Allele Frequencies in World Populations

HLA Database » Allele Report

The list below shows all populations in AFND that contains the allele. If an allele has an entry with a lower resolution this will be shown at the end.



Allele reported 139 time(s) and present in 75 population(s).

Population Phenotype
Frequency (%)
Distribution² Haplotype³
SENSenegal Dakar40.00.2110112See
GNBGuinea Bissau0.196065See
GMBGambia pop 331.90.1880939See
CPVCape Verde Southeastern Islands0.073062See
COLColombia San Basilio de Palenque0.060042See
CPVCape Verde Northwestern Islands0.024062See
ESPSpain Catalonia Girona0.024088See
CANCanada British Columbia Penutian0.019026See
USAUSA African American pop 70.0180193See
NICNicaragua Mestizo (G)3.20.0160155See
STPSao Tome Island Angolar0.016032See
USAUSA African American Bethesda2.80.0140187See
USAUSA NMDP African American pop 20.0139416581See
USAUSA Southern California Mestizo2.70.013573See
USAUSA African American pop 40.01312411See
USAUSA African American pop 30.0120564See
USAUSA NMDP African0.011428557See
USAUSA NMDP Caribean Indian0.010014339See
USAUSA Colorado Univ Cord Blood Bank African American0.0100261See
PRTPortugal Center0.010050See
ESPSpain Andalusia0.010099See
JORJordan Amman0.0100146See
MEXMexico Mixtec0.010097See
MEXMexico Oaxaca Jamiltepec Mixtec0.010096See
USAUSA NMDP Caribean Hispanic0.0090115374See
NICNicaragua Managua1.50.0075339See
USAUSA NMDP Caribean Black0.007033328See
MEXMexico Mexico City Mestizo population0.0070143See
CRICosta Rica Central Valley Mestizo (G)1.40.0070221See
USAUSA Hispanic pop 20.00601999See
GNQEquatorial Guinea Bioko Island Bubi0.0060100See
DZAAlgeria Oran0.0050100See
MARMorocco Nador Metalsa0.005099See
IRNIran Azeri0.0050100See
CRICosta Rica African -Caribbean (G)1.00.0050102See
USAUSA South Texas Hispanic0.0050194See
ESPSpain, Canary Islands, Gran canaria island0.90.0047215See
USAUSA NMDP Hispanic South or Central American0.0040146714See
USAUSA Philadelphia Caucasian0.70.0040141See
USAUSA Mexican American Mestizo0.0040553See
USAUSA Spain Ancestry0.0040279See
GTMGuatemala Mayan0.0040132See
ISRIsrael Ashkenazi Jews pop 20.0040132See
COLColombia Bogotá Cord Blood0.80.00381463See
USAUSA NMDP Mexican or Chicano0.0033261235See
USAUSA Colorado Univ Cord Blood Bank Hispanic0.00301058See
USAUSA Caucasian Pittsburgh0.60.0030177See
ENGEngland pop 60.60.0030177See
MEXMexico Highlands Mestizos0.60.0030160See
MEXMexico Mexico City Mestizo pop 20.0021234See
USAUSA Italy Ancestry0.0020273See
USAUSA Caucasian pop 50.0020268See
MEXMexico Mexico City Tlalpan0.30.0015330See
BRABrazil Rio de Janeiro Caucasian0.0010521See
USAUSA San Diego0.20.0010496See
USAUSA NMDP American Indian South or Central America0.00105926See
CHESwitzerland Lugano0.00091169See
USAUSA NMDP North American Amerindian0.000635791See
ESPSpain (Catalunya, Navarra, Extremadura, Aaragón, Cantabria,0.10.00054335See
DEUGermany DKMS - Spain minority0.00051107See
USAUSA Colorado Univ Cord Blood Bank Caucasian0.00043830See
SAUSaudi Arabia pop 6 (G)0.000128927See
USAUSA NMDP European Caucasian0.00011242890See
ISRIsrael Morocco Jews0.000136718See
USAUSA NMDP Filipino0.000150614See
USAUSA NMDP Hawaiian or other Pacific Islander0.000111499See
USAUSA NMDP Middle Eastern or North Coast of Africa0.000170890See
USAUSA NMDP Southeast Asian0.000027978See
DEUGermany DKMS - German donors0.00003456066See
USAUSA NMDP Chinese0.000099672See
USAUSA NMDP South Asian Indian0.0000185391See
USAUSA Alaska Yupik0.0000252See
USAUSA Colorado Univ Cord Blood Bank Asian0.0000100See
STPSao Tome Island Forro0.000066See
USAUSA Caucasian0.00.000061655See
USAUSA San Antonio Caucasian0.0000222See
PRTPortugal North0.000046See
PRTPortugal South0.000049See
PRYParaguay Lengua0.000017See
NIRIreland Northern0.00.00001000See
NLDNetherlands Leiden0.00001305See
USAUSA Caucasian Houston0.00.0000194See
USAUSA Asian pop 20.00001772See
USAUSA Caucasian pop 40.00001070See
USAUSA Caucasian Bethesda0.00.0000307See
DEUGermany pop 80.000039689See
CZECzech Republic0.0000106See
CAFCentral African Republic Aka Pygmy0.00.000093See
CANCanada British Columbia Athabaskan0.000062See
CHESwitzerland Aargau-Solothurn0.00001838See
CHESwitzerland Bern0.00003545See
CHESwitzerland Basel0.00001888See
CHESwitzerland Geneva pop 20.00001267See
CHESwitzerland Graubunden0.0000759See
CHESwitzerland Lausanne0.0000993See
CHESwitzerland Luzern0.00001553See
CHESwitzerland St Gallen0.00002113See
CHESwitzerland Sion0.0000832See
CHESwitzerland Zurich0.00004875See
CHNChina Urumqi Han0.000059See
CHNChina Urumqi Kazak0.000042See
CHNChina Urumqi Uyghur0.00.000057See
CODCongo Kinshasa Bantu0.00.000090See
COLColombia Bogota and Medellin Mestizo0.000065See
ARGArgentina Rio Negro Mapuche0.000034See
ARGArgentina Chubut Tehuelche0.000023See
ARGArgentina Salta Wichi0.000024See
BRABrazil Guarani Nandeva0.000086See
BRABrazil North East Mixed0.0000205See
BRABrazil Kaingang0.0000235See
BRABrazil Guarani M bya0.000093See
BRABrazil Southeast Caucasian0.00.0000103See
BRABrazil Southeast Mixed Race0.00.000042See
BRABrazil South Caucasian0.000073See
BRABrazil Vale do Ribeira Quilombos0.00.0000144See
ITAItaly Rome0.00.0000100See
ITAItaly North pop 30.00.000097See
ITAItaly Bergamo0.00.0000101See
ITAItaly pop 50.0000975See
IRNIran Kurd0.0000100See
ISRIsrael Moroccan Jews0.0000113See
KORSouth Korea pop 30.0000485See
MKDMacedonia pop 10.0000158See
MARMorocco Settat Chaouya0.000098See
FRAFrance West0.00.0000100See
FRAFrance Rennes pop 30.0000200See
ESPSpain Barcelona0.00.0000941See
ESPSpain Murcia0.0000173See
ISRIsrael Libyan Jews0.0000119See
ISRIsrael Iranian Jews0.0000101See
ISRIsrael Ethiopian Jews0.0000122See
ISRIsrael Yemenite Jews0.000076See
ISRIsrael Arab0.0000109See

Frequency data at lower resolution for this allele can be found in links below

Allele  Number of Populations 


* Allele Frequency: Total number of copies of the allele in the population sample (Alleles / 2n) in decimal format.
   Important: This field has been expanded to four decimals to better represent frequencies of large datasets (e.g. where sample size > 1000 individuals)
* Phenotype Frequency: Percentage of individuals who have the allele or gene (Individuals / n).
* Allele Frequencies shown in green were calculated from Phenotype Frequencies assuming Hardy-Weinberg proportions.

¹ IMGT/HLA Database - For more details of the allele.
² Distribution - Graphical distribution of the allele.
³ Haplotype Association - Find HLA haplotypes with this allele.
ª Notes - See notes for ambiguous combinations of alleles.


Allele frequency net database (AFND) 2020 update: gold-standard data classification, open access genotype data and new query tools
Gonzalez-Galarza FF, McCabe A, Santos EJ, Jones J, Takeshita LY, Ortega-Rivera ND, Del Cid-Pavon GM, Ramsbottom K, Ghattaoraya GS, Alfirevic A, Middleton D and Jones AR Nucleic Acid Research 2020, 48:D783-8.
Liverpool, U.K.

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