Allele Frequencies in World Populations

HLA Database » Allele Report

The list below shows all populations in AFND that contains the allele. If an allele has an entry with a lower resolution this will be shown at the end.



Allele reported 468 time(s) and present in 428 population(s).

Population Phenotype
Frequency (%)
Distribution² Haplotype³
SGPSingapore SGVP. Indian INS0.903086See
SGPSingapore SGVP Malay MAS0.423089See
ESPSpain Arratia Valley Basque0.313083See
ESPSpain Las Alpujarras0.294185See
TUNTunisia Ghannouch0.287082See
ISRIsrael Libyan Jews0.2670119See
CUBCuba Mixed0.261078See
RUSRussia Siberia Kushun Buryat0.260025See
ESPSpain Gipuzkoa Basque0.2580100See
INDIndia Northeast Vaish0.2570198See
CAFCentral African Republic Aka Pygmy42.90.244093See
INDIndia Northeast Mathur0.2390155See
ISRIsrael Morocco Jews0.238636718See
ISRIsrael Libya Jews0.23323739See
ESPSpain Catalonia Girona0.232088See
SAUSaudi Arabia Guraiat and Hail37.20.2270213See
COLColombia Northwest Choco0.225020See
IRNIran Yazd Zoroastrian0.223065See
ISRIsrael Yemenite Jews0.221076See
ETHEthiopia Oromo0.217083See
LKASri Lanka Colombo38.00.2160714See
ISRIsrael Bukhara Jews0.21432317See
INDIndia East UCBB37.60.21142403See
INDIndia Northeast Kayastha0.2110190See
TUNTunisia Gabes0.205295See
PRTAzores Oriental Islands0.205043See
MARMorocco Souss Region0.205098See
ESPSpain North Cantabria0.205083See
ETHEthiopia Amhara0.204098See
CZECzech Republic pop 236.40.202599See
LBNLebanon Yuhmur0.198082See
INDIndia Lucknow38.00.1980123See
IRNIran Yazd0.196456See
INDIndia Northeast Rastogi0.1960196See
TUNTunisia Gabes Arab0.191096See
INDIndia Uttar Pradesh0.1880202See
PRTAzores Terceira Island0.1860130See
CHNChina, Xinjiang Uyghur Autonomous Region Uyghur37.00.184871See
ISRIsrael Moroccan Jews0.1810113See
ISRIsrael Tunisia Jews0.17989070See
ESPSpain Pas Valley0.179088See
ESPSpain Murcia0.1790173See
TUNTunisia Matmata Berber0.179081See
ISRIsrael YemenJews0.178415542See
ESPSpain Andalusia0.177099See
INDIndia Tamil Nadu0.17682492See
RUSRussia Siberia Khanty Mansi0.176068See
PRTPortugal Azores Terceira Island31.60.1754130See
INDIndia Delhi0.1750112See
PRTPortugal North0.174046See
USAUSA Philadelphia Caucasian29.80.1740141See
PRTMadeira pop 20.1730173See
TUNTunisia pop 20.1700111See
ESPSpain (Catalunya, Navarra, Extremadura, Aaragón, Cantabria,31.00.16964335See
USAUSA NMDP South Asian Indian0.1695185391See
INDIndia South UCBB30.60.169111446See
ESPSpain North Cabuerniga0.168095See
CHNChina Urumqi Uyghur26.30.167057See
ESPSpain Barcelona30.00.1630941See
MARMorocco Settat Chaouya0.163098See
IRLIreland South29.60.1620250See
CZECzech Republic0.1620106See
MARMorocco Atlantic Coast Chaouya0.161098See
CZECzech Republic Romani29.40.159734See
SAUSaudi Arabia29.40.159718See
DEUGermany DKMS - Portugal minority0.15941176See
INDIndia Central UCBB28.50.15934204See
INDIndia Northeast Sunni0.1590188See
INDIndia North UCBB28.90.15875849See
FRAFrance French Bone Marrow Donor Registry0.158642623See
CHNChina Jiangsu Han0.15803238See
ITAItaly Central0.1580380See
ITAItaly North pop 328.90.155097See
INDIndia West UCBB28.20.15475829See
DEUGermany DKMS - Spain minority0.15451107See
RUSRussia Bering Island Aleuts0.1538104See
USAUSA San Antonio Caucasian0.1509222See
SGPSingapore SGVP Chinese CHS0.150096See
RUSRussia Transbaikal Territory Buryats29.00.1470150See
INDIndia Northeast Shia0.1470190See
RUSRussia Chuvash0.146082See
USAUSA Caucasian Bethesda25.50.1450307See
POLPoland DKMS0.144920653See
AREUnited Arab Emirates Abu Dhabi0.144252See
SCOScotland Orkney27.90.144099See
PRTPortugal South0.143049See
PRTAzores Central Islands0.143059See
MYSMalaysia Kelantan25.00.143028See
CZECzech Republic NMDR0.14285099See
DEUGermany DKMS - Austria minority0.14251698See
USAUSA NMDP Caribean Indian0.142014339See
ISRIsrael Ethiopia Jews0.14075928See
PRTPortugal Center0.140050See
INDIndia Northeast Rajbanshi0.139098See
USAUSA NMDP Caribean Hispanic0.1389115374See
BRABrazil Paraná Caucasian25.40.1381641See
ENGEngland Bedfordshire25.70.1380354See
INDIndia Northeast Lachung0.138058See
DEUGermany DKMS - United Kingdom minority0.13761043See
DZAAlgeria Oran0.1360100See
IDNIndonesia Java Western25.40.1360236See
USAUSA NMDP Southeast Asian0.135627978See
ARGArgentina Buenos Aires25.10.1350466See
MYSMalaysia Peninsular Indian23.20.1347271See
USAUSA NMDP European Caucasian0.13421242890See
SVNSlovenia pop 225.00.1339140See
ISRIsrael USA Jews0.13316058See
ISRIsrael Ashkenazi Jews pop 30.13314625See
IRNIran Gorgan0.133064See
ENGEngland pop 625.40.1330177See
CHNChina Jiangsu Province Han0.1324334See
ESPSpain Tenerife Island0.132083See
USAUSA Colorado Univ Cord Blood Bank Caucasian0.13203830See
DEUGermany DKMS - France minority0.13191406See
BRABrazil Southeast Caucasian26.20.1310103See
ISRIsrael Ashkenazi Jews pop 20.1300132See
DEUGermany pop 324.30.1299111See
ITAItaly Bergamo24.70.1290101See
ISRIsrael Arab0.1280109See
CHNChina Harbin Manchu0.1280172See
TUNTunisia Jerba Berber0.128055See
USAUSA Caucasian Pittsburgh25.60.1280177See
ISRIsrael USSR Jews0.127945681See
GAZGaza Palestinians0.1270165See
ISRIsrael Poland Jews0.126213871See
USAUSA Caucasian pop 40.12601070See
DEUGermany DKMS - Italy minority0.12511159See
ITAItaly pop 50.1250975See
USAUSA Eastern European0.1250558See
RUSRussia Bashkortostan, Bashkirs22.50.1250120See
DEUGermany DKMS - German donors0.12493456066See
CHNChina pop123.30.1240103See
FRAFrance Rennes0.1230200See
ISRIsrael Ethiopian Jews0.1230122See
ISRIsrael Argentina Jews0.12264307See
DEUGermany pop 80.122439689See
USAUSA San Diego22.20.1220496See
DEUGermany pop 60.12148862See
MARMorocco Nador Metalsa0.121099See
USAUSA Caucasian pop 50.1210268See
TUNTunisia pop 30.1210104See
POLPoland Wielkopolska Region0.121099See
RUSRussia Northwest Slavic0.1200200See
USAUSA San Francisco Caucasian0.1200220See
MNGMongolia Khalkha0.1200200See
FRAFrance Rennes pop 30.1200200See
INDIndia Northeast Mech0.119063See
INDIndia Northeast UCBB21.30.1182296See
MNGMongolia Tsaatan0.1180144See
RUSRussia Siberia Lower Yenisey Ket0.118017See
DEUGermany DKMS - Netherlands minority0.11791374See
CHNChina, Xinjiang Uyghur Autonomous Region Hui23.50.117640See
BRABrazil North East Mixed0.1160205See
IRNIran Fars Parsi0.116073See
RUSRussia Arkhangelsk Pomor0.115063See
RUSRussia Karelia0.11471075See
USAUSA NMDP Middle Eastern or North Coast of Africa0.114670890See
THAThailand Bangkok pop 30.1120187See
BRABrazil South Caucasian0.111173See
BRABrazil Mato Grosso do Sul0.1110203See
DEUGermany DKMS - Romania minority0.11101234See
GRCGreece Crete0.1110135See
THAThailand Bangkok pop 20.110050See
USAUSA Caucasian Houston19.20.1090194See
AREUnited Arab Emirates Pop 10.1090570See
USAUSA NMDP Hispanic South or Central American0.1090146714See
GRCCretan Islanders0.1089124See
IRNIran Tabriz Azeris0.108297See
USAUSA NMDP American Indian South or Central America0.10805926See
NLDNetherlands Leiden0.10701305See
ESPSpain Andalusia Romani0.107099See
COLColombia Barranquilla0.1060188See
DEUGermany DKMS - Croatia minority0.10572057See
ITAItaly Rome21.00.1050100See
USAUSA Hispanic pop 20.10461999See
RUSRussia Siberia Dudinka Nganasan0.104024See
DEUGermany DKMS - Bosnia and Herzegovina minority0.10361028See
RUSRussia Tuva pop 20.1030169See
USAUSA Minnesota Olmsted0.1030339See
USAUSA NMDP African American pop 20.1011416581See
USAUSA NMDP North American Amerindian0.100635791See
BRABrazil Puyanawa18.70.1000150See
MNGMongolia Khalkha pop 20.1000202See
INDIndia North18.80.098885See
USAUSA NMDP African0.098328557See
CRICosta Rica African -Caribbean (G)19.60.0980102See
DEUGermany DKMS - China minority0.09791282See
HRVCroatia pop 40.09784000See
USAUSA African American pop 40.09772411See
ZAFSouth Africa Worcester19.00.0970159See
CHLChile Santiago0.0970920See
USAUSA NMDP Mexican or Chicano0.0961261235See
RUSRussia Tuva0.0960190See
ZAFSouth Africa Caucasians0.0960102See
USAUSA African American pop 70.0960193See
USAUSA NMDP Caribean Black0.095933328See
DEUGermany DKMS - Turkey minority0.09594856See
CHNChina Beijing Shijiazhuang Tianjian Han0.0950618See
BRABrazil Southeast Mixed Race19.00.095042See
IRNIran pop 20.0950120See
FRAFrance West18.00.0944100See
ISRIsrael Druze0.09415914See
GEOGeorgia Svaneti Region Svan0.094080See
USAUSA Colorado Univ Cord Blood Bank Hispanic0.09401058See
COLColombia Bogotá Cord Blood17.80.09401463See
NLDNetherlands UMCU15.60.093864See
USAUSA Southern California Mestizo17.80.093373See
ISRIsrael Iraq Jews0.093213270See
INDIndia North pop 20.093072See
LBNLebanon Niha el Shouff0.093061See
ARGArgentina Gran Chaco Western Toba Pilaga0.093019See
MYSMalaysia Peninsular Malay17.30.0925951See
CHLChile Mapuche0.092366See
DEUGermany Essen16.70.0920174See
STPSao Tome Island Forro0.091066See
CHNChina, Xinjiang Uyghur Autonomous Region Kazakh18.20.090952See
IDNIndonesia Singaporean0.090050See
IRNIran pop 30.0900100See
IRNIran Kurd0.0900100See
TURTurkey pop 10.0900250See
RUSRussia Siberia Sulamai Ket0.090022See
ISRIsrael Iran Jews0.08958153See
MEXMexico Nuevo Leon Mestizo17.50.089040See
USAUSA Colorado Univ Cord Blood Bank Asian0.0890100See
ISRIsrael Iranian Jews0.0880101See
ISRIsrael Arab pop 20.087312301See
IDNIndonesia Java0.086058See
CRICosta Rica Guanacaste Mestizo (G)15.40.0860110See
USAUSA Colorado Univ Cord Blood Bank African American0.0860261See
MEXMexico Chihuahua Chihuahua City Pop 217.00.085288See
RUSRussia Sakhalin Island Nivkhi0.085053See
MEXMexico Mexico City Mestizo population0.0839143See
DEUGermany DKMS - Greece minority0.08371894See
SGPSingapore Riau Malay0.0830132See
ISRIsrael Kavkazi Jews0.08292840See
USAUSA Mexican American Mestizo pop 30.0820116See
USAUSA Asian pop 20.08201772See
MEXMexico Mexico City Tlalpan16.10.0803330See
TZATanzania Maasai14.70.0780336See
SDNSudan Mixed15.00.0780200See
MNGMongolia Oold0.0770104See
LBNLebanon pop 20.0770191See
FRAFrance Southeast14.60.0760130See
USAUSA NMDP Alaska Native or Aleut0.07601376See
VNMVietnam Hanoi Kinh pop 20.0760170See
BRABrazil Mixed0.0750108See
IDNIndonesia Moluccan Islands0.075024See
KORSouth Korea pop 414.20.0737211See
NICNicaragua Managua13.80.0734339See
ECUEcuadorean Amerindians0.073375See
MKDMacedonia pop 10.0730158See
MEXMexico Highlands Mestizos14.40.0720160See
KORSouth Korea pop 30.0720485See
CHNChina Marrow Donor Registry0.0720600See
CODCongo Kinshasa Bantu13.30.072090See
USAUSA NMDP Korean0.071577584See
COLColombia San Basilio de Palenque0.071042See
MEXMexico Mexico City Mestizo pop 20.0705234See
KORSouth Korea pop 213.00.0700207See
KENKenya, Nyanza Province, Luo tribe13.00.0700100See
CHNChina Wuhan14.10.0700121See
MYSMalaysia Champa13.80.069029See
INDIndia Andhra Pradesh Golla0.0690111See
USAUSA South Texas Hispanic0.0690194See
NICNicaragua Mestizo (G)12.30.0680155See
MEXMexico Mexico City Mestizo pop 30.0680256See
KORSouth Korea pop 100.06804128See
KORSouth Korea pop 110.0670149See
IRNIran Kurd pop 20.067060See
COLColombia Sierra Nevada de Santa Marta Ijka pop 20.067030See
THAThailand Kamphaeng Phet0.067097See
CHNChina Hubei Han13.40.06693732See
IRNIran Saqqez-Baneh Kurds0.066760See
GRCGreece pop 813.30.066383See
GRCGreece pop212.80.0660120See
GABGabon Haut-Ogooue Dienga0.0660167See
KORSouth Korea pop 60.0640800See
MKDMacedonia pop 30.0640172See
USAUSA NMDP Vietnamese0.063943540See
USAUSA African American Bethesda12.60.0630187See
GEOGeorgia Caucasus Tbilisi0.0630119See
GNQEquatorial Guinea Bioko Island Bubi0.0630100See
CHNChina, Xinjiang Uyghur Autonomous Region Han12.50.062570See
CHNChina Yunnan Province Han pop 20.0620129See
CRICosta Rica and Panama Mestizo0.060056See
IRNIran Azeri0.0600100See
GRCGreece pop 60.0599242See
USAUSA NMDP Hawaiian or other Pacific Islander0.059611499See
CRICosta Rica Central Valley Mestizo (G)11.80.0590221See
ARGArgentina Rio Negro Mapuche0.059034See
MNGMongolia Hoton0.059085See
MNGMongolia Tarialan Khoton0.059085See
KORSouth Korea pop 10.0590324See
CHNChina Zhejiang Han pop 20.0582833See
COLColombia North Wiwa El Encanto0.057752See
CHNChina Canton Han0.0570264See
CODCongo Kinshasa expatriates living in Belgium11.40.057075See
RWARwanda Kigali Hutu and Tutsi0.0570281See
RUSRussia Siberia Eskimo0.056070See
GMBGambia pop 310.50.0557939See
SWESweden Southern Sami0.0550130See
GHAGhana Accre Asutuare Akan0.0540429See
USAUSA NMDP Chinese0.053199672See
NZLNew Zealand Maori0.0530200See
FINFinland pop20.0530150See
ARGArgentina Rosario Toba10.50.052086See
CHLChile Santiago Mixed10.00.051370See
USAUSA Hawaii0.051039See
CHNChina Harbin Korean0.0500201See
COLColombia West Cauca0.050020See
ARMArmenia combined Regions0.0500100See
MEXMexico Guanajuato and Jalisco Mestizo9.90.0500101See
ISRIsrael Georgia Jews0.04984471See
MNGMongolia Ulaanbaatar Khalkha0.049041See
VNMVietnam Hanoi Kinh0.0490103See
USAUSA South Dakota Sioux0.0470101See
RUSRussia Siberia Irkutsk Tofalar0.047043See
USAUSA NMDP Filipino0.046750614See
ZWEZimbabwe Harare Shona0.0460230See
CRICosta Rica Amerindians (G)8.40.0460125See
TWNTaiwan pop 20.0450364See
RUSRussia Tuva pop30.045044See
LBNLebanon Kafar Zubian0.043094See
HRVCroatia Krk Island Dubasnica0.043023See
RUSRussia Siberia Ulchi0.041073See
RUSRussia Siberia Khabarovsk Evenki0.040025See
MYSMalaysia Patani8.00.040025See
AUSAustralia Cape York Peninsula Aborigine0.0400103See
HKGHong Kong Chinese cord blood registry0.03913892See
HRVCroatia Krk Island0.0380212See
NZLNew Zealand Maori with Admixed History6.70.0380105See
HKGHong Kong Chinese BMDR0.03777595See
MYSMalaysia Mandailing7.40.037027See
ITAItaly North Pavia0.037081See
HRVCroatia Krk Island Vrbnik0.036028See
MEXMexico Veracruz Xalapa7.10.035784See
ARGArgentina Mapuche0.035048See
COLColombia Providencia Island African0.033030See
MEXMexico Sonora Seri0.030034See
MYSMalaysia Sarawak Bidayuh0.030050See
IRNIran Baloch0.0300100See
RUSRussia Siberia Polygus Evenk0.030035See
USAUSA Philippines0.0290105See
TWNTaiwan Tzu Chi Morrow Donor Registry0.028146682See
TWNTaiwan Han Chinese0.0280504See
TWNTaiwan Hakka5.50.027055See
ARGArgentina Salta Wichi pop 25.30.026019See
BORBorneo Bandjarmasin0.024021See
BOLBolivia/Peru Quechua NA-DHS_12 (G)4.80.023821See
MYSMalaysia Peninsular Chinese4.60.0232194See
TWNTaiwan Tzu Chi Cord Blood Bank0.0230710See
WSMSamoa West0.023022See
RUSRussia Tuva Todja0.022022See
ARGArgentina Chubut Tehuelche0.022023See
MYSMalaysia Jelebu Temuan0.021025See
MYSMalaysia Sarawak Iban0.020051See
RUSRussia Siberia Gvaysugi Udege0.020025See
RUSRussia Siberia NW of Sakhalin Island Nivkh0.020032See
TWNTaiwan Siraya3.90.020051See
USAUSA South Dakota Lakota Sioux0.0200302See
ARGArgentina Chiriguano3.60.018054See
BRABrazil Guarani Nandeva0.017086See
COLColombia Northwest Tule0.017029See
MEXMexico Oaxaca Zapotec0.017090See
STPSao Tome Island Angolar0.016032See
TWNTaiwan pop10.0150539See
NCLNew Caledonia0.015065See
CHNChina Yunnan Province Han0.0150101See
ARGArgentina Gran Chaco Eastern Toba0.0150135See
MEXMexico Tixcacaltuyub Maya0.014967See
BOLBolivia Quechua0.014569See
JORJordan Amman0.0140146See
ITAItaly Sardinia pop22.20.01101129See
ARGArgentina Gran Chaco Mataco Wichi0.011049See
SENSenegal Dakar2.20.0110112See
TWNTaiwan Tzu Chi Morrow Donor Registry Aborigine0.0107233See
COLColombia North Chimila Amerindians0.010647See
COKCook Islands0.010050See
TWNTaiwan Minnan pop 12.00.0100102See
THAThailand North Dai Lue0.010096See
RUSRussia Siberia Chukotka Peninsula Chukchi0.010059See
WSMSamoa pop20.010050See
USAUSA NMDP Japanese0.009424582See
MEXMexico Sinaloa Capomos Mayo Yoremes0.008360See
CHNChina Southwest Dai0.0080124See
MEXMexico Mazatecan0.007089See
SWESweden Northern Sami0.0070154See
MEXMexico Nahua/Aztec Santo Domingo Ocotitlan0.006873See
BOLBolivia La Paz Aymaras0.006087See
PNGPapua New Guinea Highland0.006094See
VNMVietnam HoaBinh Muong0.006083See
PERPeru Titikaka Lake Uro0.0050105See
PERPeru Titikaka Lake Uros0.0050105See
CHNChina Yunnan Bulang0.0040116See
CHNChina Yunnan Province Naxi0.0040118See
JPNJapan South0.80.0040125See
JPNJapan pop 170.00363078See
JPNJapan pop 160.003418604See
JPNJapan pop 40.60.0030525See
JPNJapan Kyoto and Osaka0.0030165See
JPNJapan Central0.0030371See
CHNChina Yunnan Hani0.0030150See
MEXMexico Chiapas Lacandon Mayans0.0023218See
JPNJapan pop 30.00201018See
BRABrazil Kaingang0.0020235See
BRABrazil Central Plateau Xavante0.000074See
BRABrazil Vale do Ribeira Quilombos0.10.0000144See
CHLChile Huilliche0.000040See
ARGArgentina Salta Wichi0.000024See
ARGArgentina Kolla0.000061See
FJIFiji Viti Levu Island0.000057See
JPNJapan Hyogo Osaka and Nagano0.0000195See
JPNJapan pop 110.00.000062See
MEXMexico Oaxaca Mixtec0.0000103See
IDNIndonesia Nusa Tenggara Islands0.000049See
PHLPhilippines Ivatan0.00.000050See
PNGPapua New Guinea Eastern Highlands Goroka Asaro0.000057See
PNGPapua New Guinea Madang0.000065See
PNGPapua New Guinea East New Britain Rabaul0.000060See
PNGPapua New Guinea Lowland Roro0.000026See
PNGPapua New Guinea Trobriand Island0.000081See
PNGPapua New Guinea Lowland0.000047See
PNGPapua New Guinea Lowland Wosera0.000079See
PNGPapua New Guinea East New Britain Tolai0.000048See
PNGPapua New Guinea Highland pop20.000028See
PRYParaguay Lengua0.000017See
RUSRussia Siberia Chukotka Peninsula Eskimo0.000080See
RUSRussia Siberia North East Kamchatka Koryak0.000092See
RUSRussia Siberia Chukchi0.000071See
RUSRussia Siberia Negidal0.000035See
TWNTaiwan Atayal0.00.0000106See
TWNTaiwan Taroko0.00.000055See
TWNTaiwan Saisiat0.00.000051See
TWNTaiwan Bunun0.00.0000101See
TWNTaiwan Pazeh0.00.000055See
TWNTaiwan Thao0.00.000030See
TWNTaiwan Aborigine pop 20.000048See
TWNTaiwan Tsou0.00.000051See
TWNTaiwan Rukai0.00.000050See
TWNTaiwan Paiwan0.00.000051See
TWNTaiwan Ami0.00.000098See
TWNTaiwan Puyuma0.00.000050See
TWNTaiwan Tao0.00.000050See
USAUSA Alaska Yupik0.0000252See

Frequency data at lower resolution for this allele can be found in links below

Allele  Number of Populations 


* Allele Frequency: Total number of copies of the allele in the population sample (Alleles / 2n) in decimal format.
   Important: This field has been expanded to four decimals to better represent frequencies of large datasets (e.g. where sample size > 1000 individuals)
* Phenotype Frequency: Percentage of individuals who have the allele or gene (Individuals / n).
* Allele Frequencies shown in green were calculated from Phenotype Frequencies assuming Hardy-Weinberg proportions.

¹ IMGT/HLA Database - For more details of the allele.
² Distribution - Graphical distribution of the allele.
³ Haplotype Association - Find HLA haplotypes with this allele.
ª Notes - See notes for ambiguous combinations of alleles.


Allele frequency net database (AFND) 2020 update: gold-standard data classification, open access genotype data and new query tools
Gonzalez-Galarza FF, McCabe A, Santos EJ, Jones J, Takeshita LY, Ortega-Rivera ND, Del Cid-Pavon GM, Ramsbottom K, Ghattaoraya GS, Alfirevic A, Middleton D and Jones AR Nucleic Acid Research 2020, 48:D783-8.
Liverpool, U.K.

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