Allele Frequencies in World Populations

HLA Database » Allele Report

The list below shows all populations in AFND that contains the allele. If an allele has an entry with a lower resolution this will be shown at the end.



Allele reported 356 time(s) and present in 241 population(s).

Population Phenotype
Frequency (%)
Distribution² Haplotype³
TUNTunisia Jerba Berber0.046055See
PRTAzores Central Islands0.036059See
IRLIreland South6.80.0340250See
IRNIran Fars Parsi0.034073See
COLColombia Providencia Island African0.033030See
NIRIreland Northern6.30.03301000See
PRTPortugal North0.033046See
PRTPortugal South0.031049See
MEXMexico Mexico City West0.029433See
MEXMexico Guanajuato, Leon0.025678See
ENGEngland pop 65.10.0250177See
MEXMexico Nuevo Leon Mestizo5.00.025040See
JORJordan Amman0.0240146See
ESPSpain Las Alpujarras0.023585See
NICNicaragua Mestizo (G)4.00.0230155See
IRNIran Yazd Zoroastrian0.023065See
ARGArgentina Rosario Toba4.70.023086See
MEXMexico Guanajuato, Guanajuato city0.022722See
MEXMexico Tamaulipas, Ciudad Victoria0.021723See
ZAFSouth Africa Caucasians0.0210102See
COLColombia Wayu from Guajira Peninsula0.020848See
MEXMexico Quintana Roo, Cancun0.020848See
IRNIran Baloch0.0200100See
DZAAlgeria Oran0.0200100See
USAUSA Caucasian pop 40.01921070See
USAUSA Caucasian Houston3.80.0190194See
ENGEngland Bedfordshire3.70.0186354See
ENGEngland North West3.70.0180298See
INDIndia Northeast Shia0.0180190See
MEXMexico Veracruz, Cordoba0.017956See
IRNIran Kurd pop 20.017060See
MEXMexico San Luis Potosi, San Luis Potosi city0.016730See
IRNIran Saqqez-Baneh Kurds0.016760See
ESPSpain Murcia0.0160173See
MEXMexico Aguascalientes state0.015895See
USAUSA Caucasian2.80.014161655See
ESPSpain Valencia2.80.0141577See
ESPSpain Barcelona3.00.0140941See
USAUSA Caucasian Pittsburgh2.80.0140177See
MEXMexico Nuevo Leon Rural0.0136439See
USAUSA San Antonio Caucasian0.0135222See
USAUSA Southern California Mestizo2.70.013573See
MEXMexico Baja California, La Paz0.013375See
USAUSA Hawaii0.013039See
PRTAzores Oriental Islands0.013043See
FRAFrance Rennes0.0130200See
MEXMexico Sonora Rural0.0127197See
ESPSpain (Catalunya, Navarra, Extremadura, Aaragón, Cantabria,2.50.01264335See
USAUSA NMDP European Caucasian0.01231242890See
NICNicaragua Managua2.40.0120339See
ARGArgentina Buenos Aires2.40.0120466See
BRABrazil Guarani Nandeva0.012086See
ESPSpain North Cantabria0.012083See
MEXMexico Veracruz Xalapa2.40.011984See
BRABrazil Paraná Caucasian2.30.0117641See
DEUGermany DKMS - United Kingdom minority0.01151043See
USAUSA San Francisco Caucasian0.0110220See
COLColombia Barranquilla0.0110188See
ESPSpain Granada0.0110280See
ISRIsrael Ashkenazi Jews pop 20.0110132See
CRICosta Rica Central Valley Mestizo (G)2.20.0110221See
DEUGermany DKMS - Spain minority0.01081107See
MEXMexico Campeche Rural0.010647See
MEXMexico Mexico City Mestizo population0.0105143See
MEXMexico Sonora, Ciudad Obregón0.0105143See
MEXMexico Nayarit, Tepic0.010397See
FRAFrance Rennes pop 30.0100200See
CHESwitzerland Sion0.0100832See
USAUSA Minnesota Olmsted0.0100339See
MEXMexico Guanajuato and Jalisco Mestizo2.00.0100101See
POLPoland Wielkopolska Region0.010099See
INDIndia Uttar Pradesh0.0100202See
BRABrazil Southeast Caucasian1.90.0100103See
RUSRussia Northwest Slavic0.0100200See
USAUSA NMDP North American Amerindian0.010035791See
MEXMexico Michoacan, Morelia0.0099150See
MEXMexico Sinaloa, Culiacán0.0097103See
CHESwitzerland Graubunden0.0096759See
MEXMexico Chihuahua, Ciudad Juarez0.0093106See
USAUSA Spain Ancestry0.0090279See
USAUSA NMDP American Indian South or Central America0.00905926See
USAUSA Eastern European0.0090558See
USAUSA Colorado Univ Cord Blood Bank Caucasian0.00903830See
PRTPortugal Azores Terceira Island1.80.0088130See
MEXMexico Jalisco, Guadalajara city0.00881189See
ISRIsrael Morocco Jews0.008436718See
MEXMexico Chihuahua Rural0.0084236See
CHLChile Santiago0.0083920See
COLColombia Bogotá Cord Blood1.60.00821463See
USAUSA Colorado Univ Cord Blood Bank Hispanic0.00801058See
PRTAzores Terceira Island0.0080130See
ESPSpain Ibiza0.008088See
CPVCape Verde Southeastern Islands0.008062See
ARGArgentina Gran Chaco Eastern Toba0.0080135See
NCLNew Caledonia0.008065See
MEXMexico Tamaulipas Rural0.0079125See
USAUSA NMDP Hispanic South or Central American0.0079146714See
NLDNetherlands UMCU1.60.007864See
MEXMexico Durango Rural0.0076326See
USAUSA NMDP Mexican or Chicano0.0076261235See
FRAFrance French Bone Marrow Donor Registry0.007242623See
USAUSA San Diego1.40.0070496See
BRABrazil Puyanawa1.30.0070150See
SWESweden Stockholm1.40.00701347See
ESPSpain Northwest Lugo1.40.0070145See
USAUSA South Dakota Lakota Sioux0.0070302See
ESPSpain Arratia Valley Basque0.007083See
USAUSA Caucasian Bethesda1.40.0070307See
USAUSA African American Bethesda1.40.0070187See
BRABrazil South Caucasian0.006973See
CHESwitzerland Zurich0.00684875See
CHESwitzerland Lugano0.00671169See
MEXMexico Mexico City Center0.0065152See
MEXMexico Durango, Durango city0.0065153See
MEXMexico Mexico City Mestizo pop 20.0064234See
ECUEcuador Coast Mixed Ancestry0.0063238See
MEXMexico Mexico City East0.006379See
DEUGermany DKMS - Portugal minority0.00641176See
MEXMexico Coahuila, Torreon0.0063396See
USAUSA Hispanic pop 20.00631999See
MEXMexico Tabasco, Villahermosa0.006182See
USAUSA Caucasian pop 50.0060268See
LBNLebanon pop 20.0060191See
COKCook Islands Rarotonga0.006078See
CHESwitzerland St Gallen0.00592113See
CHESwitzerland Bern0.00573545See
DEUGermany DKMS - France minority0.00571406See
MEXMexico San Luis Potosi Rural0.005787See
CHESwitzerland Aargau-Solothurn0.00551838See
MEXMexico Mexico City North0.0053751See
CHESwitzerland Basel0.00521888See
USAUSA Italy Ancestry0.0050273See
USAUSA Mexican American Mestizo0.0050553See
NZLNew Zealand Maori with Admixed History1.00.0050105See
IRNIran pop 30.0050100See
AUSAustralia Cape York Peninsula Aborigine0.0050103See
ESPSpain North Cabuerniga0.005095See
ESPSpain Pas Valley0.005088See
CZECzech Republic0.0050106See
ETHEthiopia Amhara0.005098See
ITAItaly Bergamo1.00.0050101See
TUNTunisia pop 30.0050104See
ESPSpain Gipuzkoa Basque0.0050100See
BRABrazil Mixed0.0050108See
ISRIsrael Moroccan Jews0.0050113See
CRICosta Rica African -Caribbean (G)1.00.0050102See
ESPSpain, Canary Islands, Gran canaria island0.50.0047215See
MEXMexico Veracruz Rural0.0046539See
MEXMexico Nuevo Leon, Monterrey city0.0044226See
DEUGermany DKMS - Netherlands minority0.00441374See
ECUEcuador Mixed Ancestry0.00431173See
ECUEcuador Andes Mixed Ancestry0.0042824See
USAUSA NMDP Caribean Hispanic0.0042115374See
IRNIran pop 20.0042120See
NLDNetherlands Leiden0.00401305See
USAUSA NMDP Alaska Native or Aleut0.00401376See
DEUGermany pop 80.004039689See
USAUSA Mexican American Mestizo pop 30.0040116See
USAUSA Philadelphia Caucasian0.70.0040141See
USAUSA Southeast African American0.90.0040112See
BRABrazil North East Mixed0.0040205See
FRAFrance Southeast0.80.0040130See
MEXMexico Yucatan Rural0.0037132See
USAUSA NMDP Middle Eastern or North Coast of Africa0.003770890See
MEXMexico Guerrero state0.0035144See
SVNSlovenia pop 20.70.0035140See
MEXMexico Tabasco Rural0.0035142See
CHESwitzerland Luzern0.00341553See
MEXMexico Oaxaca, Oaxaca city0.0033151See
MEXMexico Mexico City Metropolitan Area Rural0.0033150See
DEUGermany pop 60.00328862See
DEUGermany DKMS - German donors0.00313456066See
MEXMexico Guanajuato Rural0.0031162See
MEXMexico Mexico City Tlalpan0.60.0030330See
USAUSA African American pop 70.0030193See
ITAItaly pop 40.50.00304575See
PRTMadeira pop 20.0030173See
ITAItaly pop 50.0030975See
FINFinland pop20.0030150See
ITAItaly Central0.0030380See
DEUGermany Essen0.60.0030174See
MEXMexico Veracruz, Veracruz city0.0029171See
MEXMexico Michoacan Rural0.0029348See
MEXMexico Veracruz, Xalapa0.0027187See
USAUSA NMDP African American pop 20.0026416581See
RUSRussia Bashkortostan, Tatars0.50.0026192See
MEXMexico Jalisco Rural0.0026585See
DEUGermany DKMS - Bosnia and Herzegovina minority0.00241028See
USAUSA NMDP Hawaiian or other Pacific Islander0.002411499See
MEXMexico Coahuila Rural0.0023216See
USAUSA African American pop 40.00232411See
USAUSA African American pop 30.0020564See
USAUSA Colorado Univ Cord Blood Bank African American0.0020261See
USAUSA NMDP Caribean Indian0.002014339See
BRABrazil Mato Grosso do Sul0.0020203See
SAUSaudi Arabia Guraiat and Hail0.50.0020213See
ISRIsrael Poland Jews0.001913871See
DEUGermany DKMS - Croatia minority0.00192057See
MEXMexico Zacatecas Rural0.0019266See
ISRIsrael Ashkenazi Jews pop 30.00184625See
CZECzech Republic NMDR0.00185099See
DEUGermany DKMS - Austria minority0.00181698See
USAUSA NMDP Caribean Black0.001733328See
POLPoland DKMS0.001820653See
USAUSA NMDP African0.001628557See
CHESwitzerland Lausanne0.0016993See
HRVCroatia pop 40.00164000See
POLPoland BMR0.30.001423595See
RUSRussia Karelia0.00141075See
RUSRussia Nizhny Novgorod, Russians0.30.00131510See
DEUGermany DKMS - Romania minority0.00121234See
ISRIsrael Argentina Jews0.00104307See
ISRIsrael USSR Jews0.001045681See
DEUGermany DKMS - Greece minority0.00111894See
SCOScotland Orkney1.90.001099See
CHNChina Beijing Shijiazhuang Tianjian Han0.0010618See
ISRIsrael USA Jews0.00096058See
MEXMexico Puebla, Puebla city0.00081994See
DEUGermany DKMS - Italy minority0.00091159See
USAUSA NMDP Filipino0.000750614See
ISRIsrael Iraq Jews0.000713270See
USAUSA NMDP Japanese0.000724582See
ISRIsrael Arab pop 20.000612301See
ISRIsrael Tunisia Jews0.00069070See
ISRIsrael Druze0.00055914See
USAUSA NMDP Southeast Asian0.000227978See
USAUSA Asian pop 20.00031772See
USAUSA NMDP Vietnamese0.000243540See
ISRIsrael Kavkazi Jews0.00022840See
HKGHong Kong Chinese BMDR0.00017595See
USAUSA NMDP Korean0.000177584See
USAUSA NMDP Chinese0.000199672See
USAUSA NMDP South Asian Indian0.0000185391See
ECUEcuador Amazonia Mixed Ancestry0.000039See
MEXMexico Tlaxcala, Tlaxcala city0.0000181See
MEXMexico Mexico City South0.000052See
MEXMexico Morelos, Cuernavaca0.000082See
MEXMexico Yucatan, Merida0.0000192See
MEXMexico Campeche, Campeche city0.000034See
MEXMexico Chiapas, Tuxtla Gutierrez0.000052See
MEXMexico Queretaro, Queretaro city0.000045See
MEXMexico Jalisco, Zapopan0.0000168See
MEXMexico Jalisco, Tonala0.000035See
MEXMexico Jalisco, Tlaquepaque0.000039See
MEXMexico Jalisco, Tlajomulco0.000030See
MEXMexico Veracruz, Poza Rica0.000045See
MEXMexico Veracruz, Orizaba0.000060See
MEXMexico Veracruz, Coatzacoalcos0.000055See
MEXMexico Hidalgo, Pachuca0.000041See
CHESwitzerland Geneva pop 20.00001267See
AREUnited Arab Emirates pop 20.00.0000373See
CZECzech Republic pop 20.00.000099See
CZECzech Republic Romani0.00.000034See
INDIndia Northeast Sunni0.0000188See
INDIndia Northeast Lachung0.000058See
INDIndia Northeast Mech0.000063See
INDIndia Northeast Rajbanshi0.000098See
GRCGreece pop 40.000098See
INDIndia Northeast Kayastha0.0000190See
INDIndia Northeast Mathur0.0000155See
INDIndia Northeast Rastogi0.0000196See
INDIndia Northeast Vaish0.0000198See
ESPSpain Catalonia Girona0.000088See
GNBGuinea Bissau0.000065See
CPVCape Verde Northwestern Islands0.000062See
TUNTunisia Matmata Berber0.000081See
TUNTunisia Gabes Arab0.000096See
ISRIsrael Libyan Jews0.0000119See
ISRIsrael Iranian Jews0.0000101See
ISRIsrael Ethiopian Jews0.0000122See
ISRIsrael Yemenite Jews0.000076See
ISRIsrael Arab0.0000109See
CHNChina Urumqi Uyghur0.00.000057See
ARGArgentina Gran Chaco Mataco Wichi0.000049See
ARGArgentina Gran Chaco Western Toba Pilaga0.000019See
MEXMexico Highlands Mestizos0.00.0000160See
IDNIndonesia Nusa Tenggara Islands0.000049See
IDNIndonesia Moluccan Islands0.000024See
IDNIndonesia Singaporean0.000050See
PNGPapua New Guinea Lowland0.000047See
PNGPapua New Guinea Lowland Wosera0.000079See
PNGPapua New Guinea Highland0.000094See
DZAAlgeria pop 20.00.0000106See
BRABrazil Central Plateau Xavante0.000074See
KORSouth Korea pop 30.0000485See
PNGPapua New Guinea Eastern Highlands Goroka Asaro0.000057See
PNGPapua New Guinea Madang0.000065See
PNGPapua New Guinea East New Britain Rabaul0.000060See
PRYParaguay Aché0.000087See
PERPeru Quechua0.000044See
BRABrazil East Amazon0.000041See
CANCanada British Columbia Athabaskan0.000062See
CANCanada British Columbia Penutian0.000026See
PRTPortugal Center0.000050See
ESPSpain Majorca0.0000407See
ESPSpain Minorca0.000094See
USAUSA South Texas Hispanic0.0000194See
KORSouth Korea pop 20.00.0000207See
USAUSA Alaska Yupik0.0000252See
ETHEthiopia Oromo0.000083See
ESPSpain Majorcans Jews0.0000103See
ITAItaly Rome0.00.0000100See
ITAItaly North pop 30.00.000097See
USAUSA Colorado Univ Cord Blood Bank Asian0.0000100See
MKDMacedonia pop 10.0000158See
BRABrazil Kaingang0.0000235See
PAKPakistan Mixed Pathan0.0000100See
PAKPakistan Mixed Sindhi0.0000101See
MARMorocco Nador Metalsa0.000099See
MARMorocco Settat Chaouya0.000098See
FRAFrance West0.00.0000100See
BRABrazil Guarani M bya0.000093See
BRABrazil Southeast Mixed Race0.00.000042See
CAFCentral African Republic Aka Pygmy0.00.000093See
CODCongo Kinshasa Bantu0.00.000090See
WSMWestern Samoa and Tokelau0.000051See
IDNIndonesia Java Yogyakarta Region0.000062See
FJIFiji Viti Levu Island0.000057See
MEXMexico Tlaxcala Rural0.0000830See
MEXMexico Puebla Rural0.0000833See
MEXMexico Oaxaca Rural0.0000485See
MEXMexico Morelos Rural0.000030See
MEXMexico Chiapas Rural0.0000121See
MEXMexico Queretaro Rural0.000043See
MEXMexico Quintana Roo Rural0.000050See
MEXMexico Baja California, Tijuana0.000025See
MEXMexico Nayarit Rural0.000064See
MEXMexico Sinaloa Rural0.0000183See
MEXMexico Baja California Rural0.000050See
MEXMexico Colima Rural0.000043See
MEXMexico Hidalgo Rural0.000081See
MEXMexico Colima, Colima city0.000061See
MEXMexico Zacatecas, Fresnillo0.0000103See
MEXMexico Zacatecas, Zacatecas city0.000084See
MEXMexico Coahuila, Saltillo0.000072See
MEXMexico Baja Californa, Mexicali0.0000100See
MEXMexico Chihuahua Chihuahua City0.0000119See
MEXMexico Sonora, Hermosillo0.000099See

Frequency data at lower resolution for this allele can be found in links below

Allele  Number of Populations 


* Allele Frequency: Total number of copies of the allele in the population sample (Alleles / 2n) in decimal format.
   Important: This field has been expanded to four decimals to better represent frequencies of large datasets (e.g. where sample size > 1000 individuals)
* Phenotype Frequency: Percentage of individuals who have the allele or gene (Individuals / n).
* Allele Frequencies shown in green were calculated from Phenotype Frequencies assuming Hardy-Weinberg proportions.

¹ IMGT/HLA Database - For more details of the allele.
² Distribution - Graphical distribution of the allele.
³ Haplotype Association - Find HLA haplotypes with this allele.
ª Notes - See notes for ambiguous combinations of alleles.


Allele frequency net database (AFND) 2020 update: gold-standard data classification, open access genotype data and new query tools
Gonzalez-Galarza FF, McCabe A, Santos EJ, Jones J, Takeshita LY, Ortega-Rivera ND, Del Cid-Pavon GM, Ramsbottom K, Ghattaoraya GS, Alfirevic A, Middleton D and Jones AR Nucleic Acid Research 2020, 48:D783-8.
Liverpool, U.K.

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