Allele Frequencies in World Populations

HLA Database » Allele Report

The list below shows all populations in AFND that contains the allele. If an allele has an entry with a lower resolution this will be shown at the end.



Allele reported 193 time(s) and present in 190 population(s).

Population Phenotype
Frequency (%)
Distribution² Haplotype³
MEXMexico Jalisco, Tlaquepaque0.282139See
MEXMexico San Luis Potosi Rural0.270187See
MEXMexico Mexico City South0.259652See
MEXMexico Mexico City West0.250033See
MEXMexico Hidalgo Rural0.240781See
MEXMexico Tlaxcala, Tlaxcala city0.2320181See
MEXMexico Tlaxcala Rural0.2265830See
VENVenezuela Zulia Maracaibo Mixed0.225020See
NORNorway Sami0.2250200See
MEXMexico Quintana Roo, Cancun0.218848See
MEXMexico Mexico City North0.2138751See
MEXMexico Puebla Rural0.2104833See
BRABrazil Guarani Nandeva0.209086See
MEXMexico Puebla Mestizo0.202099See
MEXMexico Mexico City East0.200079See
MEXMexico Puebla, Puebla city0.19441994See
MEXMexico Coahuila Rural0.1927216See
MEXMexico Nuevo Leon, Monterrey city0.1903226See
MEXMexico Baja California Rural0.190050See
MEXMexico Nuevo Leon Rural0.1886439See
MEXMexico Morelos, Cuernavaca0.182982See
MEXMexico Oaxaca Rural0.1786485See
MEXMexico Tamaulipas Rural0.1746125See
MEXMexico Tamaulipas, Ciudad Victoria0.173923See
MEXMexico Michoacan Rural0.1719348See
MEXMexico Sonora, Hermosillo0.171799See
MEXMexico Aguascalientes state0.168495See
MEXMexico Guanajuato, Leon0.166778See
MEXMexico Veracruz, Poza Rica0.166745See
MEXMexico Oaxaca, Oaxaca city0.1656151See
MEXMexico Coahuila, Saltillo0.164472See
MEXMexico Veracruz, Xalapa0.1631187See
MEXMexico Guanajuato Rural0.1626162See
MEXMexico Zacatecas, Zacatecas city0.160784See
MEXMexico Hidalgo, Pachuca0.158541See
MEXMexico Chihuahua, Ciudad Juarez0.1574106See
MEXMexico Zacatecas, Fresnillo0.1571103See
MEXMexico Coahuila, Torreon0.1563396See
MEXMexico Veracruz Rural0.1562539See
MEXMexico Mexico City Center0.1558152See
MEXMexico Veracruz, Veracruz city0.1541171See
PNGPapua New Guinea Highland0.154094See
MEXMexico Veracruz, Cordoba0.151856See
MEXMexico Zacatecas Rural0.1506266See
MEXMexico Quintana Roo Rural0.150050See
MEXMexico Durango, Durango city0.1419153See
MEXMexico Veracruz, Orizaba0.141760See
MEXMexico Jalisco, Guadalajara city0.13821189See
MEXMexico Guanajuato, Guanajuato city0.136422See
MEXMexico Chiapas Rural0.1364121See
MEXMexico Mexico City Metropolitan Area Rural0.1349150See
MEXMexico Sonora Rural0.1345197See
MEXMexico Yucatan Rural0.1343132See
MEXMexico Jalisco Rural0.1340585See
MEXMexico Jalisco, Tlajomulco0.133330See
MEXMexico San Luis Potosi, San Luis Potosi city0.133330See
MEXMexico Michoacan, Morelia0.1325150See
MEXMexico Jalisco, Zapopan0.1310168See
MEXMexico Chihuahua Chihuahua City0.1303119See
MEXMexico Jalisco, Tonala0.128635See
MEXMexico Guerrero state0.1285144See
ECUEcuador Amazonia Mixed Ancestry0.128239See
MEXMexico Queretaro Rural0.127943See
MEXMexico Baja California, La Paz0.120075See
MEXMexico Baja Californa, Mexicali0.1200100See
MEXMexico Baja California, Tijuana0.120025See
MEXMexico Tapachula, Chiapas Mestizo Population20.80.118172See
USAUSA OPTN Hispanic0.11701580See
MEXMexico Nayarit, Tepic0.113497See
RUSRussia Siberia Chukchi0.113071See
MEXMexico Tabasco Rural0.1127142See
MEXMexico Mexico City Mestizo0.1120121See
MEXMexico Queretaro, Queretaro city0.111145See
MYSMalaysia Perak Rawa0.110023See
MEXMexico Chihuahua Rural0.1088236See
MEXMexico Yucatan, Merida0.1051192See
MEXMexico Nayarit Rural0.101664See
MEXMexico Morelos Rural0.100030See
RUSRussia Siberia Eskimo0.100070See
MEXMexico Tabasco, Villahermosa0.097682See
ECUEcuador Andes Mixed Ancestry0.0971824See
ECUEcuador Mixed Ancestry0.09681173See
MEXMexico Durango Rural0.0948326See
VENVenezuela Valencia and Maracaibo Caracus Mixed0.094096See
ZAFSouth Africa Limpopo Venda0.0940117See
ECUEcuador Coast Mixed Ancestry0.0924238See
MEXMexico Sonora, Ciudad Obregón0.0909143See
BFABurkina Faso Mossi0.090053See
IRQIraq Arabs17.40.0872149See
RUSRussia Transbaikal Territory Buryats17.00.0870150See
TZATanzania Dodoma Kongwa0.0830212See
GTMGuatemala, Guatemala City Mixed Ancestry15.80.0827127See
CUBCuba Mixed0.080078See
COLColombia Antioquia Paisa0.0790100See
MEXMexico Sinaloa, Culiacán0.0777103See
BRABrazil North East Mixed0.0770205See
USAUSA OPTN Asian0.0750261See
VENVenezuela Zulia San Jose de Heras Mixed0.075020See
MEXMexico Campeche Rural0.074547See
MEXMexico Veracruz, Coatzacoalcos0.071455See
USAUSA OPTN African American0.07001510See
MEXMexico Sinaloa Rural0.0683183See
CHNChina Shandong Province Linqu County12.20.0629139See
TTOTrinidad African0.060067See
BFABurkina Faso Rimaibe0.060047See
MEXMexico Colima, Colima city0.057461See
PRTPortugal North pop 20.05701801See
MEXMexico Chiapas, Tuxtla Gutierrez0.056652See
BRABrazil Sao Paulo Mixed10.10.0520239See
SWESweden pop 49.80.0502966See
PAKPakistan Burusho0.048092See
NORNorway pop 20.0470576See
MEXMexico Colima Rural0.045543See
MEXMexico Sinaloa Mestizo0.045056See
MEXMexico Campeche, Campeche city0.044134See
NORNorway ethnic Norwegians8.50.04344510See
USAUSA Philippines0.0430105See
ESPSpain Majorca0.0420407See
USAUSA Southeast African American8.00.0400112See
VNMVietnam Hanoi0.040050See
SRBSerbia Vojvodina7.70.0400400See
RUSRussia Northwest pop 38.00.0400100See
ALBAlbania pop 27.00.0375432See
RUSRussia Moscow0.03702650See
MARMorocco pop 20.0370110See
RUSRussia South Ural Russian5.80.0330207See
PNGPapua New Guinea Lowland0.031047See
ESPSpain Valencia6.10.0309577See
FRAFrance West Breton0.0300150See
TURTurkey pop 30.030050See
ESPSpain, Castilla y Leon, Northwest,5.40.02941743See
GBRUnited Kingdom Orkney0.029188See
HRVCroatia pop 20.0290100See
GBRUnited Kingdom East0.0287163See
GBRUnited Kingdom South West0.0281163See
RUSRussia, South Ural, Chelyabinsk region, Nagaybaks5.40.0270112See
USAUSA OPTN Caucasian0.02708525See
GBRUnited Kingdom North0.0261330See
SAUSaudi Arabia pop 20.0260383See
INDIndia Bikaner Non-Raikas5.00.0250127See
RUSRussia South Ural Bashkir4.80.0240146See
ROMRomania pop 34.50.02351469See
IDNIndonesia Nusa Tenggara Islands0.023049See
MMRMyanmar Kayin4.50.022744See
SRBSerbia pop 34.40.02201992See
IDNIndonesia Moluccan Islands0.022024See
ITAItaly pop 44.40.02204575See
MYSMalaysia Perak and Johor Banjar Bugis Jawa0.021094See
SDNSudan Khartoum0.020498See
INDIndia New Delhi pop 20.0200102See
ROMRomania pop 20.02006936See
TURTurkey Ankara0.020050See
PAKPakistan Mixed Sindhi0.0200101See
WALWales pop 24.00.020039979See
IRQIraq Erbil3.70.0190372See
FRAFrance Southeast3.80.0190130See
GBRUnited Kingdom Central0.0188135See
SAUSaudi Arabia pop 43.80.0188499See
ALBAlbanian Kosovo0.0167120See
ESPSpain Majorcans Jews0.0160103See
INDIndia North Gujarat3.00.0152338See
RUSRussia South Ural Tatar3.00.0150135See
ESPSpain Minorca0.015094See
PAKPakistan Brahui0.0150104See
PAKPakistan Mixed Pathan0.0150100See
GBRUnited Kingdom pop 20.0150101See
PAKPakistan Kalash0.014069See
HRVCroatia pop 32.50.0125120See
RUSRussia Northwest pop 22.40.0120346See
RUSRussia Northwest2.40.01201011See
MYSMalaysia pop 20.012062See
RUSRussia North Ossetian2.40.0118127See
PNGPapua New Guinea Lowland Wosera0.011079See
MMRMyanmar Bamar2.20.010946See
LKASri Lanka Colombo Sinhalese0.0100101See
BFABurkina Faso Fulani0.010049See
MYSMalaysia Negeri Sembilan Minangkabau0.010034See
KURIraq Kurdistan Region1.90.0100209See
PAKPakistan Baloch0.009066See
TURTurkey pop 20.0070228See
PAKPakistan Karachi Parsi0.006091See
GRCGreece pop 50.0040500See
INDIndia Bikaner Raikas0.70.0040143See
TTOTrinidad South Asian0.000087See
ESPSpain Ibiza0.000088See
ARGArgentina Salta Wichi pop 20.00.000019See

Frequency data at lower resolution for this allele can be found in links below

Allele  Number of Populations 


* Allele Frequency: Total number of copies of the allele in the population sample (Alleles / 2n) in decimal format.
   Important: This field has been expanded to four decimals to better represent frequencies of large datasets (e.g. where sample size > 1000 individuals)
* Phenotype Frequency: Percentage of individuals who have the allele or gene (Individuals / n).
* Allele Frequencies shown in green were calculated from Phenotype Frequencies assuming Hardy-Weinberg proportions.

¹ IMGT/HLA Database - For more details of the allele.
² Distribution - Graphical distribution of the allele.
³ Haplotype Association - Find HLA haplotypes with this allele.
ª Notes - See notes for ambiguous combinations of alleles.


Allele frequency net database (AFND) 2020 update: gold-standard data classification, open access genotype data and new query tools
Gonzalez-Galarza FF, McCabe A, Santos EJ, Jones J, Takeshita LY, Ortega-Rivera ND, Del Cid-Pavon GM, Ramsbottom K, Ghattaoraya GS, Alfirevic A, Middleton D and Jones AR Nucleic Acid Research 2020, 48:D783-8.
Liverpool, U.K.

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