Allele Frequencies in World Populations

HLA Database Allele Report

The list below shows all populations in AFND that contains the allele. If an allele has an entry with a lower resolution this will be shown at the end.



Allele reported 60 time(s) and present in 56 population(s).

Population Phenotype
Frequency (%)
Distribution² Haplotype³
ENGEngland North West21.50.1160298See
NIRIreland Northern20.90.11101000See
CHNChina Inner Mongolia Region Ewenki0.101094See
RUSRussia Tundra Nentsi NA-DHS_1 (G)18.80.093816See
INDIndia Mumbai Maratha0.074091See
USAUSA San Francisco Caucasian0.0680220See
USAUSA Italy Ancestry0.0590273See
RUSRussia Bashkortostan, Bashkirs11.70.0583120See
CANCanada Cree NA-DHS_3 (G)11.10.055618See
POLPoland BMR10.10.052423595See
RUSRussian Federation Vologda Region9.20.0504119See
CHLChile Easter Island0.048021See
RUSRussia Nizhny Novgorod, Russians8.80.04471510See
SAUSaudi Arabia pop 30.040050See
CHNChina Inner Mongolia Autonomous Region Northeast6.90.0340496See
CANCanada Ojibwa NA-DHS_4 (G)6.30.031316See
ZAFSouth African Black5.00.0282142See
BRABrazil Rio de Janeiro Caucasian0.0278521See
RUSRussia Bashkortostan, Tatars5.20.0260192See
USAUSA African American pop 30.0260564See
CPVCape Verde Northwestern Islands0.024062See
INDIndia Kerala Malayalam speaking4.80.0240356See
BRABrazil Barra Mansa Rio State Caucasian0.0235405See
RUSRussia Belgorod region4.60.0229153See
USAUSA Mexican American Mestizo0.0200553See
CRICosta Rica African -Caribbean (G)4.00.0200102See
CPVCape Verde Southeastern Islands0.016062See
CHNChina Shandong Province Han0.015098See
BRABrazil Rio de Janeiro Parda0.0148170See
BRABrazil Rio de Janeiro Black0.014768See
CRICosta Rica Guanacaste Mestizo (G)2.80.0140110See
BRABrazil Barra Mansa Rio State Black0.013773See
ESPSpain, Canary Islands, Gran canaria island2.30.0116215See
SAUSaudi Arabia pop 6 (G)0.011428927See
INDIndia Andhra Pradesh Telugu Speaking2.20.0108186See
CHNChina Yunnan Province Lisu0.0100111See
CHNChina Zhejiang Han0.00871734See
CHNChina Han Guandong Province0.0070208See
MEXMexico Hidalgo Mezquital Valley/ Otomi1.40.006972See
SAUSaudi Arabia pop 51.30.0063158See
CHNChina Yunnan Province Nu0.0050107See
CHNChina Lijiang Naxi0.0050100See
VNMVietnam Kinh1.00.0050101See
LBYLibya Cyrenaica0.0040118See
CHNChina Yunnan Province Bai0.0040128See
CRICosta Rica Amerindians (G)0.80.0040125See
INDIndia Karnataka Kannada Speaking0.60.0030174See
TWNTaiwan Minnan and Hakka0.0030190See
NICNicaragua Mestizo (G)0.60.0030155See
USAUSA Spain Ancestry0.0020279See
CRICosta Rica Central Valley Mestizo (G)0.40.0020221See
HKGHong Kong Chinese HKBMDR HLA 11 loci0.30.00175266See
USAUSA Arizona Gila River Pima0.00093000See
GNBGuinea Bissau0.000065See
MARMorocco Nador Metalsa0.000099See
KORSouth Korea pop 30.0000485See
BRABrazil Guarani M bya0.000093See

Frequency data at lower resolution for this allele can be found in links below

Allele  Number of Populations 


* Allele Frequency: Total number of copies of the allele in the population sample (Alleles / 2n) in decimal format.
   Important: This field has been expanded to four decimals to better represent frequencies of large datasets (e.g. where sample size > 1000 individuals)
* Phenotype Frequency: Percentage of individuals who have the allele or gene (Individuals / n).
* Allele Frequencies shown in green were calculated from Phenotype Frequencies assuming Hardy-Weinberg proportions.

¹ IMGT/HLA Database - For more details of the allele.
² Distribution - Graphical distribution of the allele.
³ Haplotype Association - Find HLA haplotypes with this allele.
ª Notes - See notes for ambiguous combinations of alleles.

Allele frequency net database (AFND) 2020 update: gold-standard data classification, open access genotype data and new query tools
Gonzalez-Galarza FF, McCabe A, Santos EJ, Jones J, Takeshita LY, Ortega-Rivera ND, Del Cid-Pavon GM, Ramsbottom K, Ghattaoraya GS, Alfirevic A, Middleton D and Jones AR Nucleic Acid Research 2020, 48:D783-8.
Liverpool, U.K.

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