Allele Frequencies in World Populations

HLA Database » Allele Report

The list below shows all populations in AFND that contains the allele. If an allele has an entry with a lower resolution this will be shown at the end.



Allele reported 267 time(s) and present in 227 population(s).

Population Phenotype
Frequency (%)
Distribution² Haplotype³
IRNIran Kurd0.2050100See
IRNIran Azeri0.1850100See
CHNChina Urumqi Uyghur10.50.053057See
ESPSpain Tenerife Island0.044083See
ITAItaly Bergamo7.90.0410101See
COLColombia Providencia Island African0.033030See
ITAItaly Rome6.00.0300100See
ISRIsrael Libyan Jews0.0300119See
SAUSaudi Arabia5.90.029918See
CANCanada Cree NA-DHS_3 (G)5.60.027818See
CHNChina Urumqi Han0.025059See
ISRIsrael Libya Jews0.02503739See
ISRIsrael Argentina Jews0.02334307See
ITAItaly Central0.0230380See
GRCGreece Crete0.0220135See
PRTPortugal Azores Terceira Island3.50.0219130See
USAUSA Philadelphia Caucasian4.30.0210141See
GRCCretan Islanders0.0202124See
ITAItaly North pop 34.10.020097See
PRTAzores Terceira Island0.0200130See
MKDMacedonia pop 20.019080See
DEUGermany DKMS - Italy minority0.01811159See
ESPSpain Las Alpujarras0.017685See
LBNLebanon Niha el Shouff0.017061See
TURTurkey pop 10.0160250See
GRCGreece pop23.30.0160120See
INDIndia Northeast Shia0.0160190See
DEUGermany DKMS - Romania minority0.01581234See
CHESwitzerland Lausanne0.0155993See
CHLChile Mapuche0.015466See
CHLChile Santiago Mixed3.00.015170See
FRAFrance West3.00.0151100See
CHESwitzerland Geneva pop 20.01511267See
DEUGermany DKMS - Austria minority0.01501698See
ITAItaly pop 50.0150975See
CZECzech Republic Romani2.90.014634See
GRCGreece pop 60.0145242See
RUSRussia Bering Island Aleuts0.0144104See
USAUSA Caucasian Pittsburgh2.80.0140177See
USAUSA Caucasian Bethesda2.80.0140307See
CHESwitzerland Lugano0.01391169See
DEUGermany pop 32.70.0135111See
CHESwitzerland Luzern0.01331553See
DEUGermany DKMS - France minority0.01321406See
FRAFrance Rennes0.0130200See
INDIndia Northeast Kayastha0.0130190See
ISRIsrael Ashkenazi Jews0.013080See
MKDMacedonia pop 10.0130158See
CHNChina, Xinjiang Uyghur Autonomous Region Han2.50.012570See
CZECzech Republic NMDR0.01225099See
BRABrazil Southeast Mixed Race2.40.012042See
CHESwitzerland Sion0.0120832See
CHESwitzerland Aargau-Solothurn0.01141838See
DEUGermany pop 80.011339689See
ISRIsrael Moroccan Jews0.0110113See
CHESwitzerland Bern0.01083545See
DEUGermany DKMS - Turkey minority0.01034856See
DEUGermany pop 60.01038862See
FRAFrance Rennes pop 30.0100200See
BRABrazil Mixed0.0100108See
ARGArgentina Buenos Aires1.90.0100466See
ARMArmenia combined Regions0.0100100See
INDIndia Northeast Rajbanshi0.010098See
RUSRussia Transbaikal Territory Buryats2.00.0100150See
SCOScotland Orkney1.90.010099See
ESPSpain Andalusia0.010099See
POLPoland Wielkopolska Region0.010099See
MNGMongolia Khalkha0.0100200See
MARMorocco Settat Chaouya0.010098See
MARMorocco Atlantic Coast Chaouya0.010098See
RUSRussia Karelia0.00991075See
POLPoland DKMS0.009820653See
DEUGermany DKMS - German donors0.00963456066See
CHESwitzerland Zurich0.00954875See
RUSRussia Nizhny Novgorod, Russians1.90.00931510See
ESPSpain Granada0.0090280See
PRTAzores Central Islands0.009059See
MKDMacedonia pop 30.0090172See
HRVCroatia pop 40.00884000See
USAUSA NMDP Middle Eastern or North Coast of Africa0.008670890See
GEOGeorgia Caucasus Tbilisi0.0084119See
CHESwitzerland St Gallen0.00822113See
DEUGermany DKMS - Croatia minority0.00812057See
ENGEngland North West1.70.0080298See
INDIndia Northeast Lachung0.008058See
INDIndia Northeast Mech0.008063See
ISRIsrael Ashkenazi Jews pop 20.0080132See
INDIndia Lucknow1.70.0080123See
ESPSpain Murcia0.0080173See
NLDNetherlands UMCU1.60.007864See
ESPSpain (Catalunya, Navarra, Extremadura, Aaragón, Cantabria,1.60.00784335See
BRABrazil Paraná Caucasian1.60.0078641See
USAUSA Caucasian pop 40.00771070See
MEXMexico Tixcacaltuyub Maya0.007567See
DEUGermany DKMS - Portugal minority0.00741176See
INDIndia Uttar Pradesh0.0070202See
INDIndia Northeast Mathur0.0070155See
BRABrazil Mato Grosso do Sul0.0070203See
CRICosta Rica Central Valley Mestizo (G)1.40.0070221See
NICNicaragua Mestizo (G)1.40.0070155See
SVNSlovenia pop 21.40.0070140See
USAUSA Caucasian pop 50.0070268See
USAUSA South Texas Hispanic0.0070194See
USAUSA San Francisco Caucasian0.0070220See
USAUSA African American Bethesda1.40.0070187See
USAUSA Southern California Mestizo1.40.007073See
USAUSA Minnesota Olmsted0.0070339See
FRAFrance French Bone Marrow Donor Registry0.006742623See
ECUEcuadorean Amerindians0.006775See
DEUGermany DKMS - Netherlands minority0.00661374See
DEUGermany DKMS - Spain minority0.00631107See
CHESwitzerland Basel0.00621888See
USAUSA NMDP European Caucasian0.00611242890See
USAUSA Caucasian Houston1.20.0060194See
ESPSpain Barcelona1.30.0060941See
RUSRussia Chuvash0.006082See
DEUGermany Essen1.20.0060174See
GRCGreece pop 81.20.006083See
ISRIsrael Non Ashkenazi Jews0.006080See
USAUSA Hispanic pop 20.00581999See
DEUGermany DKMS - Bosnia and Herzegovina minority0.00541028See
RUSRussia Bashkortostan, Tatars1.00.0052192See
SDNSudan Mixed1.00.0050200See
TUNTunisia pop 30.0050104See
PERPeru Titikaka Lake Uro0.0050105See
PERPeru Titikaka Lake Uros0.0050105See
USAUSA South Dakota Sioux0.0050101See
USAUSA Mexican American Mestizo0.0050553See
USAUSA Colorado Univ Cord Blood Bank Caucasian0.00503830See
USAUSA Colorado Univ Cord Blood Bank Hispanic0.00501058See
CRICosta Rica Guanacaste Mestizo (G)1.00.0050110See
CZECzech Republic0.0050106See
CZECzech Republic pop 21.00.005099See
DZAAlgeria Oran0.0050100See
ISRIsrael Arab0.0050109See
INDIndia Northeast Rastogi0.0050196See
INDIndia Northeast Sunni0.0050188See
INDIndia Delhi0.0050112See
DEUGermany DKMS - United Kingdom minority0.00491043See
DEUGermany DKMS - Greece minority0.00481894See
ISRIsrael Arab pop 20.004512301See
USAUSA San Antonio Caucasian0.0045222See
RUSRussia Bashkortostan, Bashkirs0.80.0042120See
IRNIran pop 20.0041120See
USAUSA NMDP Mexican or Chicano0.0041261235See
USAUSA Italy Ancestry0.0040273See
USAUSA NMDP American Indian South or Central America0.00405926See
USAUSA Eastern European0.0040558See
LBYLibya Cyrenaica0.0040118See
NIRIreland Northern0.70.00401000See
ISRIsrael Ethiopian Jews0.0040122See
FRAFrance Southeast0.80.0040130See
CHNChina Yunnan Province Han pop 20.0040129See
BRABrazil North East Mixed0.0040205See
CHLChile Santiago0.0037920See
USAUSA Caucasian0.70.003561655See
USAUSA NMDP Hispanic South or Central American0.0034146714See
USAUSA NMDP North American Amerindian0.003335791See
RUSRussia Belgorod region0.70.0033153See
USAUSA NMDP Caribean Hispanic0.0030115374See
USAUSA NMDP Caribean Indian0.003014339See
USAUSA NMDP Alaska Native or Aleut0.00301376See
USAUSA African American pop 70.0030193See
SWESweden Northern Sami0.0030154See
LBNLebanon pop 20.0030191See
NLDNetherlands Leiden0.00301305See
PRTMadeira pop 20.0030173See
NZLNew Zealand Maori0.0030200See
CHNChina Harbin Manchu0.0030172See
FINFinland pop20.0030150See
GAZGaza Palestinians0.0030165See
INDIndia Northeast Vaish0.0030198See
ISRIsrael USSR Jews0.002845681See
ISRIsrael Poland Jews0.002613871See
CHESwitzerland Graubunden0.0024759See
USAUSA NMDP Hawaiian or other Pacific Islander0.002311499See
ISRIsrael Kavkazi Jews0.00212840See
ISRIsrael Ashkenazi Jews pop 30.00214625See
COLColombia Bogotá Cord Blood0.40.00211463See
CHNChina Harbin Korean0.0020201See
CHNChina Inner Mongolia Autonomous Region Northeast0.40.0020496See
USAUSA Spain Ancestry0.0020279See
USAUSA Colorado Univ Cord Blood Bank African American0.0020261See
ISRIsrael Tunisia Jews0.00189070See
ISRIsrael Morocco Jews0.001836718See
ISRIsrael Druze0.00175914See
ENGEngland Bedfordshire0.30.0015354See
NICNicaragua Managua0.30.0015339See
ISRIsrael USA Jews0.00126058See
AREUnited Arab Emirates Pop 10.0010570See
USAUSA San Diego0.20.0010496See
USAUSA NMDP Caribean Black0.001033328See
ISRIsrael Iraq Jews0.000913270See
ISRIsrael Bukhara Jews0.00092317See
DEUGermany DKMS - China minority0.00081282See
ISRIsrael Georgia Jews0.00074471See
USAUSA NMDP African American pop 20.0007416581See
SAUSaudi Arabia pop 6 (G)0.000728927See
USAUSA African American pop 40.00062411See
CHNChina Zhejiang Han pop 20.0006833See
USAUSA NMDP Southeast Asian0.000527978See
MYSMalaysia Peninsular Malay0.10.0005951See
USAUSA NMDP African0.000528557See
INDIndia North UCBB0.10.00035849See
USAUSA NMDP Filipino0.000350614See
INDIndia Central UCBB0.10.00024204See
USAUSA NMDP South Asian Indian0.0002185391See
INDIndia East UCBB0.00.00022403See
INDIndia Tamil Nadu0.00022492See
KORSouth Korea pop 100.00024128See
USAUSA NMDP Korean0.000277584See
INDIndia West UCBB0.00.00025829See
HKGHong Kong Chinese cord blood registry0.00013892See
ISRIsrael Iran Jews0.00018153See
USAUSA NMDP Japanese0.000124582See
ISRIsrael YemenJews0.000115542See
USAUSA NMDP Chinese0.000199672See
USAUSA NMDP Vietnamese0.000143540See
INDIndia South UCBB0.00.000011446See
GRCGreece pop 40.000098See
ISRIsrael Yemenite Jews0.000076See
ISRIsrael Iranian Jews0.0000101See
LBNLebanon Kafar Zubian0.000094See
JPNJapan Hyogo Osaka and Nagano0.0000195See
KORSouth Korea pop 30.0000485See
KORSouth Korea pop 20.00.0000207See
DZAAlgeria pop 20.00.0000106See
CAFCentral African Republic Aka Pygmy0.00.000093See
CHNChina Yunnan Province Naxi0.0000118See
CHNChina Urumqi Kazak0.000042See
COLColombia Bogota and Medellin Mestizo0.000065See
BRABrazil Central Plateau Xavante0.000074See
BRABrazil Southeast Caucasian0.00.0000103See
CANCanada British Columbia Athabaskan0.000062See
CANCanada British Columbia Penutian0.000026See
ARGArgentina Rio Negro Mapuche0.000034See
ARGArgentina Chubut Tehuelche0.000023See
ARGArgentina Salta Wichi0.000024See
ARGArgentina Gran Chaco Eastern Toba0.0000135See
ARGArgentina Gran Chaco Mataco Wichi0.000049See
ARGArgentina Gran Chaco Western Toba Pilaga0.000019See
BRABrazil Kaingang0.0000235See
CODCongo Kinshasa Bantu0.00.000090See
USAUSA Colorado Univ Cord Blood Bank Asian0.0000100See
USAUSA Alaska Yupik0.0000252See
USAUSA Asian pop 20.00001772See
LBNLebanon Yuhmur0.000082See
MEXMexico Highlands Mestizos0.00.0000160See
MEXMexico Nuevo Leon Mestizo0.00.000040See
MNGMongolia Oold0.0000104See
MNGMongolia Tsaatan0.0000144See
MNGMongolia Hoton0.000085See
MNGMongolia Khalkha pop 20.0000202See
MARMorocco Nador Metalsa0.000099See
PRYParaguay Lengua0.000017See
PRTAzores Oriental Islands0.000043See

Frequency data at lower resolution for this allele can be found in links below

Allele  Number of Populations 


* Allele Frequency: Total number of copies of the allele in the population sample (Alleles / 2n) in decimal format.
   Important: This field has been expanded to four decimals to better represent frequencies of large datasets (e.g. where sample size > 1000 individuals)
* Phenotype Frequency: Percentage of individuals who have the allele or gene (Individuals / n).
* Allele Frequencies shown in green were calculated from Phenotype Frequencies assuming Hardy-Weinberg proportions.

¹ IMGT/HLA Database - For more details of the allele.
² Distribution - Graphical distribution of the allele.
³ Haplotype Association - Find HLA haplotypes with this allele.
ª Notes - See notes for ambiguous combinations of alleles.


Allele frequency net database (AFND) 2020 update: gold-standard data classification, open access genotype data and new query tools
Gonzalez-Galarza FF, McCabe A, Santos EJ, Jones J, Takeshita LY, Ortega-Rivera ND, Del Cid-Pavon GM, Ramsbottom K, Ghattaoraya GS, Alfirevic A, Middleton D and Jones AR Nucleic Acid Research 2020, 48:D783-8.
Liverpool, U.K.

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