Allele Frequencies in World Populations

HLA Database Allele Report

The list below shows all populations in AFND that contains the allele. If an allele has an entry with a lower resolution this will be shown at the end.



Allele reported 131 time(s) and present in 103 population(s).

Population Phenotype
Frequency (%)
Distribution² Haplotype³
MARMorocco Nador Metalsa0.202099See
ESPSpain, Canary Islands, Gran canaria island29.80.1628215See
NIRIreland Northern29.90.16001000See
ENGEngland North West28.90.1540298See
USAUSA San Francisco Caucasian0.1450220See
SAUSaudi Arabia pop 6 (G)0.133928927See
CHNChina Inner Mongolia Region Ewenki0.133094See
ISRIsrael Ethiopian Jews0.1320122See
USAUSA Caucasian23.40.124761655See
ISRIsrael Yemenite Jews0.120076See
MARMorocco Settat Chaouya0.117098See
MARMorocco Atlantic Coast Chaouya0.116098See
DZAAlgeria Oran0.1160100See
USAUSA Italy Ancestry0.1120273See
POLPoland BMR20.50.108823595See
CPVCape Verde Southeastern Islands0.105062See
BRABrazil Barra Mansa Rio State Caucasian0.1000405See
ISRIsrael Arab0.0960109See
LBNLebanon Kafar Zubian0.091094See
CHNChina Wanwei, Wutou and Shanxin Islands Jing0.0910138See
TWNTaiwan Han0.090050See
BRABrazil Rio de Janeiro Caucasian0.0893521See
CHNChina Han Guandong Province0.0840208See
BRABrazil North East Mixed0.0830205See
ISRIsrael Iranian Jews0.0830101See
BRABrazil Rio de Janeiro Parda0.0828170See
BRABrazil Barra Mansa Rio State Black0.082273See
TWNTaiwan Minnan and Hakka0.0820190See
TWNTaiwan Hakka14.50.082055See
RUSRussia Nizhny Novgorod, Russians15.30.08011510See
THAThailand Bangkok pop 20.080050See
GTMGuatemala Kaqchikel NA-DHS_8 (G)15.80.078919See
ZAFSouth African Black14.90.0775142See
VNMVietnam Kinh15.00.0743101See
INDIndia Mumbai Maratha0.074091See
LBNLebanon Yuhmur0.074082See
USAUSA African American pop 30.0700564See
USAUSA Mexican American Mestizo0.0680553See
HKGHong Kong Chinese HKBMDR HLA 11 loci13.20.06795266See
RUSRussian Federation Vologda Region12.60.0630119See
GNQEquatorial Guinea Bioko Island Bubi0.0630100See
CHNChina Zhejiang Han0.06001734See
SAUSaudi Arabia pop 30.060050See
BRABrazil Rio de Janeiro Black0.058868See
CPVCape Verde Northwestern Islands0.056062See
INDIndia North pop 20.056072See
ISRIsrael Libyan Jews0.0560119See
RUSRussia Belgorod region11.10.0556153See
TWNTaiwan Minnan pop 19.80.0540102See
RUSRussia Tuva pop 20.0530169See
TWNTaiwan Thao10.00.050030See
COLColombia Waunana NA-DHS_20 (G)5.00.050020See
INDIndia Andhra Pradesh Telugu Speaking9.70.0484186See
GNBGuinea Bissau0.046065See
IDNIndonesia Java pop 20.042036See
CANCanada Chipewyan NA-DHS_2 (G)8.00.040025See
TWNTaiwan Siraya7.80.039051See
CHNChina Lijiang Naxi0.0370100See
INDIndia Karnataka Kannada Speaking6.90.0370174See
CHNChina Shandong Province Han0.036098See
CHNChina Guizhou Province Miao0.036085See
CHNChina Jiangxi Province0.036098See
TWNTaiwan Pazeh7.30.036055See
NZLNew Zealand Maori0.0350200See
CHNChina Yunnan Province Bai0.0350128See
IDNIndonesia Sundanese and Javanese0.0350201See
INDIndia Kerala Malayalam speaking6.50.0320356See
CHNChina Yunnan Province Yao0.032066See
CANCanada Ojibwa NA-DHS_4 (G)6.30.031316See
IDNIndonesia Singaporean0.030050See
MEXMexico Hidalgo Mezquital Valley/ Otomi5.60.027872See
CANCanada Cree NA-DHS_3 (G)5.60.027818See
CHNChina Jingpo Minority5.20.0260105See
BOLBolivia/Chile Aymara NA-DHS_13 (G)5.00.025020See
CHLChile Huilliche NA-DHS_14 (G)5.00.025020See
IDNIndonesia Nusa Tenggara Islands0.024049See
RUSRussia Bashkortostan, Bashkirs4.20.0208120See
WSMSamoa pop20.020050See
LBNLebanon Niha el Shouff0.017061See
CHNChina Yunnan Province Wa0.0170119See
RUSRussia Bashkortostan, Tatars3.10.0156192See
USAUSA South Dakota Lakota Sioux0.0150302See
CHNChina Yunnan Province Nu0.0140107See
PRTPortugal Azores Terceira Island2.60.0132130See
FRAFrance Southeast2.30.0120130See
MEXMexico Chihuahua Tarahumara0.011044See
COKCook Islands0.010050See
TWNTaiwan Paiwan2.00.010051See
TWNTaiwan Ami pop 20.010050See
TWNTaiwan Bunun pop 20.010050See
CHNChina Yunnan Province Lahu0.009070See
CHNChina Yunnan Province Jinuo0.0050109See
BRABrazil Mixed0.0050108See
CHNChina Yunnan Province Lisu0.0050111See
USAUSA Spain Ancestry0.0020279See
USAUSA Arizona Gila River Pima0.00053000See
TWNTaiwan Tsou0.00.000051See
TWNTaiwan Rukai0.00.000050See
TWNTaiwan Atayal pop 20.000050See
TWNTaiwan Saisiat pop 20.000050See
TWNTaiwan Puyuma pop 20.000050See
TWNTaiwan Ami0.00.000098See
TWNTaiwan Puyuma0.00.000050See
TWNTaiwan Tao0.00.000050See
PHLPhilippines Ivatan0.00.000050See
PNGPapua New Guinea Lowland0.000047See
PNGPapua New Guinea Lowland Wosera0.000079See
PNGPapua New Guinea Highland0.000094See
TWNTaiwan Atayal0.00.0000106See
TWNTaiwan Taroko0.00.000055See
TWNTaiwan Saisiat0.00.000051See
TWNTaiwan Bunun0.00.0000101See
TWNTaiwan Tsou pop 20.000050See
TWNTaiwan Paiwan pop 20.000050See
TWNTaiwan Rukai pop 20.000050See
TWNTaiwan Orchid Island Yami0.000050See
BRABrazil Kaingang0.0000235See
COLColombia Bogota and Medellin Mestizo0.000065See
CHNChina Yunnan Province Drung0.000070See
KORSouth Korea pop 30.0000485See
IDNIndonesia Moluccan Islands0.000024See

Frequency data at lower resolution for this allele can be found in links below

Allele  Number of Populations 


* Allele Frequency: Total number of copies of the allele in the population sample (Alleles / 2n) in decimal format.
   Important: This field has been expanded to four decimals to better represent frequencies of large datasets (e.g. where sample size > 1000 individuals)
* Phenotype Frequency: Percentage of individuals who have the allele or gene (Individuals / n).
* Allele Frequencies shown in green were calculated from Phenotype Frequencies assuming Hardy-Weinberg proportions.

¹ IMGT/HLA Database - For more details of the allele.
² Distribution - Graphical distribution of the allele.
³ Haplotype Association - Find HLA haplotypes with this allele.
ª Notes - See notes for ambiguous combinations of alleles.

Allele frequency net database (AFND) 2020 update: gold-standard data classification, open access genotype data and new query tools
Gonzalez-Galarza FF, McCabe A, Santos EJ, Jones J, Takeshita LY, Ortega-Rivera ND, Del Cid-Pavon GM, Ramsbottom K, Ghattaoraya GS, Alfirevic A, Middleton D and Jones AR Nucleic Acid Research 2020, 48:D783-8.
Liverpool, U.K.

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