Allele Frequencies in World Populations

HLA Database » Allele Report

The list below shows all populations in AFND that contains the allele. If an allele has an entry with a lower resolution this will be shown at the end.



Allele reported 305 time(s) and present in 250 population(s).

Population Phenotype
Frequency (%)
Distribution² Haplotype³
PNGPapua New Guinea Trobriand Island0.321081See
AUSAustralia Yuendumu Aborigine0.2650191See
PNGPapua New Guinea Dorogori0.254059See
PNGPapua New Guinea Wuroi0.221034See
PNGPapua New Guinea Iamega0.209079See
PNGPapua New Guinea South Gidra0.2080192See
PNGPapua New Guinea Rual0.200050See
PNGPapua New Guinea Podare0.198043See
NZLNew Zealand Maori with Full Ancestry30.40.196046See
PNGPapua New Guinea Kapal0.185065See
PNGPapua New Guinea Abam0.175063See
PNGPapua New Guinea Ume0.167090See
PNGPapua New Guinea Wonie0.157051See
PNGPapua New Guinea Kuru0.141046See
PNGPapua New Guinea Wipim0.127055See
NZLNew Zealand Maori with Admixed History21.00.1240105See
WSMWestern Samoa and Tokelau0.098051See
PNGPapua New Guinea Eastern Highlands Goroka Asaro0.097057See
TWNTaiwan pop 20.0970364See
FJIFiji Viti Levu Island0.097057See
PNGPapua New Guinea Woigi0.096026See
PNGPapua New Guinea Lowland Roro0.096026See
NZLNew Zealand Polynesians with Full Ancestry14.30.095021See
JPNJapan pop 30.09401018See
JPNJapan pop 417.90.0940525See
JPNJapan pop 617.80.0933129See
NZLNew Zealand Polynesians with Admixed History14.80.093027See
JPNJapan South17.60.0922125See
KORSouth Korea pop 110.0910149See
CHNChina Zhejiang Han pop 20.0876833See
CHNChina, Xinjiang Uyghur Autonomous Region Han15.00.087570See
TWNTaiwan Han Chinese0.0860504See
JPNJapan pop 160.083218604See
TWNTaiwan Tzu Chi Morrow Donor Registry Aborigine0.0815233See
KORSouth Korea pop 415.60.0813211See
JPNJapan Central0.0810371See
TWNTaiwan Tzu Chi Morrow Donor Registry0.081046682See
JPNJapan pop 170.08013078See
KORSouth Korea pop 30.0800485See
CHNChina Hubei Han15.90.07943732See
KORSouth Korea pop 100.07874128See
CHNChina Jiangsu Province Han0.0784334See
JPNJapan Hyogo15.60.078032See
TWNTaiwan pop10.0780539See
NCLNew Caledonia0.077065See
USAUSA NMDP Korean0.076277584See
TWNTaiwan Tzu Chi Cord Blood Bank0.0760710See
JPNJapan Kyoto and Osaka0.0760165See
JPNJapan pop 20.0760916See
JPNJapan pop 1114.50.075362See
KORSouth Korea pop 215.00.0750207See
CHNChina Marrow Donor Registry0.0750600See
CHNChina Harbin Korean0.0750201See
USAUSA NMDP Japanese0.074424582See
JPNJapan Hokkaido Wajin14.10.073171See
KORSouth Korea pop 10.0730324See
USAUSA NMDP Hawaiian or other Pacific Islander0.072011499See
THAThailand Bangkok pop 20.070050See
MYSMalaysia Peninsular Chinese12.40.0696194See
KORSouth Korea pop 60.0690800See
HKGHong Kong Chinese cord blood registry0.06853892See
USAUSA NMDP Chinese0.068099672See
CHNChina Wuhan13.20.0660121See
DEUGermany DKMS - China minority0.06441282See
USAUSA Hawaii0.064039See
PNGPapua New Guinea Highland0.063094See
HKGHong Kong Chinese BMDR0.06207595See
JPNJapan Hyogo Osaka and Nagano0.0610195See
CHNChina Canton Han0.0590264See
CHNChina Urumqi Han0.059059See
CHNChina Jiangsu Han0.05803238See
COKCook Islands Rarotonga0.058078See
CHNChina Beijing and Xian0.0560171See
VNMVietnam Hanoi Kinh0.0540103See
PNGPapua New Guinea Lowland0.052047See
USAUSA Asian pop 20.05181772See
CHNChina Guangxi Region Maonan0.0510108See
PNGPapua New Guinea East New Britain Rabaul0.050060See
CHNChina, Xinjiang Uyghur Autonomous Region Kazakh9.10.045552See
JPNJapan Nagano8.80.045057See
CHNChina Beijing Shijiazhuang Tianjian Han0.0410618See
VNMVietnam Hanoi Kinh pop 20.0410170See
CHNChina Harbin Manchu pop 20.040050See
USAUSA NMDP Vietnamese0.039943540See
IDNIndonesia Moluccan Islands0.038024See
USAUSA Colorado Univ Cord Blood Bank Asian0.0360100See
CHNChina pop16.80.0350103See
CHNChina Hong Kong and Singapore0.0330135See
CHNChina Harbin Manchu0.0320172See
USAUSA NMDP Filipino0.030950614See
CHNChina Yunnan Province Han0.0300101See
CHNChina Yunnan Hani0.0300150See
IDNIndonesia Singaporean0.030050See
CHNChina, Xinjiang Uyghur Autonomous Region Hui5.90.029440See
RUSRussia Siberia Ulchi0.027073See
MNGMongolia Khalkha0.0250200See
MNGMongolia Khalkha pop 20.0250202See
CHNChina, Xinjiang Uyghur Autonomous Region Uyghur2.80.021771See
MNGMongolia Tsaatan0.0210144See
MYSMalaysia Sarawak Iban0.020051See
MYSMalaysia Patani4.00.020025See
PRTPortugal Center0.020050See
MYSMalaysia Peninsular Malay3.70.0189951See
MYSMalaysia Peninsular Indian3.70.0185271See
TUNTunisia Jerba Berber0.018055See
USAUSA NMDP Southeast Asian0.017827978See
RUSRussia Transbaikal Territory Buryats3.00.0170150See
GEOGeorgia Caucasus Tbilisi0.0168119See
CHNChina Xinjiang Province Uyghur0.016092See
ARMArmenia combined Regions0.0150100See
COLColombia Bogota and Medellin Mestizo0.015065See
IRNIran Azeri0.0150100See
PNGPapua New Guinea Madang0.015065See
USAUSA Southern California Mestizo2.70.013573See
LKASri Lanka Colombo2.50.0130714See
RUSRussia Northwest Slavic0.0130200See
GEOGeorgia Svaneti Region Svan0.013080See
IDNIndonesia Java Yogyakarta Region0.013062See
CHNChina Yunnan Bulang0.0130116See
INDIndia Tamil Nadu0.01222492See
IDNIndonesia Nusa Tenggara Islands0.012049See
BRABrazil Southeast Mixed Race2.40.012042See
MNGMongolia Tarialan Khoton0.012085See
MNGMongolia Ulaanbaatar Khalkha0.012041See
MNGMongolia Hoton0.012085See
RUSRussia Tuva pop30.011044See
ISRIsrael Moroccan Jews0.0110113See
DEUGermany DKMS - Turkey minority0.01074856See
INDIndia South UCBB2.00.010111446See
ITAItaly Bergamo1.90.0100101See
ESPSpain Andalusia0.010099See
CZECzech Republic0.0100106See
THAThailand North Dai Lue0.010096See
USAUSA Philippines0.0100105See
JPNJapan Hokkaido Ainu0.010050See
MNGMongolia Oold0.0100104See
AREUnited Arab Emirates Abu Dhabi0.009652See
IDNIndonesia Java0.009058See
MYSMalaysia Sabah Kadazan0.009057See
USAUSA San Diego1.60.0090496See
RUSRussia Sakhalin Island Nivkhi0.009053See
PRTAzores Central Islands0.009059See
RUSRussia Tuva0.0080190See
TURTurkey pop 10.0080250See
FRAFrance Southeast1.50.0080130See
DEUGermany DKMS - Greece minority0.00791894See
USAUSA NMDP South Asian Indian0.0071185391See
IDNIndonesia Java Western1.30.0070236See
FINFinland pop20.0070150See
BRABrazil Mato Grosso do Sul0.0070203See
BRABrazil South Caucasian0.006973See
TUNTunisia Matmata Berber0.006081See
BRABrazil North East Mixed0.0060205See
DEUGermany DKMS - Portugal minority0.00551176See
DZAAlgeria pop 21.00.0050106See
HRVCroatia Krk Island0.0050212See
ITAItaly Central0.0050380See
ARGArgentina Buenos Aires1.00.0050466See
CZECzech Republic pop 21.00.005099See
TUNTunisia pop 30.0050104See
PRTPortugal Azores Terceira Island0.90.0044130See
PRTAzores Terceira Island0.0040130See
CHNChina Southwest Dai0.0040124See
AREUnited Arab Emirates Pop 10.0040570See
IRLIreland South0.80.0040250See
GRCCretan Islanders0.0040124See
GRCGreece pop20.80.0040120See
ESPSpain Murcia0.0040173See
USAUSA Caucasian pop 50.0040268See
BRABrazil Paraná Caucasian0.80.0039641See
ISRIsrael Georgia Jews0.00324471See
ITAItaly pop 50.0030975See
DEUGermany Essen0.60.0030174See
SWESweden Northern Sami0.0030154See
USAUSA Eastern European0.0030558See
USAUSA NMDP American Indian South or Central America0.00305926See
USAUSA Colorado Univ Cord Blood Bank Caucasian0.00303830See
USAUSA Caucasian Houston0.60.0030194See
ZAFSouth Africa Worcester1.00.0030159See
DEUGermany pop 80.002939689See
INDIndia Central UCBB0.60.00294204See
DEUGermany DKMS - United Kingdom minority0.00291043See
DEUGermany DKMS - Austria minority0.00271698See
USAUSA NMDP Mexican or Chicano0.0027261235See
DEUGermany DKMS - France minority0.00251406See
DEUGermany DKMS - German donors0.00243456066See
USAUSA NMDP Middle Eastern or North Coast of Africa0.002470890See
USAUSA NMDP European Caucasian0.00241242890See
INDIndia North UCBB0.50.00235849See
USAUSA San Antonio Caucasian0.0023222See
MEXMexico Mexico City Mestizo pop 20.0021234See
DEUGermany DKMS - Italy minority0.00221159See
DEUGermany DKMS - Netherlands minority0.00221374See
SAUSaudi Arabia pop 6 (G)0.002028927See
POLPoland DKMS0.002020653See
USAUSA NMDP Alaska Native or Aleut0.00201376See
NLDNetherlands Leiden0.00201305See
DEUGermany pop 60.00208862See
CZECzech Republic NMDR0.00205099See
ESPSpain (Catalunya, Navarra, Extremadura, Aaragón, Cantabria,0.40.00204335See
GRCGreece pop30.40.0020246See
RUSRussia Karelia0.00191075See
INDIndia East UCBB0.40.00192403See
USAUSA NMDP Hispanic South or Central American0.0018146714See
ISRIsrael Morocco Jews0.001836718See
COLColombia Bogotá Cord Blood0.30.00171463See
INDIndia Northeast UCBB0.30.0017296See
USAUSA NMDP North American Amerindian0.001735791See
DEUGermany DKMS - Bosnia and Herzegovina minority0.00151028See
ISRIsrael Ethiopia Jews0.00135928See
DEUGermany DKMS - Spain minority0.00141107See
ISRIsrael Arab pop 20.001312301See
DEUGermany DKMS - Romania minority0.00121234See
USAUSA Hispanic pop 20.00131999See
USAUSA NMDP Caribean Indian0.001014339See
USAUSA Colorado Univ Cord Blood Bank Hispanic0.00101058See
ESPSpain Barcelona0.20.0010941See
USAUSA Caucasian pop 40.00101070See
ISRIsrael Druze0.00095914See
ISRIsrael YemenJews0.000715542See
USAUSA NMDP Caribean Hispanic0.0007115374See
DEUGermany DKMS - Croatia minority0.00072057See
ISRIsrael Ashkenazi Jews pop 30.00064625See
ISRIsrael Poland Jews0.000613871See
HRVCroatia pop 40.00064000See
CHLChile Santiago0.0005920See
ISRIsrael USSR Jews0.000545681See
ISRIsrael Kavkazi Jews0.00052840See
ISRIsrael Tunisia Jews0.00049070See
ISRIsrael Bukhara Jews0.00042317See
USAUSA NMDP Caribean Black0.000433328See
USAUSA African American pop 40.00042411See
USAUSA NMDP African American pop 20.0004416581See
USAUSA NMDP African0.000328557See
ISRIsrael Argentina Jews0.00024307See
INDIndia West UCBB0.00.00025829See
ISRIsrael USA Jews0.00026058See
ISRIsrael Libya Jews0.00013739See
ISRIsrael Iran Jews0.00018153See
ISRIsrael Arab0.0000109See
ITAItaly Rome0.00.0000100See
ITAItaly North pop 30.00.000097See
IRNIran Kurd0.0000100See
ISRIsrael Ashkenazi Jews pop 20.0000132See
ISRIsrael Libyan Jews0.0000119See
ISRIsrael Iranian Jews0.0000101See
ISRIsrael Ethiopian Jews0.0000122See
ISRIsrael Yemenite Jews0.000076See
INDIndia North0.00.000085See
GRCGreece pop 40.000098See
ENGEngland Bedfordshire0.00.0000354See
FRAFrance West0.00.0000100See
CAFCentral African Republic Aka Pygmy0.00.000093See
CANCanada British Columbia Athabaskan0.000062See
CANCanada British Columbia Penutian0.000026See
ARGArgentina Rio Negro Mapuche0.000034See
ARGArgentina Chubut Tehuelche0.000023See
ARGArgentina Salta Wichi0.000024See
ARGArgentina Gran Chaco Eastern Toba0.0000135See
ARGArgentina Gran Chaco Mataco Wichi0.000049See
ARGArgentina Gran Chaco Western Toba Pilaga0.000019See
BRABrazil Kaingang0.0000235See
BRABrazil Guarani M bya0.000093See
BRABrazil Southeast Caucasian0.00.0000103See
BRABrazil Guarani Nandeva0.000086See
BRABrazil Central Plateau Xavante0.000074See
CZECzech Republic Romani0.00.000034See
CHNChina Urumqi Kazak0.000042See
CHNChina Urumqi Uyghur0.00.000057See
CODCongo Kinshasa Bantu0.00.000090See
USAUSA South Texas Hispanic0.0000194See
USAUSA Alaska Yupik0.0000252See
USAUSA Colorado Univ Cord Blood Bank African American0.0000261See
USAUSA Caucasian0.00.000061655See
SAUSaudi Arabia0.00.000018See
RUSRussia Siberia Negidal0.000035See
RUSRussia Siberia Khabarovsk Evenki0.000025See
RUSRussia Siberia Khanty Mansi0.000068See
TUNTunisia Gabes Arab0.000096See
PRTPortugal North0.000046See
PRTPortugal South0.000049See
PRTAzores Oriental Islands0.000043See
PRYParaguay Lengua0.000017See
RUSRussia Tuva Todja0.000022See
RUSRussia Siberia Irkutsk Tofalar0.000043See
RUSRussia Siberia Kushun Buryat0.000025See
MEXMexico Highlands Mestizos0.00.0000160See
MEXMexico Nuevo Leon Mestizo0.00.000040See
PNGPapua New Guinea Lowland Wosera0.000079See
USAUSA Philadelphia Caucasian0.00.0000141See
USAUSA Caucasian Pittsburgh0.00.0000177See
USAUSA Caucasian Bethesda0.00.0000307See
USAUSA African American Bethesda0.00.0000187See

Frequency data at lower resolution for this allele can be found in links below

Allele  Number of Populations 


* Allele Frequency: Total number of copies of the allele in the population sample (Alleles / 2n) in decimal format.
   Important: This field has been expanded to four decimals to better represent frequencies of large datasets (e.g. where sample size > 1000 individuals)
* Phenotype Frequency: Percentage of individuals who have the allele or gene (Individuals / n).
* Allele Frequencies shown in green were calculated from Phenotype Frequencies assuming Hardy-Weinberg proportions.

¹ IMGT/HLA Database - For more details of the allele.
² Distribution - Graphical distribution of the allele.
³ Haplotype Association - Find HLA haplotypes with this allele.
ª Notes - See notes for ambiguous combinations of alleles.


Allele frequency net database (AFND) 2020 update: gold-standard data classification, open access genotype data and new query tools
Gonzalez-Galarza FF, McCabe A, Santos EJ, Jones J, Takeshita LY, Ortega-Rivera ND, Del Cid-Pavon GM, Ramsbottom K, Ghattaoraya GS, Alfirevic A, Middleton D and Jones AR Nucleic Acid Research 2020, 48:D783-8.
Liverpool, U.K.

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