Allele Frequencies in World Populations

HLA Database » Allele Report

The list below shows all populations in AFND that contains the allele. If an allele has an entry with a lower resolution this will be shown at the end.



Allele reported 239 time(s) and present in 170 population(s).

Population Phenotype
Frequency (%)
Distribution² Haplotype³
PRYParaguay Lengua0.647017See
ARGArgentina Salta Wichi0.417024See
ARGArgentina Gran Chaco Western Toba Pilaga0.272019See
ARGArgentina Gran Chaco Eastern Toba0.2370135See
ARGArgentina Chiriguano33.90.196054See
ARGArgentina Rosario Toba37.20.192086See
MEXMexico Mixtec NA-DHS_5 (G)30.00.175020See
ARGArgentina Gran Chaco Mataco Wichi0.171049See
JPNJapan Hokkaido Ainu0.170050See
MEXMexico San Vicente Tancuayalab Teenek/Huastecos0.132153See
MEXMexico Huasteca Region Teenek0.130055See
MEXMexico Mixe NA-DHS_6 (G)20.00.125020See
MEXMexico Mazahua0.120065See
MEXMexico Jaltepec Mazahuas0.120050See
MEXMexico Sinaloa Capomos Mayo Yoremes0.116760See
BRABrazil Terena22.00.110060See
GTMGuatemala Kaqchikel NA-DHS_8 (G)21.10.105319See
MEXMexico Nahua/Aztec Santo Domingo Ocotitlan0.102773See
MEXMexico Mexico City Mestizo pop 20.1004234See
MEXMexico Oaxaca Mixtec0.0970103See
USAUSA New Mexico Zuni0.090051See
MEXMexico Nuevo Leon Mestizo17.50.089040See
MEXMexico Mazatecan0.084089See
MEXMexico Zapotec NA-DHS_7 (G)15.80.078920See
MEXMexico Oaxaca Mixe0.073055See
MEXMexico Mayan0.067016See
USAUSA Southern California Mestizo12.30.063573See
MEXMexico Highlands Mestizos11.90.0630160See
MEXMexico Oaxaca Zapotec0.063090See
MEXMexico Chihuahua Chihuahua City Pop 212.50.062588See
MEXMexico Guanajuato and Jalisco Mestizo11.90.0590101See
RUSRussia Sakhalin Island Nivkhi0.057053See
MEXMexico Mexico City Tlalpan11.20.0561330See
USAUSA South Texas Hispanic0.0560194See
MEXMexico Mexico City Mestizo pop 30.0530256See
BOLBolivia/Peru Quechua NA-DHS_12 (G)9.50.047621See
MEXMexico Oaxaca Jamiltepec Mixtec0.047096See
USAUSA Arizona Gila River Amerindian0.0470492See
MEXMexico Mixtec0.046097See
MEXMexico Mayan pop 20.0460163See
GTMGuatemala, Guatemala City Mixed Ancestry7.90.0433127See
USAUSA NMDP Mexican or Chicano0.0427261235See
MEXMexico Chichen Itza Maya (prehispanic)0.042647See
MEXMexico Mexico City Mestizo population0.0420143See
NICNicaragua Managua8.40.0419339See
COLColombia Zenu NA-DHS_18 (G)8.30.041716See
MEXMexico Chiapas Lacandon Mayans0.0390218See
USAUSA Colorado Univ Cord Blood Bank Hispanic0.03601058See
USAUSA Mexican American Mestizo0.0350553See
COLColombia Arhuaco NA-DHS_16 (G)5.90.029417See
USAUSA Arizona Pima pop20.029018See
JPNJapan Nagano5.30.026857See
USAUSA Hispanic pop 20.02551999See
JPNJapan Hyogo Osaka and Nagano0.0230195See
JPNJapan Hokkaido Wajin4.20.021271See
AUSAustralia Yuendumu Aborigine0.0210191See
JPNJapan Central0.0180371See
MEXMexico Veracruz Xalapa3.60.017984See
USAUSA NMDP Hispanic South or Central American0.0173146714See
BRABrazil Puyanawa3.30.0170150See
USAUSA Spain Ancestry0.0160279See
JPNJapan pop 63.10.0156129See
ISRIsrael Tunisia Jews0.01549070See
BOLBolivia Quechua0.014569See
ISRIsrael Libya Jews0.01443739See
USAUSA NMDP Japanese0.014224582See
ESPSpain Tenerife Island0.014083See
JPNJapan pop 20.0130916See
JPNJapan pop 160.013018604See
JPNJapan pop 30.01301018See
USAUSA New Mexico Canoncito Navajo0.013042See
JPNJapan Kyoto and Osaka0.0120165See
JPNJapan South2.40.0120125See
BRABrazil Southeast Mixed Race2.40.012042See
JPNJapan pop 170.01143078See
JPNJapan Aichi2.20.011050See
JPNJapan pop 42.10.0110525See
CHNChina Inner Mongolia Region Ewenki0.011094See
MEXMexico Chihuahua Tarahumara0.011044See
COLColombia North Chimila Amerindians0.010647See
CRICosta Rica and Panama Mestizo0.010056See
CHNChina Harbin Korean0.0100201See
MARMorocco Settat Chaouya0.010098See
MARMorocco Atlantic Coast Chaouya0.010098See
PNGPapua New Guinea Rual0.010050See
PNGPapua New Guinea Wonie0.010051See
USAUSA San Diego1.80.0090496See
PRTPortugal Azores Terceira Island1.80.0088130See
PNGPapua New Guinea Dorogori0.008059See
KORSouth Korea pop 30.0080485See
KORSouth Korea pop 60.0080800See
KORSouth Korea pop 10.0080324See
CHLChile Mapuche0.007766See
MEXMexico Tixcacaltuyub Maya0.007567See
KORSouth Korea pop 41.40.0070211See
CHNChina Yunnan Province Drung0.007070See
RUSRussia Siberia Ulchi0.007073See
USAUSA NMDP American Indian South or Central America0.00705926See
BRABrazil South Caucasian0.006973See
USAUSA NMDP Korean0.006877584See
KORSouth Korea pop 100.00554128See
MARMorocco Nador Metalsa0.005099See
ARGArgentina Buenos Aires1.00.0050466See
CHLChile Santiago Mixed1.00.005070See
USAUSA Colorado Univ Cord Blood Bank Asian0.0050100See
SAUSaudi Arabia Guraiat and Hail1.00.0050213See
PERPeru Titikaka Lake Uro0.0050105See
PERPeru Titikaka Lake Uros0.0050105See
GEOGeorgia Caucasus Tbilisi0.0042119See
USAUSA NMDP Hawaiian or other Pacific Islander0.004111499See
PRTAzores Terceira Island0.0040130See
USAUSA Mexican American Mestizo pop 30.0040116See
ISRIsrael Libyan Jews0.0040119See
FRAFrance Southeast0.80.0040130See
KORSouth Korea pop 110.0030149See
RUSRussia Northwest Slavic0.0030200See
PNGPapua New Guinea South Gidra0.0030192See
USAUSA NMDP North American Amerindian0.002935791See
USAUSA Asian pop 20.00281772See
USAUSA NMDP Caribean Hispanic0.0027115374See
BRABrazil Paraná Caucasian0.50.0023641See
CHLChile Santiago0.0022920See
USAUSA NMDP Caribean Indian0.002014339See
USAUSA Eastern European0.0020558See
TURTurkey pop 10.0020250See
COLColombia Bogotá Cord Blood0.30.00141463See
SAUSaudi Arabia pop 6 (G)0.001128927See
DEUGermany DKMS - Turkey minority0.00114856See
INDIndia West UCBB0.20.00105829See
LKASri Lanka Colombo0.30.0010714See
AREUnited Arab Emirates Pop 10.0010570See
USAUSA NMDP Alaska Native or Aleut0.00101376See
USAUSA Colorado Univ Cord Blood Bank Caucasian0.00103830See
USAUSA NMDP Middle Eastern or North Coast of Africa0.000770890See
USAUSA NMDP Southeast Asian0.000627978See
INDIndia Central UCBB0.10.00064204See
USAUSA NMDP Filipino0.000550614See
CHESwitzerland Luzern0.00051553See
USAUSA NMDP South Asian Indian0.0005185391See
INDIndia North UCBB0.10.00045849See
INDIndia East UCBB0.10.00042403See
DEUGermany DKMS - Portugal minority0.00041176See
DEUGermany DKMS - Romania minority0.00041234See
INDIndia South UCBB0.10.000411446See
ISRIsrael Ethiopia Jews0.00035928See
ISRIsrael Arab pop 20.000312301See
ISRIsrael Morocco Jews0.000336718See
DEUGermany DKMS - China minority0.00041282See
DEUGermany DKMS - Netherlands minority0.00041374See
ISRIsrael Argentina Jews0.00024307See
ISRIsrael Ashkenazi Jews pop 30.00024625See
USAUSA NMDP European Caucasian0.00021242890See
CHNChina Jiangsu Han0.00023238See
ISRIsrael Kavkazi Jews0.00022840See
USAUSA NMDP Chinese0.000299672See
HKGHong Kong Chinese cord blood registry0.00013892See
ISRIsrael Iraq Jews0.000113270See
USAUSA NMDP African American pop 20.0001416581See
DEUGermany pop 60.00018862See
ESPSpain (Catalunya, Navarra, Extremadura, Aaragón, Cantabria,0.00.00014335See
ISRIsrael USA Jews0.00016058See
HKGHong Kong Chinese BMDR0.00017595See
DEUGermany DKMS - German donors0.00013456066See
USAUSA NMDP Caribean Black0.000133328See
USAUSA NMDP African0.000028557See
ISRIsrael USSR Jews0.000045681See
ISRIsrael YemenJews0.000015542See
USAUSA NMDP Vietnamese0.000043540See
SDNSudan Mixed0.00.0000200See
USAUSA Caucasian0.00.000061655See
USAUSA San Antonio Caucasian0.0000222See
USAUSA Alaska Yupik0.0000252See
USAUSA Colorado Univ Cord Blood Bank African American0.0000261See
POLPoland DKMS0.000120653See
NIRIreland Northern0.00.00001000See
NLDNetherlands Leiden0.00001305See
RUSRussia Tuva pop30.000044See
RUSRussia Tuva Todja0.000022See
RUSRussia Siberia Irkutsk Tofalar0.000043See
RUSRussia Siberia Kushun Buryat0.000025See
RUSRussia Siberia Khanty Mansi0.000068See
RUSRussia Siberia Negidal0.000035See
RUSRussia Siberia Khabarovsk Evenki0.000025See
MKDMacedonia pop 10.0000158See
MNGMongolia Hoton0.000085See
MNGMongolia Khalkha pop 20.0000202See
USAUSA Caucasian Houston0.00.0000194See
USAUSA Caucasian Pittsburgh0.00.0000177See
USAUSA Caucasian Bethesda0.00.0000307See
USAUSA African American Bethesda0.00.0000187See
USAUSA Philadelphia Caucasian0.00.0000141See
USAUSA African American pop 40.00002411See
ISRIsrael Iranian Jews0.0000101See
ISRIsrael Ethiopian Jews0.0000122See
ISRIsrael Yemenite Jews0.000076See
ISRIsrael Arab0.0000109See
ITAItaly Rome0.00.0000100See
ITAItaly North pop 30.00.000097See
ITAItaly Bergamo0.00.0000101See
ITAItaly pop 50.0000975See
KORSouth Korea pop 20.00.0000207See
ENGEngland Bedfordshire0.00.0000354See
ESPSpain Barcelona0.00.0000941See
ESPSpain Murcia0.0000173See
FRAFrance West0.00.0000100See
DEUGermany pop 80.000039689See
CHNChina Urumqi Uyghur0.00.000057See
CHNChina Harbin Manchu0.0000172See
CHNChina Yunnan Province Lahu0.000070See
CODCongo Kinshasa Bantu0.00.000090See
COLColombia Bogota and Medellin Mestizo0.000065See
CZECzech Republic0.0000106See
CHESwitzerland St Gallen0.00002113See
CHESwitzerland Sion0.0000832See
CHESwitzerland Zurich0.00004875See
BRABrazil Vale do Ribeira Quilombos0.00.0000144See
BRABrazil Central Plateau Xavante0.000074See
BRABrazil Mato Grosso do Sul0.0000203See
CAFCentral African Republic Aka Pygmy0.00.000093See
CANCanada British Columbia Athabaskan0.000062See
CANCanada British Columbia Penutian0.000026See
CHESwitzerland Aargau-Solothurn0.00001838See
CHESwitzerland Bern0.00003545See
CHESwitzerland Basel0.00001888See
CHESwitzerland Geneva pop 20.00001267See
CHESwitzerland Graubunden0.0000759See
CHESwitzerland Lugano0.00001169See
CHESwitzerland Lausanne0.0000993See
ARGArgentina Rio Negro Mapuche0.000034See
ARGArgentina Chubut Tehuelche0.000023See
BRABrazil Guarani Nandeva0.000086See
BRABrazil North East Mixed0.0000205See
BRABrazil Kaingang0.0000235See
BRABrazil Guarani M bya0.000093See
BRABrazil Southeast Caucasian0.00.0000103See

Frequency data at lower resolution for this allele can be found in links below

Allele  Number of Populations 


* Allele Frequency: Total number of copies of the allele in the population sample (Alleles / 2n) in decimal format.
   Important: This field has been expanded to four decimals to better represent frequencies of large datasets (e.g. where sample size > 1000 individuals)
* Phenotype Frequency: Percentage of individuals who have the allele or gene (Individuals / n).
* Allele Frequencies shown in green were calculated from Phenotype Frequencies assuming Hardy-Weinberg proportions.

¹ IMGT/HLA Database - For more details of the allele.
² Distribution - Graphical distribution of the allele.
³ Haplotype Association - Find HLA haplotypes with this allele.
ª Notes - See notes for ambiguous combinations of alleles.


Allele frequency net database (AFND) 2020 update: gold-standard data classification, open access genotype data and new query tools
Gonzalez-Galarza FF, McCabe A, Santos EJ, Jones J, Takeshita LY, Ortega-Rivera ND, Del Cid-Pavon GM, Ramsbottom K, Ghattaoraya GS, Alfirevic A, Middleton D and Jones AR Nucleic Acid Research 2020, 48:D783-8.
Liverpool, U.K.

Valid XHTML 1.0 Transitional