEngland pop 625.40.1330177See
BRABrazil Paraná Caucasian24.30.1326641See
USAUSA Caucasian Bethesda24.00.1320307See
FRAFrance South0.1290350See
ITAItaly Bergamo24.70.1280101See
ISRIsrael Arab0.1280109See
ISRIsrael Ashkenazi Jews0.127080See
HRVCroatia Gorski Kotar Region0.127063See
FRAFrance Lille0.126095See
GRCGreece Crete0.1260135See
SVNSlovenia pop 223.60.1259140See
ISRIsrael Ashkenazi Jews pop 20.1250132See
CHNChina pop123.30.1240103See
ISRIsrael Ethiopian Jews0.1230122See
DZAAlgeria pop 223.00.1225106See
RUSRussia Northwest23.10.12201011See
USAUSA San Diego21.70.1220496See
BRABrazil North East Mixed0.1200205See
GNQEquatorial Guinea Bioko Island Bubi0.1200100See
CZECzech Republic pop 322.80.1190180See
ITAItaly Rome23.70.1180100See
RUSRussia Nenet Mixed0.118055See
RUSRussia Siberia Lower Yenisey Ket0.118017See
USAUSA San Francisco Caucasian0.1180220See
POLPoland Wielkopolska Region0.117099See
CHNChina Beijing and Xian0.1170171See
IRNIran Fars Parsi0.110073See
IDNIndonesia Java Yogyakarta Region0.110062See
BELBelgium pop 220.70.1090715See
CHNChina Urumqi Kazak0.107042See
UGAUganda Baganda0.106047See
CHNChina, Xinjiang Uyghur Autonomous Region Kazakh19.20.105852See
CHLChile Santiago pop 20.1050124See
AREUnited Arab Emirates Pop 10.1050570See
RUSRussia Northwest Slavic0.1050200See
RUSRussia Siberia Dudinka Nganasan0.104024See
ECUEcuador African0.103058See
CHNChina Urumqi Han0.102059See
MEXMexico Guadalajara Mestizo0.102054See
RUSRussia Tuva0.0990190See
BRABrazil Puyanawa18.00.0970150See
CHNChina Harbin Manchu pop 20.096050See
GEOGeorgia Svaneti Region Svan0.094080See
ARGArgentina Gran Chaco Western Toba Pilaga0.093019See
DEUGermany Essen16.70.0920174See
MNGMongolia Tarialan Khoton0.092085See
USAUSA African American Bethesda18.20.0910187See
ZAFSouth Africa Worcester18.00.0910159See
RUSRussia Tuva pop 20.0890169See
MEXMexico Nuevo Leon Mestizo17.50.088040See
TURTurkey pop 10.0880250See
ISRIsrael Iranian Jews0.0880101See
CHNChina, Xinjiang Uyghur Autonomous Region Hui17.50.087540See
CHNChina, Xinjiang Uyghur Autonomous Region Han17.10.085770See
SGPSingapore SGVP Chinese CHS0.085096See
IRNIran Kurd0.0800100See
GRCGreece pop 50.0800500See
ECUEcuador African pop20.077845See
THAThailand pop 20.0770124See
NLDNetherlands pop 214.20.0737155See
KORSouth Korea pop 50.0730467See
MEXMexico Highlands Mestizos14.40.0720160See
HRVCroatia Krk Island Dobrinj0.071028See
KORSouth Korea pop 413.70.0710211See
KORSouth Korea pop 213.00.0700207See
KENKenya, Nyanza Province, Luo tribe14.00.0700100See
GRCGreece pop313.50.0699246See
INDIndia North pop 20.069072See
THAThailand Kamphaeng Phet0.067097See
COLColombia Sierra Nevada de Santa Marta Ijka pop 20.067030See
CODCongo Kinshasa Bantu12.20.067090See
GRCGreece pop212.80.0660120See
NICNicaragua Managua12.10.0645339See
USAUSA Hawaii0.064039See
GRCGreece pop 40.061098See
IRNIran Azeri0.0600100See
CRICosta Rica and Panama Mestizo0.060056See
CHNChina Zhejiang Han pop 20.0576833See
CHNChina Canton Han0.0570264See
KORSouth Korea pop 10.0560324See
SWESweden Southern Sami0.0540130See
ARGArgentina Rosario Toba10.50.052086See
GABGabon Haut-Ogooue Dienga0.0510167See
COLColombia West Cauca0.050020See
TURTurkey pop 30.050050See
MEXMexico Guanajuato and Jalisco Mestizo9.90.0500101See
RUSRussia Siberia Eskimo0.050070See
CHNChina Hong Kong and Singapore0.0480135See
RUSRussia Siberia Irkutsk Tofalar0.047043See
USAUSA South Dakota Sioux0.0470101See
RUSRussia Tuva pop30.045044See
PERPeru Quechua0.045044See
HRVCroatia Krk Island Dubasnica0.043023See
HKGHong Kong Chinese HKBMDR. DQ and DP8.20.04231064See
RUSRussia Siberia Ulchi0.041073See
RUSRussia Siberia Khabarovsk Evenki0.040025See
RUSRussia Siberia Sulamai Ket0.040022See
AUSAustralia Cape York Peninsula Aborigine0.0400103See
HRVCroatia Krk Island0.0380212See
RUSRussia Murmansk Saomi Mixed0.037070See
ZWEZimbabwe Harare Shona0.0370230See
HRVCroatia Krk Island Vrbnik0.036028See
IRNIran Baloch0.0350100See
COLColombia Providencia Island African0.033030See
COLColombia Sierra Nevada de Santa Marta Arhuaco0.0330107See
MEXMexico Sonora Seri0.030034See
MKDMacedonia pop 50.0290103See
ARGArgentina Mapuche0.029048See
CMRCameroon Saa0.0290172See
COLColombia Guajira Peninsula Wayuu0.027088See
ARGArgentina Salta Wichi pop 25.30.026019See
RUSRussia Tuva Todja0.023022See
MEXMexico Tixcacaltuyub Maya0.022467See
MEXMexico Oaxaca Zapotec0.022090See
RUSRussia Siberia Chukotka Peninsula Chukchi0.020059See
RUSRussia Siberia Chukotka Peninsula Eskimo0.020080See
WSMWestern Samoa and Tokelau0.020051See
RUSRussia Siberia Gvaysugi Udege0.020025See
RUSRussia Belgorod region3.90.0196153See
ARGArgentina Chiriguano3.60.018054See
BRABrazil Guarani Nandeva0.017086See
COLColombia Northwest Tule0.017029See
CANCanada British Columbia Athabaskan0.016062See
ARGArgentina Gran Chaco Eastern Toba0.0150135See
NCLNew Caledonia0.015065See
RUSRussia Siberia Negidal0.014035See
PNGPapua New Guinea Highland pop20.013028See
MNGMongolia Ulaanbaatar Khalkha0.012041See
ARGArgentina Gran Chaco Mataco Wichi0.011049See
THAThailand North Dai Lue0.010096See
JPNJapan pop 20.0080916See
MEXMexico Mazatecan0.007089See
SWESweden Northern Sami0.0070154See
MEXMexico Chiapas Lacandon Mayans0.0069218See
JPNJapan Fukuoka0.006086See
COKCook Islands Rarotonga0.006078See
BRABrazil Guarani M bya0.005093See
RUSRussian Federation Vologda Region0.80.0042119See
JPNJapan pop 170.00363078See
BRABrazil Kaingang0.0020235See
BRABrazil Central Plateau Xavante0.000074See
JPNJapan pop 80.0000308See
JPNJapan pop 110.00.000062See
FJIFiji Viti Levu Island0.000057See
RUSRussia Siberia NW of Sakhalin Island Nivkh0.000032See
RUSRussia Siberia Polygus Evenk0.000035See
RUSRussia Siberia North East Kamchatka Koryak0.000092See
RUSRussia Siberia Chukchi0.000071See
MEXMexico Oaxaca Mixtec0.0000103See
PRYParaguay Aché0.000087See
PNGPapua New Guinea Eastern Highlands Goroka Asaro0.000057See
PNGPapua New Guinea Madang0.000065See
PNGPapua New Guinea East New Britain Rabaul0.000060See

Frequency data at lower resolution for this allele can be found in links below

Allele  Number of Populations 


* Allele Frequency: Total number of copies of the allele in the population sample (Alleles / 2n) in decimal format.
   Important: This field has been expanded to four decimals to better represent frequencies of large datasets (e.g. where sample size > 1000 individuals)
* Phenotype Frequency: Percentage of individuals who have the allele or gene (Individuals / n).
* Allele Frequencies shown in green were calculated from Phenotype Frequencies assuming Hardy-Weinberg proportions.

¹ IMGT/HLA Database - For more details of the allele.
² Distribution - Graphical distribution of the allele.
³ Haplotype Association - Find HLA haplotypes with this allele.
ª Notes - See notes for ambiguous combinations of alleles.


Allele frequency net database (AFND) 2020 update: gold-standard data classification, open access genotype data and new query tools
Gonzalez-Galarza FF, McCabe A, Santos EJ, Jones J, Takeshita LY, Ortega-Rivera ND, Del Cid-Pavon GM, Ramsbottom K, Ghattaoraya GS, Alfirevic A, Middleton D and Jones AR Nucleic Acid Research 2020, 48:D783-8.
Liverpool, U.K.

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