Allele Frequencies in World Populations

HLA Database Allele Report

The list below shows all populations in AFND that contains the allele. If an allele has an entry with a lower resolution this will be shown at the end.



Allele reported 257 time(s) and present in 162 population(s).

Population Phenotype
Frequency (%)
Distribution² Haplotype³
TWNTaiwan Taroko21.80.127055See
TWNTaiwan Atayal pop 20.110050See
TWNTaiwan Puyuma pop 20.100050See
TWNTaiwan Tsou pop 20.080050See
TWNTaiwan Puyuma12.00.060050See
TWNTaiwan Tsou7.80.049051See
CHNChina Harbin Manchu0.0470172See
KORSouth Korea pop 49.00.0460211See
JPNJapan Nagano8.80.045057See
TWNTaiwan Atayal8.50.0420106See
KORSouth Korea pop 27.70.0390207See
RUSRussia Sakhalin Island Nivkhi0.038053See
CHNChina, Xinjiang Uyghur Autonomous Region Han7.50.037570See
TWNTaiwan Pazeh5.50.036055See
JPNJapan Hokkaido Wajin7.00.035671See
KORSouth Korea pop 30.0350485See
TWNTaiwan Bunun6.90.0350101See
RUSRussia Tuva pop30.034044See
KORSouth Korea pop 110.0340149See
TWNTaiwan Thao6.70.033030See
KORSouth Korea pop 60.0320800See
USAUSA NMDP Korean0.031677584See
TWNTaiwan Aborigine pop 20.031048See
JPNJapan Hyogo6.30.031032See
TWNTaiwan Tao6.00.030050See
TWNTaiwan Ami pop 20.030050See
TWNTaiwan Saisiat pop 20.030050See
THAThailand Bangkok pop 20.030050See
KORSouth Korea pop 10.0290324See
KORSouth Korea pop 100.02804128See
JPNJapan Hyogo Osaka and Nagano0.0280195See
TWNTaiwan Tzu Chi Morrow Donor Registry Aborigine0.0279233See
JPNJapan pop 20.0260916See
MYSMalaysia Peninsular Chinese5.20.0258194See
TWNTaiwan Tzu Chi Morrow Donor Registry0.024446682See
JPNJapan pop 114.80.024362See
USAUSA NMDP Japanese0.024224582See
DEUGermany DKMS - China minority0.02421282See
CHNChina Jiangsu Province Han0.0240334See
JPNJapan pop 64.70.0237129See
TWNTaiwan pop10.0230539See
USAUSA NMDP Chinese0.022899672See
TWNTaiwan Han Chinese0.0220504See
JPNJapan pop 30.02201018See
CHNChina Hong Kong and Singapore0.0220135See
CHNChina Harbin Korean0.0220201See
CHNChina, Xinjiang Uyghur Autonomous Region Uyghur4.40.021771See
JPNJapan Kyoto and Osaka0.0210165See
TWNTaiwan Tzu Chi Cord Blood Bank0.0210710See
JPNJapan pop 160.020918604See
CHNChina Hubei Han4.20.02093732See
HKGHong Kong Chinese BMDR0.02057595See
CHNChina Jiangsu Han0.02013238See
CHNChina Yunnan Hani0.0200150See
INDIndia Northeast Rajbanshi0.020098See
TWNTaiwan Siraya3.90.020051See
CHNChina Canton Han0.0190264See
HKGHong Kong Chinese cord blood registry0.01893892See
CHNChina Beijing Shijiazhuang Tianjian Han0.0180618See
CHNChina Urumqi Uyghur3.50.018057See
CHNChina Yunnan Province Lahu0.018070See
CHNChina Wanwei, Wutou and Shanxin Islands Jing0.0180138See
TWNTaiwan Hakka3.60.018055See
USAUSA Asian pop 20.01751772See
CHNChina Marrow Donor Registry0.0170600See
INDIndia Northeast Lachung0.017058See
JPNJapan pop 43.40.0170525See
JPNJapan pop 170.01693078See
INDIndia Northeast Mech0.016063See
THAThailand Kamphaeng Phet0.016097See
CHNChina Jiangxi Province0.015098See
CHNChina Shandong Province Han0.015098See
CHNChina Zhejiang Han pop 20.0144833See
CHNChina Guangxi Region Maonan0.0140108See
CHNChina Beijing and Xian0.0120171See
CHNChina Southwest Dai0.0120124See
CHNChina Urumqi Kazak0.012042See
VNMVietnam Hanoi Kinh pop 20.0120170See
JPNJapan Central0.0110371See
JPNJapan Aichi2.20.011050See
RUSRussia Tuva pop 20.0110169See
PHLPhilippines Ivatan2.00.010050See
PNGPapua New Guinea Rual0.010050See
IRNIran Kurd0.0100100See
TWNTaiwan Bunun pop 20.010050See
TWNTaiwan Saisiat2.00.010051See
TWNTaiwan Minnan pop 12.00.0100102See
USAUSA NMDP Vietnamese0.009043540See
RUSRussia Siberia Eskimo0.009070See
MYSMalaysia Sabah Kadazan0.009057See
CHNChina Yunnan Province Naxi0.0090118See
CHNChina Urumqi Han0.008059See
RUSRussia Tuva0.0080190See
IRNIran Gorgan0.008064See
JPNJapan South1.60.0080125See
STPSao Tome Island Forro0.008066See
TWNTaiwan pop 20.0080364See
USAUSA Southern California Mestizo1.40.007073See
IRNIran Fars Parsi0.007073See
USAUSA NMDP Filipino0.006550614See
USAUSA San Diego1.20.0060496See
IDNIndonesia Nusa Tenggara Islands0.006049See
PNGPapua New Guinea Highland0.006094See
USAUSA NMDP Hawaiian or other Pacific Islander0.006011499See
USAUSA Colorado Univ Cord Blood Bank Asian0.0050100See
VNMVietnam Hanoi Kinh0.0050103See
THAThailand North Dai Lue0.005096See
NZLNew Zealand Maori with Admixed History1.00.0050105See
MNGMongolia Khalkha pop 20.0050202See
CHNChina Lijiang Naxi0.0050100See
CHNChina Yunnan Province Nu0.0050107See
CHNChina Yunnan Province Han0.0050101See
CHNChina pop11.00.0050103See
CHNChina Yunnan Province Bai0.0040128See
CHNChina Yunnan Province Han pop 20.0040129See
THAThailand Northeast pop 20.0040400See
THAThailand Northeast0.004066See
USAUSA NMDP Southeast Asian0.003827978See
USAUSA Caucasian Houston0.60.0030194See
RUSRussia Northwest Slavic0.0030200See
INDIndia West UCBB0.50.00235829See
INDIndia East UCBB0.50.00232403See
USAUSA San Francisco Caucasian0.0020220See
INDIndia Central UCBB0.40.00184204See
INDIndia North UCBB0.30.00175849See
INDIndia Northeast UCBB0.30.0017296See
MYSMalaysia Peninsular Malay0.30.0016951See
DEUGermany DKMS - Turkey minority0.00144856See
USAUSA NMDP South Asian Indian0.0009185391See
INDIndia South UCBB0.20.000711446See
DEUGermany DKMS - Croatia minority0.00072057See
CHLChile Santiago0.0005920See
RUSRussia Karelia0.00051075See
DEUGermany DKMS - Spain minority0.00051107See
CZECzech Republic NMDR0.00035099See
SAUSaudi Arabia pop 6 (G)0.000228927See
INDIndia Tamil Nadu0.00022492See
DEUGermany pop 80.000239689See
CHESwitzerland Bern0.00023545See
USAUSA Hispanic pop 20.00031999See
USAUSA Colorado Univ Cord Blood Bank Caucasian0.00013830See
POLPoland DKMS0.000220653See
HRVCroatia pop 40.00014000See
USAUSA NMDP Middle Eastern or North Coast of Africa0.000170890See
ISRIsrael Tunisia Jews0.00019070See
USAUSA NMDP Hispanic South or Central American0.0001146714See
USAUSA NMDP Caribean Hispanic0.0000115374See
ISRIsrael Arab pop 20.000012301See
DEUGermany DKMS - German donors0.00003456066See
ISRIsrael Poland Jews0.000013871See
ISRIsrael USSR Jews0.000045681See
USAUSA NMDP Mexican or Chicano0.0000261235See
USAUSA NMDP Caribean Black0.000033328See
USAUSA NMDP European Caucasian0.00001242890See
USAUSA NMDP African American pop 20.0000416581See
USAUSA NMDP African0.000028557See
USAUSA NMDP North American Amerindian0.000035791See
ISRIsrael Morocco Jews0.000036718See
IRNIran Yazd Zoroastrian0.000065See
IRNIran Azeri0.0000100See
NIRIreland Northern0.00.00001000See
IDNIndonesia Moluccan Islands0.000024See
IDNIndonesia Singaporean0.000050See
IDNIndonesia Java Yogyakarta Region0.000062See
ITAItaly pop 50.0000975See
ITAItaly Rome0.00.0000100See
ITAItaly North pop 30.00.000097See
ITAItaly Bergamo0.00.0000101See
PNGPapua New Guinea Lowland0.000047See
PNGPapua New Guinea Lowland Wosera0.000079See
PNGPapua New Guinea Highland pop20.000028See
PNGPapua New Guinea East New Britain Tolai0.000048See
PRYParaguay Lengua0.000017See
MARMorocco Nador Metalsa0.000099See
MARMorocco Settat Chaouya0.000098See
NLDNetherlands Leiden0.00001305See
MEXMexico Highlands Mestizos0.00.0000160See
MEXMexico Nuevo Leon Mestizo0.00.000040See
MNGMongolia Hoton0.000085See
DEUGermany pop 60.00018862See
CZECzech Republic0.0000106See
ENGEngland pop 60.00.0000177See
FRAFrance West0.00.0000100See
COLColombia Bogota and Medellin Mestizo0.000065See
CODCongo Kinshasa Bantu0.00.000090See
COKCook Islands Rarotonga0.000078See
INDIndia Northeast Kayastha0.0000190See
INDIndia Northeast Mathur0.0000155See
INDIndia Northeast Rastogi0.0000196See
INDIndia Northeast Vaish0.0000198See
INDIndia Northeast Shia0.0000190See
INDIndia Northeast Sunni0.0000188See
ARGArgentina Rio Negro Mapuche0.000034See
ARGArgentina Chubut Tehuelche0.000023See
ARGArgentina Salta Wichi0.000024See
BORBorneo Bandjarmasin0.000021See
BRABrazil North East Mixed0.0000205See
BRABrazil Kaingang0.0000235See
BRABrazil Southeast Caucasian0.00.0000103See
BRABrazil Southeast Mixed Race0.00.000042See
BRABrazil Guarani M bya0.000093See
CANCanada British Columbia Athabaskan0.000062See
CANCanada British Columbia Penutian0.000026See
CAFCentral African Republic Aka Pygmy0.00.000093See
CHNChina Yunnan Province Drung0.000070See
CHNChina Xinjiang Province Uyghur0.000092See
TWNTaiwan Han0.000050See
TWNTaiwan Rukai0.00.000050See
TWNTaiwan Paiwan0.00.000051See
TWNTaiwan Ami0.00.000098See
TWNTaiwan Paiwan pop 20.000050See
TWNTaiwan Rukai pop 20.000050See
TWNTaiwan Orchid Island Yami0.000050See
CHESwitzerland Basel0.00001888See
CHESwitzerland Geneva pop 20.00001267See
CHESwitzerland Graubunden0.0000759See
CHESwitzerland Lugano0.00001169See
CHESwitzerland Lausanne0.0000993See
CHESwitzerland Luzern0.00001553See
CHESwitzerland St Gallen0.00002113See
CHESwitzerland Sion0.0000832See
CHESwitzerland Zurich0.00004875See
ESPSpain Barcelona0.00.0000941See
ESPSpain Murcia0.0000173See
CHESwitzerland Aargau-Solothurn0.00001838See
STPSao Tome Island Angolar0.000032See
RUSRussia Siberia Chukchi0.000071See
RUSRussia Tuva Todja0.000022See
RUSRussia Siberia Irkutsk Tofalar0.000043See
RUSRussia Siberia Kushun Buryat0.000025See
RUSRussia Siberia Khanty Mansi0.000068See
RUSRussia Siberia Ulchi0.000073See
RUSRussia Siberia Negidal0.000035See
RUSRussia Siberia Khabarovsk Evenki0.000025See
WSMWestern Samoa and Tokelau0.000051See
WSMSamoa West0.000022See
USAUSA Alaska Yupik0.0000252See
USAUSA Caucasian0.00.000061655See
USAUSA San Antonio Caucasian0.0000222See
USAUSA South Texas Hispanic0.0000194See
USAUSA Caucasian Bethesda0.00.0000307See
USAUSA African American Bethesda0.00.0000187See
USAUSA Colorado Univ Cord Blood Bank Hispanic0.00001058See
USAUSA Caucasian Pittsburgh0.00.0000177See
USAUSA Colorado Univ Cord Blood Bank African American0.0000261See
USAUSA Philadelphia Caucasian0.00.0000141See
USAUSA African American pop 40.00002411See

Frequency data at lower resolution for this allele can be found in links below

Allele  Number of Populations 


* Allele Frequency: Total number of copies of the allele in the population sample (Alleles / 2n) in decimal format.
   Important: This field has been expanded to four decimals to better represent frequencies of large datasets (e.g. where sample size > 1000 individuals)
* Phenotype Frequency: Percentage of individuals who have the allele or gene (Individuals / n).
* Allele Frequencies shown in green were calculated from Phenotype Frequencies assuming Hardy-Weinberg proportions.

¹ IMGT/HLA Database - For more details of the allele.
² Distribution - Graphical distribution of the allele.
³ Haplotype Association - Find HLA haplotypes with this allele.
ª Notes - See notes for ambiguous combinations of alleles.

Allele frequency net database (AFND) 2020 update: gold-standard data classification, open access genotype data and new query tools
Gonzalez-Galarza FF, McCabe A, Santos EJ, Jones J, Takeshita LY, Ortega-Rivera ND, Del Cid-Pavon GM, Ramsbottom K, Ghattaoraya GS, Alfirevic A, Middleton D and Jones AR Nucleic Acid Research 2020, 48:D783-8.
Liverpool, U.K.

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