Populations » Add New HLA Population Study


This page is for the submission of primary genotyping data (at individual level), such as that described by a Short Population report for Human Immunology (see here for an introduction to the required format or here for recent reports).

From 1 April 2022, Human Immunology has decided, in light of the advancements in HLA allele detection, that data submitted to AFND, with intention of writing a SPR, MUST have been tested by molecular methods and to at least two field (four digit) level. Other data can still be submitted to AFND and will be judged on merit. For example, uniqueness of the population.

If your study contains frequencies only (and no individual-level data) for HLA, please click here.

To get started - you may wish to view our video tutorials (best viewed in HD)

Please provide the data of your population by using the Java Upload Tool.

Click here to download the latest version (1.18) of the upload tool or (UK Mirror)

Help with using the upload tool is available here.

This tool will allow you to format and validate your data for submission to the Allele Frequencies Net Database.
The 'SampleFiles.zip' file contains template files that can be edited with Microsoft Excel, and then loaded in to the Allele Frequencies Upload Tool.

This is an executable Java (.jar) file. You will need to have a 'Java Runtime Environment' installed on your computer. Most computers will already have this installed, but you can download compatible versions here or here.

(With some browsers, such as Chrome, you will see a warning that the browser 'might be unable to use the Java plugin'. You can ignore this warning, as the AFND upload tool does not use a browser plugin. Depending on your browser, you can check your current Java version automatically here, or manually here )



Allele Frequencies Net upload tool
Link AFNDTool.jar
Version 1.18 (Latest)
Date 21/10/2019
Requirements Java Runtime Version 1.6 or above
Northern Ireland Sample population
HLA Data Link SampleData.zip
KIR Data Link SampleDataKIR.zip
Sample File Templates
Link SampleFiles.zip

Allele frequency net database (AFND) 2020 update: gold-standard data classification, open access genotype data and new query tools
Gonzalez-Galarza FF, McCabe A, Santos EJ, Jones J, Takeshita LY, Ortega-Rivera ND, Del Cid-Pavon GM, Ramsbottom K, Ghattaoraya GS, Alfirevic A, Middleton D and Jones AR Nucleic Acid Research 2020, 48:D783-8.
Liverpool, U.K.


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