Allele Frequencies in World Populations

HLA Database » Allele Report

The list below shows all populations in AFND that contains the allele. If an allele has an entry with a lower resolution this will be shown at the end.



Allele reported 206 time(s) and present in 151 population(s).

Population Phenotype
Frequency (%)
Distribution² Haplotype³
ISRIsrael Georgia Jews0.07744471See
ISRIsrael USA Jews0.04736058See
ISRIsrael Poland Jews0.038413871See
ISRIsrael Ashkenazi Jews pop 30.03704625See
ISRIsrael Argentina Jews0.03444307See
ISRIsrael Ashkenazi Jews pop 20.0310132See
BRABrazil Ticuna0.031050See
ISRIsrael Bukhara Jews0.02732317See
ISRIsrael USSR Jews0.024045681See
ISRIsrael Druze0.02345914See
ISRIsrael Moroccan Jews0.0220113See
HRVCroatia Krk Island Dubasnica0.022023See
IRNIran Azeri0.0200100See
ISRIsrael Iranian Jews0.0200101See
HRVCroatia Krk Island0.0190212See
CANCanada British Columbia Penutian0.019026See
ISRIsrael Morocco Jews0.018836718See
LBNLebanon Kafar Zubian0.016094See
ISRIsrael Libya Jews0.01593739See
ARMArmenia combined Regions0.0150100See
ISRIsrael Iraq Jews0.012713270See
MEXMexico Nuevo Leon Mestizo2.50.012040See
PERPeru Lamas City Lama0.012083See
BRABrazil Southeast Mixed Race2.40.012042See
CHNChina Urumqi Kazak0.012042See
GAZGaza Palestinians0.0120165See
ISRIsrael Tunisia Jews0.01189070See
PRTPortugal North0.011046See
ISRIsrael Kavkazi Jews0.00922840See
MKDMacedonia pop 30.0090172See
ESPSpain Barcelona1.90.0090941See
USAUSA Mexican American Mestizo pop 30.0090116See
PRTAzores Central Islands0.009059See
RUSRussia Siberia Eskimo0.009070See
IRNIran Saqqez-Baneh Kurds0.008360See
IRNIran Yazd Zoroastrian0.008065See
ISRIsrael Libyan Jews0.0080119See
IRNIran Kurd pop 20.008060See
ENGEngland pop 61.70.0080177See
FRAFrance Southeast1.50.0080130See
GRCGreece pop21.60.0080120See
ISRIsrael Arab pop 20.007812301See
NICNicaragua Managua1.20.0075339See
IRNIran Fars Parsi0.007073See
ISRIsrael Yemenite Jews0.007076See
USAUSA Southern California Mestizo1.40.007073See
USAUSA Colorado Univ Cord Blood Bank Hispanic0.00701058See
ECUEcuadorean Amerindians0.006775See
GRCGreece pop 60.0062242See
BOLBolivia La Paz Aymaras0.006087See
MKDMacedonia pop 20.006080See
LBNLebanon Yuhmur0.006082See
USAUSA Caucasian Pittsburgh1.20.0060177See
MEXMexico Chihuahua Chihuahua City Pop 21.10.005788See
IRNIran Tabriz Azeris0.005297See
IRNIran Kurd0.0050100See
ISRIsrael Arab0.0050109See
ITAItaly Rome1.00.0050100See
MEXMexico Guanajuato and Jalisco Mestizo1.00.0050101See
NZLNew Zealand Maori0.0050200See
ARGArgentina Buenos Aires1.00.0050466See
FRAFrance West1.00.0050100See
ESPSpain Andalusia0.005099See
COLColombia Barranquilla0.0050188See
CZECzech Republic0.0050106See
TUNTunisia pop 30.0050104See
DEUGermany pop 30.90.0045111See
DEUGermany DKMS - Turkey minority0.00454856See
USAUSA NMDP Middle Eastern or North Coast of Africa0.004570890See
PRTPortugal Azores Terceira Island0.90.0044130See
USAUSA NMDP Mexican or Chicano0.0041261235See
SWESweden Southern Sami0.0040130See
PRTAzores Terceira Island0.0040130See
USAUSA Eastern European0.0040558See
USAUSA Caucasian pop 50.0040268See
GRCGreece Crete0.0040135See
GRCCretan Islanders0.0040124See
ESPSpain Granada0.0040280See
ISRIsrael Iran Jews0.00388153See
USAUSA NMDP Hispanic South or Central American0.0036146714See
MEXMexico Mexico City Mestizo population0.0035143See
CHESwitzerland Luzern0.00321553See
USAUSA Hispanic pop 20.00331999See
ESPSpain (Catalunya, Navarra, Extremadura, Aaragón, Cantabria,0.60.00314335See
DEUGermany Essen0.60.0030174See
LBNLebanon pop 20.0030191See
ITAItaly Central0.0030380See
ITAItaly pop 50.0030975See
USAUSA Caucasian Houston0.60.0030194See
CHLChile Santiago0.0030920See
HRVCroatia pop 40.00294000See
USAUSA Caucasian pop 40.00291070See
COLColombia Bogotá Cord Blood0.50.00271463See
DEUGermany DKMS - Spain minority0.00271107See
USAUSA NMDP European Caucasian0.00251242890See
DEUGermany DKMS - Italy minority0.00261159See
DEUGermany DKMS - Croatia minority0.00242057See
BRABrazil Paraná Caucasian0.50.0023641See
DEUGermany DKMS - Portugal minority0.00211176See
DEUGermany DKMS - Greece minority0.00211894See
MEXMexico Mexico City Mestizo pop 20.0021234See
DEUGermany pop 80.002039689See
GRCGreece pop30.40.0020246See
USAUSA NMDP American Indian South or Central America0.00205926See
TURTurkey pop 10.0020250See
USAUSA Caucasian0.40.002061655See
USAUSA San Francisco Caucasian0.0020220See
CHESwitzerland Lugano0.00191169See
DEUGermany pop 60.00198862See
DEUGermany DKMS - Austria minority0.00181698See
USAUSA NMDP Caribean Hispanic0.0017115374See
CZECzech Republic NMDR0.00175099See
CHESwitzerland Graubunden0.0017759See
DEUGermany DKMS - German donors0.00153456066See
MEXMexico Mexico City Tlalpan0.30.0015330See
POLPoland DKMS0.001420653See
CHESwitzerland Basel0.00131888See
SAUSaudi Arabia pop 6 (G)0.001328927See
CHESwitzerland Zurich0.00124875See
DEUGermany DKMS - Romania minority0.00121234See
USAUSA NMDP Hawaiian or other Pacific Islander0.001111499See
DEUGermany DKMS - France minority0.00111406See
CHESwitzerland Aargau-Solothurn0.00111838See
CHESwitzerland Bern0.00113545See
NLDNetherlands Leiden0.00101305See
USAUSA NMDP Alaska Native or Aleut0.00101376See
USAUSA San Diego0.20.0010496See
USAUSA NMDP Caribean Indian0.001014339See
USAUSA Colorado Univ Cord Blood Bank Caucasian0.00103830See
RUSRussia Karelia0.00091075See
CHESwitzerland Sion0.0009832See
USAUSA NMDP North American Amerindian0.000935791See
DEUGermany DKMS - Netherlands minority0.00071374See
DEUGermany DKMS - United Kingdom minority0.00051043See
DEUGermany DKMS - Bosnia and Herzegovina minority0.00051028See
USAUSA African American pop 40.00042411See
USAUSA NMDP Caribean Black0.000433328See
USAUSA NMDP African American pop 20.0003416581See
USAUSA NMDP African0.000328557See
USAUSA NMDP Southeast Asian0.000327978See
USAUSA NMDP Filipino0.000350614See
ISRIsrael YemenJews0.000215542See
TWNTaiwan Tzu Chi Morrow Donor Registry0.000146682See
USAUSA NMDP Japanese0.000024582See
USAUSA NMDP South Asian Indian0.0000185391See
USAUSA NMDP Vietnamese0.000043540See
USAUSA NMDP Chinese0.000099672See
TWNTaiwan Tzu Chi Morrow Donor Registry Aborigine0.0000233See
USAUSA San Antonio Caucasian0.0000222See
USAUSA South Texas Hispanic0.0000194See
USAUSA Alaska Yupik0.0000252See
USAUSA Colorado Univ Cord Blood Bank African American0.0000261See
USAUSA Colorado Univ Cord Blood Bank Asian0.0000100See
RUSRussia Siberia Chukchi0.000071See
PRTAzores Oriental Islands0.000043See
PRYParaguay Lengua0.000017See
USAUSA Asian pop 20.00001772See
USAUSA Philadelphia Caucasian0.00.0000141See
USAUSA Caucasian Bethesda0.00.0000307See
USAUSA African American Bethesda0.00.0000187See
ZAFSouth Africa Limpopo Venda0.0000117See
ITAItaly North pop 30.00.000097See
ITAItaly Bergamo0.00.0000101See
INDIndia North0.00.000085See
ISRIsrael Ethiopian Jews0.0000122See
PRTPortugal Center0.000050See
PRTPortugal South0.000049See
MKDMacedonia pop 10.0000158See
NIRIreland Northern0.00.00001000See
MNGMongolia Hoton0.000085See
MNGMongolia Khalkha pop 20.0000202See
MEXMexico Highlands Mestizos0.00.0000160See
LBNLebanon Niha el Shouff0.000061See
JPNJapan Hyogo Osaka and Nagano0.0000195See
KORSouth Korea pop 20.00.0000207See
KORSouth Korea pop 30.0000485See
MARMorocco Nador Metalsa0.000099See
MARMorocco Settat Chaouya0.000098See
ESPSpain Murcia0.0000173See
CHNChina Urumqi Han0.000059See
CHNChina Urumqi Uyghur0.00.000057See
CHNChina Harbin Manchu0.0000172See
CHNChina Harbin Korean0.0000201See
CODCongo Kinshasa Bantu0.00.000090See
COLColombia Bogota and Medellin Mestizo0.000065See
CHESwitzerland Geneva pop 20.00001267See
CHESwitzerland Lausanne0.0000993See
CHESwitzerland St Gallen0.00002113See
CAFCentral African Republic Aka Pygmy0.00.000093See
CANCanada British Columbia Athabaskan0.000062See
BRABrazil Vale do Ribeira Quilombos0.00.0000144See
ARGArgentina Rio Negro Mapuche0.000034See
ARGArgentina Chubut Tehuelche0.000023See
ARGArgentina Salta Wichi0.000024See
BRABrazil Guarani Nandeva0.000086See
BRABrazil North East Mixed0.0000205See
BRABrazil Kaingang0.0000235See
BRABrazil Guarani M bya0.000093See
BRABrazil Southeast Caucasian0.00.0000103See

Frequency data at lower resolution for this allele can be found in links below

Allele  Number of Populations 


* Allele Frequency: Total number of copies of the allele in the population sample (Alleles / 2n) in decimal format.
   Important: This field has been expanded to four decimals to better represent frequencies of large datasets (e.g. where sample size > 1000 individuals)
* Phenotype Frequency: Percentage of individuals who have the allele or gene (Individuals / n).
* Allele Frequencies shown in green were calculated from Phenotype Frequencies assuming Hardy-Weinberg proportions.

¹ IMGT/HLA Database - For more details of the allele.
² Distribution - Graphical distribution of the allele.
³ Haplotype Association - Find HLA haplotypes with this allele.
ª Notes - See notes for ambiguous combinations of alleles.


Allele frequency net database (AFND) 2020 update: gold-standard data classification, open access genotype data and new query tools
Gonzalez-Galarza FF, McCabe A, Santos EJ, Jones J, Takeshita LY, Ortega-Rivera ND, Del Cid-Pavon GM, Ramsbottom K, Ghattaoraya GS, Alfirevic A, Middleton D and Jones AR Nucleic Acid Research 2020, 48:D783-8.
Liverpool, U.K.

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