Allele Frequencies in World Populations

HLA Database » Allele Report

The list below shows all populations in AFND that contains the allele. If an allele has an entry with a lower resolution this will be shown at the end.



Allele reported 398 time(s) and present in 390 population(s).

Population Phenotype
Frequency (%)
Distribution² Haplotype³
TURTurkey pop 20.3540228See
ITAItaly North Pavia0.346081See
ITAItaly pop 456.70.34204575See
SDNSudan South Nuba56.50.340446See
TZATanzania Dodoma Kongwa0.3210212See
ARMArmenia living in Lebanon0.3060368See
ALBAlbania pop 249.80.2951432See
ARMArmenia Lori0.2940102See
ITAItaly South Campania Region49.60.29001089See
ARMArmenia Ghegharkunik0.2890242See
ARMArmenia Yerevan0.2870445See
MKDMacedonia MBMDR - Macedonian Muslims47.40.282976See
IRQIraq Erbil55.70.2786372See
GRCGreece North0.2780500See
GRCGreece pop 50.2770500See
ITAItaly Central0.2700380See
KURIraq Kurdistan Region45.90.2610209See
ARMArmenia Shirak0.257076See
ITAItaly North Pavia pop 30.2562685See
ALBAlbanian Kosovo0.2542120See
ITAItaly Lombardy44.20.2540674See
GRCGreece pop 70.252311250See
ITAItaly North Pavia pop 247.20.25002416See
ITAItaly North pop 243.30.24502054See
MKDMacedonia MBMDR - Albanian42.20.2422128See
ARMArmenia living in Iran0.241085See
BFABurkina Faso Rimaibe0.240047See
ESPSpain Majorcans Jews0.2360103See
ITAItaly pop 20.236053See
MKDMacedonia MBMDR - Macedonian41.60.23541283See
ARMArmenia living in Karabakh0.2350445See
PAKPakistan Karachi Parsi0.230091See
ARMArmenia living in USA0.2270233See
ARMArmenia Syunik0.2260117See
ITAItaly pop 641.90.2255184See
ISRIsrael Jews pop 238.60.218023000See
ROMRomania pop 340.10.21581469See
TURTurkey Istanbul38.40.2151250See
ESPSpain Ibiza0.208088See
IRNIran pop 40.2080855See
VENVenezuela Zulia Maracaibo Mixed0.200020See
ROMRomania pop 20.19006936See
HRVCroatia pop 337.50.1875120See
ZAFSouth Africa Limpopo Venda0.1840117See
CZECzech Republic Kurd31.10.182474See
IRNIran Royan Cord Blood Bank32.40.178015600See
INDIndia New Delhi pop 20.1770102See
HRVCroatia pop 20.1760100See
IRQIraq Arabs32.30.1745149See
ARGArgentina Mapuche0.174048See
RUSRussia North Ossetian32.30.1732127See
ITAItaly Sardinia0.173086See
RUSRussia Smolensk0.1730156See
BFABurkina Faso Mossi0.170053See
SRBSerbia pop 331.00.16891992See
GEOGeorgia Kurds0.167030See
PAKPakistan Mixed Pathan0.1600100See
BIHBosnia and Herzegovina pop 228.30.1583120See
FRAFrance Grenoble30.20.15811000See
SRBSerbia Vojvodina27.70.1580400See
CZECzech Republic pop 328.90.1580180See
PAKPakistan Mixed Sindhi0.1560101See
ESPSpain Majorca0.1510407See
FRAFrance Southeast27.70.1500130See
TURTurkey Ankara0.150050See
BFABurkina Faso Fulani0.150049See
BIHBosnia and Herzegovina0.1492134See
SVKSlovakia pop 20.14894234See
ESPSpain Minorca0.145094See
RUSRussia Moscow Pop 226.70.14382000See
AUTAustria Cord Bloods0.14311368See
FRAFrance Lyon27.20.14284813See
BRABrazil Southeast Campinas Mixed26.30.141599See
POLPoland pop 327.70.13882907See
ESPSpain Malaga25.60.1374160See
FRAFrance Marseille27.00.13701000See
BRABrazil REDOME Sao Paulo0.1368800809See
BRABrazil South East Cord Blood0.135111409See
SDNSudan Khartoum0.132798See
MEXMexico Campeche, Campeche city0.132434See
CODCongo Kinshasa expatriates living in Belgium25.00.131075See
FRAFrance South24.50.1310350See
BRABrazil REDOME Espirito Santo0.130488485See
RUSRussia Moscow0.13002650See
BRABrazil Parana Caucasian26.10.13002775See
ARGArgentina La Plata25.00.1300100See
BRABrazil REDOME Parana0.1297341639See
BRABrazil REDOME Rio Grande do Sul0.1292241329See
BRABrazil Sao Paulo Bauru Mixed0.12903542See
BRABrazil South Ribeirao Preto0.1290184See
ESPSpain Valencia24.10.1287577See
MEXMexico Jalisco, Tonala0.128635See
ESPSpain Madrid24.00.1282504See
PRTAzores Terceira Island0.1280130See
USAUSA OPTN African American0.12601510See
PRTPortugal Evora0.1260737See
ESPSpain Northwest23.60.12591818See
FRAFrance Bordeaux23.60.1252990See
RUSRussia Samara Region0.12502500See
BRABrazil Sao Paulo Mixed23.40.1250239See
ESPSpain, Castilla y Leon, Northwest,21.60.12441743See
GBRUnited Kingdom pop 20.1240101See
BRABrazil REDOME Santa Catarina0.1234106673See
BRABrazil Curitiba-Parana Mixed0.1222264See
BRABrazil Rio Grande do Sul Caucasoid0.12204428See
PAKPakistan Baloch0.122066See
MEXMexico Guanajuato, Leon0.121878See
ESPSpain Northwest Lugo22.80.1213145See
USAUSA Southeast African American24.10.1200112See
BRABrazil REDOME Sergipe0.11947321See
RUSRussia Northwest pop 222.30.1190346See
HRVCroatia Gorski Kotar Region0.119063See
PRTPortugal Faro0.11801242See
FRAFrance Grenoble, Nantes and Rennes0.11806094See
BRABrazil REDOME Rio de Janeiro0.1171139322See
BRABrazil REDOME Pernambuco0.115092332See
PRTPortugal Portalegre0.11501254See
BRABrazil North East Mixed0.1150205See
BRABrazil REDOME Bahia0.114147399See
BRABrazil REDOME Mato Grosso0.114034649See
PRTPortugal Setubal0.11405268See
PRTPortugal Coimbra0.11405057See
RUSRussia Northwest22.30.11401011See
ARGArgentina Cuyo Region21.40.1140420See
BRABrazil Parana Cafuzo22.60.1130319See
BRABrazil REDOME Mato Grosso do Sul0.112395667See
PRTPortugal Lisbon0.112017420See
ARGArgentina Buenos Aires pop 220.80.11201216See
PRTPortugal South pop 20.11101021See
BRABrazil REDOME Minas Gerais0.1105211275See
BRABrazil REDOME Alagoas0.110125349See
RUSRussia Northwest pop 320.00.1100100See
BRABrazil Parana Afro Brazilian22.10.110077See
PAKPakistan Brahui0.1100104See
MEXMexico Baja Californa, Mexicali0.1100100See
BRABrazil REDOME Rondonia0.109454396See
PRTPortugal Porto0.10907937See
INDIndia Tamil Nadu Dravidian0.1090156See
RUSRussia Tatars0.1084355See
MEXMexico Veracruz, Orizaba0.108360See
BRABrazil Minas Gerais State Mixed20.50.10801000See
PRTPortugal Guarda0.1080797See
POLPoland Lodz0.1070103See
BRABrazil REDOME Paraiba0.106143868See
PRTPortugal Leiria0.10601847See
PRTPortugal Santarem0.10603865See
BRABrazil REDOME Federal District0.105729549See
PRTPortugal Beja0.1050699See
RUSRussia South Ural Tatar20.00.1040135See
BRABrazil REDOME Goias0.103788574See
BRABrazil REDOME Acre0.1030859See
PRTPortugal Aveiro0.10305933See
PRTPortugal Bragança0.1030301See
BRABrazil REDOME Tocantins0.102320692See
INDIndia North Gujarat19.50.1021338See
MEXMexico Zacatecas, Zacatecas city0.101284See
MEXMexico Sinaloa Rural0.1011183See
BRABrazil Mato Grosso do Sul0.1010203See
BRABrazil REDOME Rio Grande do Norte0.100946603See
BRABrazil Rio Grande do Sul Mixed0.1000324See
TTOTrinidad African0.100067See
MEXMexico Veracruz, Poza Rica0.100045See
BRABrazil REDOME Ceara0.0998101217See
BRABrazil REDOME Maranhao0.099510180See
MEXMexico Durango Rural0.0994326See
PRTMadeira pop 30.0990538See
BRABrazil Rio Grande do Norte Mestizo0.098012973See
PRTPortugal Center pop 20.0980562See
MEXMexico San Luis Potosi Rural0.097787See
MEXMexico Tapachula, Chiapas Mestizo Population18.10.097272See
MARMorocco pop 20.0970110See
RUSRussia South Ural Russian18.80.0970207See
PRTPortugal Vila Real0.09701167See
PRTPortugal North pop 20.09661801See
PRTPortugal Castelo Branco0.0960327See
TWNTaiwan Hakka pop 20.0960714See
MEXMexico Coahuila, Saltillo0.095972See
MEXMexico Coahuila, Torreon0.0950396See
PRTPortugal Braga0.09501971See
RUSRussia Vologda0.0950121See
BRABrazil REDOME Para0.094972637See
BRABrazil REDOME Piaui0.094646140See
BRABrazil Para State18.90.09465000See
GBRUnited Kingdom Central0.0940135See
BRABrazil Piaui Mixed0.094021943See
BRABrazil Parana Mixed race18.80.0940186See
PAKPakistan Kalash0.094069See
VENVenezuela Valencia and Maracaibo Caracus Mixed0.094096See
USAUSA OPTN Caucasian0.09408525See
MEXMexico Durango, Durango city0.0935153See
INDIndia North pop 30.0928587See
PRTPortugal Viseu0.09202915See
BRABrazil Rio Grande do Sul Black0.0920248See
BRABrazil REDOME Roraima0.09194140See
PRTPortugal Viana do Castelo0.0910706See
SAUSaudi Arabia pop 415.80.0904499See
MYSMalaysia Negeri Sembilan Minangkabau0.090034See
AREUnited Arab Emirates pop 217.20.0900373See
TTOTrinidad South Asian0.090087See
MARMorocco Souss Region0.090098See
MEXMexico Quintana Roo Rural0.090050See
MEXMexico Sinaloa Mestizo0.089056See
BRABrazil REDOME Amapa0.088417864See
CHLChile Huilliche0.088040See
CUBCuba Mixed pop 20.0880189See
BRABrazil Para Cord Blood Unit17.10.0880841See
MEXMexico Mexico City Center0.0877152See
MEXMexico Mestizo pop 40.0874269See
ESPSpain Andalusia Romani0.087099See
MEXMexico Tamaulipas, Ciudad Victoria0.087023See
FRAFrance Rennes pop 417.20.08651000See
MEXMexico Guanajuato Rural0.0859162See
RUSRussia, South Ural, Chelyabinsk region, Nagaybaks16.10.0850112See
IRNIran Baloch0.0850100See
GBRUnited Kingdom East0.0849163See
MEXMexico Jalisco, Tlajomulco0.083330See
INDIndia Bikaner Non-Raikas16.00.0830127See
MEXMexico Guadalajara Mestizo0.083054See
JPNJapan pop 80.0830308See
MEXMexico Nayarit, Tepic0.082597See
MEXMexico Veracruz, Veracruz city0.0814171See
BRABrazil REDOME Amazonas0.081324129See
TWNTaiwan Minnan pop 20.08007137See
TWNTaiwan Aborigine0.0800111See
MEXMexico Baja California Rural0.080050See
MEXMexico Chihuahua Chihuahua City0.0798119See
MEXMexico Chihuahua, Ciudad Juarez0.0787106See
ESPSpain Malaga Romani15.00.078080See
SAUSaudi Arabia pop 20.0780383See
AUSAustralia South and East Caucasian15.00.07801210See
MEXMexico Sinaloa, Culiacán0.0777103See
MEXMexico Jalisco, Zapopan0.0774168See
MEXMexico Zacatecas Rural0.0762266See
CZECzech Republic Romani pop 215.20.076146See
PAKPakistan Burusho0.075092See
TWNTaiwan Chinese immigrants from Middle China0.0740211See
USAUSA OPTN Hispanic0.07401580See
ARGArgentina Corrientes15.50.0740155See
MEXMexico Mexico City West0.073533See
MEXMexico Sonora, Ciudad Obregón0.0734143See
MEXMexico Nuevo Leon, Monterrey city0.0730226See
AUSAustralia West Caucasian14.00.0730891See
CHNChina Shaanxi Province Han0.072010000See
MEXMexico Veracruz, Coatzacoalcos0.071455See
MEXMexico Zacatecas, Fresnillo0.0714103See
MEXMexico Tamaulipas Rural0.0714125See
GHAGhana Accre Asutuare Akan0.0710429See
CHNChina Shandong Province Linqu County13.70.0710139See
USAUSA OPTN Asian0.0710261See
ENGEngland Sheffield13.50.06994755See
MEXMexico Michoacan, Morelia0.0695150See
SWESweden pop 413.50.0694966See
MEXMexico Mexico City Metropolitan Area Rural0.0691150See
MEXMexico Sonora Rural0.0685197See
MEXMexico Jalisco, Guadalajara city0.06781189See
INDIndia Tamil Nadu Chennai13.10.0678137See
MEXMexico Yucatan Rural0.0672132See
MEXMexico Morelos Rural0.066730See
MEXMexico San Luis Potosi, San Luis Potosi city0.066730See
MEXMexico Yucatan, Merida0.0667192See
MEXMexico Michoacan Rural0.0659348See
MEXMexico Jalisco Rural0.0657585See
MEXMexico Sonora, Hermosillo0.065799See
GBRUnited Kingdom South West0.0654163See
ENGEngland North West Mixed pop 212.40.0633379See
CHNChina Han12.10.0624314See
CHNChina Shanghai0.062026266See
RUSRussia South Ural Bashkir11.60.0620146See
MEXMexico Nuevo Leon Rural0.0614439See
ENGEngland Leeds11.90.06135024See
BRABrazil Parana Oriental12.10.061033See
INDIndia Andhra Pradesh Sunni3.10.0600100See
RUSRussia Kostroma Region0.0600126See
SWESweden pop 50.05901569See
SWESweden Stockholm11.40.05901347See
MEXMexico Queretaro Rural0.058143See
CHNChina Beijing and Guangzhou0.05801592See
RUSRussia Arkhangelsk Pomor0.058063See
WALWales pop 211.20.058039979See
CHNChina Guangdong Province11.20.0576403See
SDNSudan East Rashaida11.10.057127See
ENGEngland Manchester11.10.05711640See
THAThailand pop 40.057016807See
MEXMexico Chihuahua Rural0.0565236See
ECUEcuador Andes Mixed Ancestry0.0564824See
CHNChina Shandong Province10.90.05607418See
THAThailand pop 20.0560124See
MEXMexico Queretaro, Queretaro city0.055645See
MEXMexico Coahuila Rural0.0550216See
TWNTaiwan Chinese immigrants from South China0.0550172See
RUSRussia Arkhangelsk0.055081See
GBRUnited Kingdom North0.0550330See
MEXMexico Nayarit Rural0.054764See
MMRMyanmar Mon10.90.054764See
MMRMyanmar Bamar10.90.054346See
MEXMexico Veracruz, Cordoba0.053656See
ENGEngland Lancaster10.40.0534545See
CHNChina Jiangsu Province0.053020248See
ECUEcuador Mixed Ancestry0.05241173See
MMRMyanmar Rakhine10.40.052148See
MEXMexico Jalisco, Tlaquepaque0.051339See
ESPSpain North10.00.0513156See
MEXMexico Puebla Mestizo0.051099See
MEXMexico Mexico City Mestizo0.0500121See
IRLIreland Wexford10.00.0500200See
MEXMexico mestizo pop 30.0497201See
MEXMexico Chiapas Rural0.0496121See
PERPeru Arequipa Mestizo9.60.0490168See
MEXMexico Tabasco, Villahermosa0.048882See
MEXMexico Hidalgo, Pachuca0.048841See
MEXMexico Guerrero state0.0486144See
MEXMexico Oaxaca Rural0.0483485See
MEXMexico Mexico City South0.048152See
ENGEngland Liverpool9.40.04811343See
ENGEngland Newcastle9.30.04762739See
MEXMexico Chiapas, Tuxtla Gutierrez0.047252See
NORNorway ethnic Norwegians9.30.04724510See
MEXMexico Baja California, La Paz0.046775See
PERPeru Quechua0.046044See
MEXMexico Colima Rural0.045543See
COLColombia Guajira Peninsula Wayuu0.045088See
KORSouth Korea pop 80.04507096See
MEXMexico Puebla, Puebla city0.04461994See
ECUEcuador Coast Mixed Ancestry0.0441238See
MEXMexico Veracruz Rural0.0434539See
GTMGuatemala, Guatemala City Mixed Ancestry8.70.0433127See
FRAFrance West Breton0.0430150See
MYSMalaysia Perak and Johor Banjar Bugis Jawa0.043094See
RUSRussia Murmansk Saomi Mixed0.043070See
GBRUnited Kingdom Orkney0.042988See
SDNSudan Central Shaigiya Mixed8.30.042436See
MEXMexico Tabasco Rural0.0423142See
TWNTaiwan Chinese immigrants from North China0.0410152See
IRLIreland South pop 20.040317624See
MEXMexico Veracruz, Xalapa0.0401187See
MYSMalaysia Perak Rawa0.040023See
IRLIreland Donegal8.00.0400200See
MMRMyanmar Kachin7.90.039763See
PHLPhilippines National Capital Region0.039051See
JPNJapan pop 100.0390332See
MEXMexico Tlaxcala Rural0.0386830See
ECUEcuador Amazonia Mixed Ancestry0.038539See
MEXMexico Aguascalientes state0.036895See
MEXMexico Morelos, Cuernavaca0.036682See
MEXMexico Puebla Rural0.0342833See
MEXMexico Oaxaca, Oaxaca city0.0331151See
MEXMexico Quintana Roo, Cancun0.031348See
MEXMexico Hidalgo Rural0.030981See
BGDBangladesh Dhaka Bangalee0.0280141See
MYSMalaysia pop 30.02801445See
MMRMyanmar Chin5.50.027355See
MMRMyanmar Kayah5.50.027355See
INDIndia Andhra Pradesh Brahmin1.30.026098See
ARGArgentina Salta Wichi pop 25.30.026019See
INDIndia sub-Himalayan West Bengal Kami5.10.0253158See
LKASri Lanka Colombo Sinhalese0.0250101See
MEXMexico Colima, Colima city0.024661See
INDIndia Bikaner Raikas4.50.0230143See
MEXMexico Guanajuato, Guanajuato city0.022722See
MEXMexico Tlaxcala, Tlaxcala city0.0221181See
MEXMexico Mexico City East0.018879See
MMRMyanmar Shan3.70.018554See
RUSRussia Nenet Mixed0.018055See
MEXMexico Mexico City North0.0173751See
BRABrazil Kaingang0.0150235See
COLColombia Antioquia Paisa0.0150100See
MEXMexico Sonora Seri0.015034See
ITAItaly Sardinia pop23.00.01501129See
BRABrazil Guarani M bya0.011093See
MEXMexico Campeche Rural0.010647See
VNMVietnam Hanoi0.010050See
COLColombia Sierra Nevada de Santa Marta Arhuaco0.0080107See
MYSMalaysia pop 20.008062See
ESPSpain Gipuzkoa Basque0.0000100See
ESPSpain Catalonia Girona0.000088See
ARGArgentina Kolla0.000061See
BRABrazil East Amazon0.000041See
PRYParaguay Aché0.000087See
MEXMexico Huasteca Region Teenek0.000055See
ARGArgentina Chiriguano0.00.000054See
MEXMexico Baja California, Tijuana0.000025See

Frequency data at lower resolution for this allele can be found in links below

Allele  Number of Populations 


* Allele Frequency: Total number of copies of the allele in the population sample (Alleles / 2n) in decimal format.
   Important: This field has been expanded to four decimals to better represent frequencies of large datasets (e.g. where sample size > 1000 individuals)
* Phenotype Frequency: Percentage of individuals who have the allele or gene (Individuals / n).
* Allele Frequencies shown in green were calculated from Phenotype Frequencies assuming Hardy-Weinberg proportions.

¹ IMGT/HLA Database - For more details of the allele.
² Distribution - Graphical distribution of the allele.
³ Haplotype Association - Find HLA haplotypes with this allele.
ª Notes - See notes for ambiguous combinations of alleles.


Allele frequency net database (AFND) 2020 update: gold-standard data classification, open access genotype data and new query tools
Gonzalez-Galarza FF, McCabe A, Santos EJ, Jones J, Takeshita LY, Ortega-Rivera ND, Del Cid-Pavon GM, Ramsbottom K, Ghattaoraya GS, Alfirevic A, Middleton D and Jones AR Nucleic Acid Research 2020, 48:D783-8.
Liverpool, U.K.

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