Allele Frequencies in World Populations

HLA Database » Allele Report

The list below shows all populations in AFND that contains the allele. If an allele has an entry with a lower resolution this will be shown at the end.



Allele reported 393 time(s) and present in 382 population(s).

Population Phenotype
Frequency (%)
Distribution² Haplotype³
RUSRussia Mari0.2400202See
PAKPakistan Karachi Parsi0.195091See
RUSRussia, South Ural, Chelyabinsk region, Nagaybaks31.30.1790112See
RUSRussia Kostroma Region0.1750126See
POLPoland Lodz0.1700103See
ESPSpain North31.00.1693156See
MEXMexico San Luis Potosi, San Luis Potosi city0.166730See
RUSRussia Northwest pop 330.00.1600100See
MEXMexico Colima Rural0.159143See
RUSRussia South Ural Russian28.50.1570207See
ESPSpain Majorca0.1510407See
PAKPakistan Baloch0.151066See
VENVenezuela Zulia San Jose de Heras Mixed0.150020See
PRTMadeira pop 30.1500538See
RUSRussia Samara Region0.14202500See
PRTPortugal Castelo Branco0.1410327See
CUBCuba Mixed pop 20.1380189See
RUSRussia Murmansk Saomi Mixed0.136070See
PAKPakistan Brahui0.1350104See
PRTPortugal Viana do Castelo0.1340706See
SDNSudan Central Shaigiya Mixed25.00.133936See
RUSRussia Tatars0.1338355See
RUSRussia Arkhangelsk0.131081See
CZECzech Republic Romani pop 223.90.130446See
ESPSpain Minorca0.130094See
BRABrazil Southeast Campinas Mixed24.20.129399See
BLRBelarus Gomel Region0.1290100See
ENGEngland Manchester24.10.12871640See
ENGEngland Sheffield24.00.12824755See
IRLIreland Wexford25.00.1280200See
RUSRussia Northwest pop 224.00.1280346See
PRTPortugal Beja0.1270699See
PRTPortugal Aveiro0.12605933See
PRTPortugal Coimbra0.12605057See
FRAFrance West Breton0.1260150See
ENGEngland Leeds23.60.12595024See
PRTPortugal Setubal0.12505268See
ENGEngland Liverpool23.30.12421343See
RUSRussia Vologda0.1240121See
PRTPortugal Faro0.12401242See
PRTPortugal Evora0.1230737See
PRTPortugal Portalegre0.12301254See
PRTPortugal Santarem0.12303865See
UKRUkraine Lvov0.1230102See
RUSRussia Northwest24.00.12301011See
ITAItaly North Pavia0.123081See
PRTPortugal Lisbon0.122017420See
PRTPortugal Guarda0.1220797See
PRTPortugal Braga0.12101971See
PRTPortugal Center pop 20.1210562See
BRABrazil Parana Oriental24.20.121033See
PRTPortugal North pop 20.12091801See
ENGEngland North West Mixed pop 221.90.1201379See
PRTPortugal Porto0.12007937See
MEXMexico Guadalajara Mestizo0.120054See
PRTPortugal South pop 20.11901021See
CZECzech Republic pop 322.20.1190180See
RUSRussia Moscow Pop 222.40.11852000See
PAKPakistan Burusho0.118092See
ENGEngland Lancaster22.20.1179545See
ESPSpain Madrid22.00.1168504See
GBRUnited Kingdom North0.1162330See
SWESweden pop 50.11601569See
PRTPortugal Bragança0.1160301See
NORNorway pop 20.1160576See
BRABrazil Sao Paulo Mixed22.20.1160239See
ESPSpain Northwest21.70.11511818See
FRAFrance Grenoble22.50.11511000See
PRTPortugal Vila Real0.11501167See
IRLIreland Donegal21.00.1150200See
ARGArgentina La Plata22.00.1150100See
ESPSpain Ibiza0.115088See
SWESweden pop 422.20.1139966See
ENGEngland Newcastle21.40.11342739See
SWESweden Stockholm21.20.11301347See
USAUSA OPTN Caucasian0.11308525See
SRBSerbia Vojvodina21.50.1130400See
FRAFrance Marseille21.90.11251000See
PRTPortugal Leiria0.11201847See
BRABrazil North East Mixed0.1120205See
IRLIreland South pop 20.111217624See
AUSAustralia South and East Caucasian21.00.11111210See
RUSRussia South Ural Tatar20.70.1110135See
POLPoland pop 322.10.11062907See
WALWales pop 220.80.110039979See
RUSRussia Moscow0.11002650See
FRAFrance Southeast20.80.1100130See
MEXMexico Baja Californa, Mexicali0.1100100See
ESPSpain, Castilla y Leon, Northwest,21.90.10951743See
BRABrazil REDOME Santa Catarina0.1091106673See
BRABrazil Rio Grande do Sul Caucasoid0.10904428See
ESPSpain Valencia20.60.1089577See
FRAFrance Grenoble, Nantes and Rennes0.10806094See
PRTPortugal Viseu0.10802915See
MEXMexico Colima, Colima city0.106661See
JPNJapan pop 80.1060308See
GBRUnited Kingdom South West0.1059163See
FRAFrance Rennes pop 420.80.10541000See
GBRUnited Kingdom Central0.1053135See
FRAFrance Lyon20.70.10524813See
BLRBelarus Brest Region0.1050105See
PRTAzores Terceira Island0.1050130See
MEXMexico Jalisco, Zapopan0.1042168See
FRAFrance Bordeaux20.20.1041990See
BRABrazil REDOME Federal District0.104029549See
ARGArgentina Buenos Aires pop 219.70.10401216See
BRABrazil South East Cord Blood0.103311409See
BRABrazil REDOME Rio de Janeiro0.1031139322See
ZAFSouth Africa Limpopo Venda0.1030117See
SRBSerbia pop 319.40.10291992See
NORNorway ethnic Norwegians19.70.10274510See
ESPSpain Malaga19.40.1022160See
BRABrazil REDOME Parana0.1021341639See
BRABrazil REDOME Goias0.101988574See
BRABrazil REDOME Minas Gerais0.1019211275See
BRABrazil REDOME Paraiba0.101343868See
BRABrazil REDOME Rio Grande do Sul0.1011241329See
BRABrazil REDOME Pernambuco0.100592332See
BRABrazil REDOME Sao Paulo0.1005800809See
BRABrazil Rio Grande do Sul Mixed0.1000324See
BRABrazil Sao Paulo Bauru Mixed0.10003542See
HRVCroatia pop 320.00.1000120See
BRABrazil Rio Grande do Norte Mestizo0.100012973See
NORNorway Sami0.1000200See
ITAItaly pop 419.00.10004575See
BLRBelarus Vitebsk Region0.100070See
TURTurkey Ankara0.100050See
MEXMexico Morelos Rural0.100030See
BRABrazil REDOME Rondonia0.099954396See
SVKSlovakia pop 20.09954234See
BRABrazil REDOME Rio Grande do Norte0.099246603See
BRABrazil Parana Caucasian20.00.09902775See
BRABrazil Parana Cafuzo19.70.0990319See
AUTAustria Cord Bloods0.09851368See
INDIndia Bikaner Raikas18.70.0980143See
UKRUkraine Khmelnytskyi0.0980138See
MEXMexico Sinaloa Mestizo0.098056See
BRABrazil REDOME Ceara0.0971101217See
BIHBosnia and Herzegovina0.0970134See
BRABrazil Parana Mixed race19.30.0970186See
BRABrazil REDOME Tocantins0.095820692See
MEXMexico Campeche Rural0.095747See
BRABrazil REDOME Mato Grosso0.095634649See
BRABrazil REDOME Espirito Santo0.095588485See
BRABrazil Minas Gerais State Mixed17.80.09501000See
MEXMexico Mestizo pop 40.0948269See
ARMArmenia Syunik0.0940117See
VENVenezuela Valencia and Maracaibo Caracus Mixed0.094096See
AUSAustralia West Caucasian18.00.0940891See
ITAItaly North pop 218.00.09402054See
BRABrazil REDOME Bahia0.093847399See
BRABrazil REDOME Mato Grosso do Sul0.093495667See
BRABrazil REDOME Alagoas0.092925349See
BRABrazil Curitiba-Parana Mixed0.0928264See
MEXMexico Nayarit, Tepic0.092897See
MEXMexico Sinaloa, Culiacán0.0922103See
ITAItaly North Pavia pop 217.80.09202416See
BRABrazil REDOME Maranhao0.091410180See
BRABrazil REDOME Sergipe0.09147321See
BRABrazil Mato Grosso do Sul0.0910203See
MEXMexico Jalisco, Tlaquepaque0.089739See
BRABrazil REDOME Acre0.0896859See
GBRUnited Kingdom pop 20.0890101See
HRVCroatia pop 20.0880100See
ITAItaly Lombardy15.90.0880674See
BRABrazil Piaui Mixed0.088021943See
BRABrazil South Ribeirao Preto0.0880184See
HRVCroatia Gorski Kotar Region0.087063See
BRABrazil REDOME Piaui0.087046140See
BRABrazil Para State16.30.08695000See
ROMRomania pop 316.30.08631469See
MEXMexico Sonora, Hermosillo0.085999See
FRAFrance South16.40.0856350See
MEXMexico Chiapas, Tuxtla Gutierrez0.084952See
MEXMexico Tapachula, Chiapas Mestizo Population15.30.083372See
BRABrazil REDOME Roraima0.08324140See
BRABrazil REDOME Para0.083172637See
ISRIsrael Jews pop 215.80.083023000See
ARMArmenia living in Iran0.082085See
MEXMexico Zacatecas Rural0.0818266See
MEXMexico Queretaro Rural0.081443See
MEXMexico Mexico City East0.081379See
MEXMexico Puebla Mestizo0.081099See
MEXMexico Sonora, Ciudad Obregón0.0804143See
MEXMexico Baja California, Tijuana0.080025See
ROMRomania pop 20.08006936See
MEXMexico Jalisco, Guadalajara city0.07961189See
MEXMexico Michoacan, Morelia0.0795150See
BRABrazil REDOME Amapa0.079117864See
MEXMexico Michoacan Rural0.0788348See
MEXMexico Sonora Rural0.0787197See
GBRUnited Kingdom East0.0786163See
ARGArgentina Corrientes14.20.0770155See
BRABrazil Rio Grande do Sul Black0.0760248See
USAUSA OPTN African American0.07601510See
USAUSA OPTN Hispanic0.07601580See
INDIndia Tamil Nadu Dravidian0.0760156See
BRABrazil REDOME Amazonas0.075324129See
RUSRussia South Ural Bashkir15.10.0750146See
GTMGuatemala, Guatemala City Mixed Ancestry14.20.0748127See
MEXMexico San Luis Potosi Rural0.074787See
GRCGreece pop 70.074311250See
ITAItaly Central0.0740380See
ARGArgentina Cuyo Region13.60.0730420See
ITAItaly North Pavia pop 30.0730685See
MKDMacedonia MBMDR - Macedonian13.90.07211283See
MEXMexico Zacatecas, Zacatecas city0.071484See
MEXMexico Sinaloa Rural0.0710183See
BRABrazil Parana Afro Brazilian14.30.071077See
MEXMexico Nayarit Rural0.070364See
BFABurkina Faso Mossi0.070053See
MEXMexico Mexico City Mestizo0.0700121See
BRABrazil Para Cord Blood Unit13.30.0684841See
MEXMexico Guanajuato, Guanajuato city0.068222See
ARMArmenia living in Lebanon0.0680368See
GRCGreece North0.0680500See
BIHBosnia and Herzegovina pop 212.50.0667120See
MEXMexico Veracruz, Poza Rica0.066745See
TZATanzania Dodoma Kongwa0.0660212See
MEXMexico Jalisco Rural0.0657585See
ARMArmenia living in Karabakh0.0650445See
PAKPakistan Mixed Pathan0.0650100See
PERPeru Arequipa Mestizo12.30.0650168See
MEXMexico Mexico City Center0.0649152See
RUSRussia Smolensk0.0640156See
GRCGreece pop 50.0630500See
KORSouth Korea pop 80.06307096See
MEXMexico Zacatecas, Fresnillo0.0619103See
GBRUnited Kingdom Orkney0.061388See
ESPSpain Andalusia Romani0.061099See
MEXMexico Hidalgo, Pachuca0.061041See
MEXMexico Baja California Rural0.060050See
LKASri Lanka Colombo Sinhalese0.0590101See
ARGArgentina Rio Negro Mapuche0.059034See
MEXMexico Coahuila, Torreon0.0588396See
MEXMexico Chihuahua Chihuahua City0.0588119See
MEXMexico Veracruz Rural0.0582539See
ARMArmenia living in USA0.0580233See
PAKPakistan Kalash0.058069See
SDNSudan East Rashaida11.10.057127See
MEXMexico Jalisco, Tonala0.057135See
ESPSpain Majorcans Jews0.0570103See
MEXMexico Durango Rural0.0566326See
MARMorocco pop 20.0560110See
MEXMexico Coahuila Rural0.0550216See
MEXMexico Coahuila, Saltillo0.054872See
ARMArmenia Yerevan0.0540445See
IRNIran pop 40.0539855See
ARMArmenia Shirak0.053076See
MKDMacedonia MBMDR - Macedonian Muslims9.20.052676See
MEXMexico Chihuahua Rural0.0523236See
MEXMexico Guanajuato Rural0.0521162See
MEXMexico Tamaulipas Rural0.0516125See
ITAItaly pop 69.80.0516184See
MEXMexico Guanajuato, Leon0.051378See
ITAItaly Sardinia0.051086See
ALBAlbania pop 210.00.0509432See
CHLChile Huilliche0.050040See
BFABurkina Faso Rimaibe0.050047See
MEXMexico Veracruz, Orizaba0.050060See
MEXMexico Quintana Roo Rural0.050050See
MEXMexico Veracruz, Veracruz city0.0494171See
MEXMexico Nuevo Leon, Monterrey city0.0487226See
MEXMexico Durango, Durango city0.0484153See
ECUEcuador Coast Mixed Ancestry0.0483238See
ECUEcuador Andes Mixed Ancestry0.0479824See
ITAItaly South Campania Region9.30.04761089See
MEXMexico Aguascalientes state0.047495See
RUSRussia North Ossetian8.70.0472127See
TURTurkey Istanbul9.20.0471250See
MKDMacedonia MBMDR - Albanian9.40.0469128See
MEXMexico Baja California, La Paz0.046775See
ECUEcuador Mixed Ancestry0.04601173See
MEXMexico Puebla, Puebla city0.04531994See
ESPSpain Malaga Romani8.80.045080See
USAUSA Southeast African American8.90.0450112See
ARMArmenia Ghegharkunik0.0450242See
MEXMexico Queretaro, Queretaro city0.044445See
MEXMexico Puebla Rural0.0444833See
MEXMexico Mexico City West0.044133See
MEXMexico Hidalgo Rural0.043281See
KURIraq Kurdistan Region8.10.0430209See
GHAGhana Accre Asutuare Akan0.0430429See
MEXMexico Tabasco, Villahermosa0.042782See
CHNChina Shaanxi Province Han0.042010000See
JPNJapan pop 100.0420332See
MEXMexico Chihuahua, Ciudad Juarez0.0417106See
MEXMexico Chiapas Rural0.0413121See
CZECzech Republic Kurd8.10.040574See
INDIndia Andhra Pradesh Sunni2.00.0400100See
MEXMexico mestizo pop 30.0398201See
CHNChina Han7.60.0387314See
MEXMexico Nuevo Leon Rural0.0386439See
MEXMexico Yucatan, Merida0.0385192See
MEXMexico Oaxaca Rural0.0380485See
ITAItaly pop 20.038053See
MEXMexico Yucatan Rural0.0373132See
MEXMexico Mexico City North0.0372751See
IRQIraq Erbil7.30.0363372See
MEXMexico Mexico City Metropolitan Area Rural0.0362150See
TURTurkey pop 20.0360228See
SAUSaudi Arabia pop 46.60.0349499See
MEXMexico Guerrero state0.0347144See
MEXMexico Tlaxcala Rural0.0337830See
MEXMexico Jalisco, Tlajomulco0.033330See
GEOGeorgia Kurds0.033030See
SDNSudan South Nuba6.50.033046See
MEXMexico Veracruz, Xalapa0.0321187See
MEXMexico Quintana Roo, Cancun0.031348See
CHNChina Yunnan Province Han pop 20.0310129See
MEXMexico Morelos, Cuernavaca0.030582See
IRQIraq Arabs6.00.0302149See
INDIndia Bikaner Non-Raikas5.90.0300127See
ITAItaly Sardinia pop26.10.03001129See
TTOTrinidad African0.030067See
SAUSaudi Arabia pop 20.0300383See
INDIndia Tamil Nadu Chennai5.80.0294137See
CHNChina Shandong Province5.70.02907418See
MEXMexico Mexico City South0.028852See
INDIndia North5.30.026885See
VENVenezuela Zulia Maracaibo Mixed0.025020See
PAKPakistan Mixed Sindhi0.0250101See
ALBAlbanian Kosovo0.0250120See
ARMArmenia Lori0.0250102See
MEXMexico Tabasco Rural0.0246142See
COLColombia Bogota and Medellin Mestizo0.023065See
USAUSA OPTN Asian0.0220261See
IRNIran Royan Cord Blood Bank4.40.022015600See
ARGArgentina Chubut Tehuelche0.022023See
CHNChina Shandong Province Linqu County4.30.0217139See
MEXMexico Tamaulipas, Ciudad Victoria0.021723See
TTOTrinidad South Asian0.020087See
INDIndia Andhra Pradesh Brahmin1.00.020098See
INDIndia New Delhi pop 20.0200102See
CHNChina Jiangsu Province0.020020248See
MYSMalaysia Negeri Sembilan Minangkabau0.020034See
INDIndia North pop 30.0200587See
AREUnited Arab Emirates pop 23.80.0190373See
TWNTaiwan Chinese immigrants from Middle China0.0190211See
INDIndia sub-Himalayan West Bengal Kami3.80.0190158See
RUSRussia Nenet Mixed0.018055See
BGDBangladesh Dhaka Bangalee0.0170141See
MEXMexico Oaxaca, Oaxaca city0.0166151See
INDIndia North Gujarat3.30.0165338See
SDNSudan Khartoum0.015398See
RUSRussia Arkhangelsk Pomor0.015063See
CHNChina Shanghai0.014026266See
CHNChina Yunnan Province Naxi0.0130118See
TWNTaiwan Chinese immigrants from North China0.0130152See
ECUEcuador Amazonia Mixed Ancestry0.012839See
THAThailand pop 20.0120124See
MMRMyanmar Kayin2.30.011444See
CHNChina Beijing and Guangzhou0.01001592See
MEXMexico Veracruz, Coatzacoalcos0.008955See
MEXMexico Veracruz, Cordoba0.008956See
BRABrazil Kaingang0.0080235See
MMRMyanmar Mon1.60.007864See
MYSMalaysia pop 30.00701445See
CHNChina Guangdong Province1.20.0060403See
TWNTaiwan Chinese immigrants from South China0.0060172See
MEXMexico Tlaxcala, Tlaxcala city0.0055181See
TWNTaiwan Hakka pop 20.0050714See
THAThailand Kamphaeng Phet0.005097See
THAThailand pop 40.005016807See
TWNTaiwan Minnan pop 20.00307137See
THAThailand Northeast0.002066See
THAThailand Northeast pop 20.0010400See
MYSMalaysia Perak Rawa0.000023See
VNMVietnam Hanoi0.000050See
MYSMalaysia Perak and Johor Banjar Bugis Jawa0.000094See
TWNTaiwan Aborigine0.0000111See
ARGArgentina Kolla0.000061See
BRABrazil Guarani M bya0.000093See
MEXMexico Huasteca Region Teenek0.000055See
ARGArgentina Salta Wichi pop 20.00.000019See
MYSMalaysia pop 20.000062See
BFABurkina Faso Fulani0.000049See
MEXMexico Campeche, Campeche city0.000034See

Frequency data at lower resolution for this allele can be found in links below

Allele  Number of Populations 


* Allele Frequency: Total number of copies of the allele in the population sample (Alleles / 2n) in decimal format.
   Important: This field has been expanded to four decimals to better represent frequencies of large datasets (e.g. where sample size > 1000 individuals)
* Phenotype Frequency: Percentage of individuals who have the allele or gene (Individuals / n).
* Allele Frequencies shown in green were calculated from Phenotype Frequencies assuming Hardy-Weinberg proportions.

¹ IMGT/HLA Database - For more details of the allele.
² Distribution - Graphical distribution of the allele.
³ Haplotype Association - Find HLA haplotypes with this allele.
ª Notes - See notes for ambiguous combinations of alleles.


Allele frequency net database (AFND) 2020 update: gold-standard data classification, open access genotype data and new query tools
Gonzalez-Galarza FF, McCabe A, Santos EJ, Jones J, Takeshita LY, Ortega-Rivera ND, Del Cid-Pavon GM, Ramsbottom K, Ghattaoraya GS, Alfirevic A, Middleton D and Jones AR Nucleic Acid Research 2020, 48:D783-8.
Liverpool, U.K.

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