Allele Frequencies in World Populations

HLA Database » Allele Report

The list below shows all populations in AFND that contains the allele. If an allele has an entry with a lower resolution this will be shown at the end.



Allele reported 334 time(s) and present in 284 population(s).

Population Phenotype
Frequency (%)
Distribution² Haplotype³
SWESweden Northern Sami0.1980154See
FINFinland pop20.1230150See
RUSRussia Siberia Lower Yenisey Ket0.118017See
RUSRussia Siberia Polygus Evenk0.100035See
ESPSpain Tenerife Island0.088083See
COLColombia San Basilio de Palenque0.083042See
RUSRussia Chuvash0.079082See
COLColombia Barranquilla0.0745188See
RUSRussia Siberia Sulamai Ket0.070022See
RUSRussia Siberia Irkutsk Tofalar0.070043See
MNGMongolia Tsaatan0.0700144See
RUSRussia Bering Island Aleuts0.0673104See
SWESweden Southern Sami0.0640130See
RUSRussia Siberia Khabarovsk Evenki0.060025See
IRNIran Yazd Zoroastrian0.054065See
PRTPortugal Center0.050050See
PRTPortugal Azores Terceira Island9.60.0482130See
RUSRussia Karelia0.04511075See
RUSRussia Tuva Todja0.045022See
IRNIran Yazd0.044656See
GEOGeorgia Svaneti Region Svan0.044080See
PRTAzores Terceira Island0.0430130See
LBNLebanon Niha el Shouff0.042061See
RUSRussia Siberia Khanty Mansi0.037068See
SVNSlovenia pop 27.10.0361140See
PRTAzores Central Islands0.036059See
ITAItaly North pop 37.20.036097See
TUNTunisia Jerba Berber0.036055See
DEUGermany DKMS - Austria minority0.03531698See
USAUSA Caucasian Houston7.00.0350194See
BRABrazil South Caucasian0.034773See
DEUGermany DKMS - Bosnia and Herzegovina minority0.03451028See
CZECzech Republic0.0330106See
PRTPortugal North0.033046See
RUSRussia Belgorod region6.50.0327153See
USAUSA Minnesota Olmsted0.0320339See
IRNIran Gorgan0.031064See
IRNIran Tabriz Azeris0.030997See
FRAFrance West6.00.0304100See
CHNChina, Xinjiang Uyghur Autonomous Region Kazakh6.10.030352See
IRNIran pop 30.0300100See
MNGMongolia Khalkha pop 20.0300202See
USAUSA San Francisco Caucasian0.0300220See
POLPoland DKMS0.029720653See
HRVCroatia pop 40.02944000See
CHNChina, Xinjiang Uyghur Autonomous Region Hui5.90.029440See
CZECzech Republic NMDR0.02915099See
MNGMongolia Oold0.0290104See
BRABrazil Paraná Caucasian5.50.0289641See
DEUGermany DKMS - German donors0.02853456066See
DEUGermany pop 60.02868862See
USAUSA Caucasian pop 40.02791070See
DEUGermany pop 35.40.0273111See
USAUSA Eastern European0.0270558See
DEUGermany pop 80.026639689See
DEUGermany DKMS - Croatia minority0.02632057See
DEUGermany Essen5.20.0260174See
NLDNetherlands Leiden0.02601305See
PRTMadeira pop 20.0260173See
PRTAzores Oriental Islands0.026043See
ESPSpain Gipuzkoa Basque0.0260100See
DEUGermany DKMS - France minority0.02561406See
FRAFrance Rennes0.0250200See
IRNIran pop 20.0250120See
BRABrazil Mixed0.0250108See
CHNChina, Xinjiang Uyghur Autonomous Region Han5.00.025070See
ITAItaly Bergamo4.90.0250101See
ISRIsrael Ashkenazi Jews0.025080See
USAUSA Colorado Univ Cord Blood Bank Caucasian0.02503830See
FRAFrance French Bone Marrow Donor Registry0.024642623See
COLColombia Bogota and Medellin Mestizo0.024065See
BRABrazil Southeast Mixed Race4.80.024042See
ESPSpain Catalonia Girona0.024088See
USAUSA Caucasian pop 50.0240268See
DEUGermany DKMS - Portugal minority0.02381176See
DEUGermany DKMS - Netherlands minority0.02371374See
USAUSA NMDP European Caucasian0.02321242890See
USAUSA Caucasian Pittsburgh4.60.0230177See
RUSRussia Northwest Slavic0.0230200See
RUSRussia Tuva0.0230190See
RUSRussia Tuva pop30.023044See
DEUGermany DKMS - Romania minority0.02231234See
ESPSpain (Catalunya, Navarra, Extremadura, Aaragón, Cantabria,4.40.02194335See
USAUSA Caucasian Bethesda4.20.0210307See
RUSRussia Siberia Dudinka Nganasan0.021024See
ITAItaly pop 50.0210975See
DEUGermany DKMS - Spain minority0.02031107See
CZECzech Republic pop 24.00.020299See
MNGMongolia Khalkha0.0200200See
RUSRussia Siberia Kushun Buryat0.020025See
RUSRussia Siberia Chukotka Peninsula Chukchi0.020059See
PRTPortugal South0.020049See
CHNChina Harbin Manchu pop 20.020050See
FRAFrance Rennes pop 30.0200200See
ENGEngland pop 64.00.0200177See
GRCGreece pop 40.020098See
FRAFrance Southeast3.80.0190130See
BRABrazil Southeast Caucasian3.90.0190103See
ESPSpain Barcelona3.80.0190941See
LBNLebanon pop 20.0190191See
MKDMacedonia pop 10.0190158See
TUNTunisia Matmata Berber0.019081See
ENGEngland Bedfordshire3.70.0186354See
CHNChina Urumqi Uyghur3.50.018057See
ISRIsrael USSR Jews0.017645681See
DEUGermany DKMS - United Kingdom minority0.01731043See
NIRIreland Northern3.40.01701000See
IRNIran Kurd pop 20.017060See
CHNChina Yunnan Province Naxi0.0170118See
COLColombia Sierra Nevada de Santa Marta Ijka pop 20.017030See
BRABrazil North East Mixed0.0170205See
MKDMacedonia pop 30.0170172See
RUSRussia Transbaikal Territory Buryats3.00.0170150See
USAUSA NMDP American Indian South or Central America0.01705926See
IRNIran Saqqez-Baneh Kurds0.016760See
RUSRussia Tuva pop 20.0160169See
USAUSA South Dakota Sioux0.0160101See
USAUSA NMDP North American Amerindian0.015635791See
USAUSA NMDP Caribean Hispanic0.0151115374See
STPSao Tome Island Forro0.015066See
POLPoland Wielkopolska Region0.015099See
ITAItaly Rome3.00.0150100See
ISRIsrael USA Jews0.01456058See
ARGArgentina Buenos Aires2.90.0140466See
NZLNew Zealand Maori with Admixed History2.90.0140105See
MEXMexico Mexico City Mestizo pop 30.0140256See
RUSRussia Siberia Negidal0.014035See
TURTurkey pop 10.0140250See
DEUGermany DKMS - Italy minority0.01321159See
ENGEngland North West2.70.0130298See
BRABrazil Puyanawa2.70.0130150See
MEXMexico Highlands Mestizos2.50.0130160See
NICNicaragua Mestizo (G)2.60.0130155See
USAUSA NMDP Caribean Indian0.013014339See
USAUSA San Diego2.60.0130496See
GEOGeorgia Caucasus Tbilisi0.0126119See
USAUSA NMDP Hispanic South or Central American0.0120146714See
USAUSA NMDP Alaska Native or Aleut0.01201376See
GRCGreece pop22.40.0120120See
CHNChina Urumqi Kazak0.012042See
MEXMexico Nuevo Leon Mestizo2.50.012040See
MEXMexico Mayan pop 20.0120163See
MKDMacedonia pop 20.012080See
ITAItaly Central0.0120380See
ESPSpain Murcia0.0120173See
MEXMexico Veracruz Xalapa2.40.011984See
CHLChile Santiago0.0116920See
INDIndia North2.30.011585See
ISRIsrael Morocco Jews0.011236718See
ISRIsrael Ashkenazi Jews pop 30.01104625See
ZAFSouth Africa Caucasians0.0110102See
DEUGermany DKMS - Greece minority0.01111894See
USAUSA Philadelphia Caucasian2.10.0110141See
ESPSpain Pas Valley0.011088See
CHNChina, Xinjiang Uyghur Autonomous Region Uyghur2.20.010971See
USAUSA NMDP Middle Eastern or North Coast of Africa0.010370890See
DEUGermany DKMS - Turkey minority0.01024856See
CHLChile Santiago Mixed2.00.010070See
BRABrazil Ticuna0.010050See
BRABrazil Mato Grosso do Sul0.0100203See
DZAAlgeria pop 22.00.0100106See
DZAAlgeria Oran0.0100100See
SCOScotland Orkney1.90.010099See
TUNTunisia pop 30.0100104See
USAUSA Colorado Univ Cord Blood Bank Hispanic0.01001058See
ISRIsrael Poland Jews0.009713871See
COLColombia Bogotá Cord Blood1.90.00961463See
MEXMexico Chiapas Lacandon Mayans0.0092218See
RUSRussia Siberia Eskimo0.009070See
INDIndia North pop 20.009072See
USAUSA NMDP Mexican or Chicano0.0088261235See
MEXMexico Sinaloa Capomos Mayo Yoremes0.008360See
USAUSA Hispanic pop 20.00831999See
NCLNew Caledonia0.008065See
RUSRussia Siberia Chukchi0.008071See
IRLIreland South1.60.0080250See
CHNChina Yunnan Province Han pop 20.0080129See
BOLBolivia Quechua0.007269See
ISRIsrael Tunisia Jews0.00709070See
CUBCuba Mixed0.007078See
MEXMexico Mexico City Mestizo population0.0070143See
ISRIsrael Yemenite Jews0.007076See
ECUEcuadorean Amerindians0.006775See
GRCGreece pop 60.0062242See
MEXMexico Mexico City Tlalpan1.20.0061330See
MNGMongolia Hoton0.006085See
NICNicaragua Managua1.20.0060339See
PERPeru Lamas City Lama0.006083See
ESPSpain North Cantabria0.006083See
GNQEquatorial Guinea Bioko Island Bubi0.0060100See
GRCGreece pop 81.20.006083See
ARGArgentina Rosario Toba1.20.006086See
USAUSA Colorado Univ Cord Blood Bank African American0.0060261See
MEXMexico Chihuahua Chihuahua City Pop 21.10.005788See
MARMorocco Nador Metalsa0.005099See
MARMorocco Settat Chaouya0.005098See
MARMorocco Atlantic Coast Chaouya0.005098See
ISRIsrael Arab0.0050109See
ISRIsrael Moroccan Jews0.0050113See
ESPSpain Andalusia Romani0.005099See
PERPeru Titikaka Lake Uro0.0050105See
PERPeru Titikaka Lake Uros0.0050105See
HRVCroatia Krk Island0.0050212See
CHNChina Lijiang Naxi0.0050100See
INDIndia Delhi0.0050112See
INDIndia Andhra Pradesh Golla0.0050111See
IRNIran Azeri0.0050100See
USAUSA Philippines0.0050105See
INDIndia North UCBB1.00.00505849See
CRICosta Rica Central Valley Mestizo (G)0.90.0045221See
USAUSA African American pop 40.00462411See
USAUSA Asian pop 20.00451772See
USAUSA San Antonio Caucasian0.0045222See
INDIndia Central UCBB0.80.00424204See
ISRIsrael Ethiopian Jews0.0040122See
GTMGuatemala Mayan0.0040132See
CRICosta Rica Amerindians (G)0.80.0040125See
CHNChina Wuhan0.80.0040121See
USAUSA NMDP Hawaiian or other Pacific Islander0.003811499See
USAUSA NMDP African American pop 20.0037416581See
INDIndia West UCBB0.70.00355829See
USAUSA NMDP South Asian Indian0.0032185391See
CHNChina Yunnan Hani0.0030150See
CHNChina Harbin Manchu0.0030172See
NZLNew Zealand Maori0.0030200See
ISRIsrael Kavkazi Jews0.00302840See
USAUSA NMDP Caribean Black0.002933328See
USAUSA NMDP Southeast Asian0.002827978See
MYSMalaysia Peninsular Malay0.50.0026951See
MYSMalaysia Peninsular Chinese0.50.0026194See
ISRIsrael Arab pop 20.002412301See
MEXMexico Mexico City Mestizo pop 20.0021234See
INDIndia East UCBB0.40.00212403See
USAUSA NMDP African0.002028557See
USAUSA South Texas Hispanic0.0020194See
USAUSA South Dakota Lakota Sioux0.0020302See
JPNJapan pop 20.0020916See
ISRIsrael Argentina Jews0.00204307See
MYSMalaysia Peninsular Indian0.40.0018271See
CHNChina Jiangsu Province Han0.0018334See
ISRIsrael Bukhara Jews0.00172317See
INDIndia Northeast UCBB0.30.0017296See
INDIndia South UCBB0.30.001511446See
USAUSA NMDP Filipino0.001150614See
GMBGambia pop 30.10.0011939See
ISRIsrael Iran Jews0.00108153See
LKASri Lanka Colombo0.30.0010714See
TWNTaiwan pop 20.0010364See
TWNTaiwan Han Chinese0.0010504See
CHNChina Beijing Shijiazhuang Tianjian Han0.0010618See
USAUSA NMDP Japanese0.000824582See
DEUGermany DKMS - China minority0.00081282See
CHNChina Zhejiang Han pop 20.0006833See
ISRIsrael Georgia Jews0.00064471See
KORSouth Korea pop 100.00054128See
USAUSA NMDP Korean0.000477584See
INDIndia Tamil Nadu0.00042492See
CHNChina Hubei Han0.10.00043732See
ISRIsrael Druze0.00035914See
USAUSA NMDP Vietnamese0.000343540See
HKGHong Kong Chinese BMDR0.00037595See
USAUSA NMDP Chinese0.000299672See
HKGHong Kong Chinese cord blood registry0.00013892See
ISRIsrael Ethiopia Jews0.00015928See
ISRIsrael Iraq Jews0.000013270See
ISRIsrael YemenJews0.000015542See
IRNIran Kurd0.0000100See
IDNIndonesia Java Yogyakarta Region0.000062See
IRNIran Fars Parsi0.000073See
FJIFiji Viti Levu Island0.000057See
CANCanada British Columbia Athabaskan0.000062See
CANCanada British Columbia Penutian0.000026See
CAFCentral African Republic Aka Pygmy0.00.000093See
BRABrazil Central Plateau Xavante0.000074See
BRABrazil Guarani M bya0.000093See
BRABrazil Guarani Nandeva0.000086See
BRABrazil Kaingang0.0000235See
BRABrazil Vale do Ribeira Quilombos0.00.0000144See
ARGArgentina Rio Negro Mapuche0.000034See
ARGArgentina Chubut Tehuelche0.000023See
ARGArgentina Salta Wichi0.000024See
ARGArgentina Gran Chaco Eastern Toba0.0000135See
ARGArgentina Gran Chaco Mataco Wichi0.000049See
ARGArgentina Gran Chaco Western Toba Pilaga0.000019See
CHNChina Harbin Korean0.0000201See
CHNChina Urumqi Han0.000059See
CZECzech Republic Romani0.00.000034See
CODCongo Kinshasa Bantu0.00.000090See
COKCook Islands Rarotonga0.000078See
COKCook Islands0.000050See
ISRIsrael Ashkenazi Jews pop 20.0000132See
ISRIsrael Libyan Jews0.0000119See
ISRIsrael Iranian Jews0.0000101See
LBNLebanon Kafar Zubian0.000094See
JPNJapan Hyogo Osaka and Nagano0.0000195See
KORSouth Korea pop 30.0000485See
KORSouth Korea pop 20.00.0000207See
LBNLebanon Yuhmur0.000082See
RUSRussia Siberia Ulchi0.000073See
STPSao Tome Island Angolar0.000032See
WSMSamoa pop20.000050See
WSMWestern Samoa and Tokelau0.000051See
RUSRussia Siberia Chukotka Peninsula Eskimo0.000080See
RUSRussia Siberia North East Kamchatka Koryak0.000092See
RUSRussia Siberia Gvaysugi Udege0.000025See
RUSRussia Siberia NW of Sakhalin Island Nivkh0.000032See
PNGPapua New Guinea Eastern Highlands Goroka Asaro0.000057See
PNGPapua New Guinea Madang0.000065See
PNGPapua New Guinea East New Britain Rabaul0.000060See
PRYParaguay Lengua0.000017See
USAUSA Alaska Yupik0.0000252See
USAUSA Colorado Univ Cord Blood Bank Asian0.0000100See
USAUSA African American Bethesda0.00.0000187See
TUNTunisia Gabes Arab0.000096See

Frequency data at lower resolution for this allele can be found in links below

Allele  Number of Populations 


* Allele Frequency: Total number of copies of the allele in the population sample (Alleles / 2n) in decimal format.
   Important: This field has been expanded to four decimals to better represent frequencies of large datasets (e.g. where sample size > 1000 individuals)
* Phenotype Frequency: Percentage of individuals who have the allele or gene (Individuals / n).
* Allele Frequencies shown in green were calculated from Phenotype Frequencies assuming Hardy-Weinberg proportions.

¹ IMGT/HLA Database - For more details of the allele.
² Distribution - Graphical distribution of the allele.
³ Haplotype Association - Find HLA haplotypes with this allele.
ª Notes - See notes for ambiguous combinations of alleles.


Allele frequency net database (AFND) 2020 update: gold-standard data classification, open access genotype data and new query tools
Gonzalez-Galarza FF, McCabe A, Santos EJ, Jones J, Takeshita LY, Ortega-Rivera ND, Del Cid-Pavon GM, Ramsbottom K, Ghattaoraya GS, Alfirevic A, Middleton D and Jones AR Nucleic Acid Research 2020, 48:D783-8.
Liverpool, U.K.

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