Allele Frequencies in World Populations

HLA Database » Allele Report

The list below shows all populations in AFND that contains the allele. If an allele has an entry with a lower resolution this will be shown at the end.



Allele reported 406 time(s) and present in 345 population(s).

Population Phenotype
Frequency (%)
Distribution² Haplotype³
COLColombia North Eastern Plains Sikuani0.389027See
BRABrazil Guarani M bya0.371093See
BRABrazil Guarani Kaiowa0.3390155See
COLColombia West Waunana0.333030See
COLColombia West Embera0.325020See
MEXMexico Oaxaca Mixe0.309055See
BRABrazil Central Plateau Xavante0.303074See
BRABrazil Guarani Nandeva0.296086See
PNGPapua New Guinea Lowland Wosera0.288079See
MYSMalaysia Sarawak Bau Bidayuh0.280025See
BRABrazil Terena47.50.271060See
SGPSingapore SGVP Malay MAS0.269089See
MYSMalaysia Sarawak Bidayuh0.250050See
BRABrazil Ticuna0.245050See
BRABrazil Puyanawa39.30.2430150See
COLColombia Jaidukama0.231039See
PNGPapua New Guinea Dorogori0.220059See
PNGPapua New Guinea Lowland Roro0.212026See
MYSMalaysia Jelebu Temuan0.208025See
CRICosta Rica and Panama Mestizo0.200056See
SGPSingapore SGVP Chinese CHS0.200096See
VNMVietnam HoaBinh Muong0.199083See
PNGPapua New Guinea Wonie0.196051See
USAUSA New Mexico Zuni0.190051See
MEXMexico Oaxaca Zapotec0.188090See
MEXMexico Oaxaca Mixtec0.1840103See
MEXMexico Mazatecan0.183089See
MEXMexico Mixtec0.180097See
ARGArgentina Chiriguano33.90.179054See
COLColombia Wayu from Guajira Peninsula0.177148See
MEXMexico Oaxaca Jamiltepec Mixtec0.177096See
ARGArgentina Mapuche0.163048See
PNGPapua New Guinea South Gidra0.1620192See
ARGArgentina Rio Negro Mapuche0.161034See
MYSMalaysia Pahang Semai29.00.158038See
CHNChina Southwest Dai0.1530124See
PNGPapua New Guinea Madang0.146065See
COLColombia Guajira Peninsula Wayuu0.143088See
THAThailand North Dai Lue0.141096See
PNGPapua New Guinea Iamega0.133079See
PNGPapua New Guinea Ume0.133090See
PNGPapua New Guinea Wuroi0.132034See
CHNChina Guangxi Region Maonan0.1300108See
BRABrazil Kaingang0.1250235See
USAUSA Arizona Pima pop20.118018See
MYSMalaysia Sarawak Iban0.118051See
USAUSA South Dakota Sioux0.1150101See
USAUSA New Mexico Canoncito Navajo0.113042See
PNGPapua New Guinea Rual0.110050See
MEXMexico Nahua/Aztec Santo Domingo Ocotitlan0.109673See
PNGPapua New Guinea Wipim0.109055See
PNGPapua New Guinea Kapal0.108065See
PNGPapua New Guinea Podare0.105043See
AREUnited Arab Emirates Pop 10.1000570See
PNGPapua New Guinea Kuru0.098046See
USAUSA Arizona Gila River Amerindian0.0920492See
PNGPapua New Guinea Abam0.087063See
MEXMexico Chichen Itza Maya (prehispanic)0.085147See
MYSMalaysia Peninsular Chinese16.00.0851194See
MEXMexico San Vicente Tancuayalab Teenek/Huastecos0.084953See
MEXMexico Huasteca Region Teenek0.083055See
VENVenezuela Sierra de Perija Yucpa0.080073See
MYSMalaysia Patani16.00.080025See
ECUEcuador Cayapa0.0790183See
MEXMexico Veracruz Xalapa15.50.077484See
COLColombia West Cauca0.075020See
COLColombia East Amazon Region Nukak0.075020See
THAThailand Northeast pop 20.0750400See
BRABrazil East Amazon0.073041See
BORBorneo Bandjarmasin0.071021See
RUSRussia Siberia Chukotka Peninsula Eskimo0.070080See
CHLChile Mapuche0.069266See
MEXMexico Guanajuato and Jalisco Mestizo13.90.0690101See
THAThailand Kamphaeng Phet0.067097See
PNGPapua New Guinea East New Britain Rabaul0.067060See
THAThailand Northeast0.065066See
MEXMexico Chiapas Lacandon Mayans0.0642218See
MEXMexico Mexico City Mestizo pop 20.0641234See
CHNChina Hong Kong and Singapore0.0630135See
IRNIran Fars Parsi0.062073See
CZECzech Republic Romani11.80.060834See
IRNIran Baloch0.0600100See
PRYParaguay Lengua0.059017See
TWNTaiwan pop10.0580539See
AREUnited Arab Emirates Abu Dhabi0.057752See
PERPeru Quechua0.057044See
TWNTaiwan Tzu Chi Cord Blood Bank0.0570710See
MEXMexico Highlands Mestizos11.30.0560160See
HKGHong Kong Chinese cord blood registry0.05513892See
TWNTaiwan Tzu Chi Morrow Donor Registry0.054646682See
CHNChina Wuhan10.70.0540121See
HKGHong Kong Chinese BMDR0.05377595See
CHNChina Canton Han0.0530264See
MYSMalaysia Champa10.30.052029See
IDNIndonesia Moluccan Islands0.050024See
TWNTaiwan Han Chinese0.0480504See
BOLBolivia/Peru Quechua NA-DHS_12 (G)9.50.047621See
MEXMexico Mayan pop 20.0460163See
TWNTaiwan Tzu Chi Morrow Donor Registry Aborigine0.0451233See
MEXMexico Mexico City Mestizo pop 30.0450256See
CHNChina pop18.70.0450103See
STPSao Tome Island Forro0.045066See
USAUSA NMDP Chinese0.043599672See
PNGPapua New Guinea Trobriand Island0.043081See
THAThailand Bangkok pop 30.0430187See
USAUSA Mexican American Mestizo pop 30.0430116See
PNGPapua New Guinea East New Britain Tolai0.043048See
COLColombia Bogotá Cord Blood8.40.04271463See
USAUSA African American Bethesda8.40.0420187See
IDNIndonesia Nusa Tenggara Islands0.041049See
MEXMexico Mexico City Tlalpan8.20.0409330See
BOLBolivia La Paz Aymaras0.040087See
IRNIran Azeri0.0400100See
CHNChina Marrow Donor Registry0.0380600See
MYSMalaysia Peninsular Malay7.40.0379951See
RUSRussia Siberia Eskimo0.037070See
MYSMalaysia Kelantan7.10.036028See
CHNChina Hubei Han7.20.03583732See
PNGPapua New Guinea Eastern Highlands Goroka Asaro0.035057See
IRNIran Kurd0.0350100See
CHNChina Urumqi Han0.034059See
ECUEcuadorean Amerindians0.033375See
BRABrazil North East Mixed0.0330205See
JPNJapan Hyogo6.30.031032See
USAUSA Colorado Univ Cord Blood Bank Hispanic0.03101058See
PERPeru Lamas City Lama0.030083See
IDNIndonesia Java Western5.90.0300236See
MEXMexico Jaltepec Mazahuas0.030050See
MEXMexico Mazahua0.030065See
USAUSA NMDP North American Amerindian0.029135791See
PNGPapua New Guinea Highland0.029094See
MKDMacedonia pop 10.0290158See
BRABrazil Southeast Caucasian5.80.0290103See
SGPSingapore Riau Malay0.0280132See
CHLChile Santiago0.0275920See
DEUGermany DKMS - China minority0.02741282See
CHNChina Zhejiang Han pop 20.0270833See
GTMGuatemala Mayan0.0260132See
CHNChina Harbin Manchu0.0260172See
CHLChile Santiago Mixed5.00.025370See
RUSRussia Siberia Chukchi0.025071See
COLColombia Northwest Choco0.025020See
BRABrazil Mato Grosso do Sul0.0250203See
USAUSA NMDP Mexican or Chicano0.0247261235See
GRCGreece pop 84.80.024183See
TWNTaiwan pop 20.0240364See
CHNChina Beijing Shijiazhuang Tianjian Han0.0240618See
BRABrazil Southeast Mixed Race4.80.024042See
USAUSA NMDP American Indian South or Central America0.02405926See
USAUSA NMDP Vietnamese0.023543540See
CHNChina Beijing and Xian0.0230171See
ARGArgentina Gran Chaco Eastern Toba0.0230135See
USAUSA NMDP Hispanic South or Central American0.0220146714See
CHNChina Yunnan Bulang0.0220116See
LBNLebanon Kafar Zubian0.022094See
ARGArgentina Chubut Tehuelche0.022023See
COLColombia North Chimila Amerindians0.021247See
ISRIsrael Libyan Jews0.0210119See
USAUSA Hispanic pop 20.02101999See
BRABrazil South Caucasian0.020873See
GRCGreece pop 60.0207242See
USAUSA Southern California Mestizo4.10.020773See
USAUSA Colorado Univ Cord Blood Bank Asian0.0200100See
CHNChina Harbin Manchu pop 20.020050See
RUSRussia Siberia Chukotka Peninsula Chukchi0.020059See
GTMGuatemala, Guatemala City Mixed Ancestry3.90.0197127See
USAUSA Asian pop 20.01951772See
PNGPapua New Guinea Woigi0.019026See
USAUSA NMDP Alaska Native or Aleut0.01901376See
MYSMalaysia Mandailing3.70.019027See
USAUSA NMDP Southeast Asian0.018927978See
GRCGreece pop33.70.0186246See
VNMVietnam Hanoi Kinh pop 20.0180170See
PNGPapua New Guinea Highland pop20.018028See
MEXMexico Mexico City Mestizo population0.0175143See
MEXMexico Chihuahua Chihuahua City Pop 23.40.017088See
GHAGhana Accre Asutuare Akan0.0170429See
CHNChina Yunnan Province Naxi0.0170118See
IDNIndonesia Java0.017058See
JPNJapan Hyogo Osaka and Nagano0.0170195See
COLColombia Amazon Region Coreguaje0.017030See
CHNChina Jiangsu Han0.01623238See
GRCGreece pop23.30.0160120See
CHNChina Yunnan Province Han pop 20.0160129See
USAUSA African American pop 40.01542411See
USAUSA NMDP Caribean Black0.015033328See
CUBCuba Mixed0.015078See
CHNChina Yunnan Province Han0.0150101See
MKDMacedonia pop 30.0150172See
USAUSA South Texas Hispanic0.0150194See
KORSouth Korea pop 10.0150324See
MEXMexico Tixcacaltuyub Maya0.014967See
BRABrazil Paraná Caucasian3.00.0148641See
GMBGambia pop 32.80.0147939See
ISRIsrael Tunisia Jews0.01469070See
JPNJapan Hokkaido Wajin2.80.014171See
KORSouth Korea pop 42.80.0141211See
RUSRussia Siberia Negidal0.014035See
USAUSA NMDP African American pop 20.0138416581See
USAUSA NMDP African0.013228557See
DEUGermany DKMS - Greece minority0.01321894See
GNQEquatorial Guinea Bioko Island Bubi0.0130100See
GEOGeorgia Svaneti Region Svan0.013080See
RUSRussia Northwest Slavic0.0130200See
CHNChina Yunnan Hani0.0130150See
KORSouth Korea pop 110.0130149See
CHNChina Jiangsu Province Han0.0122334See
MEXMexico Nuevo Leon Mestizo2.50.012040See
MKDMacedonia pop 20.012080See
USAUSA Colorado Univ Cord Blood Bank African American0.0120261See
AUSAustralia Kimberly Aborigine0.012041See
COLColombia San Basilio de Palenque0.012042See
INDIndia Northeast UCBB2.40.0118296See
JPNJapan pop 62.30.0115129See
INDIndia North2.30.011585See
ISRIsrael Kavkazi Jews0.01122840See
ISRIsrael Druze0.01115914See
KORSouth Korea pop 100.01114128See
JPNJapan Aichi2.20.011050See
RUSRussia Tuva pop30.011044See
INDIndia Delhi0.0110112See
HRVCroatia pop 40.01014000See
ARMArmenia combined Regions0.0100100See
MNGMongolia Khalkha pop 20.0100202See
PRTPortugal Center0.010050See
ITAItaly North pop 32.10.010097See
AUSAustralia Cape York Peninsula Aborigine0.0100103See
VNMVietnam Hanoi Kinh0.0100103See
ESPSpain Andalusia Romani0.010099See
ISRIsrael Iranian Jews0.0100101See
TUNTunisia pop 30.0100104See
TWNTaiwan Aborigine pop 20.010048See
BRABrazil Mixed0.0100108See
DZAAlgeria Oran0.0100100See
MYSMalaysia Sabah Dusun0.010048See
USAUSA African American pop 70.0100193See
USAUSA NMDP Korean0.009977584See
USAUSA NMDP Caribean Hispanic0.0096115374See
ISRIsrael Libya Jews0.00963739See
USAUSA NMDP Caribean Indian0.009014339See
JPNJapan pop 160.009018604See
PRTAzores Central Islands0.009059See
ZWEZimbabwe Harare Shona0.0090230See
KORSouth Korea pop 60.0090800See
FJIFiji Viti Levu Island0.009057See
JPNJapan Central0.0090371See
USAUSA NMDP Filipino0.008650614See
GEOGeorgia Caucasus Tbilisi0.0084119See
ISRIsrael Ashkenazi Jews pop 20.0080132See
IRNIran Yazd Zoroastrian0.008065See
NCLNew Caledonia0.008065See
COLColombia Bogota and Medellin Mestizo0.008065See
SDNSudan Mixed1.50.0080200See
NLDNetherlands UMCU1.60.007864See
DEUGermany DKMS - Turkey minority0.00704856See
SVNSlovenia pop 21.40.0070140See
ARGArgentina Buenos Aires1.40.0070466See
CHNChina Harbin Korean0.0070201See
USAUSA San Diego1.40.0070496See
LKASri Lanka Colombo1.40.0070714See
INDIndia North UCBB1.40.00685849See
USAUSA NMDP South Asian Indian0.0067185391See
USAUSA NMDP Japanese0.006724582See
DEUGermany DKMS - Croatia minority0.00662057See
USAUSA NMDP Middle Eastern or North Coast of Africa0.006670890See
JPNJapan pop 170.00653078See
USAUSA NMDP Hawaiian or other Pacific Islander0.006211499See
INDIndia West UCBB1.20.00625829See
INDIndia East UCBB1.20.00602403See
NICNicaragua Managua1.20.0060339See
JPNJapan Kyoto and Osaka0.0060165See
TUNTunisia Ghannouch0.006082See
JPNJapan pop 20.0060916See
KORSouth Korea pop 30.0060485See
ARGArgentina Rosario Toba1.20.006086See
CODCongo Kinshasa Bantu1.10.006090See
ISRIsrael Non Ashkenazi Jews0.006080See
INDIndia Central UCBB1.10.00564204See
DEUGermany DKMS - Portugal minority0.00551176See
DEUGermany DKMS - Romania minority0.00531234See
ITAItaly pop 50.0050975See
USAUSA Philippines0.0050105See
JPNJapan pop 30.00501018See
JPNJapan pop 41.00.0050525See
CHNChina Xinjiang Province Uyghur0.005092See
ESPSpain Barcelona1.00.0050941See
MNGMongolia Khalkha0.0050200See
DEUGermany DKMS - Bosnia and Herzegovina minority0.00491028See
DEUGermany DKMS - Italy minority0.00481159See
JPNJapan South0.80.0040125See
MYSMalaysia Peninsular Indian0.70.0037271See
ESPSpain (Catalunya, Navarra, Extremadura, Aaragón, Cantabria,0.70.00364335See
DEUGermany DKMS - Spain minority0.00361107See
INDIndia South UCBB0.60.003211446See
RUSRussia Transbaikal Territory Buryats1.00.0030150See
ZAFSouth Africa Worcester1.00.0030159See
NZLNew Zealand Maori0.0030200See
USAUSA Caucasian Bethesda0.60.0030307See
GABGabon Haut-Ogooue Dienga0.0030167See
USAUSA Colorado Univ Cord Blood Bank Caucasian0.00303830See
ISRIsrael YemenJews0.002715542See
INDIndia Tamil Nadu0.00252492See
DEUGermany DKMS - Austria minority0.00241698See
DEUGermany pop 80.002439689See
RUSRussia Karelia0.00241075See
CZECzech Republic NMDR0.00235099See
USAUSA San Francisco Caucasian0.0020220See
USAUSA Eastern European0.0020558See
SAUSaudi Arabia Guraiat and Hail0.50.0020213See
IRLIreland South0.40.0020250See
RWARwanda Kigali Hutu and Tutsi0.0020281See
DEUGermany DKMS - Netherlands minority0.00181374See
DEUGermany pop 60.00178862See
ISRIsrael Arab pop 20.001612301See
DEUGermany DKMS - German donors0.00153456066See
ISRIsrael Argentina Jews0.00154307See
USAUSA NMDP European Caucasian0.00151242890See
POLPoland DKMS0.001320653See
ISRIsrael Ashkenazi Jews pop 30.00114625See
ISRIsrael USA Jews0.00116058See
ITAItaly Central0.0010380See
ISRIsrael Poland Jews0.000913871See
ISRIsrael USSR Jews0.000945681See
ISRIsrael Iran Jews0.00098153See
DEUGermany DKMS - France minority0.00071406See
ISRIsrael Georgia Jews0.00064471See
ISRIsrael Morocco Jews0.000436718See
DEUGermany DKMS - United Kingdom minority0.00051043See
ISRIsrael Iraq Jews0.000213270See
ISRIsrael Ethiopia Jews0.00015928See
ISRIsrael Bukhara Jews0.00002317See
BRABrazil Vale do Ribeira Quilombos0.00.0000144See
NLDNetherlands Leiden0.00001305See
SGPSingapore SGVP. Indian INS0.000086See
ZAFSouth Africa Caucasians0.0000102See
STPSao Tome Island Angolar0.000032See
USAUSA Caucasian pop 40.00001070See
CZECzech Republic pop 20.00.000099See
FRAFrance Rennes pop 30.0000200See
INDIndia Tamil Nadu Chennai0.00.0000137See
ARGArgentina Salta Wichi0.000024See
WSMSamoa West0.000022See
IDNIndonesia Singaporean0.000050See
PNGPapua New Guinea Lowland0.000047See
PRTAzores Oriental Islands0.000043See
GRCGreece pop 40.000098See
JPNJapan pop 110.00.000062See
ISRIsrael Ethiopian Jews0.0000122See
ISRIsrael Yemenite Jews0.000076See
ISRIsrael Arab0.0000109See
MNGMongolia Oold0.0000104See
MNGMongolia Tsaatan0.0000144See
CZECzech Republic0.0000106See
ITAItaly Bergamo0.00.0000101See
USAUSA San Antonio Caucasian0.0000222See
KORSouth Korea pop 20.00.0000207See
ESPSpain Murcia0.0000173See
CANCanada British Columbia Athabaskan0.000062See
CANCanada British Columbia Penutian0.000026See
PRTPortugal North0.000046See
PRTPortugal South0.000049See
ITAItaly Rome0.00.0000100See
FRAFrance West0.00.0000100See
USAUSA Caucasian Houston0.00.0000194See
USAUSA Caucasian Pittsburgh0.00.0000177See
CAFCentral African Republic Aka Pygmy0.00.000093See
DZAAlgeria pop 20.00.0000106See
ARGArgentina Gran Chaco Mataco Wichi0.000049See
ARGArgentina Gran Chaco Western Toba Pilaga0.000019See
PRYParaguay Aché0.000087See
ISRIsrael Moroccan Jews0.0000113See
RUSRussia Siberia Sulamai Ket0.000022See
RUSRussia Siberia Polygus Evenk0.000035See
RUSRussia Siberia North East Kamchatka Koryak0.000092See
RUSRussia Siberia Gvaysugi Udege0.000025See
RUSRussia Siberia NW of Sakhalin Island Nivkh0.000032See
CHNChina Urumqi Kazak0.000042See
CHNChina Urumqi Uyghur0.00.000057See
MNGMongolia Hoton0.000085See
LBNLebanon Niha el Shouff0.000061See
LBNLebanon Yuhmur0.000082See
JPNJapan Nagano0.00.000057See
RUSRussia Tuva Todja0.000022See
RUSRussia Siberia Irkutsk Tofalar0.000043See
RUSRussia Siberia Kushun Buryat0.000025See
RUSRussia Siberia Khanty Mansi0.000068See
RUSRussia Siberia Ulchi0.000073See
RUSRussia Siberia Khabarovsk Evenki0.000025See
USAUSA Philadelphia Caucasian0.00.0000141See

Frequency data at lower resolution for this allele can be found in links below

Allele  Number of Populations 


* Allele Frequency: Total number of copies of the allele in the population sample (Alleles / 2n) in decimal format.
   Important: This field has been expanded to four decimals to better represent frequencies of large datasets (e.g. where sample size > 1000 individuals)
* Phenotype Frequency: Percentage of individuals who have the allele or gene (Individuals / n).
* Allele Frequencies shown in green were calculated from Phenotype Frequencies assuming Hardy-Weinberg proportions.

¹ IMGT/HLA Database - For more details of the allele.
² Distribution - Graphical distribution of the allele.
³ Haplotype Association - Find HLA haplotypes with this allele.
ª Notes - See notes for ambiguous combinations of alleles.


Allele frequency net database (AFND) 2020 update: gold-standard data classification, open access genotype data and new query tools
Gonzalez-Galarza FF, McCabe A, Santos EJ, Jones J, Takeshita LY, Ortega-Rivera ND, Del Cid-Pavon GM, Ramsbottom K, Ghattaoraya GS, Alfirevic A, Middleton D and Jones AR Nucleic Acid Research 2020, 48:D783-8.
Liverpool, U.K.

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