Allele Frequencies in World Populations

HLA Database » Allele Report

The list below shows all populations in AFND that contains the allele. If an allele has an entry with a lower resolution this will be shown at the end.



Allele reported 336 time(s) and present in 226 population(s).

Population Phenotype
Frequency (%)
Distribution² Haplotype³
CZECzech Republic Romani29.40.159734See
INDIndia North pop 20.130072See
CHNChina Yunnan Province Lisu0.1250111See
CHNChina Yunnan Hani0.1170150See
ESPSpain Andalusia Romani0.117099See
LKASri Lanka Colombo19.90.1090714See
MYSMalaysia Kedah Baling Kensiu0.100025See
MYSMalaysia Kedah Kensiu19.10.095021See
CHNChina Yunnan Province Bai0.0940128See
INDIndia Central UCBB18.40.09194204See
INDIndia West UCBB17.00.08505829See
INDIndia North UCBB16.50.08225849See
INDIndia East UCBB16.30.08162403See
INDIndia Northeast UCBB16.20.0811296See
MYSMalaysia Patani16.00.080025See
ISRIsrael Druze0.07985914See
INDIndia South UCBB15.90.079611446See
INDIndia Tamil Nadu0.07662492See
INDIndia Delhi0.0740112See
CHNChina Lijiang Naxi0.0740100See
MYSMalaysia Peninsular Indian14.40.0738271See
USAUSA NMDP South Asian Indian0.0713185391See
CHNChina Yunnan Province Wa0.0670119See
ISRIsrael Bukhara Jews0.05412317See
USAUSA NMDP Southeast Asian0.053427978See
CHNChina Yunnan Province Nu0.0500107See
INDIndia Andhra Pradesh Golla0.0500111See
CHNChina Yunnan Province Naxi0.0470118See
ISRIsrael Iraq Jews0.046313270See
CHNChina Yunnan Province Lahu0.045070See
INDIndia Northeast Lachung0.043058See
CHNChina Wanwei, Wutou and Shanxin Islands Jing0.0400138See
ISRIsrael Tunisia Jews0.03789070See
MYSMalaysia Mandailing7.40.037027See
SGPSingapore Riau Malay0.0370132See
THAThailand North Dai Lue0.036096See
INDIndia North7.00.035685See
IDNIndonesia Java0.034058See
INDIndia Northeast Mech0.032063See
CHNChina Southwest Dai0.0320124See
LBNLebanon Kafar Zubian0.032094See
THAThailand Kamphaeng Phet0.031097See
IDNIndonesia Nusa Tenggara Islands0.030049See
MYSMalaysia Peninsular Malay5.80.0294951See
CHNChina Harbin Manchu0.0290172See
THAThailand Northeast pop 20.0280400See
THAThailand Northeast0.027066See
CHNChina Yunnan Province Han pop 20.0270129See
INDIndia Mumbai Maratha0.027091See
MNGMongolia Ulaanbaatar Khalkha0.024041See
CHNChina, Xinjiang Uyghur Autonomous Region Uyghur4.40.021771See
CHNChina Jingpo Minority4.10.0210105See
USAUSA Asian pop 20.02041772See
AREUnited Arab Emirates Pop 10.0200570See
IDNIndonesia Singaporean0.020050See
INDIndia Northeast Rajbanshi0.020098See
GRCGreece pop24.10.0200120See
MYSMalaysia Perak Grik Jehai0.020025See
THAThailand Bangkok pop 20.020050See
PHLPhilippines Ivatan4.00.020050See
ISRIsrael Libya Jews0.01933739See
THAThailand Bangkok pop 30.0190187See
USAUSA Philippines0.0190105See
GRCGreece pop 83.60.018183See
MYSMalaysia Sabah Kadazan0.018057See
MYSMalaysia Kelantan3.60.018028See
VNMVietnam Hanoi Kinh pop 20.0180170See
MYSMalaysia Champa3.50.017029See
INDIndia Lucknow3.30.0170123See
IDNIndonesia Sundanese and Javanese0.0170201See
IDNIndonesia Java Western3.40.0170236See
ZAFSouth Africa Worcester3.00.0160159See
IDNIndonesia Java pop 20.014036See
USAUSA NMDP Filipino0.013150614See
IDNIndonesia Moluccan Islands0.013024See
MYSMalaysia Pahang Semai2.60.013038See
USAUSA NMDP Vietnamese0.013043540See
MKDMacedonia pop 20.012080See
MYSMalaysia Peninsular Chinese2.10.0103194See
MYSMalaysia Sarawak Iban0.010051See
TWNTaiwan Bunun pop 20.010050See
TUNTunisia pop 30.0100104See
RUSRussia Siberia Chukotka Peninsula Chukchi0.010059See
IRNIran Baloch0.0100100See
CHNChina Shandong Province Han0.010098See
VNMVietnam Hanoi Kinh0.0100103See
AREUnited Arab Emirates Abu Dhabi0.009652See
CHNChina Urumqi Uyghur1.80.009057See
CHNChina Guangxi Region Maonan0.0090108See
LBNLebanon Niha el Shouff0.009061See
DEUGermany DKMS - Romania minority0.00851234See
ISRIsrael Libyan Jews0.0080119See
CHNChina Yunnan Province Yao0.008066See
USAUSA NMDP Caribean Indian0.008014339See
DEUGermany DKMS - Greece minority0.00711894See
CHNChina Beijing Shijiazhuang Tianjian Han0.0070618See
HKGHong Kong Chinese BMDR0.00687595See
ECUEcuadorean Amerindians0.006775See
DEUGermany DKMS - Bosnia and Herzegovina minority0.00631028See
CHNChina Jiangsu Han0.00623238See
HKGHong Kong Chinese cord blood registry0.00603892See
GEOGeorgia Svaneti Region Svan0.006080See
CHNChina Guizhou Province Miao0.006085See
COKCook Islands Rarotonga0.006078See
CHNChina Beijing and Xian0.0060171See
MKDMacedonia pop 30.0060172See
PNGPapua New Guinea Trobriand Island0.006081See
RUSRussia Chuvash0.006082See
TURTurkey pop 10.0060250See
TWNTaiwan Han Chinese0.0060504See
ESPSpain Las Alpujarras0.005985See
CHNChina Hubei Han1.20.00583732See
DEUGermany DKMS - Turkey minority0.00574856See
USAUSA NMDP Hawaiian or other Pacific Islander0.005111499See
USAUSA NMDP Chinese0.005199672See
USAUSA South Dakota Sioux0.0050101See
USAUSA African American pop 70.0050193See
ZAFSouth Africa Caucasians0.0050102See
GRCGreece pop 40.005098See
CHNChina Xinjiang Province Uyghur0.005092See
ARMArmenia combined Regions0.0050100See
CHNChina Han Guandong Province0.0050208See
CHNChina Yunnan Province Jinuo0.0050109See
CHNChina Inner Mongolia Region Ewenki0.005094See
USAUSA Colorado Univ Cord Blood Bank Asian0.0050100See
TWNTaiwan Minnan pop 11.00.0050102See
NZLNew Zealand Maori with Admixed History1.00.0050105See
ITAItaly Central0.0050380See
ISRIsrael Arab0.0050109See
CHNChina Zhejiang Han pop 20.0048833See
DEUGermany DKMS - Italy minority0.00431159See
TWNTaiwan Tzu Chi Morrow Donor Registry Aborigine0.0043233See
GEOGeorgia Caucasus Tbilisi0.0042119See
SAUSaudi Arabia pop 6 (G)0.004128927See
USAUSA NMDP Middle Eastern or North Coast of Africa0.004170890See
USAUSA Spain Ancestry0.0040279See
USAUSA Philadelphia Caucasian0.70.0040141See
USAUSA Italy Ancestry0.0040273See
USAUSA NMDP American Indian South or Central America0.00405926See
USAUSA San Diego0.80.0040496See
FRAFrance Southeast0.80.0040130See
CHNChina Yunnan Bulang0.0040116See
CHNChina Jiangsu Province Han0.0035334See
DEUGermany DKMS - China minority0.00311282See
CHNChina Marrow Donor Registry0.0030600See
TWNTaiwan Minnan and Hakka0.0030190See
RUSRussia Northwest Slavic0.0030200See
INDIndia Northeast Shia0.0030190See
ITAItaly pop 50.0030975See
MKDMacedonia pop 10.0030158See
MEXMexico Mexico City Tlalpan0.60.0030330See
ESPSpain (Catalunya, Navarra, Extremadura, Aaragón, Cantabria,0.60.00294335See
DEUGermany DKMS - Croatia minority0.00272057See
CZECzech Republic NMDR0.00255099See
TWNTaiwan Tzu Chi Morrow Donor Registry0.002546682See
USAUSA NMDP Caribean Black0.002533328See
ISRIsrael Kavkazi Jews0.00232840See
GRCGreece pop 60.0021242See
GRCGreece pop30.40.0020246See
CHNChina Inner Mongolia Autonomous Region Northeast0.40.0020496See
CHESwitzerland Basel0.00201888See
ARGArgentina Buenos Aires0.50.0020466See
CHNChina Canton Han0.0020264See
TWNTaiwan pop 20.0020364See
USAUSA Eastern European0.0020558See
USAUSA Caucasian pop 50.0020268See
USAUSA San Francisco Caucasian0.0020220See
USAUSA African American pop 30.0020564See
CHESwitzerland St Gallen0.00192113See
ISRIsrael Arab pop 20.001812301See
USAUSA NMDP Caribean Hispanic0.0017115374See
TZATanzania Maasai0.30.0015336See
USAUSA Caucasian0.30.001561655See
NICNicaragua Managua0.30.0015339See
ENGEngland Bedfordshire0.30.0015354See
HRVCroatia pop 40.00154000See
RUSRussia Karelia0.00141075See
DEUGermany DKMS - France minority0.00141406See
CHESwitzerland Sion0.0013832See
CHESwitzerland Lausanne0.0012993See
USAUSA NMDP North American Amerindian0.001235791See
DEUGermany pop 80.001139689See
ESPSpain Barcelona0.20.0010941See
TWNTaiwan Tzu Chi Cord Blood Bank0.0010710See
NLDNetherlands Leiden0.00101305See
KORSouth Korea pop 60.0010800See
USAUSA NMDP Alaska Native or Aleut0.00101376See
USAUSA Colorado Univ Cord Blood Bank Hispanic0.00101058See
DEUGermany DKMS - Austria minority0.00091698See
DEUGermany DKMS - Portugal minority0.00091176See
POLPoland DKMS0.000920653See
USAUSA NMDP Hispanic South or Central American0.0008146714See
USAUSA NMDP European Caucasian0.00071242890See
DEUGermany DKMS - German donors0.00073456066See
DEUGermany DKMS - Netherlands minority0.00071374See
CHESwitzerland Luzern0.00071553See
CHESwitzerland Bern0.00063545See
DEUGermany pop 60.00068862See
USAUSA NMDP Korean0.000677584See
ISRIsrael Iran Jews0.00068153See
CHLChile Santiago0.0005920See
USAUSA NMDP African American pop 20.0005416581See
USAUSA NMDP African0.000528557See
ISRIsrael Morocco Jews0.000536718See
USAUSA African American pop 40.00042411See
USAUSA Colorado Univ Cord Blood Bank Caucasian0.00043830See
ISRIsrael Argentina Jews0.00034307See
COLColombia Bogotá Cord Blood0.10.00031463See
ISRIsrael USSR Jews0.000345681See
USAUSA NMDP Mexican or Chicano0.0003261235See
KORSouth Korea pop 100.00024128See
USAUSA Hispanic pop 20.00031999See
USAUSA NMDP Japanese0.000224582See
ISRIsrael Poland Jews0.000113871See
ISRIsrael Georgia Jews0.00014471See
ISRIsrael Ashkenazi Jews pop 30.00014625See
JPNJapan pop 160.000118604See
ISRIsrael USA Jews0.00016058See
ISRIsrael YemenJews0.000115542See
INDIndia Northeast Sunni0.0000188See
KORSouth Korea pop 20.00.0000207See
KORSouth Korea pop 30.0000485See
ITAItaly Rome0.00.0000100See
ITAItaly North pop 30.00.000097See
ITAItaly Bergamo0.00.0000101See
JPNJapan Hyogo Osaka and Nagano0.0000195See
MARMorocco Nador Metalsa0.000099See
MARMorocco Settat Chaouya0.000098See
MEXMexico Highlands Mestizos0.00.0000160See
MEXMexico Nuevo Leon Mestizo0.00.000040See
LBNLebanon Yuhmur0.000082See
MNGMongolia Tarialan Khoton0.000085See
MNGMongolia Hoton0.000085See
MNGMongolia Khalkha pop 20.0000202See
PNGPapua New Guinea Lowland0.000047See
PNGPapua New Guinea Lowland Wosera0.000079See
PNGPapua New Guinea Highland0.000094See
PNGPapua New Guinea East New Britain Tolai0.000048See
PNGPapua New Guinea Highland pop20.000028See
NIRIreland Northern0.00.00001000See
USAUSA San Antonio Caucasian0.0000222See
USAUSA South Texas Hispanic0.0000194See
USAUSA Alaska Yupik0.0000252See
USAUSA Colorado Univ Cord Blood Bank African American0.0000261See
TWNTaiwan Tsou pop 20.000050See
TWNTaiwan Paiwan pop 20.000050See
TWNTaiwan Rukai pop 20.000050See
TWNTaiwan Orchid Island Yami0.000050See
TWNTaiwan Ami pop 20.000050See
TWNTaiwan Pazeh0.00.000055See
TWNTaiwan Siraya0.00.000051See
TWNTaiwan Thao0.00.000030See
TWNTaiwan Aborigine pop 20.000048See
TWNTaiwan Atayal pop 20.000050See
TWNTaiwan Saisiat pop 20.000050See
TWNTaiwan Tsou0.00.000051See
TWNTaiwan Rukai0.00.000050See
TWNTaiwan Paiwan0.00.000051See
TWNTaiwan Ami0.00.000098See
TWNTaiwan Puyuma0.00.000050See
TWNTaiwan Tao0.00.000050See
PRYParaguay Lengua0.000017See
PNGPapua New Guinea Lowland Roro0.000026See
RUSRussia Siberia Sulamai Ket0.000022See
RUSRussia Siberia Polygus Evenk0.000035See
RUSRussia Siberia North East Kamchatka Koryak0.000092See
RUSRussia Siberia Gvaysugi Udege0.000025See
RUSRussia Siberia NW of Sakhalin Island Nivkh0.000032See
RUSRussia Siberia Chukotka Peninsula Eskimo0.000080See
SDNSudan Mixed0.00.0000200See
TWNTaiwan Puyuma pop 20.000050See
TWNTaiwan Han0.000050See
TWNTaiwan Hakka0.00.000055See
TWNTaiwan Atayal0.00.0000106See
TWNTaiwan Taroko0.00.000055See
TWNTaiwan Saisiat0.00.000051See
TWNTaiwan Bunun0.00.0000101See
CZECzech Republic0.0000106See
CZECzech Republic pop 20.00.000099See
COLColombia Bogota and Medellin Mestizo0.000065See
CODCongo Kinshasa Bantu0.00.000090See
CHNChina Harbin Korean0.0000201See
CHNChina Urumqi Kazak0.000042See
CHNChina Yunnan Province Drung0.000070See
ARGArgentina Salta Wichi0.000024See
ARGArgentina Rio Negro Mapuche0.000034See
ARGArgentina Chubut Tehuelche0.000023See
BORBorneo Bandjarmasin0.000021See
BRABrazil North East Mixed0.0000205See
BRABrazil Kaingang0.0000235See
BRABrazil Guarani M bya0.000093See
BRABrazil Southeast Caucasian0.00.0000103See
BRABrazil Southeast Mixed Race0.00.000042See
BRABrazil Mato Grosso do Sul0.0000203See
CAFCentral African Republic Aka Pygmy0.00.000093See
CANCanada British Columbia Athabaskan0.000062See
CANCanada British Columbia Penutian0.000026See
CHESwitzerland Aargau-Solothurn0.00001838See
CHESwitzerland Zurich0.00004875See
CHESwitzerland Geneva pop 20.00001267See
CHESwitzerland Graubunden0.0000759See
CHESwitzerland Lugano0.00001169See
CHNChina Urumqi Han0.000059See
CHNChina Hong Kong and Singapore0.0000135See
DEUGermany pop 30.00.0000111See
ESPSpain Murcia0.0000173See
FRAFrance West0.00.0000100See
FRAFrance Rennes0.0000200See
IDNIndonesia Java Yogyakarta Region0.000062See
INDIndia Northeast Kayastha0.0000190See
ISRIsrael Iranian Jews0.0000101See
ISRIsrael Ethiopian Jews0.0000122See
ISRIsrael Yemenite Jews0.000076See
INDIndia Northeast Mathur0.0000155See
INDIndia Northeast Rastogi0.0000196See
INDIndia Northeast Vaish0.0000198See
USAUSA Caucasian Houston0.00.0000194See
USAUSA Caucasian Pittsburgh0.00.0000177See
USAUSA Caucasian Bethesda0.00.0000307See
USAUSA African American Bethesda0.00.0000187See
WSMWestern Samoa and Tokelau0.000051See
WSMSamoa West0.000022See

Frequency data at lower resolution for this allele can be found in links below

Allele  Number of Populations 


* Allele Frequency: Total number of copies of the allele in the population sample (Alleles / 2n) in decimal format.
   Important: This field has been expanded to four decimals to better represent frequencies of large datasets (e.g. where sample size > 1000 individuals)
* Phenotype Frequency: Percentage of individuals who have the allele or gene (Individuals / n).
* Allele Frequencies shown in green were calculated from Phenotype Frequencies assuming Hardy-Weinberg proportions.

¹ IMGT/HLA Database - For more details of the allele.
² Distribution - Graphical distribution of the allele.
³ Haplotype Association - Find HLA haplotypes with this allele.
ª Notes - See notes for ambiguous combinations of alleles.


Allele frequency net database (AFND) 2020 update: gold-standard data classification, open access genotype data and new query tools
Gonzalez-Galarza FF, McCabe A, Santos EJ, Jones J, Takeshita LY, Ortega-Rivera ND, Del Cid-Pavon GM, Ramsbottom K, Ghattaoraya GS, Alfirevic A, Middleton D and Jones AR Nucleic Acid Research 2020, 48:D783-8.
Liverpool, U.K.

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