Allele Frequencies in World Populations

HLA Database » Allele Report

The list below shows all populations in AFND that contains the allele. If an allele has an entry with a lower resolution this will be shown at the end.



Allele reported 432 time(s) and present in 385 population(s).

Population Phenotype
Frequency (%)
Distribution² Haplotype³
PNGPapua New Guinea Podare0.314043See
MYSMalaysia Sabah Dusun0.313048See
PNGPapua New Guinea Iamega0.310079See
MYSMalaysia Sabah Kadazan0.281057See
PNGPapua New Guinea Wipim0.245055See
PNGPapua New Guinea Woigi0.231026See
PNGPapua New Guinea Abam0.222063See
PNGPapua New Guinea Kuru0.217046See
ITAItaly Sardinia pop237.00.20401129See
PNGPapua New Guinea Rual0.200050See
PNGPapua New Guinea Kapal0.192065See
PNGPapua New Guinea Wuroi0.162034See
PNGPapua New Guinea Highland pop20.161028See
JPNJapan pop 20.1550916See
JPNJapan Kyoto and Osaka0.1550165See
JPNJapan South28.00.1514125See
USAUSA NMDP Japanese0.147224582See
PNGPapua New Guinea Wonie0.147051See
JPNJapan pop 426.70.1440525See
JPNJapan Hyogo28.10.141032See
JPNJapan pop 30.14001018See
JPNJapan pop 1125.80.138662See
PNGPapua New Guinea South Gidra0.1380192See
JPNJapan pop 170.13703078See
JPNJapan pop 160.134918604See
PNGPapua New Guinea Highland0.132094See
JPNJapan Nagano24.60.131657See
JPNJapan Hyogo Osaka and Nagano0.1280195See
JPNJapan Hokkaido Wajin23.90.127671See
PNGPapua New Guinea Dorogori0.127059See
MYSMalaysia Sarawak Iban0.118051See
JPNJapan Central0.1150371See
JPNJapan pop 620.20.1066129See
JPNJapan Aichi19.60.106050See
NZLNew Zealand Polynesians with Full Ancestry14.30.095021See
PNGPapua New Guinea Ume0.094090See
KORSouth Korea pop 30.0920485See
PNGPapua New Guinea East New Britain Rabaul0.092060See
USAUSA Philippines0.0910105See
USAUSA NMDP Korean0.089477584See
USAUSA NMDP Filipino0.089350614See
KORSouth Korea pop 215.90.0890207See
CHNChina Guangxi Region Maonan0.0880108See
AUSAustralia Cape York Peninsula Aborigine0.0860103See
KORSouth Korea pop 10.0850324See
TWNTaiwan Tzu Chi Cord Blood Bank0.0840710See
KORSouth Korea pop 100.08244128See
MYSMalaysia Perak Grik Jehai0.080025See
JPNJapan Hokkaido Ainu0.080050See
PNGPapua New Guinea Eastern Highlands Goroka Asaro0.079057See
WSMWestern Samoa and Tokelau0.078051See
THAThailand North Dai Lue0.078096See
TWNTaiwan Han Chinese0.0770504See
KORSouth Korea pop 414.70.0764211See
CHNChina Yunnan Province Naxi0.0760118See
KORSouth Korea pop 60.0760800See
NZLNew Zealand Polynesians with Admixed History11.10.074027See
MYSMalaysia Kedah Kensiu14.30.071021See
TWNTaiwan pop10.0710539See
MNGMongolia Tsaatan0.0700144See
AREUnited Arab Emirates Abu Dhabi0.067352See
KORSouth Korea pop 110.0670149See
TWNTaiwan Tzu Chi Morrow Donor Registry0.066846682See
TWNTaiwan Tzu Chi Morrow Donor Registry Aborigine0.0665233See
PNGPapua New Guinea East New Britain Tolai0.065048See
HKGHong Kong Chinese BMDR0.06337595See
CHNChina Beijing and Xian0.0630171See
HKGHong Kong Chinese cord blood registry0.06263892See
CHNChina Zhejiang Han pop 20.0624833See
TWNTaiwan Aborigine pop 20.062048See
USAUSA NMDP Chinese0.061299672See
SAUSaudi Arabia11.80.060818See
CHNChina Harbin Korean0.0600201See
MYSMalaysia Kedah Baling Kensiu0.060025See
CHNChina Harbin Manchu pop 20.060050See
CHNChina Urumqi Han0.059059See
THAThailand Northeast pop 20.0590400See
TWNTaiwan pop 20.0590364See
CHNChina Marrow Donor Registry0.0580600See
USAUSA Asian pop 20.05801772See
PNGPapua New Guinea Trobriand Island0.056081See
MNGMongolia Tarialan Khoton0.055085See
TUNTunisia Ghannouch0.055082See
THAThailand Northeast0.055066See
CHNChina Jiangsu Han0.05503238See
MNGMongolia Hoton0.054085See
ETHEthiopia Oromo0.054083See
SAUSaudi Arabia pop 6 (G)0.053228927See
CHNChina Urumqi Uyghur8.80.053057See
CHNChina Southwest Dai0.0520124See
THAThailand Kamphaeng Phet0.051097See
ETHEthiopia Amhara0.051098See
COKCook Islands Rarotonga0.051078See
MNGMongolia Khalkha0.0500200See
PRTPortugal Center0.050050See
CHNChina pop19.70.0500103See
CHNChina Hubei Han9.90.04943732See
AUSAustralia Kimberly Aborigine0.049041See
USAUSA NMDP Vietnamese0.048543540See
GMBGambia pop 39.00.0475939See
USAUSA NMDP Hawaiian or other Pacific Islander0.047011499See
CHNChina Jiangsu Province Han0.0470334See
CHNChina Hong Kong and Singapore0.0470135See
RUSRussia Tuva pop30.045044See
VNMVietnam Hanoi Kinh0.0440103See
NZLNew Zealand Maori with Full Ancestry8.70.044046See
MYSMalaysia Peninsular Chinese8.80.0438194See
ISRIsrael Ethiopia Jews0.04355928See
DEUGermany DKMS - China minority0.04331282See
HRVCroatia Krk Island Dubasnica0.043023See
CHNChina Canton Han0.0420264See
CHNChina Beijing Shijiazhuang Tianjian Han0.0410618See
THAThailand Bangkok pop 20.040050See
RUSRussia Tuva pop 20.0400169See
MNGMongolia Khalkha pop 20.0400202See
ISRIsrael Iraq Jews0.039613270See
PNGPapua New Guinea Lowland0.039047See
PNGPapua New Guinea Lowland Roro0.038026See
VNMVietnam Hanoi Kinh pop 20.0380170See
CHNChina Harbin Manchu0.0380172See
ISRIsrael Non Ashkenazi Jews0.038080See
RUSRussia Tuva0.0380190See
AREUnited Arab Emirates Pop 10.0380570See
RUSRussia Transbaikal Territory Buryats7.00.0370150See
MARMorocco Souss Region0.037098See
MEXMexico Nuevo Leon Mestizo7.50.037040See
MYSMalaysia Kelantan7.10.036028See
USAUSA NMDP Caribean Indian0.036014339See
ISRIsrael YemenJews0.035315542See
USAUSA NMDP Caribean Hispanic0.0353115374See
FJIFiji Viti Levu Island0.035057See
MYSMalaysia Peninsular Malay6.50.0342951See
COLColombia Northwest Tule0.034029See
ISRIsrael Ashkenazi Jews0.032080See
INDIndia Andhra Pradesh Golla0.0320111See
LBNLebanon Kafar Zubian0.032094See
MEXMexico Highlands Mestizos5.60.0310160See
ZAFSouth Africa Worcester6.00.0310159See
IDNIndonesia Singaporean0.030050See
DZAAlgeria Oran0.0300100See
CRICosta Rica and Panama Mestizo0.030056See
USAUSA Mexican American Mestizo pop 30.0300116See
COLColombia Bogotá Cord Blood5.80.02941463See
ARGArgentina Rio Negro Mapuche0.029034See
PRTMadeira pop 20.0290173See
RUSRussia Sakhalin Island Nivkhi0.028053See
USAUSA San Diego5.40.0280496See
BRABrazil South Caucasian0.027873See
USAUSA Southern California Mestizo5.50.027873See
ISRIsrael Yemenite Jews0.027076See
GRCGreece pop35.30.0268246See
ISRIsrael Libyan Jews0.0260119See
IDNIndonesia Java0.026058See
DZAAlgeria pop 25.00.0253106See
COLColombia West Cauca0.025020See
COLColombia West Embera0.025020See
USAUSA Colorado Univ Cord Blood Bank Asian0.0250100See
ESPSpain Barcelona5.00.0250941See
CHNChina Wuhan5.00.0250121See
IDNIndonesia Moluccan Islands0.025024See
ISRIsrael Iranian Jews0.0250101See
ISRIsrael Ethiopian Jews0.0250122See
SDNSudan Mixed5.00.0250200See
USAUSA NMDP Hispanic South or Central American0.0243146714See
CHLChile Santiago0.0240920See
BORBorneo Bandjarmasin0.024021See
VNMVietnam HoaBinh Muong0.024083See
BRABrazil Southeast Caucasian4.80.0240103See
BRABrazil Southeast Mixed Race4.80.024042See
MNGMongolia Ulaanbaatar Khalkha0.024041See
INDIndia North4.70.023785See
ENGEngland pop 64.00.0230177See
RUSRussia Siberia Irkutsk Tofalar0.023043See
NCLNew Caledonia0.023065See
PNGPapua New Guinea Madang0.023065See
MEXMexico Oaxaca Zapotec0.023090See
MEXMexico Mexico City Mestizo pop 30.0230256See
TZATanzania Maasai4.00.0229336See
BRABrazil Paraná Caucasian4.50.0226641See
USAUSA NMDP Mexican or Chicano0.0222261235See
CHNChina Yunnan Bulang0.0220116See
ISRIsrael Moroccan Jews0.0220113See
ZWEZimbabwe Harare Shona0.0220230See
ISRIsrael Libya Jews0.02193739See
USAUSA NMDP Southeast Asian0.021127978See
BRABrazil North East Mixed0.0210205See
ISRIsrael Tunisia Jews0.02069070See
GRCCretan Islanders0.0202124See
MYSMalaysia Patani4.00.020025See
PRTPortugal South0.020049See
RUSRussia Siberia NW of Sakhalin Island Nivkh0.020032See
RUSRussia Siberia Khabarovsk Evenki0.020025See
BRABrazil Mixed0.0200108See
MYSMalaysia Sarawak Bau Bidayuh0.020025See
MYSMalaysia Sarawak Bidayuh0.020050See
DEUGermany DKMS - Italy minority0.01981159See
USAUSA NMDP African0.019728557See
MEXMexico Mexico City Tlalpan3.90.0197330See
COLColombia North Wiwa El Encanto0.019252See
USAUSA Hispanic pop 20.01931999See
DEUGermany DKMS - Portugal minority0.01911176See
NZLNew Zealand Maori with Admixed History3.80.0190105See
MYSMalaysia Mandailing3.70.019027See
SAUSaudi Arabia Guraiat and Hail3.40.0190213See
GRCGreece Crete0.0190135See
MNGMongolia Oold0.0190104See
FRAFrance Southeast3.80.0190130See
GRCGreece pop 60.0186242See
ISRIsrael Arab pop 20.018512301See
ESPSpain (Catalunya, Navarra, Extremadura, Aaragón, Cantabria,3.60.01834335See
ESPSpain Granada0.0180280See
USAUSA Colorado Univ Cord Blood Bank Hispanic0.01801058See
USAUSA Southeast African American3.60.0180112See
TURTurkey pop 10.0180250See
PRTAzores Central Islands0.018059See
IDNIndonesia Nusa Tenggara Islands0.018049See
ISRIsrael Iran Jews0.01798153See
DEUGermany DKMS - Spain minority0.01721107See
ESPSpain Northwest Lugo3.40.0171145See
IDNIndonesia Java Western3.40.0170236See
FRAFrance South0.0170350See
MYSMalaysia Champa3.50.017029See
USAUSA NMDP Caribean Black0.016933328See
USAUSA NMDP Middle Eastern or North Coast of Africa0.016770890See
NICNicaragua Managua3.00.0165339See
ISRIsrael Morocco Jews0.016236718See
CHNChina Xinjiang Province Uyghur0.016092See
PRTAzores Terceira Island0.0160130See
TUNTunisia Gabes Arab0.016096See
CHNChina Yunnan Province Han pop 20.0160129See
TUNTunisia Gabes0.015795See
USAUSA NMDP African American pop 20.0153416581See
CHNChina, Xinjiang Uyghur Autonomous Region Kazakh3.00.015252See
GAZGaza Palestinians0.0150165See
IRNIran pop 30.0150100See
MEXMexico Guanajuato and Jalisco Mestizo3.00.0150101See
TUNTunisia pop 30.0150104See
CUBCuba Mixed0.015078See
CHNChina Yunnan Province Han0.0150101See
IRNIran Baloch0.0150100See
IRNIran Fars Parsi0.014073See
SCOScotland Orkney2.90.014099See
ISRIsrael Arab0.0140109See
INDIndia Northeast UCBB2.70.0135296See
PRTPortugal Azores Terceira Island2.60.0132130See
DEUGermany DKMS - Greece minority0.01321894See
ITAItaly pop 50.0130975See
MYSMalaysia Pahang Semai2.60.013038See
USAUSA African American pop 70.0130193See
GEOGeorgia Caucasus Tbilisi0.0126119See
ESPSpain Murcia0.0120173See
USAUSA Colorado Univ Cord Blood Bank African American0.0120261See
RUSRussia Chuvash0.012082See
USAUSA Caucasian Pittsburgh2.40.0120177See
CHNChina Urumqi Kazak0.012042See
GRCGreece pop22.40.0120120See
ISRIsrael Argentina Jews0.01204307See
ISRIsrael USA Jews0.01136058See
FRAFrance French Bone Marrow Donor Registry0.011042623See
BOLBolivia La Paz Aymaras0.011087See
ZAFSouth Africa Caucasians0.0110102See
USAUSA Philadelphia Caucasian2.10.0110141See
CODCongo Kinshasa Bantu2.20.011090See
ITAItaly Central0.0110380See
PRTPortugal North0.011046See
RWARwanda Kigali Hutu and Tutsi0.0110281See
DEUGermany DKMS - Turkey minority0.01054856See
MEXMexico Mexico City Mestizo population0.0105143See
COLColombia Wayu from Guajira Peninsula0.010448See
MEXMexico Jaltepec Mazahuas0.010050See
MEXMexico Mazahua0.010065See
BRABrazil Mato Grosso do Sul0.0100203See
USAUSA NMDP American Indian South or Central America0.01005926See
ARMArmenia combined Regions0.0100100See
FRAFrance Rennes0.0100200See
FRAFrance Rennes pop 30.0100200See
CZECzech Republic pop 22.00.010099See
GRCGreece pop 40.010098See
CZECzech Republic0.0100106See
MKDMacedonia pop 10.0100158See
FRAFrance West2.00.0100100See
USAUSA NMDP North American Amerindian0.009835791See
USAUSA African American pop 40.00962411See
MYSMalaysia Peninsular Indian1.80.0092271See
INDIndia East UCBB1.80.00922403See
USAUSA NMDP Alaska Native or Aleut0.00901376See
USAUSA San Francisco Caucasian0.0090220See
SGPSingapore Riau Malay0.0090132See
DEUGermany pop 31.80.0090111See
HRVCroatia Krk Island0.0090212See
RUSRussia Siberia Eskimo0.009070See
ISRIsrael Poland Jews0.008813871See
DEUGermany DKMS - United Kingdom minority0.00821043See
CANCanada British Columbia Athabaskan0.008062See
STPSao Tome Island Forro0.008066See
MEXMexico Tixcacaltuyub Maya0.007567See
USAUSA NMDP South Asian Indian0.0075185391See
INDIndia Central UCBB1.50.00734204See
BOLBolivia Quechua0.007269See
INDIndia Uttar Pradesh0.0070202See
USAUSA Colorado Univ Cord Blood Bank Caucasian0.00703830See
USAUSA African American Bethesda1.40.0070187See
IDNIndonesia Java Yogyakarta Region0.007062See
RUSRussia Siberia Ulchi0.007073See
USAUSA Minnesota Olmsted0.0070339See
INDIndia South UCBB1.40.006911446See
INDIndia North UCBB1.40.00685849See
USAUSA NMDP European Caucasian0.00671242890See
ECUEcuadorean Amerindians0.006775See
DEUGermany DKMS - France minority0.00611406See
GRCGreece pop 81.20.006083See
GEOGeorgia Svaneti Region Svan0.006080See
CAFCentral African Republic Aka Pygmy1.20.006093See
ARGArgentina Rosario Toba1.20.006086See
MKDMacedonia pop 20.006080See
USAUSA Eastern European0.0060558See
ESPSpain Las Alpujarras0.005985See
DEUGermany DKMS - Bosnia and Herzegovina minority0.00581028See
INDIndia West UCBB1.10.00565829See
DEUGermany DKMS - Romania minority0.00531234See
KENKenya, Nyanza Province, Luo tribe1.00.0050100See
INDIndia Northeast Sunni0.0050188See
INDIndia Northeast Kayastha0.0050190See
CHLChile Santiago Mixed1.00.005070See
ITAItaly Rome1.00.0050100See
USAUSA South Texas Hispanic0.0050194See
ARGArgentina Buenos Aires1.00.0050466See
MEXMexico Oaxaca Mixtec0.0050103See
INDIndia Delhi0.0050112See
DEUGermany DKMS - Netherlands minority0.00471374See
DEUGermany pop 80.004539689See
ISRIsrael Ashkenazi Jews pop 20.0040132See
AUSAustralia Yuendumu Aborigine0.0040191See
ARGArgentina Gran Chaco Eastern Toba0.0040135See
NIRIreland Northern0.70.00401000See
GTMGuatemala Mayan0.0040132See
IRLIreland South0.80.0040250See
THAThailand Bangkok pop 30.0040187See
SWESweden Southern Sami0.0040130See
DEUGermany DKMS - German donors0.00393456066See
INDIndia Tamil Nadu0.00392492See
DEUGermany DKMS - Austria minority0.00381698See
HRVCroatia pop 40.00364000See
SVNSlovenia pop 20.70.0035140See
USAUSA Caucasian0.70.003561655See
ISRIsrael Ashkenazi Jews pop 30.00354625See
CZECzech Republic NMDR0.00315099See
DEUGermany pop 60.00318862See
SWESweden Northern Sami0.0030154See
INDIndia Northeast Vaish0.0030198See
INDIndia Northeast Shia0.0030190See
DEUGermany Essen0.60.0030174See
USAUSA Caucasian Houston0.60.0030194See
MKDMacedonia pop 30.0030172See
NLDNetherlands Leiden0.00301305See
LKASri Lanka Colombo0.60.0030714See
BRABrazil Puyanawa0.70.0030150See
DEUGermany DKMS - Croatia minority0.00292057See
RUSRussia Karelia0.00281075See
POLPoland DKMS0.002520653See
MEXMexico Chiapas Lacandon Mayans0.0023218See
USAUSA San Antonio Caucasian0.0023222See
ISRIsrael USSR Jews0.002345681See
ISRIsrael Bukhara Jews0.00212317See
ISRIsrael Druze0.00215914See
MEXMexico Mexico City Mestizo pop 20.0021234See
USAUSA Caucasian pop 50.0020268See
USAUSA Caucasian pop 40.00191070See
ISRIsrael Kavkazi Jews0.00122840See
ISRIsrael Georgia Jews0.00034471See
BRABrazil Vale do Ribeira Quilombos0.00.0000144See
STPSao Tome Island Angolar0.000032See
ARGArgentina Chubut Tehuelche0.000023See
ARGArgentina Salta Wichi0.000024See
PRYParaguay Lengua0.000017See
INDIndia Northeast Lachung0.000058See
INDIndia Northeast Mech0.000063See
INDIndia Northeast Rajbanshi0.000098See
INDIndia Northeast Mathur0.0000155See
INDIndia Northeast Rastogi0.0000196See
CZECzech Republic Romani0.00.000034See
TUNTunisia Jerba Berber0.000055See
TUNTunisia Matmata Berber0.000081See
WSMSamoa West0.000022See
PNGPapua New Guinea Lowland Wosera0.000079See
LBNLebanon Niha el Shouff0.000061See
LBNLebanon Yuhmur0.000082See
PRTAzores Oriental Islands0.000043See
ITAItaly North pop 30.00.000097See
ITAItaly Bergamo0.00.0000101See
USAUSA Alaska Yupik0.0000252See
CANCanada British Columbia Penutian0.000026See
BRABrazil Guarani Nandeva0.000086See
USAUSA Caucasian Bethesda0.00.0000307See
BRABrazil Guarani M bya0.000093See
BRABrazil Kaingang0.0000235See
ARGArgentina Gran Chaco Mataco Wichi0.000049See
ARGArgentina Gran Chaco Western Toba Pilaga0.000019See
BRABrazil Central Plateau Xavante0.000074See
IRNIran Yazd Zoroastrian0.000065See
RUSRussia Siberia Negidal0.000035See
RUSRussia Siberia Kushun Buryat0.000025See
RUSRussia Siberia Khanty Mansi0.000068See
RUSRussia Tuva Todja0.000022See
COLColombia Bogota and Medellin Mestizo0.000065See
RUSRussia Siberia Chukotka Peninsula Chukchi0.000059See
RUSRussia Siberia Chukotka Peninsula Eskimo0.000080See
RUSRussia Siberia Chukchi0.000071See
RUSRussia Siberia Sulamai Ket0.000022See
RUSRussia Siberia Polygus Evenk0.000035See
RUSRussia Siberia North East Kamchatka Koryak0.000092See
RUSRussia Siberia Gvaysugi Udege0.000025See

Frequency data at lower resolution for this allele can be found in links below

Allele  Number of Populations 


* Allele Frequency: Total number of copies of the allele in the population sample (Alleles / 2n) in decimal format.
   Important: This field has been expanded to four decimals to better represent frequencies of large datasets (e.g. where sample size > 1000 individuals)
* Phenotype Frequency: Percentage of individuals who have the allele or gene (Individuals / n).
* Allele Frequencies shown in green were calculated from Phenotype Frequencies assuming Hardy-Weinberg proportions.

¹ IMGT/HLA Database - For more details of the allele.
² Distribution - Graphical distribution of the allele.
³ Haplotype Association - Find HLA haplotypes with this allele.
ª Notes - See notes for ambiguous combinations of alleles.


Allele frequency net database (AFND) 2020 update: gold-standard data classification, open access genotype data and new query tools
Gonzalez-Galarza FF, McCabe A, Santos EJ, Jones J, Takeshita LY, Ortega-Rivera ND, Del Cid-Pavon GM, Ramsbottom K, Ghattaoraya GS, Alfirevic A, Middleton D and Jones AR Nucleic Acid Research 2020, 48:D783-8.
Liverpool, U.K.

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