Allele Frequencies in World Populations

HLA Database Allele Report

The list below shows all populations in AFND that contains the allele. If an allele has an entry with a lower resolution this will be shown at the end.



Allele reported 153 time(s) and present in 80 population(s).

Population Phenotype
Frequency (%)
Distribution² Haplotype³
RUSRussia Sakhalin Island Nivkhi0.094053See
RUSRussia Siberia Ulchi0.089073See
MNGMongolia Oold0.0700104See
RUSRussia Siberia Khabarovsk Evenki0.060025See
RUSRussia Siberia Negidal0.057035See
JPNJapan Hokkaido Ainu0.050050See
CHNChina Yunnan Bulang0.0470116See
THAThailand Bangkok pop 20.040050See
CHNChina Inner Mongolia Region Ewenki0.037094See
MYSMalaysia Champa6.90.034029See
THAThailand Northeast0.033066See
THAThailand Northeast pop 20.0260400See
MYSMalaysia Sabah Kadazan0.026057See
RUSRussia Siberia Dudinka Nganasan0.021024See
THAThailand Bangkok pop 30.0190187See
MYSMalaysia Mandailing3.70.019027See
CHNChina Wanwei, Wutou and Shanxin Islands Jing0.0180138See
ESPSpain Tenerife Island0.014083See
INDIndia Northeast UCBB2.40.0118296See
MYSMalaysia Sabah Dusun0.010048See
POLPoland Wielkopolska Region0.010099See
RUSRussia Transbaikal Territory Buryats2.00.0100150See
USAUSA Colorado Univ Cord Blood Bank Asian0.0100100See
CHNChina Harbin Manchu0.0090172See
USAUSA NMDP Vietnamese0.008043540See
INDIndia East UCBB1.30.00652403See
GEOGeorgia Svaneti Region Svan0.006080See
MYSMalaysia Peninsular Chinese1.00.0052194See
MNGMongolia Khalkha0.0050200See
CHNChina Harbin Korean0.0050201See
CHNChina Lijiang Naxi0.0050100See
CHNChina Yunnan Province Han pop 20.0040129See
CHNChina Southwest Dai0.0040124See
MYSMalaysia Peninsular Indian0.70.0037271See
INDIndia South UCBB0.70.003611446See
USAUSA NMDP Southeast Asian0.003427978See
USAUSA Asian pop 20.00311772See
INDIndia Northeast Kayastha0.0030190See
INDIndia Central UCBB0.60.00304204See
INDIndia West UCBB0.50.00265829See
HKGHong Kong Chinese BMDR0.00227595See
CHNChina Marrow Donor Registry0.0020600See
ARGArgentina Buenos Aires0.50.0020466See
CHNChina Beijing Shijiazhuang Tianjian Han0.0020618See
KORSouth Korea pop 10.0020324See
USAUSA NMDP Caribean Indian0.002014339See
HKGHong Kong Chinese cord blood registry0.00193892See
KORSouth Korea pop 100.00194128See
INDIndia North UCBB0.40.00195849See
USAUSA NMDP Chinese0.001799672See
USAUSA NMDP South Asian Indian0.0016185391See
MYSMalaysia Peninsular Malay0.30.0016951See
TWNTaiwan Tzu Chi Morrow Donor Registry0.001646682See
DEUGermany DKMS - China minority0.00121282See
LKASri Lanka Colombo0.10.0010714See
KORSouth Korea pop 30.0010485See
USAUSA NMDP American Indian South or Central America0.00105926See
TWNTaiwan Han Chinese0.0010504See
INDIndia Tamil Nadu0.00092492See
USAUSA NMDP Korean0.000977584See
USAUSA NMDP Filipino0.000850614See
USAUSA NMDP Hawaiian or other Pacific Islander0.000811499See
JPNJapan pop 170.00073078See
JPNJapan pop 160.000218604See
DEUGermany DKMS - Greece minority0.00031894See
DEUGermany DKMS - Turkey minority0.00024856See
DEUGermany pop 80.000139689See
HRVCroatia pop 40.00014000See
CHNChina Hubei Han0.00.00013732See
USAUSA NMDP Middle Eastern or North Coast of Africa0.000170890See
USAUSA NMDP African0.000128557See
USAUSA NMDP African American pop 20.0000416581See
ISRIsrael Iraq Jews0.000013270See
USAUSA NMDP Caribean Hispanic0.0000115374See
USAUSA NMDP European Caucasian0.00001242890See
ISRIsrael USSR Jews0.000045681See
DEUGermany DKMS - German donors0.00003456066See
USAUSA NMDP Mexican or Chicano0.0000261235See
USAUSA NMDP Hispanic South or Central American0.0000146714See
USAUSA Hispanic pop 20.00001999See
USAUSA Philadelphia Caucasian0.00.0000141See
USAUSA African American pop 40.00002411See
USAUSA Colorado Univ Cord Blood Bank Caucasian0.00003830See
USAUSA Colorado Univ Cord Blood Bank Hispanic0.00001058See
USAUSA Caucasian Houston0.00.0000194See
USAUSA Caucasian Pittsburgh0.00.0000177See
USAUSA Caucasian Bethesda0.00.0000307See
USAUSA African American Bethesda0.00.0000187See
WSMSamoa West0.000022See
TWNTaiwan Tzu Chi Morrow Donor Registry Aborigine0.0000233See
USAUSA Caucasian0.00.000061655See
USAUSA San Antonio Caucasian0.0000222See
USAUSA South Texas Hispanic0.0000194See
USAUSA Alaska Yupik0.0000252See
USAUSA Colorado Univ Cord Blood Bank African American0.0000261See
TWNTaiwan Aborigine pop 20.000048See
POLPoland DKMS0.000020653See
PRYParaguay Lengua0.000017See
RUSRussia Siberia Lower Yenisey Ket0.000017See
RUSRussia Tuva pop30.000044See
RUSRussia Tuva Todja0.000022See
RUSRussia Siberia Irkutsk Tofalar0.000043See
RUSRussia Siberia Kushun Buryat0.000025See
RUSRussia Siberia Khanty Mansi0.000068See
NIRIreland Northern0.00.00001000See
NLDNetherlands Leiden0.00001305See
PNGPapua New Guinea East New Britain Tolai0.000048See
PNGPapua New Guinea Highland pop20.000028See
ESPSpain Barcelona0.00.0000941See
ESPSpain Murcia0.0000173See
CODCongo Kinshasa Bantu0.00.000090See
COLColombia Bogota and Medellin Mestizo0.000065See
CZECzech Republic0.0000106See
DEUGermany pop 60.00018862See
INDIndia Northeast Mathur0.0000155See
INDIndia Northeast Rastogi0.0000196See
INDIndia Northeast Vaish0.0000198See
INDIndia Northeast Shia0.0000190See
INDIndia Northeast Sunni0.0000188See
CHNChina Yunnan Province Naxi0.0000118See
CHNChina Urumqi Uyghur0.00.000057See
ARGArgentina Chubut Tehuelche0.000023See
ARGArgentina Salta Wichi0.000024See
ARGArgentina Rio Negro Mapuche0.000034See
BORBorneo Bandjarmasin0.000021See
BRABrazil North East Mixed0.0000205See
BRABrazil Kaingang0.0000235See
BRABrazil Southeast Caucasian0.00.0000103See
BRABrazil Southeast Mixed Race0.00.000042See
CAFCentral African Republic Aka Pygmy0.00.000093See
CANCanada British Columbia Athabaskan0.000062See
CANCanada British Columbia Penutian0.000026See
ITAItaly Rome0.00.0000100See
ITAItaly North pop 30.00.000097See
ITAItaly Bergamo0.00.0000101See
ITAItaly pop 50.0000975See
FRAFrance West0.00.0000100See
INDIndia Northeast Lachung0.000058See
INDIndia Northeast Mech0.000063See
INDIndia Northeast Rajbanshi0.000098See
INDIndia North0.00.000085See
JPNJapan Hyogo Osaka and Nagano0.0000195See
KORSouth Korea pop 20.00.0000207See
MARMorocco Nador Metalsa0.000099See
MARMorocco Settat Chaouya0.000098See
MEXMexico Highlands Mestizos0.00.0000160See
MEXMexico Nuevo Leon Mestizo0.00.000040See
MKDMacedonia pop 10.0000158See
MNGMongolia Tsaatan0.0000144See
MNGMongolia Hoton0.000085See
MNGMongolia Khalkha pop 20.0000202See

Frequency data at lower resolution for this allele can be found in links below

Allele  Number of Populations 


* Allele Frequency: Total number of copies of the allele in the population sample (Alleles / 2n) in decimal format.
   Important: This field has been expanded to four decimals to better represent frequencies of large datasets (e.g. where sample size > 1000 individuals)
* Phenotype Frequency: Percentage of individuals who have the allele or gene (Individuals / n).
* Allele Frequencies shown in green were calculated from Phenotype Frequencies assuming Hardy-Weinberg proportions.

¹ IMGT/HLA Database - For more details of the allele.
² Distribution - Graphical distribution of the allele.
³ Haplotype Association - Find HLA haplotypes with this allele.
ª Notes - See notes for ambiguous combinations of alleles.

Allele frequency net database (AFND) 2020 update: gold-standard data classification, open access genotype data and new query tools
Gonzalez-Galarza FF, McCabe A, Santos EJ, Jones J, Takeshita LY, Ortega-Rivera ND, Del Cid-Pavon GM, Ramsbottom K, Ghattaoraya GS, Alfirevic A, Middleton D and Jones AR Nucleic Acid Research 2020, 48:D783-8.
Liverpool, U.K.

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