Allele Frequencies in World Populations

HLA Database Allele Report

The list below shows all populations in AFND that contains the allele. If an allele has an entry with a lower resolution this will be shown at the end.



Allele reported 20 time(s) and present in 20 population(s).

Population Phenotype
Frequency (%)
Distribution² Haplotype³
ESPSpain, Canary Islands, Gran canaria island4.70.0256215See
ZAFSouth African Black4.90.0247142See
ZAFSouth African Mixed ancestry4.00.020050See
BRABrazil Rio de Janeiro Caucasian0.0182521See
BRABrazil Barra Mansa Rio State Caucasian0.0173405See
BRABrazil Rio de Janeiro Parda0.0147170See
ENGEngland Blood Donors of Mixed Ethnicity2.30.0116519See
CRICosta Rica African -Caribbean (G)2.00.0100102See
ZAFSouth African Indian population2.00.010050See
MEXMexico Hidalgo Mezquital Valley/ Otomi1.40.006972See
CRICosta Rica Guanacaste Mestizo (G)1.00.0050110See
CRICosta Rica Central Valley Mestizo (G)1.00.0050221See
RUSRussian Federation Vologda Region0.80.0042119See
LBYLibya Cyrenaica0.0040118See
RUSRussia Belgorod region0.70.0033153See
POLPoland BMR0.60.003223595See
SAUSaudi Arabia pop 50.60.0032158See
NICNicaragua Mestizo (G)0.60.0030155See
RUSRussia Nizhny Novgorod, Russians0.30.00131510See
USAUSA Arizona Gila River Pima0.00023000See

Frequency data at lower resolution for this allele can be found in links below

Allele  Number of Populations 


* Allele Frequency: Total number of copies of the allele in the population sample (Alleles / 2n) in decimal format.
   Important: This field has been expanded to four decimals to better represent frequencies of large datasets (e.g. where sample size > 1000 individuals)
* Phenotype Frequency: Percentage of individuals who have the allele or gene (Individuals / n).
* Allele Frequencies shown in green were calculated from Phenotype Frequencies assuming Hardy-Weinberg proportions.

¹ IMGT/HLA Database - For more details of the allele.
² Distribution - Graphical distribution of the allele.
³ Haplotype Association - Find HLA haplotypes with this allele.
ª Notes - See notes for ambiguous combinations of alleles.

Allele frequency net database (AFND) 2020 update: gold-standard data classification, open access genotype data and new query tools
Gonzalez-Galarza FF, McCabe A, Santos EJ, Jones J, Takeshita LY, Ortega-Rivera ND, Del Cid-Pavon GM, Ramsbottom K, Ghattaoraya GS, Alfirevic A, Middleton D and Jones AR Nucleic Acid Research 2020, 48:D783-8.
Liverpool, U.K.

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