Allele Frequencies in World Populations

HLA Database » Allele Report

The list below shows all populations in AFND that contains the allele. If an allele has an entry with a lower resolution this will be shown at the end.



Allele reported 183 time(s) and present in 130 population(s).

Population Phenotype
Frequency (%)
Distribution² Haplotype³
PRYParaguay/Argentina Ache NA-DHS_24 (G)100.00.833313See
PRYParaguay Aché0.741087See
BRABrazil East Amazon0.634041See
VENVenezuela Sierra de Perija Yucpa0.614073See
MEXMexico Mayan pop 20.5740163See
COLColombia/Brazil Ticuna Tarapaca NA-DHS_22 (G)84.20.552619See
COLColombia Amazon Region Coreguaje0.467030See
COLColombia/Brazil Ticuna Arara NA-DHS_21 (G)73.30.466717See
MEXMexico Chiapas Lacandon Mayans0.3624218See
BRABrazil Ticuna0.316050See
BRABrazil Guarani M bya0.269093See
ARGArgentina Salta Wichi pop 242.10.210019See
COLColombia Wayu from Guajira Peninsula0.208348See
MEXMexico Chichen Itza Maya (prehispanic)0.191547See
PERPeru Lamas City Lama0.169083See
COLColombia Wayuu NA-DHS_15 (G)33.30.166715See
COLColombia Guajira Peninsula Wayuu0.134088See
MEXMexico Mayan0.133016See
COLColombia West Waunana0.117030See
COLColombia Embera NA-DHS_19 (G)21.40.107114See
MEXMexico San Vicente Tancuayalab Teenek/Huastecos0.103853See
MEXMexico Huasteca Region Teenek0.102055See
COLColombia East Amazon Region Nukak0.100020See
ARGArgentina Gran Chaco Western Toba Pilaga0.093019See
COLColombia Northwest Tule0.086029See
MEXMexico Oaxaca Jamiltepec Mixtec0.078096See
MEXMexico Mazatecan0.077089See
MEXMexico Mixtec0.077097See
ARGArgentina Gran Chaco Mataco Wichi0.076049See
BRABrazil Guarani Nandeva0.070086See
ARGArgentina Salta Wichi0.062024See
ARGArgentina Gran Chaco Eastern Toba0.0620135See
BRABrazil Puyanawa12.00.0600150See
MEXMexico Tixcacaltuyub Maya0.059767See
PRYParaguay/Argentina Guarani NA-DHS_23 (G)10.00.050010See
COLColombia Waunana NA-DHS_20 (G)10.00.050020See
COLColombia West Embera0.050020See
USAUSA New Mexico Zuni0.050051See
ARGArgentina Chiriguano7.10.045054See
BRABrazil Guarani Kaiowa0.0420155See
USAUSA Southern California Mestizo8.20.041873See
MEXMexico Veracruz Xalapa8.30.041784See
MEXMexico Nuevo Leon Mestizo7.50.037040See
ECUEcuador Cayapa0.0360183See
USAUSA NMDP Caribean Indian0.035014339See
USAUSA NMDP Caribean Hispanic0.0333115374See
COLColombia Inga NA-DHS_11 (G)6.30.031216See
COLColombia Antioquia Paisa0.0300100See
BRABrazil North East Mixed0.0290205See
MEXMexico Mexico City Mestizo pop 30.0290256See
MEXMexico Highlands Mestizos5.60.0280160See
GTMGuatemala Mayan0.0260132See
NICNicaragua Managua4.80.0254339See
USAUSA South Texas Hispanic0.0250194See
BRABrazil Mato Grosso do Sul0.0250203See
MEXMexico Mexico City Mestizo population0.0245143See
USAUSA Hispanic pop 20.02351999See
MEXMexico Chihuahua Tarahumara0.023044See
USAUSA Mexican American Mestizo0.0220553See
USAUSA Mexican American Mestizo pop 30.0220116See
BRABrazil Paraná Caucasian4.40.0218641See
USAUSA NMDP Hispanic South or Central American0.0207146714See
BRABrazil Mixed0.0200108See
USAUSA Spain Ancestry0.0200279See
MEXMexico Mexico City Mestizo pop 20.0192234See
COLColombia North Eastern Plains Sikuani0.019027See
COLColombia Bogotá Cord Blood3.70.01881463See
BRABrazil Terena3.40.017060See
MEXMexico Oaxaca Zapotec0.017090See
USAUSA NMDP Mexican or Chicano0.0156261235See
MEXMexico Oaxaca Mixtec0.0150103See
AUSAustralia Cape York Peninsula Aborigine0.0150103See
COLColombia Bogota and Medellin Mestizo0.015065See
BOLBolivia Quechua0.014569See
USAUSA Colorado Univ Cord Blood Bank Hispanic0.01301058See
MEXMexico Mexico City Tlalpan2.40.0121330See
IDNIndonesia Nusa Tenggara Islands0.012049See
AUSAustralia Kimberly Aborigine0.012041See
ARGArgentina Rosario Toba2.30.012086See
BRABrazil Southeast Mixed Race2.40.012042See
COLColombia San Basilio de Palenque0.012042See
MEXMexico Chihuahua Chihuahua City Pop 22.30.011488See
CUBCuba Mixed0.007078See
USAUSA Caucasian pop 50.0070268See
ECUEcuadorean Amerindians0.006775See
BRABrazil Kaingang0.0060235See
ARGArgentina Buenos Aires1.00.0050466See
BRABrazil Southeast Caucasian1.00.0050103See
ESPSpain Andalusia0.005099See
PERPeru Titikaka Lake Uro0.0050105See
PERPeru Titikaka Lake Uros0.0050105See
USAUSA San Antonio Caucasian0.0045222See
CHNChina Wuhan0.80.0040121See
USAUSA NMDP American Indian South or Central America0.00405926See
USAUSA Arizona Gila River Amerindian0.0030492See
USAUSA African American pop 70.0030193See
CHLChile Santiago0.0026920See
USAUSA South Dakota Lakota Sioux0.0020302See
USAUSA San Diego0.40.0020496See
USAUSA NMDP Caribean Black0.001833328See
USAUSA African American pop 30.0010564See
ITAItaly Sardinia pop20.10.00101129See
USAUSA African American pop 40.00082411See
ESPSpain Barcelona0.10.0005941See
DEUGermany DKMS - Italy minority0.00041159See
USAUSA NMDP North American Amerindian0.000435791See
ISRIsrael Argentina Jews0.00034307See
USAUSA NMDP Hawaiian or other Pacific Islander0.000311499See
USAUSA Colorado Univ Cord Blood Bank Caucasian0.00033830See
USAUSA NMDP Middle Eastern or North Coast of Africa0.000270890See
USAUSA NMDP African American pop 20.0001416581See
USAUSA NMDP Filipino0.000150614See
USAUSA NMDP European Caucasian0.00011242890See
USAUSA NMDP African0.000128557See
JPNJapan pop 160.000118604See
ESPSpain (Catalunya, Navarra, Extremadura, Aaragón, Cantabria,0.00.00014335See
HKGHong Kong Chinese BMDR0.00017595See
USAUSA NMDP Japanese0.000124582See
ISRIsrael Arab pop 20.000012301See
USAUSA NMDP Vietnamese0.000043540See
USAUSA NMDP South Asian Indian0.0000185391See
USAUSA NMDP Southeast Asian0.000027978See
USAUSA NMDP Chinese0.000099672See
DEUGermany DKMS - German donors0.00003456066See
ISRIsrael USSR Jews0.000045681See
USAUSA NMDP Korean0.000077584See
USAUSA Asian pop 20.00001772See
USAUSA Caucasian pop 40.00001070See
USAUSA Caucasian Houston0.00.0000194See
USAUSA Caucasian Pittsburgh0.00.0000177See
USAUSA Caucasian Bethesda0.00.0000307See
USAUSA African American Bethesda0.00.0000187See
USAUSA Philadelphia Caucasian0.00.0000141See
WSMSamoa West0.000022See
ITAItaly pop 50.0000975See
KORSouth Korea pop 20.00.0000207See
KORSouth Korea pop 30.0000485See
MARMorocco Nador Metalsa0.000099See
MARMorocco Settat Chaouya0.000098See
ITAItaly Rome0.00.0000100See
ITAItaly North pop 30.00.000097See
ITAItaly Bergamo0.00.0000101See
IDNIndonesia Moluccan Islands0.000024See
IDNIndonesia Singaporean0.000050See
USAUSA Alaska Yupik0.0000252See
USAUSA Colorado Univ Cord Blood Bank African American0.0000261See
USAUSA Colorado Univ Cord Blood Bank Asian0.0000100See
PRYParaguay Lengua0.000017See
TWNTaiwan Aborigine pop 20.000048See
USAUSA Caucasian0.00.000061655See
PNGPapua New Guinea Lowland0.000047See
PNGPapua New Guinea Lowland Wosera0.000079See
PNGPapua New Guinea Highland0.000094See
PNGPapua New Guinea East New Britain Tolai0.000048See
PNGPapua New Guinea Highland pop20.000028See
MKDMacedonia pop 10.0000158See
PERPeru Quechua0.000044See
NIRIreland Northern0.00.00001000See
NLDNetherlands Leiden0.00001305See
DEUGermany pop 80.000039689See
CZECzech Republic0.0000106See
FRAFrance West0.00.0000100See
FRAFrance Rennes pop 30.0000200See
ESPSpain Murcia0.0000173See
CHNChina Urumqi Uyghur0.00.000057See
CODCongo Kinshasa Bantu0.00.000090See
BRABrazil South Caucasian0.000073See
BRABrazil Vale do Ribeira Quilombos0.00.0000144See
BRABrazil Central Plateau Xavante0.000074See
CAFCentral African Republic Aka Pygmy0.00.000093See
CANCanada British Columbia Athabaskan0.000062See
CANCanada British Columbia Penutian0.000026See
ARGArgentina Rio Negro Mapuche0.000034See
ARGArgentina Chubut Tehuelche0.000023See
BORBorneo Bandjarmasin0.000021See

Frequency data at lower resolution for this allele can be found in links below

Allele  Number of Populations 


* Allele Frequency: Total number of copies of the allele in the population sample (Alleles / 2n) in decimal format.
   Important: This field has been expanded to four decimals to better represent frequencies of large datasets (e.g. where sample size > 1000 individuals)
* Phenotype Frequency: Percentage of individuals who have the allele or gene (Individuals / n).
* Allele Frequencies shown in green were calculated from Phenotype Frequencies assuming Hardy-Weinberg proportions.

¹ IMGT/HLA Database - For more details of the allele.
² Distribution - Graphical distribution of the allele.
³ Haplotype Association - Find HLA haplotypes with this allele.
ª Notes - See notes for ambiguous combinations of alleles.


Allele frequency net database (AFND) 2020 update: gold-standard data classification, open access genotype data and new query tools
Gonzalez-Galarza FF, McCabe A, Santos EJ, Jones J, Takeshita LY, Ortega-Rivera ND, Del Cid-Pavon GM, Ramsbottom K, Ghattaoraya GS, Alfirevic A, Middleton D and Jones AR Nucleic Acid Research 2020, 48:D783-8.
Liverpool, U.K.

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